A J Larner

Summary

Affiliation: Christie Hospital
Country: UK

Publications

  1. ncbi request reprint Gardening and dementia
    A J Larner
    Int J Geriatr Psychiatry 20:796-7. 2005
  2. ncbi request reprint Alzheimer's disease: targets for drug development
    A J Larner
    Cognitive Function Clinic, Walton Centre for Neurology and Neurosurgery, Lower Lane, Fazakerley, Liverpool, L9 7LJ, UK
    Mini Rev Med Chem 2:1-9. 2002
  3. ncbi request reprint Pathological heterogeneity of clinically diagnosed corticobasal degeneration
    M Doran
    Cognitive Function Clinic, Walton Centre for Neurology and Neurosurgery, Lower Lane, Fazakerley, L9 7LJ, Liverpool, UK
    J Neurol Sci 216:127-34. 2003
  4. ncbi request reprint Did Charles Dickens describe progressive supranuclear palsy in 1857?
    A J Larner
    Walton Centre for Neurology and Neurosurgery, Liverpool, United Kingdom
    Mov Disord 17:832-3. 2002
  5. ncbi request reprint The place of the ice pack test in the diagnosis of myasthenia gravis
    A J Larner
    Walton Centre for Neurology and Neurosurgery, Fazakerly, Liverpool, UK
    Int J Clin Pract 58:887-8. 2004
  6. ncbi request reprint Charles Meller and John Kirk: medical practitioners and practice on Livingstone's Zambesi expedition, 1858-64
    A J Larner
    Walton Centre for Neurology and Neurosurgery, Lower Lane, Liverpool L9 7LJ, UK
    J Med Biogr 10:129-34. 2002
  7. ncbi request reprint Use of the internet and of the NHS direct telephone helpline for medical information by a cognitive function clinic population
    A J Larner
    Cognitive Function Clinic, Walton Centre for Neurology and Neurosurgery, Lower Lane, Fazakerley, Liverpool L9 7LJ, UK
    Int J Geriatr Psychiatry 18:118-22. 2003
  8. ncbi request reprint Concurrent syrinx and inflammatory central nervous system disease detected by magnetic resonance imaging: an illustrative case and review of the literature
    A J Larner
    Department of Molecular Pathogenesis, Institute of Neurology, Queen Square, London, WCIN 3BG, UK
    Medicine (Baltimore) 81:41-50. 2002
  9. ncbi request reprint Myelopathy following influenza vaccination in inflammatory CNS disorder treated with chronic immunosuppression
    A J Larner
    Department of Neurology, St Mary s Hospital, Praed Street, London, UK
    Eur J Neurol 7:731-3. 2000
  10. ncbi request reprint Isolated familial hypomagnesaemia with novel neurological features: causal link or chance concurrence?
    A J Larner
    St Mary s Hospital, Praed Street, London, UK
    Eur J Neurol 8:495-9. 2001

Collaborators

Detail Information

Publications91

  1. ncbi request reprint Gardening and dementia
    A J Larner
    Int J Geriatr Psychiatry 20:796-7. 2005
  2. ncbi request reprint Alzheimer's disease: targets for drug development
    A J Larner
    Cognitive Function Clinic, Walton Centre for Neurology and Neurosurgery, Lower Lane, Fazakerley, Liverpool, L9 7LJ, UK
    Mini Rev Med Chem 2:1-9. 2002
    ..This article gives a broad overview of the spectrum of targets for AD treatment, with particular emphasis on amyloid beta-peptides and tau protein...
  3. ncbi request reprint Pathological heterogeneity of clinically diagnosed corticobasal degeneration
    M Doran
    Cognitive Function Clinic, Walton Centre for Neurology and Neurosurgery, Lower Lane, Fazakerley, L9 7LJ, Liverpool, UK
    J Neurol Sci 216:127-34. 2003
    ....
  4. ncbi request reprint Did Charles Dickens describe progressive supranuclear palsy in 1857?
    A J Larner
    Walton Centre for Neurology and Neurosurgery, Liverpool, United Kingdom
    Mov Disord 17:832-3. 2002
    ..A character from one of Charles Dickens's lesser known works is presented, whose attributes suggest a possible diagnosis of progressive supranuclear palsy...
  5. ncbi request reprint The place of the ice pack test in the diagnosis of myasthenia gravis
    A J Larner
    Walton Centre for Neurology and Neurosurgery, Fazakerly, Liverpool, UK
    Int J Clin Pract 58:887-8. 2004
    ..Pooling of published studies suggests very high sensitivity, specificity and likelihood ratios, but standardisation and operationalisation of the test are important. False-negative tests may occasionally occur...
  6. ncbi request reprint Charles Meller and John Kirk: medical practitioners and practice on Livingstone's Zambesi expedition, 1858-64
    A J Larner
    Walton Centre for Neurology and Neurosurgery, Lower Lane, Liverpool L9 7LJ, UK
    J Med Biogr 10:129-34. 2002
  7. ncbi request reprint Use of the internet and of the NHS direct telephone helpline for medical information by a cognitive function clinic population
    A J Larner
    Cognitive Function Clinic, Walton Centre for Neurology and Neurosurgery, Lower Lane, Fazakerley, Liverpool L9 7LJ, UK
    Int J Geriatr Psychiatry 18:118-22. 2003
    ..Internet websites and medical telephone helplines are relatively new and huge resources of medical information ("cybermedicine" and "telemedicine", respectively) accessible to the general public without prior recourse to a doctor...
  8. ncbi request reprint Concurrent syrinx and inflammatory central nervous system disease detected by magnetic resonance imaging: an illustrative case and review of the literature
    A J Larner
    Department of Molecular Pathogenesis, Institute of Neurology, Queen Square, London, WCIN 3BG, UK
    Medicine (Baltimore) 81:41-50. 2002
  9. ncbi request reprint Myelopathy following influenza vaccination in inflammatory CNS disorder treated with chronic immunosuppression
    A J Larner
    Department of Neurology, St Mary s Hospital, Praed Street, London, UK
    Eur J Neurol 7:731-3. 2000
    ..Although influenza vaccination is recommended in patients receiving chronic immunosuppression, its use may on occasion be associated with neurological complications previously reported in immunocompetent individuals...
  10. ncbi request reprint Isolated familial hypomagnesaemia with novel neurological features: causal link or chance concurrence?
    A J Larner
    St Mary s Hospital, Praed Street, London, UK
    Eur J Neurol 8:495-9. 2001
    ..The pathogenesis of this unusual neurological and ophthalmological syndrome therefore remains uncertain...
  11. pmc A developing visual field defect
    A J Larner
    Walton Centre for Neurology and Neurosurgery, Lower Lane, Fazakerley, Liverpool L9 7LJ, UK
    Postgrad Med J 78:106, 112-3. 2002
  12. ncbi request reprint Clinical phenotypic heterogeneity of Alzheimer's disease associated with mutations of the presenilin-1 gene
    A J Larner
    Cognitive Function Clinic, Walton Centre for Neurology and Neurosurgery Fazakerley, Liverpool, UK
    J Neurol 253:139-58. 2006
    ..This article reviews the clinical phenotypes of reported PSEN1 mutations, emphasizing their heterogeneity, and suggesting that other factors, both genetic and epigenetic,must contribute to disease phenotype...
  13. doi request reprint Screening utility of the Montreal Cognitive Assessment (MoCA): in place of--or as well as--the MMSE?
    A J Larner
    Cognitive Function Clinic, Walton Centre for Neurology and Neurosurgery, Liverpool, UK
    Int Psychogeriatr 24:391-6. 2012
    ....
  14. doi request reprint Referrals to the neurology clinic from oral and maxillofacial surgery clinics
    A J Larner
    Walton Centre for Neurology and Neurosurgery, Lower Lane, Fazakerley, Liverpool, L9 7LJ, UK
    Br J Oral Maxillofac Surg 49:576-7. 2011
    ....
  15. ncbi request reprint Acute amnesia in MS revisited
    A J Larner
    Cognitive Function Clinic, Walton Centre for Neurology and Neurosurgery, Lower Lane, Fazakerley, Liverpool, L9 7LJ, UK
    Int MS J 16:102-4. 2009
    ..Nonetheless, as illustrated by the following case report, acute onset of demyelinating disease with the clinical phenotype of amnesia may on occasion be the presenting feature of MS...
  16. doi request reprint Use of cognitive screening instruments in primary care: the impact of national dementia directives (NICE/SCIE, National Dementia Strategy)
    R Menon
    Cognitive Function Clinic, Walton Centre for Neurology and Neurosurgery, Liverpool, UK
    Fam Pract 28:272-6. 2011
    ....
  17. doi request reprint Intrafamilial clinical phenotypic heterogeneity with MAPT gene splice site IVS10+16C>T mutation
    A J Larner
    Cognitive Function Clinic, Walton Centre for Neurology and Neurosurgery, Lower Lane, Fazakerley, Liverpool L9 7LJ, United Kingdom
    J Neurol Sci 287:253-6. 2009
    ..Possible explanations for the intra- and interfamilial clinical heterogeneity associated with this MAPT mutation are discussed...
  18. ncbi request reprint Use of internet medical websites and NHS direct by neurology outpatients before consultation
    A J Larner
    Walton Centre for Neurology and Neurosurgery, Fazakerley, Liverpool, UK
    Int J Clin Pract 56:219-21. 2002
    ..A comparison was made between patients' searches and their final diagnosis. Patients' views on the use of the information received were sought...
  19. ncbi request reprint DemTect: 1-year experience of a neuropsychological screening test for dementia
    A J Larner
    Cognitive Function Clinic, Walton Centre for Neurology and Neurosurgery, Fazakerley, Liverpool, UK
    Age Ageing 36:326-7. 2007
  20. ncbi request reprint The R269H mutation in presenilin-1 presenting as late-onset autosomal dominant Alzheimer's disease
    A J Larner
    Cognitive Function Clinic, Walton Centre for Neurology and Neurosurgery, Lower Lane, Fazakerley, Liverpool, L9 7LJ, UK
    J Neurol Sci 252:173-6. 2007
    ..Late-onset AD may be associated with deterministic PS1 mutations; these should be sought when the family history suggests autosomal dominant disease transmission...
  21. ncbi request reprint Ophthalmological observations made during the mid-19th-century European encounter with Africa
    A J Larner
    Walton Centre for Neurology and Neurosurgery, Liverpool, United Kingdom
    Arch Ophthalmol 122:267-72. 2004
    ..This affords an opportunity to compare observations made in Saharan and sub-Saharan Africa...
  22. pmc Acupuncture use for the treatment of headache prior to neurological referral
    A J Larner
    Walton Centre for Neurology and Neurosurgery, Lower Lane, Fazakerley, Liverpool L9 7LJ, UK
    J Headache Pain 6:97-9. 2005
    ..In this study, 12% of patients with headache attending general neurology outpatient clinics had already received acupuncture; of the remainder, 73% said they would be willing to try it...
  23. ncbi request reprint Addenbrooke's Cognitive Examination-Revised (ACE-R) in day-to-day clinical practice
    A J Larner
    Cognitive Function Clinic, Walton Centre for Neurology and Neurosurgery, Lower Lane, Fazakerley, Liverpool L9 7LJ, UK
    Age Ageing 36:685-6. 2007
  24. ncbi request reprint Addenbrooke's Cognitive Examination (ACE) for the diagnosis and differential diagnosis of dementia
    A J Larner
    Cognitive Function Clinic, Walton Centre for Neurology and Neurosurgery, Lower Lane, Fazakerley, Liverpool, United Kingdom
    Clin Neurol Neurosurg 109:491-4. 2007
    ..This study measured diagnostic accuracy of ACE in a large cohort of consecutive patients referred to a dedicated Cognitive Function Clinic...
  25. ncbi request reprint Prominent behavioural and psychiatric symptoms in early-onset Alzheimer's disease in a sib pair with the presenilin-1 gene R269G mutation
    M Doran
    Cognitive Function Clinic, Walton Centre for Neurology and Neurosurgery, Lower Lane, Fazakerley, Liverpool, L9 7LJ, UK
    Eur Arch Psychiatry Clin Neurosci 254:187-9. 2004
    ....
  26. doi request reprint Perry syndrome: a disorder to consider in the differential diagnosis of Parkinsonism
    B M Aji
    Walton Centre for Neurology and Neurosurgery, Liverpool, United Kingdom
    J Neurol Sci 330:117-8. 2013
    ..Diagnosis early in the disease course may facilitate monitoring and prompt intervention to avoid potentially fatal respiratory failure...
  27. ncbi request reprint Dr David Livingstone (1813-1873): some neurological observations
    A J Larner
    Walton Centre for Neurology and Neurosurgery, Lower Lane, Fazakerley, Liverpool, L9 7LJ, United Kingdom
    Scott Med J 53:35-7. 2008
  28. pmc Lewis Carroll's Humpty Dumpty: an early report of prosopagnosia?
    A J Larner
    Cognitive Function Clinic, Walton Centre for Neurology and Neurosurgery, Lower Lane, Fazakerley, Liverpool, L9 7LJ, UK
    J Neurol Neurosurg Psychiatry 75:1063. 2004
  29. doi request reprint Jane Austen's (1775-1817) references to headache: fact and fiction
    A J Larner
    Walton Centre for Neurology and Neurosurgery, Lower Lane, Fazakerley, Liverpool L9 7LJ, UK
    J Med Biogr 18:211-5. 2010
    ....
  30. doi request reprint Presenilin-1 mutation Alzheimer's disease: a genetic epilepsy syndrome?
    A J Larner
    Cognitive Function Clinic, Walton Centre for Neurology and Neurosurgery, Liverpool, UK
    Epilepsy Behav 21:20-2. 2011
    ..Nevertheless, PSEN1 AD should now be recognized, using the new International League Against Epilepsy nomenclature, as a genetic epilepsy syndrome...
  31. pmc Upbeat nystagmus: clinicoanatomical correlation
    J C Janssen
    Department of Neurology, St Mary s Hospital, London, UK
    J Neurol Neurosurg Psychiatry 65:380-1. 1998
    ..The conjunction of a vestibular pattern of nystagmus with this focal lesion runs contrary to a previous suggestion that the nucleus intercalatus may act as a neural integrator for vertical conjugate eye movements...
  32. ncbi request reprint David Livingstone's uvulectomy
    A J Larner
    Walton Centre for Neurology and Neurosurgery, Liverpool, UK
    J Med Biogr 14:104-8. 2006
    ..The practice of uvulectomy in indigenous African societies and some contemporary ideas about uvulectomy are also considered in order to try to ascertain why Livingstone elected to undergo this procedure...
  33. ncbi request reprint Prevalence and causes of seizures at the time of diagnosis of probable Alzheimer's disease
    D A Lozsadi
    Walton Centre for Neurology and Neurosurgery, Liverpool, UK
    Dement Geriatr Cogn Disord 22:121-4. 2006
    ..To investigate the frequency of epilepsy at the time of diagnosis of Alzheimer's disease (AD)...
  34. ncbi request reprint Searching the Internet for medical information: frequency over time and by age and gender in an outpatient population in the UK
    A J Larner
    Walton Centre for Neurology and Neurosurgery, Liverpool, UK
    J Telemed Telecare 12:186-8. 2006
    ..Data on health-information-seeking behaviour through Internet searching are relevant not only to clinical consultation, but also to the possibilities of targeting health-related information and to email consultation...
  35. ncbi request reprint Camptodactyly in a neurology outpatient clinic
    A J Larner
    Walton Centre for Neurology and Neurosurgery, Fazakerley, Liverpool, L9 7LJ, UK
    Int J Clin Pract 55:592-5. 2001
    ..Camptodactyly is not infrequently observed in the general neurology outpatient clinic. It merits attention in order to avoid confusion with other, neurogenic, causes of clawing, and so avoid unnecessary investigation...
  36. pmc Referral guidelines for suspected central nervous system or brain tumours
    A J Larner
    Walton Centre for Neurology and Neurosurgery, Lower Lane, Fazakerley, Liverpool L9 7LJ, UK
    J Neurol Neurosurg Psychiatry 77:1305-6. 2006
  37. doi request reprint Late-onset temporal lobe epilepsy with unilateral mesial temporal sclerosis and cognitive decline: a diagnostic dilemma
    D A Lozsadi
    Mersey Regional Epilepsy Clinic, Walton Centre for Neurology and Neurosurgery, Lower Lane, Fazakerley, Liverpool, UK
    Seizure 17:473-6. 2008
    ....
  38. ncbi request reprint Early-onset Alzheimer's disease with presenilin-1 M139V mutation: clinical, neuropsychological and neuropathological study
    A J Larner
    Walton Centre for Neurology and Neurosurgery, Lower Lane, Fazakerley, Liverpool, UK
    Eur J Neurol 10:319-23. 2003
    ..This clinical and pathological heterogeneity in patients with the same PSEN-1 mutation suggests phenotype modulation by genetic and/or epigenetic factors...
  39. ncbi request reprint Disseminated enteropathy-type T-cell lymphoma: cauda equina syndrome complicating coeliac disease
    M Doran
    Walton Centre for Neurology and Neurosurgery, Lower Lane, Fazakerely, Liverpool L9 7LJ, UK
    Clin Neurol Neurosurg 107:517-20. 2005
    ..Although rare, disseminated enteropathy-type T-cell lymphoma should enter the differential diagnosis in any patient with coeliac disease developing new neurological signs...
  40. doi request reprint Francis Kilvert (1840-1879): an early self-report of cluster headache?
    A J Larner
    Walton Centre for Neurology and Neurosurgery, Liverpool, UK
    Cephalalgia 28:763-6. 2008
    ..This may be one of the earliest accounts by a patient, rather than a physician, of cluster headache...
  41. doi request reprint An effective immunotherapy regimen for VGKC antibody-positive limbic encephalitis
    S H Wong
    Department of Neurology, The Walton Centre for Neurology and Neurosurgery, Liverpool, UK
    J Neurol Neurosurg Psychiatry 81:1167-9. 2010
    ..The effectiveness of a combination immunomodulatory regimen was tested in consecutive VGKC+LE patients...
  42. doi request reprint Shaky legs? Think POT!
    J Ramtahal
    Walton Centre for Neurology and Neurosurgery, Lower Lane, Fazakerley, Liverpool, L9 7LJ, UK
    Age Ageing 38:352-3. 2009
    ..Arch Neurol 1984; 41: 880-1). We present three cases seen in a general neurology clinic over a 15-month period to highlight the typical clinical features which should alert clinicians to the possibility of this diagnosis...
  43. doi request reprint Not all morning headaches are due to brain tumours
    A J Larner
    Walton Centre for Neurology and Neurosurgery, Fazakerley, Liverpool, UK
    Pract Neurol 9:80-4. 2009
    ..As ever, history taking is key to the diagnosis. Attention to the possibility of analgesic medication overuse is particularly pertinent, but other treatable conditions such as depression and epilepsy must not be overlooked...
  44. ncbi request reprint Cholinesterase inhibitors: beyond Alzheimer’s disease
    A J Larner
    Walton Centre for Neurology and Neurosurgery, Lower Lane, Fazakerley, Liverpool, L9 7LJ, UK
    Expert Rev Neurother 10:1699-705. 2010
    ..Clinical practice with respect to non-Alzheimer’s disease indications for ChEIs may vary according to jurisdiction, specifically with regards to whether national guidelines effectively limit off-licence drug use...
  45. doi request reprint Teleneurology: an overview of current status
    A J Larner
    Cognitive Function Clinic, Walton Centre for Neurology and Neurosurgery, Lower Lane, Fazakerley, Liverpool L9 7LJ, UK
    Pract Neurol 11:283-8. 2011
    ..Teleneurology will increasingly impact on all neurologists...
  46. ncbi request reprint Some literary accounts of possible childhood paraplegia and neurorehabilitation
    A J Larner
    Walton Centre for Neurology and Neurosurgery, Fazakerley, Liverpool, UK
    Dev Neurorehabil 12:248-52. 2009
    ..To identify examples of the practice of neurorehabilitation in 19th and early 20th century NOVELS...
  47. ncbi request reprint Monogenic Mendelian disorders in general neurological practice
    A J Larner
    Walton Centre for Neurology and Neurosurgery, Fazakerley, Liverpool, UK
    Int J Clin Pract 62:744-6. 2008
    ..All such patients are probably best referred to specialist clinics where expertise in diagnosis, genetic counselling and testing, and management has been developed...
  48. ncbi request reprint Fornix damage from solitary subependymal giant cell astrocytoma causing postoperative amnesic syndrome
    I Ibrahim
    Neurrehabilitation, Cognitive Function Clinic, Walton Centre for Neurology and Neurosurgery, Fazakerley, Liverpool, UK
    Br J Hosp Med (Lond) 70:478-9. 2009
    ..This article reports the cognitive impairments associated with left fornix damage which became apparent following surgical removal of a solitary subependymal giant cell astrocytoma...
  49. doi request reprint Obstructive sleep apnoea-hypopnoea syndrome presenting in the neurology clinic: a prospective 5-year study
    R Lim
    Walton Centre for Neurology and Neurosurgery, Liverpool, UK
    Int J Clin Pract 62:1886-8. 2008
    ..OSAHS appears to be a rare cause of new symptomatic neurological presentations, although cases may have been overlooked as judgement was based on the index of clinical suspicion alone...
  50. ncbi request reprint Acute aphasia in MS revisited
    A J Larner
    Walton Centre for Neurology and Neurosurgery, Liverpool, UK
    Int MS J 14:76-7. 2007
  51. ncbi request reprint Neuroinhibitory molecules in Alzheimer's disease
    A J Larner
    Cognitive Function Clinic, Walton Centre for Neurology and Neurosurgery, Lower Lane, Liverpool, L9 7LJ, UK
    J Alzheimers Dis 10:75-80. 2006
    ..The molecular species responsible for neuroinhibitory effects in the Alzheimer's disease brain are beginning to be elucidated...
  52. ncbi request reprint Getting it wrong: the clinical misdiagnosis of Alzheimer's disease
    A J Larner
    Cognitive Function Clinic, Walton Centre for Neurology and Neurosurgery, Lower Lane, Fazakerley, Liverpool, UK
    Int J Clin Pract 58:1092-4. 2004
    ..Analysis of diagnostic errors may permit avoidance of similar pitfalls in future...
  53. ncbi request reprint Visual failure caused by vitamin B12 deficiency optic neuropathy
    A J Larner
    Walton Centre for Neurology and Neurosurgery, Lower Lane, Fazakerley, Liverpool, UK
    Int J Clin Pract 58:977-8. 2004
    ..Clues to the possible diagnosis include a history of, or risk factors for, pernicious anaemia, or previous resective gastrointestinal surgery...
  54. doi request reprint Margiad Evans (1909-1958): a history of epilepsy in a creative writer
    A J Larner
    Cognitive Function Clinic, Walton Centre for Neurology and Neurosurgery, Lower Lane, Fazakerley, Liverpool, UK
    Epilepsy Behav 16:596-8. 2009
    ..They also give some insights into the consequences of epilepsy for a creative writer...
  55. ncbi request reprint What role do community pharmacists currently play in the management of headache? A hospital-based perspective
    K K Gahir
    Walton Centre for Neurology and Neurosurgery, Fazakerley, Liverpool, UK
    Int J Clin Pract 58:257-9. 2004
    ..Community pharmacists may represent an underused resource in the management of headaches in primary care, but would require specific training to fulfil such a role...
  56. ncbi request reprint EEG findings in dementia with Lewy bodies causing diagnostic confusion with sporadic Creutzfeldt-Jakob disease
    M Doran
    Cognitive Function Clinic, Walton Centre for Neurology and Neurosurgery, Fazakerley, Liverpool, UK
    Eur J Neurol 11:838-41. 2004
    ..Periodic sharp wave complexes have occasionally been reported in DLB and should not therefore dissuade one from the diagnosis when other clinical and neuropsychological features are consistent with validated diagnostic criteria...
  57. ncbi request reprint Subependymal nodular heterotopia
    A J Larner
    Walton Centre for Neurology and Neurosurgery, Liverpool
    Br J Hosp Med (Lond) 67:382. 2006
  58. ncbi request reprint Single-photon emission computed tomography perfusion imaging in the differential diagnosis of dementia: a retrospective regional audit
    M Doran
    Cognitive Function Clinic, Walton Centre for Neurology and Neurosurgery, Liverpool, UK
    Int J Clin Pract 59:496-500. 2005
    ....
  59. pmc False localising signs
    A J Larner
    Walton Centre for Neorology and Neurosurgery, Lower Lane, Fazkerley, Liverpool L9 7IJ, UK
    J Neurol Neurosurg Psychiatry 74:415-8. 2003
    ..Awareness that signs may be false localising has implications for diagnostic investigation...
  60. doi request reprint Charles Dickens (1812-1870) and epilepsy
    A J Larner
    Cognitive Function Clinic, Walton Centre for Neurology and Neurosurgery, Lower Lane, Fazakerley, Liverpool, UK
    Epilepsy Behav 24:422-5. 2012
    ....
  61. doi request reprint Robert Lawson (?1846-1896)
    A J Larner
    Cognitive Function Clinic, Walton Centre for Neurology and Neurosurgery, Lower Lane, Fazakerley, Liverpool L9 7LJ, UK
    J Neurol 259:792-3. 2012
    ..As Lawson is likely to be an unfamiliar name to most neurologists, and does not appear in the Oxford Dictionary of National Biography, we offer this brief account of his life and work...
  62. ncbi request reprint Diagnosing multiple sclerosis: expect the unexpected
    J Ramtahal
    Walton Centre for Neurology and Neurosurgery, Fazakerley, Liverpool L9 7LJ
    Br J Hosp Med (Lond) 69:230. 2008
  63. ncbi request reprint Pseudostatus epilepticus in pregnancy
    G Peters
    Walton Centre for Neurology and Neurosurgery, Liverpool, UK
    Int J Gynaecol Obstet 97:47. 2007
  64. ncbi request reprint Transient global amnesia in the district general hospital
    A J Larner
    Cognitive Function Clinic, Walton Centre for Neurology and Neurosurgery, Liverpool L9 7LJ, UK
    Int J Clin Pract 61:255-8. 2007
    ..Although rare, TGA is a diagnosis both hospital physicians and general practitioners need to be aware of in order to avoid potential pitfalls. The critical importance of collateral history in reaching the diagnosis is emphasised...
  65. ncbi request reprint Headache induced by dopamine agonists prescribed for prolactinoma: think SUNCT!
    A J Larner
    Walton Centre for Neurology and Neurosurgery, Fazakerley, Liverpool, UK
    Int J Clin Pract 60:360-1. 2006
    ..Endocrinologists treating patients with prolactinoma need to be aware of this syndrome as its pathophysiology and treatment differ from that of other headache syndromes...
  66. ncbi request reprint Delusion of pregnancy in frontotemporal lobar degeneration with motor neurone disease (FTLD/MND)
    A J Larner
    Cognitive Function Clinic, Walton Centre for Neurology and Neurosurgery, Liverpool, UK
    Behav Neurol 19:199-200. 2008
    ..A patient with delusion of pregnancy as an early feature of FTLD/MND is presented to illustrate the need to consider neurodegenerative disease as well as primary psychiatric disorder as the underlying cause of this striking symptom...
  67. ncbi request reprint Obstructive sleep apnoea syndrome presenting in a neurology outpatient clinic
    A J Larner
    Walton Centre for Neurology and Neurosurgery, Liverpool, UK
    Int J Clin Pract 57:150-2. 2003
    ..Since OSAS is associated with increased morbidity and mortality, yet is frequently amenable to treatment, neurologists should be familiar with the heterogeneous presentations of this condition...
  68. ncbi request reprint Missed diagnosis of vitamin B12 deficiency presenting with paraesthetic symptoms
    A J Larner
    Walton Centre for Neurology and Neurosurgery, Liverpool, UK
    Int J Clin Pract 56:377-8. 2002
    ..Two cases in which the diagnosis was initially overlooked are presented, emphasising that the paraesthesia associated with vitamin B12 deficiency may be central (myelopathic) or peripheral (neuropathic) in origin...
  69. ncbi request reprint Antisocial behaviour orders: the need to consider underlying neuropsychiatric disease
    M Doran
    Cognitive Function Clinic, Walton Centre for Neurology and Neurosurgery, Lower Lane, Fazakerley, Liverpool, UK
    Int J Clin Pract 60:861-2. 2006
    ..The need to consider neurological illness as a possible cause of behaviour deemed anti-social is illustrated by a patient eventually diagnosed with neuroacanthocytosis...
  70. doi request reprint Epileptic seizures in AD patients
    A J Larner
    Cognitive Function Clinic, Walton Centre for Neurology and Neurosurgery, Lower Lane, Fazakerley, Liverpool, UK
    Neuromolecular Med 12:71-7. 2010
    ..In summary, epileptic seizures are part of the AD phenotype, and merit further investigation...
  71. ncbi request reprint A possible account of synaesthesia dating from the seventeenth century
    A J Larner
    Cognitive Function Clinic, Walton Centre for Neurology and Neurosurgery, Liverpool, United Kingdom
    J Hist Neurosci 15:245-9. 2006
    ..The details come to us through the physician John Finch, the scientist Robert Boyle, and the author Jonathan Swift. The details in the account suggest the possibility that this may be an early report of colored-touch synaesthesia...
  72. ncbi request reprint Audit of the Addenbrooke's Cognitive Examination (ACE) in clinical practice: 2. longitudinal change
    A J Larner
    Int J Geriatr Psychiatry 21:698-9. 2006
  73. pmc "Who came with you?" A diagnostic observation in patients with memory problems?
    A J Larner
    J Neurol Neurosurg Psychiatry 76:1739. 2005
  74. ncbi request reprint Re: Creutzfeldt-Jacob disease misdiagnosed as dementia with Lewy bodies
    A J Larner
    J Neurol 253:960. 2006
  75. ncbi request reprint Phenotypic similarities causing clinical misdiagnosis of pathologically-confirmed sporadic Creutzfeldt-Jakob disease as dementia with Lewy bodies
    D G Du Plessis
    Greater Manchester Neurosciences Centre, Humphrey Booth Building, Hope Hospital, Salford M6 8HD, UK
    Clin Neurol Neurosurg 110:194-7. 2008
    ..We review the phenotypic overlap between dementia with Lewy bodies and Creutzfeldt-Jakob disease which may cause clinical misdiagnosis...
  76. ncbi request reprint Acute disseminated encephalomyelitis: a riddle wrapped in a mystery inside an enigma
    L John
    Halton General Hospital, Runcorn, Cheshire
    Int J Clin Pract 57:235-7. 2003
    ..Clinical and investigative features which raise the index of suspicion for the diagnosis of ADEM are outlined...
  77. pmc NHS direct for headache
    A J Larner
    J Neurol Neurosurg Psychiatry 74:1698. 2003
  78. pmc Reply to Dr Raux et al.: Molecular diagnosis of autosomal dominant early onset Alzheimer's disease: an update (J Med Genet 2005;42:793-5)
    A J Larner
    J Med Genet 43:e44. 2006
  79. ncbi request reprint NHS direct: growing awareness and use
    A J Larner
    Clin Med 2:275-6. 2002
  80. ncbi request reprint The diagnosis of dementia: diagnostic accuracy of an instrument measuring activities of daily living in a clinic-based population
    P Hancock
    Memory Clinic, 5 Borough Partnership NHS Trust, Brooker Centre, Halton Hospital, Runcorn, UK
    Dement Geriatr Cogn Disord 23:133-9. 2007
    ....
  81. ncbi request reprint MMSE subscores and the diagnosis of dementia with Lewy bodies
    A J Larner
    Int J Geriatr Psychiatry 18:855-6. 2003
  82. ncbi request reprint Adult-onset dementia with prominent frontal lobe dysfunction in X-linked adrenoleukodystrophy with R152C mutation in ABCD1 gene
    A J Larner
    J Neurol 250:1253-4. 2003
  83. ncbi request reprint ENT referrals to the neurology clinic
    A J Abernethy Holland
    Clin Otolaryngol 32:217-8. 2007
  84. ncbi request reprint Multiple mitochondrial DNA deletions in monozygotic twins with OPMD
    M M K Muqit
    Division of Clinical Neurosciences and Psychological Medicine, Imperial College London, UK
    J Neurol Neurosurg Psychiatry 79:68-71. 2008
    ..Previous histological analyses have revealed mitochondrial abnormalities in the muscles of OPMD patients but their significance remains uncertain...
  85. ncbi request reprint Frequency and diagnostic utility of cognitive test instrument use by GPs prior to memory clinic referral
    C A H Fisher
    The Marches Surgery, Leominster, Herefordshire, UK
    Fam Pract 24:495-7. 2007
    ..Previous studies have indicated not only that cases of dementia are missed in primary care but also that many non-demented patients are referred for evaluation to secondary care...
  86. ncbi request reprint Genotype-phenotype correlation in early-onset Alzheimer disease with presenilin 1 gene mutations
    A J Larner
    Arch Neurol 61:801. 2004
  87. pmc Prion disease at a regional neuroscience centre: retrospective audit
    A J Larner
    J Neurol Neurosurg Psychiatry 75:1789-90. 2004
  88. ncbi request reprint Mills syndrome with dementia: broadening the phenotype of FTD/MND
    M Doran
    J Neurol 252:846-7. 2005
  89. pmc Primary headache disorder in the emergency department: perspective from a general neurology outpatient clinic
    K K Gahir
    Pharmacy Department, Princess Royal Hospital, Haywards Heath, West Sussex, UK
    Emerg Med J 23:135-6. 2006
    ..Improved primary care services for headache patients are required to reduce the burden of primary headache disorders seen in emergency departments...
  90. ncbi request reprint An audit of the Addenbrooke's Cognitive Examination (ACE) in clinical practice
    A J Larner
    Int J Geriatr Psychiatry 20:593-4. 2005
  91. doi request reprint Demise of botany in the medical curriculum
    A J Larner
    J Med Biogr 16:1-2. 2008