H K Gleeson

Summary

Affiliation: Christie Hospital
Country: UK

Publications

  1. ncbi request reprint Reassessment of growth hormone status is required at final height in children treated with growth hormone replacement after radiation therapy
    Helena K Gleeson
    Department of Endocrinology, Christie Hospital, Manchester, M20 4BX, United Kingdom
    J Clin Endocrinol Metab 89:662-6. 2004
  2. ncbi request reprint GH responsiveness varies during the menstrual cycle
    Helena K Gleeson
    Department of Endocrinology, Christie Hospital, Wilmslow Road, Withington, Manchester M20 4BX, UK
    Eur J Endocrinol 153:775-9. 2005
  3. ncbi request reprint The impact of cancer therapy on the endocrine system in survivors of childhood brain tumours
    H K Gleeson
    Department of Endocrinology, Christie Hospital, Manchester M20 4BX, UK
    Endocr Relat Cancer 11:589-602. 2004
  4. ncbi request reprint Lipid profiles in untreated severe congenital isolated growth hormone deficiency through the lifespan
    Helena K Gleeson
    Department of Endocrinology, Christie Hospital, Manchester, UK
    Clin Endocrinol (Oxf) 57:89-95. 2002
  5. ncbi request reprint Insulin-like growth factor-I response to a single bolus of growth hormone is increased in obesity
    Helena K Gleeson
    Department of Endocrinology, Christie Hospital, Manchester M20 4BX, UK
    J Clin Endocrinol Metab 90:1061-7. 2005
  6. ncbi request reprint Endocrine complications of neoplastic diseases in children and adolescents
    H K Gleeson
    Department of Endocrinology, Christie Hospital, Wilmslow Road, Withington, Manchester M20 4BX, UK
    Curr Opin Pediatr 13:346-51. 2001
  7. ncbi request reprint GH-deficient survivors of childhood cancer: GH replacement during adult life
    R D Murray
    Department of Endocrinology, Christie Hospital, Manchester, M20 4BX, United Kingdom
    J Clin Endocrinol Metab 87:129-35. 2002
  8. doi request reprint Effect of aromatizable and unaromatizable androgen replacement in hypogonadal men on GH responsiveness
    Helena K Gleeson
    Department of Endocrinology, Christie Hospital, Wilmslow Road, Withington, Manchester, M20 4BX, UK
    Clin Endocrinol (Oxf) 70:109-15. 2009
  9. ncbi request reprint Improvements in final height over 25 years in growth hormone (GH)-deficient childhood survivors of brain tumors receiving GH replacement
    Helena K Gleeson
    Departments of Endocrinology, Pediatric Oncology and Clinical Oncology, Christie Hospital, Manchester, United Kingdom M20 4BX
    J Clin Endocrinol Metab 88:3682-9. 2003
  10. ncbi request reprint Acquired prolactin deficiency indicates severe hypopituitarism in patients with disease of the hypothalamic-pituitary axis
    Annice Mukherjee
    Department of Endocrinology, Christie Hospital, Manchester, UK
    Clin Endocrinol (Oxf) 59:743-8. 2003

Detail Information

Publications13

  1. ncbi request reprint Reassessment of growth hormone status is required at final height in children treated with growth hormone replacement after radiation therapy
    Helena K Gleeson
    Department of Endocrinology, Christie Hospital, Manchester, M20 4BX, United Kingdom
    J Clin Endocrinol Metab 89:662-6. 2004
    ....
  2. ncbi request reprint GH responsiveness varies during the menstrual cycle
    Helena K Gleeson
    Department of Endocrinology, Christie Hospital, Wilmslow Road, Withington, Manchester M20 4BX, UK
    Eur J Endocrinol 153:775-9. 2005
    ..It is not known, however, whether fluctuant levels of endogenous oestrogen modify GH sensitivity. To investigate this further, women were challenged with the IGF-1 generation test at different stages of the menstrual cycle...
  3. ncbi request reprint The impact of cancer therapy on the endocrine system in survivors of childhood brain tumours
    H K Gleeson
    Department of Endocrinology, Christie Hospital, Manchester M20 4BX, UK
    Endocr Relat Cancer 11:589-602. 2004
    ..Gonadal damage secondary to spinal irradiation and adjuvant chemotherapy may have long-term consequences including infertility...
  4. ncbi request reprint Lipid profiles in untreated severe congenital isolated growth hormone deficiency through the lifespan
    Helena K Gleeson
    Department of Endocrinology, Christie Hospital, Manchester, UK
    Clin Endocrinol (Oxf) 57:89-95. 2002
    ..Growth hormone deficiency (GHD) is associated with adverse changes in lipid profile. However, changes in lipids through life in a homogeneous group of GHD subjects have not been defined...
  5. ncbi request reprint Insulin-like growth factor-I response to a single bolus of growth hormone is increased in obesity
    Helena K Gleeson
    Department of Endocrinology, Christie Hospital, Manchester M20 4BX, UK
    J Clin Endocrinol Metab 90:1061-7. 2005
    ..Increment IGF-I is associated positively with GHBP level, which in turn is associated with markers of increasing obesity in men and women. GH responsiveness is increased in obesity...
  6. ncbi request reprint Endocrine complications of neoplastic diseases in children and adolescents
    H K Gleeson
    Department of Endocrinology, Christie Hospital, Wilmslow Road, Withington, Manchester M20 4BX, UK
    Curr Opin Pediatr 13:346-51. 2001
    ....
  7. ncbi request reprint GH-deficient survivors of childhood cancer: GH replacement during adult life
    R D Murray
    Department of Endocrinology, Christie Hospital, Manchester, M20 4BX, United Kingdom
    J Clin Endocrinol Metab 87:129-35. 2002
    ..We propose that, as in patients with hypopituitarism caused by pituitary disease, the main indication for GH replacement in GH-deficient survivors of childhood cancer should be severe impairment of quality of life...
  8. doi request reprint Effect of aromatizable and unaromatizable androgen replacement in hypogonadal men on GH responsiveness
    Helena K Gleeson
    Department of Endocrinology, Christie Hospital, Wilmslow Road, Withington, Manchester, M20 4BX, UK
    Clin Endocrinol (Oxf) 70:109-15. 2009
    ....
  9. ncbi request reprint Improvements in final height over 25 years in growth hormone (GH)-deficient childhood survivors of brain tumors receiving GH replacement
    Helena K Gleeson
    Departments of Endocrinology, Pediatric Oncology and Clinical Oncology, Christie Hospital, Manchester, United Kingdom M20 4BX
    J Clin Endocrinol Metab 88:3682-9. 2003
    ....
  10. ncbi request reprint Acquired prolactin deficiency indicates severe hypopituitarism in patients with disease of the hypothalamic-pituitary axis
    Annice Mukherjee
    Department of Endocrinology, Christie Hospital, Manchester, UK
    Clin Endocrinol (Oxf) 59:743-8. 2003
    ..In this report, adults with disease of the hypothalamic-pituitary axis (HPA) were studied to determine the prevalence of severe acquired prolactin deficiency (APD) and the pathophysiological characteristics associated with it...
  11. ncbi request reprint Late endocrine, metabolic and skeletal sequelae following treatment of childhood cancer
    Helena K Gleeson
    Department of Endocrinology, Christie Hospital, Wilmslow Road, Manchester, Withington, M20 4BX, UK
    Best Pract Res Clin Endocrinol Metab 16:335-48. 2002
    ..In this review we consider the following potential problems: growth hormone deficiency and replacement in adulthood, cardiovascular risk factors, osteopaenia, thyroid and parathyroid dysfunction...
  12. ncbi request reprint The impact of short-term fasting on the dynamics of 24-hour growth hormone (GH) secretion in patients with severe radiation-induced GH deficiency
    Ken H Darzy
    Department of Endocrinology, Christie Hospital, Wilmslow Road, Manchester M20 4BX, United Kingdom
    J Clin Endocrinol Metab 91:987-94. 2006
    ..A sensitive chemiluminescence GH assay was used with cluster analysis...
  13. ncbi request reprint A new missense mutation in the growth hormone-releasing hormone receptor gene in familial isolated GH deficiency
    Mauri Carakushansky
    Divisions of Pediatric Endocrinology and Endocrinology and The Ilyssa Center for Molecular and Cellular Endocrinology, The Johns Hopkins University School of Medicine, Baltimore, Maryland 21287, USA
    Eur J Endocrinol 148:25-30. 2003
    ..We searched for GHRHR mutations in two siblings with IGHD type IB and a history of parental consanguinity...