W John Edmunds
Affiliation: Central Public Health Laboratory
- The 23-valent pneumococcal polysaccharide vaccine. Part II. A cost-effectiveness analysis for invasive disease in the elderly in England and WalesAlessia Melegaro
Modelling and Economics Unit, Health Protection Agency, Communicable Disease Surveillance Centre, London NW9 5EQ, UK
Eur J Epidemiol 19:365-75. 2004....
- Estimating the impact of childhood influenza vaccination programmes in England and WalesEmilia Vynnycky
Modelling and Economics Unit, Health Protection Agency Centre for Infections, 61 Colindale Avenue, Colindale, London NW9 5HT, UK
Vaccine 26:5321-30. 2008..Consistently high levels of vaccination coverage among pre-school children has the potential to bring benefits to both those vaccinated and the community...
- The average cost of measles cases and adverse events following vaccination in industrialised countriesHELENE CARABIN
Department of Infectious Disease Epidemiology, Imperial College Faculty of Medicine, London, UK
BMC Public Health 2:22. 2002..The objective of this study is to develop a model to estimate the average cost per measles case and per adverse event following measles immunisation using the Netherlands (NL), the United Kingdom (UK) and Canada as examples...
- The epidemiology of herpes zoster and potential cost-effectiveness of vaccination in England and WalesW J Edmunds
Department of Economics, City University, Northampton Square, EC1 0HB, London, UK
Vaccine 19:3076-90. 2001....
- The effect of vaccination on the epidemiology of varicella zoster virusW J Edmunds
Immunisation Division, Colindale, London NW9 5EQ, UK
J Infect 44:211-9. 2002..Meanwhile sensitive surveillance of both chickenpox and shingles is essential in countries that have implemented, or are about to implement, varicella vaccination...
- The potential cost-effectiveness of acellular pertussis booster vaccination in England and WalesW John Edmunds
Immunisation Division, PHLS Communicable Disease Surveillance Centre, 61 Collindale Avenue, NW9 5EQ, London, UK
Vaccine 20:1316-30. 2002..Significant uncertainty remains regarding the epidemiology of pertussis and the impact of booster doses. Nevertheless, the introduction of acellular boosters, particularly at 4 years, has the potential to be cost-effective in the UK...
- Measles vaccination in Africa: by how much could routine coverage be improved?W J Edmunds
PHLS Communicable Disease Surveillance Centre, NW9 5EQ, London, UK
Vaccine 20:16-8. 2001..This difference amounts to 3 million African children who will not be vaccinated against measles this year even though they probably have access to immunisation services...
- Modeling future changes to the meningococcal serogroup C conjugate (MCC) vaccine program in England and WalesCaroline L Trotter
Immunisation Department, Health Protection Agency Centre for Infections, London, UK
Hum Vaccin 2:68-73. 2006..The inclusion of a booster dose is likely to improve the impact of the MCC program and reducing the number of doses in infancy will improve cost-effectiveness and create space in the schedule for the addition of other vaccines...
- Deaths from norovirus among the elderly, England and WalesJohn P Harris
Centre for Infections, GEZI, Health Protection Agency, London, UK
Emerg Infect Dis 14:1546-52. 2008..5%-18.5%) of deaths caused by noninfectious intestinal disease were associated with norovirus. An estimated 80 deaths each year in this age group may be associated with norovirus infection...
- The cost effectiveness of opportunistic chlamydia screening in EnglandElisabeth J Adams
Modelling and Economics Unit, Health Protection Agency, 61 Colindale Avenue, Colindale, London NW9 5EQ, UK
Sex Transm Infect 83:267-74; discussion 274-5. 2007..This study aims to estimate the cost effectiveness of (a) the NCSP strategy (annual screening offer to men and women aged under 25 years) and (b) alternative screening strategies...
- Estimating the cost-effectiveness of detecting cases of chronic hepatitis C infection on reception into prisonAndrew J Sutton
Health Protection Agency, Centre for Infections, 61 Colindale Ave, London NW9 5EQ, UK
BMC Public Health 6:170. 2006..The aim of this work is to examine the cost effectiveness of a number of alternative HCV case-finding strategies on prison reception..
- Reassessing the cost-effectiveness of meningococcal serogroup C conjugate (MCC) vaccines using a transmission dynamic modelCaroline L Trotter
Modelling and Economics Unit, Centre for Infections, Health Protection Agency, 61 Colindale Avenue, London, NW95EQ, UK
Med Decis Making 26:38-47. 2006..The latter effect was not accounted for in the previous economic analysis of the MCC program...
- Modelling the impact of a combined varicella and zoster vaccination programme on the epidemiology of varicella zoster virus in EnglandAlbert Jan van Hoek
Immunisation, Hepatitis and Blood Safety Department, Health Protection Agency, London NW9 5EQ, UK
Vaccine 29:2411-20. 2011..At high coverage (90% and 80% coverage) this is unlikely to be the case. These results will be used to inform a cost-effectiveness analysis of combined varicella and zoster vaccination programmes...
- Economic evaluation of infant and adolescent hepatitis B vaccination in the UKM Ruby Siddiqui
Health Protection Agency, Centre for Infections, 61 Colindale Avenue, London NW9 5EQ, UK
Vaccine 29:466-75. 2011....
- Cost-effectiveness of antiviral stockpiling and near-patient testing for potential influenza pandemicM Ruby Siddiqui
Health Protection Agency, London, UK
Emerg Infect Dis 14:267-74. 2008..Stockpiling sufficient AV drugs (but not near-patient tests) to treat all patients with clinical cases would be cost-effective, provided AV drugs are effective at preventing deaths from pandemic influenza...
- Incidence and routes of transmission of hepatitis B virus in England and Wales, 1995-2000: implications for immunisation policySusan Hahne
Health Protection Agency, Communicable Disease Surveillance Centre, Colindale, 61 Colindale Avenue, London NW9 5EQ, UK
J Clin Virol 29:211-20. 2004..The incidence of hepatitis B virus (HBV) infection in the UK is low. Since the infection can have serious sequelae, there is a continuing need to examine its epidemiology so as to inform control measures...
- A metapopulation modelling framework for gonorrhoea and other sexually transmitted infections in heterosexual populationsMark I Chen
Health Protection Agency, Centre for Infections, London NW9 5EQ, UK
J R Soc Interface 6:775-91. 2009..Finally, we extend the model to explain the distribution of other STIs, using chlamydia as an example of a more ubiquitous bacterial STI...
- Different transmission patterns in the early stages of the influenza A(H1N1)v pandemic: a comparative analysis of 12 European countriesStefan Flasche
Centre for Infections, Health Protection Agency, London, UK
Epidemics 3:125-33. 2011..However, much uncertainty remains. With better information on the role of these epidemiological factors, the control of influenza could be improved...
- Modelling cost effectiveness of meningococcal serogroup C conjugate vaccination campaign in England and WalesCaroline L Trotter
Immunisation Division, PHLS Communicable Disease Surveillance Centre, London NW9 5EQ
BMJ 324:809. 2002..To assess the cost effectiveness of a meningococcal serogroup C conjugate vaccination campaign in 0-17 year olds...
- Sero-epidemiological patterns of Epstein-Barr and herpes simplex (HSV-1 and HSV-2) viruses in England and WalesMarianne C Morris
Immunisation Division, Communicable Disease Surveillance Centre, London, United Kingdom
J Med Virol 67:522-7. 2002..Continuing surveillance of these herpes viruses is necessary as the predicted changes could have a significant public health impact, especially in the young adult population...
- Using an online survey of healthcare-seeking behaviour to estimate the magnitude and severity of the 2009 H1N1v influenza epidemic in EnglandEllen Brooks-Pollock
Centre for Mathematical Modelling of Infectious Diseases, London School of Hygiene and Tropical Medicine, London, UK
BMC Infect Dis 11:68. 2011....
- Epidemiology and cost of nosocomial gastroenteritis, Avon, England, 2002-2003Ben A Lopman
Health Protection Agency, London, UK
Emerg Infect Dis 10:1827-34. 2004..Outbreaks were contained faster (7.9 vs. 15.4 days, p = 0.0023) when units were rapidly closed to new admissions (<4 days). Implementing control measures rapidly may be effective in controlling outbreaks...
- Estimating the number of deaths with rotavirus as a cause in England and walesMark Jit
Modelling and Economics Unit, Immunisation Department, Health Protection Agency, London, UK
Hum Vaccin 3:23-6. 2007..The two methods gave estimates of 3.8 and 3.2 rotavirus deaths a year respectively...
- The possible macroeconomic impact on the UK of an influenza pandemicMarcus R Keogh-Brown
Department of Public Health and Policy, London School of Hygiene and Tropical Medicine, London, UK
Health Econ 19:1345-60. 2010..5/2.5%, compared with our severe scenario reductions of 29.5/6%. These results clearly indicate the significance of behavioural change over disease parameters...
- The 23-valent pneumococcal polysaccharide vaccine. Part I. Efficacy of PPV in the elderly: a comparison of meta-analysesAlessia Melegaro
Modelling and Economics Unit, HPA Communicable Disease Surveillance Centre, London, UK
Eur J Epidemiol 19:353-63. 2004..The vaccine has little or no effect against pneumonia (VE = 16% in the general elderly and -20% in HRG)...
- Developing a realistic sexual network model of chlamydia transmission in BritainKatherine M E Turner
Health Protection Agency, Centre for Infections, 61 Colindale Ave, Colindale, London, NW9 5EQ, UK
Theor Biol Med Model 3:3. 2006..Mathematical models provide a theoretical framework for understanding the key epidemiological features of chlamydia: sexual behaviour, health care seeking and transmission dynamics...
- Deaths from chickenpox. Deaths from chickenpox in adults are decreasingMarc Brisson
BMJ 324:609. 2002
- Economic evaluation of vaccination programmes: a consensus statement focusing on viral hepatitisPhilippe Beutels
Viral Hepatitis Prevention Board, Antwerp, Belgium
Pharmacoeconomics 20:1-7. 2002..While targeted hepatitis A vaccination seems economically unattractive, universal hepatitis A vaccination strategies have not yet been sufficiently investigated to draw general conclusions...
- Varicella vaccine and shinglesMarc Brisson
JAMA 287:2211; author reply 2211-2. 2002
- Economic evaluation of human papillomavirus vaccination in the United KingdomMark Jit
Modelling and Economics Unit, Centre for Infections, Health Protection Agency, London NW9 6BT
BMJ 337:a769. 2008..To assess the cost effectiveness of routine vaccination of 12 year old schoolgirls against human papillomavirus infection in the United Kingdom...
- Dynamic models of meningococcal carriage, disease, and the impact of serogroup C conjugate vaccinationCaroline L Trotter
Modelling and Economics Unit, Centre for Infections, Health Protection Agency, London, United Kingdom
Am J Epidemiol 162:89-100. 2005..This model can be used to help predict the potential impact of vaccine strategies both in the United Kingdom and elsewhere...
- The role of economic evaluation in vaccine decision making: focus on meningococcal group C conjugate vaccineRobert Welte
Institute of Health Economics and Health Care Management, GSF National Research Center for Environment and Health, Neuherberg, Germany
Pharmacoeconomics 23:855-74. 2005..In order to improve the international comparability of such studies, firmer national and international modelling guidelines and better adherence to such guidelines seem necessary...
- Using time-use data to parameterize models for the spread of close-contact infectious diseasesEmilio Zagheni
Department of Demography, University of California, Berkeley, 2232 Piedmont Avenue, Berkeley, CA 94720 2120, USA
Am J Epidemiol 168:1082-90. 2008..The availability of time-use data for a large number of countries and their potential to supplement contact surveys make the methods developed extremely valuable and suitable for implementation in several different contexts...
- Future savings from measles eradication in industrialized countriesHELENE CARABIN
Department of Biostatistics and Epidemiology, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma 73104, USA
J Infect Dis 187:S29-35. 2003..These savings are less than previously estimated for the United States, partly because of the assumption that measles vaccines will continue to be delivered in response to possible bioterrorism threats...
- The cost-effectiveness of syndromic management in pharmacies in Lima, PeruElisabeth J Adams
Modelling and Economics Unit, Health Protection Agency, Communicable Disease Surveillance Center, 61 Colindale Avenue, London NW9 5EQ, United Kingdom
Sex Transm Dis 30:379-87. 2003..Many people with sexually transmitted diseases (STDs) in Lima, Peru, seek treatment in pharmacies...
- Cost-effectiveness analyses of human papillomavirus vaccinationAnthony T Newall
School of Public Health, Faculty of Medicine, University of Sydney, Sydney, NSW, Australia
Lancet Infect Dis 7:289-96. 2007..Further refinements to model design and epidemiological variables of (type-specific) HPV disease progression, and expansions on the options for vaccine use, are required for policy making...
- Delaying the international spread of pandemic influenzaBen S Cooper
Statistics, Modelling, and Bioinformatics Department, Centre for Infections, Health Protection Agency, London, United Kingdom
PLoS Med 3:e212. 2006..Moreover, the large increases that have occurred in international air travel might be expected to lead to more rapid global dissemination than in previous pandemics...
- The burden of Herpes Zoster: a prospective population based studyFiona T Scott
Skin Virus Laboratory, Institute for Cell and Molecular Science, 25 29 Ashfield Street, E1 1BB, UK
Vaccine 24:1308-14. 2006..PHN occurred in 13.4% of patients. The average overall cost of HZ in the first 6 months was calculated at pound524 per patient. Medical costs were highest in those aged over 65 and societal costs highest in those aged under 65 years...