A Thapar

Summary

Affiliation: Cardiff University
Country: UK

Publications

  1. ncbi request reprint High loading of polygenic risk for ADHD in children with comorbid aggression
    Marian L Hamshere
    MRC Centre for Neuropsychiatric Genetics and Genomics, Cardiff University School of Medicine, Cardiff, UK
    Am J Psychiatry 170:909-16. 2013
  2. pmc What have we learnt about the causes of ADHD?
    Anita Thapar
    Child and Adolescent Psychiatry Section, Institute of Psychological Medicine and Clinical Neurosciences, Cardiff University School of Medicine, Cardiff, UK
    J Child Psychol Psychiatry 54:3-16. 2013
  3. ncbi request reprint What causes attention deficit hyperactivity disorder?
    Anita Thapar
    Department of Psychological Medicine and Neurology, Cardiff University School of Medicine, Cardiff, UK
    Arch Dis Child 97:260-5. 2012
  4. pmc Rare chromosomal deletions and duplications in attention-deficit hyperactivity disorder: a genome-wide analysis
    Nigel M Williams
    MRC Centre in Neuropsychiatric Genetics and Genomics and Department of Psychological Medicine and Neurology, Cardiff University School of Medicine, Cardiff, UK
    Lancet 376:1401-8. 2010
  5. pmc No evidence of association between Catechol-O-Methyltransferase (COMT) Val158Met genotype and performance on neuropsychological tasks in children with ADHD: a case-control study
    Sophie Mills
    Department of Psychological Medicine, University of Wales College of Medicine, Cardiff, CF14 4XN, UK
    BMC Psychiatry 4:15. 2004
  6. ncbi request reprint The contribution of gene-environment interaction to psychopathology
    Anita Thapar
    Department of Psychological Medicine, School of Medicine, Cardiff University, Heath Park, Cardiff CF14 4XN, UK
    Dev Psychopathol 19:989-1004. 2007
  7. ncbi request reprint Advances in genetic findings on attention deficit hyperactivity disorder
    Anita Thapar
    Department of Psychological Medicine, School of Medicine, Cardiff University, Cardiff, UK
    Psychol Med 37:1681-92. 2007
  8. ncbi request reprint Twin studies in pediatric depression
    Anita Thapar
    Child and Adolescent Psychiatry Section, Department of Psychological Medicine, Cardiff University, Heath Park, Cardiff CF14 4XN, Wales
    Child Adolesc Psychiatr Clin N Am 15:869-81, viii. 2006
  9. ncbi request reprint Refining the attention deficit hyperactivity disorder phenotype for molecular genetic studies
    A Thapar
    Department of Psychological Medicine, Cardiff University, School of Medicine, Heath Park, Cardiff, Wales, UK
    Mol Psychiatry 11:714-20. 2006
  10. ncbi request reprint No evidence of association of two 5HT transporter gene polymorphisms and attention deficit hyperactivity disorder
    Kate Langley
    Department of Psychological Medicine, University of Wales College of Medicine, Cardiff, UK
    Psychiatr Genet 13:107-10. 2003

Detail Information

Publications74

  1. ncbi request reprint High loading of polygenic risk for ADHD in children with comorbid aggression
    Marian L Hamshere
    MRC Centre for Neuropsychiatric Genetics and Genomics, Cardiff University School of Medicine, Cardiff, UK
    Am J Psychiatry 170:909-16. 2013
    ..The findings also highlight the fact that aggression in ADHD indexes genetic as well as clinical severity. ..
  2. pmc What have we learnt about the causes of ADHD?
    Anita Thapar
    Child and Adolescent Psychiatry Section, Institute of Psychological Medicine and Clinical Neurosciences, Cardiff University School of Medicine, Cardiff, UK
    J Child Psychol Psychiatry 54:3-16. 2013
    ..Attention deficit hyperactivity disorder (ADHD) and its possible causes still attract controversy. Genes, pre and perinatal risks, psychosocial factors and environmental toxins have all been considered as potential risk factors...
  3. ncbi request reprint What causes attention deficit hyperactivity disorder?
    Anita Thapar
    Department of Psychological Medicine and Neurology, Cardiff University School of Medicine, Cardiff, UK
    Arch Dis Child 97:260-5. 2012
    ..In this review, the authors consider recent developments in the understanding of risk factors that influence ADHD...
  4. pmc Rare chromosomal deletions and duplications in attention-deficit hyperactivity disorder: a genome-wide analysis
    Nigel M Williams
    MRC Centre in Neuropsychiatric Genetics and Genomics and Department of Psychological Medicine and Neurology, Cardiff University School of Medicine, Cardiff, UK
    Lancet 376:1401-8. 2010
    ..We aimed to establish whether burden of CNVs was increased in ADHD, and to investigate whether identified CNVs were enriched for loci previously identified in autism and schizophrenia...
  5. pmc No evidence of association between Catechol-O-Methyltransferase (COMT) Val158Met genotype and performance on neuropsychological tasks in children with ADHD: a case-control study
    Sophie Mills
    Department of Psychological Medicine, University of Wales College of Medicine, Cardiff, CF14 4XN, UK
    BMC Psychiatry 4:15. 2004
    ..Two studies showed that subjects with the low activity Met allele performed better on the Wisconsin Card Sorting Test (WCST) and another study found an effect on processing speed and attention...
  6. ncbi request reprint The contribution of gene-environment interaction to psychopathology
    Anita Thapar
    Department of Psychological Medicine, School of Medicine, Cardiff University, Heath Park, Cardiff CF14 4XN, UK
    Dev Psychopathol 19:989-1004. 2007
    ..Finally, current and anticipated methodological challenges and implications for future research in this area are considered...
  7. ncbi request reprint Advances in genetic findings on attention deficit hyperactivity disorder
    Anita Thapar
    Department of Psychological Medicine, School of Medicine, Cardiff University, Cardiff, UK
    Psychol Med 37:1681-92. 2007
    ....
  8. ncbi request reprint Twin studies in pediatric depression
    Anita Thapar
    Child and Adolescent Psychiatry Section, Department of Psychological Medicine, Cardiff University, Heath Park, Cardiff CF14 4XN, Wales
    Child Adolesc Psychiatr Clin N Am 15:869-81, viii. 2006
    ....
  9. ncbi request reprint Refining the attention deficit hyperactivity disorder phenotype for molecular genetic studies
    A Thapar
    Department of Psychological Medicine, Cardiff University, School of Medicine, Heath Park, Cardiff, Wales, UK
    Mol Psychiatry 11:714-20. 2006
    ..There is also good empirical support in favour of examining antisocial behaviour in ADHD. Genetic studies of dimensional ADHD are useful for other complementary purposes...
  10. ncbi request reprint No evidence of association of two 5HT transporter gene polymorphisms and attention deficit hyperactivity disorder
    Kate Langley
    Department of Psychological Medicine, University of Wales College of Medicine, Cardiff, UK
    Psychiatr Genet 13:107-10. 2003
    ..In an attempt to replicate these findings, we examined this polymorphism and a variable number tandem repeat in the second intron of 5-HTT for association with ADHD...
  11. pmc Do intrauterine or genetic influences explain the foetal origins of chronic disease? A novel experimental method for disentangling effects
    Anita Thapar
    Department of Psychological Medicine, School of Medicine, Heath Park, Cardiff University, UK
    BMC Med Res Methodol 7:25. 2007
    ..However disentangling these effects in humans poses significant problems for traditional genetic epidemiological research designs...
  12. pmc Prenatal smoking might not cause attention-deficit/hyperactivity disorder: evidence from a novel design
    Anita Thapar
    Department of Psychological Medicine, School of Medicine, Cardiff University, Cardiff, United Kingdom
    Biol Psychiatry 66:722-7. 2009
    ..It is, however, impossible to be certain of adequate control for confounding factors with observational designs. We use a novel "natural experiment" design that separates prenatal environmental from alternative inherited effects...
  13. ncbi request reprint Testing for gene x environment interaction effects in attention deficit hyperactivity disorder and associated antisocial behavior
    K Langley
    Department of Psychological Medicine, School of Medicine, Cardiff University, Heath Park, Cardiff, CF14 4XN, UK
    Am J Med Genet B Neuropsychiatr Genet 147:49-53. 2008
    ..There may be evidence of G x E on associated antisocial behavior in ADHD, but further investigation is needed...
  14. ncbi request reprint A family based study of catechol-O-methyltransferase (COMT) and attention deficit hyperactivity disorder (ADHD)
    D Turic
    Department of Psychological Medicine, University of Wales College of Medicine, Cardiff, United Kingdom
    Am J Med Genet B Neuropsychiatr Genet 133:64-7. 2005
    ..No evidence for association was observed with any single marker or haplotype in a sample of 279 affected children and their parents...
  15. ncbi request reprint Direct analysis of the genes encoding G proteins G alpha T2, G alpha o, G alpha Z in ADHD
    D Turic
    Department of Psychological Medicine, University of Wales College of Medicine, Heath Park, Cardiff, United Kingdom
    Am J Med Genet B Neuropsychiatr Genet 127:68-72. 2004
    ..All were tested for possible association with ADHD using a combination of pooled and individual genotyping. The results of our study do not suggest that polymorphisms in these genes contribute to susceptibility to ADHD...
  16. ncbi request reprint Catechol O-methyltransferase gene variant and birth weight predict early-onset antisocial behavior in children with attention-deficit/hyperactivity disorder
    Anita Thapar
    Department of Psychological Medicine, College of Medicine, School of Psychology, Cardiff University, Heath Park, Cardiff, Wales
    Arch Gen Psychiatry 62:1275-8. 2005
    ..Recent evidence suggests that prefrontal cortical function is influenced by a valine/methionine variant in the catechol O-methyltransferase (COMT) gene...
  17. ncbi request reprint No support for association between the dopamine transporter (DAT1) gene and ADHD
    K Langley
    Department of Psychological Medicine, School of Medicine, Cardiff University, Cardiff, United Kingdom
    Am J Med Genet B Neuropsychiatr Genet 139:7-10. 2005
    ..63 (df 3) P = 0.65). We conclude that the 3' VNTR and three additional promoter variants in DAT1 do not appear to be associated with ADHD, or response to stimulant mediation in our sample...
  18. pmc The links between prenatal stress and offspring development and psychopathology: disentangling environmental and inherited influences
    F Rice
    Department of Psychological Medicine, School of Medicine, Cardiff University, Cardiff, UK
    Psychol Med 40:335-45. 2010
    ..However, associations could arise through factors that influence mothers' characteristics and behaviour during pregnancy which are inherited by offspring...
  19. ncbi request reprint Evidence to suggest biased phenotypes in children with Attention Deficit Hyperactivity Disorder from completely ascertained trios
    A West
    Department of Psychological Medicine, University of Wales College of Medicine, Cardiff, UK
    Mol Psychiatry 7:962-6. 2002
    ....
  20. pmc Steroid sulfatase is a potential modifier of cognition in attention deficit hyperactivity disorder
    E Stergiakouli
    MRC Centre for Neuropsychiatric Genetics and Genomics and Department of Psychological Medicine and Neurology, School of Medicine, Cardiff University, Cardiff, UK
    Genes Brain Behav 10:334-44. 2011
    ..These data suggest that genetic variants affecting STS expression and/or activity could influence the function of brain regions perturbed in ADHD...
  21. pmc A population-based study of anxiety as a precursor for depression in childhood and adolescence
    Frances Rice
    Department of Psychological Medicine, School of Medicine, Cardiff University, Cardiff, UK
    BMC Psychiatry 4:43. 2004
    ..These explanations of the association between early anxiety and later depression were evaluated...
  22. ncbi request reprint Does the definition of ADHD affect heritability?
    A Thapar
    Department of Psychological Medicine, University of Wales College of Medicine, Cardiff, UK
    J Am Acad Child Adolesc Psychiatry 39:1528-36. 2000
    ..A twin study design was used to examine the genetic validity of attention-deficit hyperactivity disorder (ADHD)-related phenotypes...
  23. ncbi request reprint Examining the comorbidity of ADHD-related behaviours and conduct problems using a twin study design
    A Thapar
    Child and Adolescent Psychiatry Section, Department of Psychological Medicine, University of Wales College of Medicine, Cardiff, UK
    Br J Psychiatry 179:224-9. 2001
    ..CONCLUSIONS: Conduct problems and ADHD share a common genetic aetiology; ADHD+CD appears to be a more severe subtype in terms of genetic loading as well as clinical severity...
  24. ncbi request reprint Maternal smoking during pregnancy and attention deficit hyperactivity disorder symptoms in offspring
    Anita Thapar
    Department os Psychological Medicine, University of Wales College of Medicine, Heath Park, Cardiff CF14 4XN, Wales, UK
    Am J Psychiatry 160:1985-9. 2003
    ..The aim of this study was to examine whether smoking during pregnancy is associated with symptoms of attention deficit hyperactivity disorder (ADHD) in offspring and whether these effects are additional to genetic influences...
  25. ncbi request reprint Association of DRD4 in children with ADHD and comorbid conduct problems
    Jane Holmes
    Department of Psychological Medicine, University of Wales College of Medicine, Heath Park, Cardiff, Wales, United Kingdom
    Am J Med Genet 114:150-3. 2002
    ..Further work is needed to examine these phenotype issues...
  26. ncbi request reprint Genes and social skills
    J Scourfield
    University of Wales College of Medicine, Division of Psychological Medicine, Health Park, Cardiff, UK
    Bioessays 19:1125-7. 1997
    ..It may also offer some explanation for why boys are more vulnerable to developmental disorders that affect social behaviour, such as autism...
  27. ncbi request reprint Follow-up of genetic linkage findings on chromosome 16p13: evidence of association of N-methyl-D aspartate glutamate receptor 2A gene polymorphism with ADHD
    D Turic
    Department of Psychological Medicine, University of Wales College of Medicine, Cardiff, UK
    Mol Psychiatry 9:169-73. 2004
    ..We conclude that replication is required and that further work examining for association of GRIN2A polymorphisms with ADHD is warranted...
  28. ncbi request reprint The Cardiff Study of all Wales and North West of England Twins (CaStANET): a longitudinal research program of child and adolescent development
    Marianne B M van den Bree
    Department of Psychological Medicine, Cardiff University, Cardiff, United Kingdom
    Twin Res Hum Genet 10:13-23. 2007
    ....
  29. doi request reprint Psychopathy trait scores in adolescents with childhood ADHD: the contribution of genotypes affecting MAOA, 5HTT and COMT activity
    Tom Fowler
    Department of Psychological Medicine and Neurology, School of Medicine, Cardiff University, Heath Park, Cardiff, UK
    Psychiatr Genet 19:312-9. 2009
    ..The aims of this study were to test whether these gene variants are linked to psychopathy traits in attention-deficit hyperactivity disorder (ADHD)...
  30. ncbi request reprint Relationship between disabling fatigue and depression in children: genetic study
    Tom A Fowler
    Section of Child and Adolescent Psychiatry, Department of Psychological Medicine, Cardiff University, Heath Park, Cardiff, Wales CF14 4XN, UK
    Br J Psychiatry 189:247-53. 2006
    ..Medically unexplained disabling fatigue in young people is familial and frequently associated with depressed mood...
  31. pmc Effects of low birth weight, maternal smoking in pregnancy and social class on the phenotypic manifestation of Attention Deficit Hyperactivity Disorder and associated antisocial behaviour: investigation in a clinical sample
    Kate Langley
    Department of Psychological Medicine, School of Medicine, Cardiff University, Heath Park, Cardiff, UK
    BMC Psychiatry 7:26. 2007
    ..It is possible that these different clinical manifestations of the disorder may arise because of the differing effects of the environmental indicators of environmental risk. We set out to test this hypothesis...
  32. doi request reprint Parent-child hostility and child ADHD symptoms: a genetically sensitive and longitudinal analysis
    Kate J Lifford
    Cardiff University, UK
    J Child Psychol Psychiatry 50:1468-76. 2009
    ..This study aimed to test whether negative parent-child relationships have a risk effect on ADHD symptoms using two complementary designs...
  33. doi request reprint Psychopathy traits in adolescents with childhood attention-deficit hyperactivity disorder
    Tom Fowler
    Department of Psychological Medicine, Cardiff University, Cardiff, UK
    Br J Psychiatry 194:62-7. 2009
    ..Children with attention-deficit hyperactivity disorder (ADHD) are thought to be at higher risk of psychopathy. Early biological and social adversity may contribute to this risk...
  34. ncbi request reprint Association analysis of monoamine oxidase A and attention deficit hyperactivity disorder
    Deborah C Lawson
    Department of Psychologycal Medicine, University of Wales College of Medicine, Cardiff, United Kingdom
    Am J Med Genet B Neuropsychiatr Genet 116:84-9. 2003
    ..0, 95% CI = 1.09, 3.5), and TDT analysis indicated a statistical trend toward association. Our findings highlight the importance of phenotype definition and the need for the MAOA VNTR to be further examined...
  35. ncbi request reprint Assessing the effects of age, sex and shared environment on the genetic aetiology of depression in childhood and adolescence
    Frances Rice
    University of Wales College of Medicine, Cardiff, UK
    J Child Psychol Psychiatry 43:1039-51. 2002
    ..In particular to examine the effects of sex, age, maternal depression and anxiety symptoms and to examine the aetiology of high depression scores...
  36. ncbi request reprint The impact of gestational stress and prenatal growth on emotional problems in offspring: a review
    F Rice
    Department of Psychological Medicine, School of Medicine, Cardiff University, Heath Park, Cardiff, UK
    Acta Psychiatr Scand 115:171-83. 2007
    ..The influence of poor foetal growth and gestational stress in the mother on the risk of emotional problems in offspring was reviewed...
  37. ncbi request reprint Maternal smoking during pregnancy as an environmental risk factor for attention deficit hyperactivity disorder behaviour. A review
    K Langley
    Department of Psychological Medicine, Cardiff University, Heath Park, Cardiff, UK
    Minerva Pediatr 57:359-71. 2005
    ..39, 95% confidence intervals 1.61, 3.52 P<0.001). Maternal smoking during pregnancy is a risk factor for ADHD behaviour and diagnoses, although the mechanisms through which such risks work is unknown...
  38. ncbi request reprint Depressive symptoms in children and adolescents: changing aetiological influences with development
    Jane Scourfield
    Department of Psychological Medicine, University of Wales College of Medicine, Cardiff, UK
    J Child Psychol Psychiatry 44:968-76. 2003
    ..However, the literature is not entirely consistent in this respect and existing longitudinal twin studies have examined changes within adolescence only...
  39. ncbi request reprint Phenotypic variation between parent-offspring trios and non-trios in genetic studies of schizophrenia
    Stanley Zammit
    Department of Psychological Medicine, Cardiff University, Heath Park, Cardiff, CF14 4XN, UK
    J Psychiatr Res 40:622-6. 2006
    ....
  40. ncbi request reprint A pilot twin study of psychological measures of attention deficit hyperactivity disorder
    Jane Holmes
    Child and Adolescent Psychiatry Section, Department of Psychological Medicine, University of Wales College of Medicine, Cardiff, UK
    Behav Genet 32:389-95. 2002
    ..Future work needs to examine whether other neuropsychological measures commonly used in research on ADHD are genetically influenced using larger twin samples...
  41. ncbi request reprint Family conflict interacts with genetic liability in predicting childhood and adolescent depression
    Frances Rice
    Section of Child and Adolescent Psychiatry, Department of Psychological Medicine, School of Medicine, Cardiff University, Cardiff, UK
    J Am Acad Child Adolesc Psychiatry 45:841-8. 2006
    ..Second, to test whether the genetic component of variance in depressive symptoms increases as levels of family conflict increase...
  42. pmc Disentangling prenatal and inherited influences in humans with an experimental design
    Frances Rice
    Department of Psychological Medicine, School of Medicine, Cardiff University, Cardiff CF14 4XN, Wales, United Kingdom
    Proc Natl Acad Sci U S A 106:2464-7. 2009
    ..The origins of behavior and many common complex disorders may begin in early life, therefore this experimental design could pave the way for identifying prenatal factors that affect behavior in future generations...
  43. pmc The effect of birth-weight with genetic susceptibility on depressive symptoms in childhood and adolescence
    Frances Rice
    Dept of Psychological Medicine School of Medicine, Cardiff University, Heath Park, Cardiff, CF14 4XN, UK
    Eur Child Adolesc Psychiatry 15:383-91. 2006
    ....
  44. ncbi request reprint The Link between depression in mothers and offspring: an extended twin analysis
    Frances Rice
    Department of Psychological Medicine, School of Medicine, Cardiff University, Heath Park, Cardiff, CF4 4XN, UK
    Behav Genet 35:565-77. 2005
    ..These findings are interpreted in light of the strengths and weaknesses of the extended twin and other designs...
  45. ncbi request reprint Chromosome 22q11 deletions, velo-cardio-facial syndrome and early-onset psychosis. Molecular genetic study
    D Ivanov
    Neuropsychiatric Genetics Unit, Department of Psychological Medicine, University of Wales College of Medicine, Cardiff, UK
    Br J Psychiatry 183:409-13. 2003
    ..About 30% of patients with VCFS have psychosis, and the rate of these deletions in schizophrenia has been reported to be about 1%. Even higher rates of VCFS deletions have been reported for childhood-onset schizophrenia...
  46. ncbi request reprint Predictors of antisocial behaviour in children with attention deficit hyperactivity disorder
    Anita Thapar
    Dept of Psychological Medicine, Wales College of Medicine Cardiff University, Heath Park, Cardiff, Wales, CF14 4XN, UK
    Eur Child Adolesc Psychiatry 15:118-25. 2006
    ..Antisocial behaviour is an important adverse outcome of ADHD. The aim of this review is to examine what is known about the clinical, genetic and environmental factors that contribute to the link between ADHD and antisocial behaviour...
  47. ncbi request reprint A family based study implicates solute carrier family 1-member 3 (SLC1A3) gene in attention-deficit/hyperactivity disorder
    Darko Turic
    Department of Psychological Medicine, Cardiff University, School of Medicine, Heath Park, Cardiff, United Kingdom
    Biol Psychiatry 57:1461-6. 2005
    ..SLC1A3 is thus both a functional and positional candidate gene for ADHD...
  48. ncbi request reprint Negative life events as an account of age-related differences in the genetic aetiology of depression in childhood and adolescence
    Frances Rice
    Department of Psychological Medicine, University of Wales College of Medicine, Cardiff, UK
    J Child Psychol Psychiatry 44:977-87. 2003
    ..We sought to examine whether this age-related increase in the relative importance of genetic factors is due to an increase in gene-environment correlation specifically involving negative life events...
  49. doi request reprint Adolescent clinical outcomes for young people with attention-deficit hyperactivity disorder
    Kate Langley
    Department of Psychological Medicine and Neurology, School of Medicine, Cardiff University, Heath Park, Cardiff, UK
    Br J Psychiatry 196:235-40. 2010
    ..Attention-deficit hyperactivity disorder (ADHD) is recognised as a common, disabling condition. Little information is available regarding the long-term outcomes for individuals with ADHD in the UK...
  50. doi request reprint Molecular genetic contribution to the developmental course of attention-deficit hyperactivity disorder
    Kate Langley
    Department of Psychological Medicine, School of Medicine, Cardiff University, Heath Park, Cardiff, CF14 4XN, UK
    Eur Child Adolesc Psychiatry 18:26-32. 2009
    ....
  51. ncbi request reprint The genetic aetiology of childhood depression: a review
    Frances Rice
    University of Wales College of Medicine, Heath Park, Cardiff, UK
    J Child Psychol Psychiatry 43:65-79. 2002
    ..We review the evidence for the familiality of major depressive disorder (MDD) and the genetic aetiology of depressive symptoms in children and adolescents...
  52. ncbi request reprint Twins born following fertility treatment: implications for quantitative genetic studies
    Adam Goody
    The School of Psychology, Cardiff University, Cardiff, United Kingdom
    Twin Res Hum Genet 8:337-45. 2005
    ..The differences found between ART and NC twins on group means and twin correlations suggest that researchers should be aware that including ART twins may influence results from twin studies...
  53. ncbi request reprint Genetics of mental retardation
    A S Ahuja
    Department of Psychological Medicine, Cardiff University, Heath Park, Cardiff, United Kingdom
    Indian J Med Sci 59:407-17. 2005
    ..In contrast, where there is no discrete cause, the interplay of genetic and environmental influences remains poorly understood. This article presents a critical review of literature on genetics of mental retardation...
  54. ncbi request reprint The genetics of attention deficit hyperactivity disorder
    Anita Thapar
    Department of Psychological Medicine, Cardiff University, School of Medicine, Heath Park, Cardiff CF14 4XN, UK
    Hum Mol Genet 14:R275-82. 2005
    ..There is increasing research interest in gene-phenotype links, clinical phenotypic markers of heterogeneity and gene--environment interaction, which are likely to be important in the next generation of genetic studies...
  55. ncbi request reprint Mental health and functional outcomes of maternal and adolescent reports of adolescent depressive symptoms
    Frances Rice
    Department of Psychological Medicine, School of Medicine, Cardiff University, Heath Park, Cardiff, Wales
    J Am Acad Child Adolesc Psychiatry 46:1162-70. 2007
    ..The potential influence of mother's own depressed mood on her ratings of adolescent depression and suicidal ideation on adolescent outcome was also tested...
  56. ncbi request reprint Agreement between maternal report and antenatal records for a range of pre and peri-natal factors: the influence of maternal and child characteristics
    Frances Rice
    Department Psychological Medicine, School of Medicine, Cardiff University, Heath Park, Cardiff, CF14 4XN, UK
    Early Hum Dev 83:497-504. 2007
    ..Many studies rely on maternal reports of pre and peri-natal factors. Both maternal and child characteristics may potentially influence the reliability and accuracy of maternal recall. However, this has not been previously examined...
  57. pmc The association between conduct problems and the initiation and progression of marijuana use during adolescence: a genetic analysis across time
    Katherine Shelton
    Department of Psychological Medicine, Cardiff University, Heath Park, Cardiff, CF14 4XN, UK
    Behav Genet 37:314-25. 2007
    ..Multivariate model fitting indicated that conduct problems in childhood and early adolescence made a small but significant contribution to the risk for marijuana use 8 years later...
  58. ncbi request reprint Clinical precursors of adolescent conduct disorder in children with attention-deficit/hyperactivity disorder
    Naureen S Whittinger
    Department of Psychological Medicine, Cardiff University, Cardiff, Wales, UK
    J Am Acad Child Adolesc Psychiatry 46:179-87. 2007
    ..To examine precursors of adolescent conduct disorder (CD) in children with attention-deficit/hyperactivity disorder (ADHD), investigating the significance of childhood oppositional defiant disorder (ODD) and ADHD...
  59. pmc Genetic and environmental influences on the relationship between peer alcohol use and own alcohol use in adolescents
    Tom Fowler
    Department of Psychological Medicine, Cardiff University, Cardiff, UK
    Addiction 102:894-903. 2007
    ..Genetically influenced aspects of adolescent behaviour can play a role in alcohol use and peer affiliation. We explored the correlations between friends' alcohol use and adolescent own use with a genetically sensitive design...
  60. ncbi request reprint Association of the dopamine D4 receptor gene 7-repeat allele with neuropsychological test performance of children with ADHD
    Kate Langley
    Department of Psychological Medicine, University of Wales College of Medicine
    Am J Psychiatry 161:133-8. 2004
    ..In this article the authors examine whether the DRD4 7-repeat allele is associated with performance on a variety of neuropsychological tasks in children with ADHD...
  61. ncbi request reprint The Child Attention-Deficit Hyperactivity Disorder Teacher Telephone Interview (CHATTI): reliability and validity
    Jane Holmes
    Section of Child and Adolescent Psychiatry, Department of Psychological Medicine, University of Wales College of Medicine, Cardiff, UK
    Br J Psychiatry 184:74-8. 2004
    ..Thus, information on children's symptoms in school is usually required. This paper presents the Child ADHD Teacher Telephone Interview (CHATTI), an instrument aimed at systematically obtaining this information...
  62. pmc The definition of disabling fatigue in children and adolescents
    Tom Fowler
    Department of Psychological Medicine, Wales College of Medicine, Cardiff University, UK
    BMC Fam Pract 6:33. 2005
    ....
  63. pmc Associations between maternal older age, family environment and parent and child wellbeing in families using assisted reproductive techniques to conceive
    J Boivin
    School of Psychology, Cardiff University, Park Place, Cardiff, CF10 3AT, Wales, United Kingdom
    Soc Sci Med 68:1948-55. 2009
    ....
  64. pmc Is primary care ready to take on Attention Deficit Hyperactivity Disorder?
    Ajay Thapar
    Department of General Practice, University of Wales College of Medicine and General Practitioner, Taff Riverside Practice, Cardiff, Wales
    BMC Fam Pract 3:7. 2002
    ..Is this role for Primary Care likely to be acceptable and effective?..
  65. pmc Exploring the relationship between genetic and environmental influences on initiation and progression of substance use
    Tom Fowler
    Department of Psychological Medicine, Cardiff University, Cardiff, UK
    Addiction 102:413-22. 2007
    ....
  66. ncbi request reprint Parent-child relationships and ADHD symptoms: a longitudinal analysis
    Kate J Lifford
    School of Psychology, Cardiff University, Tower Building, Park Place, Cardiff, CF10 3AT, UK
    J Abnorm Child Psychol 36:285-96. 2008
    ..Implications for future research focusing on the link between ADHD symptoms and parent-child relationships are discussed...
  67. pmc Attention-deficit hyperactivity disorder
    Ajay K Thapar
    Department of General Practice, University of Wales College of Medicine, Heath Park, Cardiff CF14 4XN
    Br J Gen Pract 53:225-30. 2003
    ..We conclude that, provided the diagnosis of ADHD is made accurately and systematically, there are no good scientific grounds for dismissing the concept of ADHD or for failing to intervene...
  68. ncbi request reprint Gene-environment interplay in attention-deficit hyperactivity disorder and the importance of a developmental perspective
    Anita Thapar
    Br J Psychiatry 190:1-3. 2007
    ..Genes and environmental factors that influence the origins of disorder are not necessarily the same as those that contribute to its course and outcome...
  69. doi request reprint A replicated molecular genetic basis for subtyping antisocial behavior in children with attention-deficit/hyperactivity disorder
    Avshalom Caspi
    Medical Research Council Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, King s College London, London, England
    Arch Gen Psychiatry 65:203-10. 2008
    ..Attention-deficit/hyperactivity disorder (ADHD) is a heterogeneous neurodevelopmental disorder that in some cases is accompanied by antisocial behavior...
  70. ncbi request reprint Characterizing the ADHD phenotype for genetic studies
    Jim Stevenson
    School of Psychology, University of Southampton, Highfield, Southampton SO17 1 BJ, UK
    Dev Sci 8:115-21. 2005
    ..It is suggested that extending such studies beyond cognitive underpinnings to include physiological and metabolic markers might facilitate progress...
  71. ncbi request reprint Prevalence of chronic disabling fatigue in children and adolescents
    Anne Farmer
    MRC Social, Genetic, Developmental Psychiatric Research Centre, Institute of Psychiatry, London, UK
    Br J Psychiatry 184:477-81. 2004
    ..The epidemiology of chronic fatiguing illnesses in young people is poorly understood...
  72. ncbi request reprint No evidence of association between HLA-DRB1 and attention deficit hyperactivity disorder
    Antony Payton
    Centre for Integrated Genomic Medical Research, Stopford Building, Manchester University, Manchester, UK
    Psychiatr Genet 13:183-5. 2003
    ..We attempted to replicate these findings...
  73. pmc Joint analysis of the DRD5 marker concludes association with attention-deficit/hyperactivity disorder confined to the predominantly inattentive and combined subtypes
    Naomi Lowe
    Department of Genetics, Trinity College, Dublin 2, Ireland
    Am J Hum Genet 74:348-56. 2004
    ..The joint analysis showed association with the DRD5 locus (P=.00005; odds ratio 1.24; 95% confidence interval 1.12-1.38). This association appears to be confined to the predominantly inattentive and combined clinical subtypes...