David Stickler

Summary

Affiliation: Cardiff University
Country: UK

Publications

  1. ncbi request reprint Strategies for the control of catheter encrustation
    D J Stickler
    Cardiff School of Biosciences, Cardiff University, Park Place, Cardiff CF10 3TL, Wales, UK
    Int J Antimicrob Agents 19:499-506. 2002
  2. ncbi request reprint Factors affecting crystal precipitation from urine in individuals with long-term urinary catheters colonized with urease-positive bacterial species
    Sunil Mathur
    BioMed Centre, Bristol Urological Institute, Southmead Hospital, Bristol, BS10 5NB, UK
    Urol Res 34:173-7. 2006
  3. ncbi request reprint Species interactions in mixed-community crystalline biofilms on urinary catheters
    Sarah M Macleod
    Cardiff School of Biosciences, Cardiff University, Cardiff, UK
    J Med Microbiol 56:1549-57. 2007
  4. doi request reprint Some observations on the migration of Proteus mirabilis and other urinary tract pathogens over foley catheters
    Gareth J Williams
    Welsh School of Pharmacy, Cardiff University, Cardiff, Wales, UK
    Infect Control Hosp Epidemiol 29:443-5. 2008
  5. doi request reprint Observations on the development of the crystalline bacterial biofilms that encrust and block Foley catheters
    D J Stickler
    Cardiff School of Biosciences, Cardiff University, Cardiff, UK
    J Hosp Infect 69:350-60. 2008
  6. doi request reprint Bacterial biofilms in patients with indwelling urinary catheters
    David J Stickler
    Cardiff School of Biosciences, Main Building, Cardiff University, Museum Avenue, Cardiff CF103TL, UK
    Nat Clin Pract Urol 5:598-608. 2008
  7. pmc Reduced Susceptibility of Proteus mirabilis to triclosan
    David J Stickler
    Cardiff School of Biosciences, Cardiff University, Cardiff CF10 3TL, Wales, United Kingdom
    Antimicrob Agents Chemother 52:991-4. 2008
  8. ncbi request reprint A clinical assessment of the performance of a sensor to detect crystalline biofilm formation on indwelling bladder catheters
    David J Stickler
    Cardiff School of Dentistry, Cardiff University, Cardiff, Wales, UK
    BJU Int 98:1244-9. 2006
  9. ncbi request reprint Observations on the adherence of Proteus mirabilis onto polymer surfaces
    D J Stickler
    Cardiff School of Biosciences, Cardiff University, Cardiff, Wales, UK
    J Appl Microbiol 100:1028-33. 2006
  10. pmc A sensor to detect the early stages in the development of crystalline Proteus mirabilis biofilm on indwelling bladder catheters
    D J Stickler
    Cardiff School of Biosciences, Cardiff University, Cardiff CF10 3TL, Wales, United Kingdom
    J Clin Microbiol 44:1540-2. 2006

Collaborators

Detail Information

Publications18

  1. ncbi request reprint Strategies for the control of catheter encrustation
    D J Stickler
    Cardiff School of Biosciences, Cardiff University, Park Place, Cardiff CF10 3TL, Wales, UK
    Int J Antimicrob Agents 19:499-506. 2002
    ..The main organisms colonising the stents were enterococci and coagulase-negative staphylococci. These results suggest that the mechanisms of catheter and stent encrustation may be different and require different strategies for control...
  2. ncbi request reprint Factors affecting crystal precipitation from urine in individuals with long-term urinary catheters colonized with urease-positive bacterial species
    Sunil Mathur
    BioMed Centre, Bristol Urological Institute, Southmead Hospital, Bristol, BS10 5NB, UK
    Urol Res 34:173-7. 2006
    ..Reducing the rate of catheter encrustation could be achieved by lowering the urinary concentration of calcium and magnesium, which may only require catheter users to increase their fluid intake...
  3. ncbi request reprint Species interactions in mixed-community crystalline biofilms on urinary catheters
    Sarah M Macleod
    Cardiff School of Biosciences, Cardiff University, Cardiff, UK
    J Med Microbiol 56:1549-57. 2007
    ..mirabilis and some of the other urinary tract organisms, the effects are temporary and whatever the pre-existing urinary microbiota, infection with P. mirabilis is thus likely to lead to catheter encrustation and blockage...
  4. doi request reprint Some observations on the migration of Proteus mirabilis and other urinary tract pathogens over foley catheters
    Gareth J Williams
    Welsh School of Pharmacy, Cardiff University, Cardiff, Wales, UK
    Infect Control Hosp Epidemiol 29:443-5. 2008
    ..P. aeruginosa migrated over both triclosan-impregnated and nitrofurazone-impregnated catheters, but these antibacterials inhibited the migration of P. mirabilis...
  5. doi request reprint Observations on the development of the crystalline bacterial biofilms that encrust and block Foley catheters
    D J Stickler
    Cardiff School of Biosciences, Cardiff University, Cardiff, UK
    J Hosp Infect 69:350-60. 2008
    ..If antimicrobials are to be incorporated into catheters to prevent encrustation, it is important that they diffuse into the urine and prevent the rise in pH that triggers crystal formation...
  6. doi request reprint Bacterial biofilms in patients with indwelling urinary catheters
    David J Stickler
    Cardiff School of Biosciences, Main Building, Cardiff University, Museum Avenue, Cardiff CF103TL, UK
    Nat Clin Pract Urol 5:598-608. 2008
    ..Infection with P. mirabilis exposes the many faults of currently available catheters, and plenty of scope exists for improvement in both their design and production; manufacturers should take up the challenge to improve patient outcomes...
  7. pmc Reduced Susceptibility of Proteus mirabilis to triclosan
    David J Stickler
    Cardiff School of Biosciences, Cardiff University, Cardiff CF10 3TL, Wales, United Kingdom
    Antimicrob Agents Chemother 52:991-4. 2008
    ..mirabilis strains with reduced susceptibility to triclosan. The emergence of these strains could undermine the ability of the triclosan strategy to control catheter encrustation...
  8. ncbi request reprint A clinical assessment of the performance of a sensor to detect crystalline biofilm formation on indwelling bladder catheters
    David J Stickler
    Cardiff School of Dentistry, Cardiff University, Cardiff, Wales, UK
    BJU Int 98:1244-9. 2006
    ....
  9. ncbi request reprint Observations on the adherence of Proteus mirabilis onto polymer surfaces
    D J Stickler
    Cardiff School of Biosciences, Cardiff University, Cardiff, Wales, UK
    J Appl Microbiol 100:1028-33. 2006
    ..The aim of this work is to identify a surface-coating for catheters that is not vulnerable to colonization by Pr. mirabilis...
  10. pmc A sensor to detect the early stages in the development of crystalline Proteus mirabilis biofilm on indwelling bladder catheters
    D J Stickler
    Cardiff School of Biosciences, Cardiff University, Cardiff CF10 3TL, Wales, United Kingdom
    J Clin Microbiol 44:1540-2. 2006
    ..In laboratory models of colonization by Proteus mirabilis, the sensor signaled encrustation at an average time of 43 h before catheters were blocked with crystalline biofilm...
  11. ncbi request reprint Modulation of crystalline Proteus mirabilis biofilm development on urinary catheters
    David J Stickler
    Cardiff School of Biosciences, Cardiff University, Cardiff CF10 3TL, UK
    J Med Microbiol 55:489-94. 2006
    ..These observations should encourage a clinical trial to examine the effect of increasing a patient's fluid intake with citrate-containing drinks on the encrustation and blockage of catheters...
  12. doi request reprint The encrustation and blockage of long-term indwelling bladder catheters: a way forward in prevention and control
    D J Stickler
    Cardiff School of Biosciences, Cardiff University, Wales, UK
    Spinal Cord 48:784-90. 2010
    ....
  13. ncbi request reprint Control of encrustation and blockage of Foley catheters
    D J Stickler
    Cardiff School of Biosciences, Cardiff University, Cardiff CF10 3TL, Wales, UK
    Lancet 361:1435-7. 2003
    ..Our observations suggest a way to control a common complication in patients with long-term indwelling bladder catheters...
  14. ncbi request reprint Why are Foley catheters so vulnerable to encrustation and blockage by crystalline bacterial biofilm?
    David Stickler
    Cardiff School of Biosciences, Cardiff University, Cardiff CF10 3TL, UK
    Urol Res 31:306-11. 2003
    ..There is a need to improve catheter design and manufacturing procedures for the eye-holes if the problems associated with the current devices are to be reduced...
  15. doi request reprint Effect of triclosan on the formation of crystalline biofilms by mixed communities of urinary tract pathogens on urinary catheters
    Gareth J Williams
    Cardiff School of Biosciences, Cardiff University, Cardiff CF10 3TL, UK
    J Med Microbiol 57:1135-40. 2008
    ..The results indicate that the triclosan strategy should be limited to the treatment of patients who are infected with Proteus mirabilis...
  16. pmc Ultrastructure of Proteus mirabilis swarmer cell rafts and role of swarming in catheter-associated urinary tract infection
    Brian V Jones
    Cardiff School of Biosciences, Cardiff University, Main Bldg, Rm 1 53, Cardiff, Wales, United Kingdom CF10 3TL
    Infect Immun 72:3941-50. 2004
    ..In addition, the highly organized structure of multicellular rafts enables P. mirabilis to initiate C-UTI by migration over catheter surfaces from the urethral meatus into the bladder...
  17. ncbi request reprint An electrified catheter to resist encrustation by Proteus mirabilis biofilm
    Aniruddha Chakravarti
    Department of Urology, Walsgrave Hospital, University Hospital of Coventry, United Kingdom
    J Urol 174:1129-32. 2005
    ..We investigated the effect of iontophoresis produced by passing an electric current through silver electrodes attached to catheters on catheter encrustation by crystalline Proteus mirabilis biofilm...
  18. ncbi request reprint Prospective study of individuals with long-term urinary catheters colonized with Proteus species
    Sunil Mathur
    Bristol Urological Institute, Southmead Hospital, Bristol, UK
    BJU Int 97:121-8. 2006
    ..To characterize the variability in the times catheters take to block with encrustation in patients who have Proteus in their urinary flora, and to identify factors responsible for modulating the rate of catheter encrustation and blockage...