Kevin Murphy

Summary

Affiliation: Cardiff University
Country: UK

Publications

  1. pmc The effects of altered intrathoracic pressure on resting cerebral blood flow and its response to visual stimulation
    Anja Hayen
    Nuffield Division of Anaesthetics and Oxford Centre for Functional Magnetic Resonance Imaging of the Brain FMRIB, Nuffield Department of Clinical Neurosciences, John Radcliffe Hospital, University of Oxford, Oxford, OX3 9DU, UK Electronic address
    Neuroimage 66:479-88. 2013
  2. pmc Resting-state fMRI confounds and cleanup
    Kevin Murphy
    Cardiff University Brain Research Imaging Centre, School of Psychology, Cardiff University, Cardiff, CF10 3AT, UK
    Neuroimage 80:349-59. 2013
  3. doi request reprint Robustly measuring vascular reactivity differences with breath-hold: normalising stimulus-evoked and resting state BOLD fMRI data
    Kevin Murphy
    Cardiff University Brain Research Imaging Centre CUBRIC, School of Psychology, Cardiff University, Cardiff, UK
    Neuroimage 54:369-79. 2011
  4. pmc In vivo assessment of human brainstem cerebrovascular function: a multi-inversion time pulsed arterial spin labelling study
    Esther A H Warnert
    Cardiff University Brain Research and Imaging Centre CUBRIC, School of Psychology, Cardiff University, Cardiff, UK
    J Cereb Blood Flow Metab 34:956-63. 2014
  5. pmc Cerebral blood flow response to acute hypoxic hypoxia
    Ashley D Harris
    CUBRIC, School of Psychology, Cardiff University, Cardiff, UK
    NMR Biomed 26:1844-52. 2013
  6. pmc The thalamus and brainstem act as key hubs in alterations of human brain network connectivity induced by mild propofol sedation
    Tommaso Gili
    Cardiff University Brain Research Imaging Centre, School of Psychology, Cardiff University, Cardiff, CF10 3AT, United Kingdom
    J Neurosci 33:4024-31. 2013
  7. pmc Reliable quantification of BOLD fMRI cerebrovascular reactivity despite poor breath-hold performance
    Molly G Bright
    Cardiff University Brain Research Imaging Centre CUBRIC, School of Psychology, Cardiff University, CF10 3AT Cardiff, UK Electronic address
    Neuroimage 83:559-68. 2013
  8. doi request reprint Pulsed arterial spin labeling perfusion imaging at 3 T: estimating the number of subjects required in common designs of clinical trials
    Kevin Murphy
    Cardiff University Brain Research Imaging Centre CUBRIC, School of Psychology, Cardiff University, CF10 3AT Cardiff, UK
    Magn Reson Imaging 29:1382-9. 2011
  9. pmc Separating neural and vascular effects of caffeine using simultaneous EEG-FMRI: differential effects of caffeine on cognitive and sensorimotor brain responses
    Ana Diukova
    Cardiff University Brain Research Imaging Centre, School of Psychology, Cardiff University, Cardiff, UK
    Neuroimage 62:239-49. 2012
  10. doi request reprint The Relationship between Fearfulness, GABA+, and Fear-Related BOLD Responses in the Insula
    Ilona Lipp
    Cardiff University Brain Research Imaging Centre CUBRIC, School of Psychology, Cardiff University, Cardiff, United Kingdom MRC Centre for Neuropsychiatric Genetics and Genomics, Institute of Psychological Medicine and Clinical Neurosciences, Cardiff University, Cardiff, United Kingdom
    PLoS ONE 10:e0120101. 2015

Collaborators

Detail Information

Publications16

  1. pmc The effects of altered intrathoracic pressure on resting cerebral blood flow and its response to visual stimulation
    Anja Hayen
    Nuffield Division of Anaesthetics and Oxford Centre for Functional Magnetic Resonance Imaging of the Brain FMRIB, Nuffield Department of Clinical Neurosciences, John Radcliffe Hospital, University of Oxford, Oxford, OX3 9DU, UK Electronic address
    Neuroimage 66:479-88. 2013
    ....
  2. pmc Resting-state fMRI confounds and cleanup
    Kevin Murphy
    Cardiff University Brain Research Imaging Centre, School of Psychology, Cardiff University, Cardiff, CF10 3AT, UK
    Neuroimage 80:349-59. 2013
    ..For successful interpretation of resting-state fMRI comparisons and results, noise cleanup is an often over-looked but essential step in the analysis pipeline...
  3. doi request reprint Robustly measuring vascular reactivity differences with breath-hold: normalising stimulus-evoked and resting state BOLD fMRI data
    Kevin Murphy
    Cardiff University Brain Research Imaging Centre CUBRIC, School of Psychology, Cardiff University, Cardiff, UK
    Neuroimage 54:369-79. 2011
    ..This demonstrates that individual end-tidal CO(2) increases to breath-hold should be accounted for to provide an accurate measure of vascular reactivity resulting in more statistically active voxels in group level analyses...
  4. pmc In vivo assessment of human brainstem cerebrovascular function: a multi-inversion time pulsed arterial spin labelling study
    Esther A H Warnert
    Cardiff University Brain Research and Imaging Centre CUBRIC, School of Psychology, Cardiff University, Cardiff, UK
    J Cereb Blood Flow Metab 34:956-63. 2014
    ..Multi-inversion time pulsed ASL in combination with a two-compartment signal model can be used to assess BS perfusion and CVR. ..
  5. pmc Cerebral blood flow response to acute hypoxic hypoxia
    Ashley D Harris
    CUBRIC, School of Psychology, Cardiff University, Cardiff, UK
    NMR Biomed 26:1844-52. 2013
    ..CBF and R2* reactivity to hypoxia differed between subjects, but only R2* reactivity to hypoxia differed significantly between brain regions...
  6. pmc The thalamus and brainstem act as key hubs in alterations of human brain network connectivity induced by mild propofol sedation
    Tommaso Gili
    Cardiff University Brain Research Imaging Centre, School of Psychology, Cardiff University, Cardiff, CF10 3AT, United Kingdom
    J Neurosci 33:4024-31. 2013
    ....
  7. pmc Reliable quantification of BOLD fMRI cerebrovascular reactivity despite poor breath-hold performance
    Molly G Bright
    Cardiff University Brain Research Imaging Centre CUBRIC, School of Psychology, Cardiff University, CF10 3AT Cardiff, UK Electronic address
    Neuroimage 83:559-68. 2013
    ..We conclude that the incorporation of end-tidal CO2 monitoring into scanning enables robust, repeatable measurement of CVR that makes breath-hold challenges suitable for routine clinical practice...
  8. doi request reprint Pulsed arterial spin labeling perfusion imaging at 3 T: estimating the number of subjects required in common designs of clinical trials
    Kevin Murphy
    Cardiff University Brain Research Imaging Centre CUBRIC, School of Psychology, Cardiff University, CF10 3AT Cardiff, UK
    Magn Reson Imaging 29:1382-9. 2011
    ..Such sample sizes make feasible the use of such CBF measurements in clinical trials of drugs...
  9. pmc Separating neural and vascular effects of caffeine using simultaneous EEG-FMRI: differential effects of caffeine on cognitive and sensorimotor brain responses
    Ana Diukova
    Cardiff University Brain Research Imaging Centre, School of Psychology, Cardiff University, Cardiff, UK
    Neuroimage 62:239-49. 2012
    ..The combined use of EEG-FMRI is a promising methodology for investigating alterations in brain function in drug and disease studies where neurovascular coupling may be altered on a regional basis...
  10. doi request reprint The Relationship between Fearfulness, GABA+, and Fear-Related BOLD Responses in the Insula
    Ilona Lipp
    Cardiff University Brain Research Imaging Centre CUBRIC, School of Psychology, Cardiff University, Cardiff, United Kingdom MRC Centre for Neuropsychiatric Genetics and Genomics, Institute of Psychological Medicine and Clinical Neurosciences, Cardiff University, Cardiff, United Kingdom
    PLoS ONE 10:e0120101. 2015
    ..Our findings indicate that low insular GABA concentration is not a predisposition for fearfulness, and that several factors influence whether a correlation between GABA and BOLD can be found. ..
  11. pmc Removing motion and physiological artifacts from intrinsic BOLD fluctuations using short echo data
    Molly G Bright
    Cardiff University Brain Research Imaging Centre, School of Psychology, Cardiff University, CF10 3AT Cardiff, UK
    Neuroimage 64:526-37. 2013
    ..Results suggest that short TE correction more accurately differentiates artifactual correlations from the correlations of interest in conditions of amplified noise...
  12. pmc Temporal dynamics of lactate concentration in the human brain during acute inspiratory hypoxia
    Ashley D Harris
    Cardiff University Brain Imaging Research Centre, School of Psychology, Cardiff University, Cardiff, UK
    J Magn Reson Imaging 37:739-45. 2013
    ..To demonstrate the feasibility of measuring the temporal dynamics of cerebral lactate concentration and examine these dynamics in human subjects using magnetic resonance spectroscopy (MRS) during hypoxia...
  13. doi request reprint Noninvasive assessment of arterial compliance of human cerebral arteries with short inversion time arterial spin labeling
    Esther Ah Warnert
    Cardiff University Brain Research and Imaging Centre CUBRIC, School of Psychology, Cardiff University, Cardiff, UK
    J Cereb Blood Flow Metab 35:461-8. 2015
    ..56%±0.2%, 0.50%±0.3%, 0.4%±0.2%, 1.1%±0.5%, and 1.1%±0.3% per mm Hg, respectively. The current experiment has shown the feasibility of measuring AC of cerebral arteries with short inversion time PASL. ..
  14. pmc Measurement of OEF and absolute CMRO2: MRI-based methods using interleaved and combined hypercapnia and hyperoxia
    Richard G Wise
    Cardiff University Brain Research Imaging Centre CUBRIC, School of Psychology, Cardiff University, Park Place, Cardiff CF10 3AT, UK Electronic address
    Neuroimage 83:135-47. 2013
    ....
  15. pmc Ventral striatum activity in response to reward: differences between bipolar I and II disorders
    Xavier Caseras
    MRC Center for Neuropsychiatric Genetics and Genomics, Institute of Psychological Medicine and Clinical Neurosciences, Cardiff University, UK
    Am J Psychiatry 170:533-41. 2013
    ....
  16. pmc Early anti-correlated BOLD signal changes of physiologic origin
    Molly G Bright
    Advanced MRI Section, LFMI, NINDS, National Institutes of Health, Bethesda, MD, USA Cardiff University Brain Research Imaging Centre CUBRIC, School of Psychology, Cardiff University, Cardiff, UK Electronic address
    Neuroimage 87:287-96. 2014
    ..Thus, the addition of a physiological challenge to fMRI experiments can help identify which negative BOLD signals are passive physiological anti-correlations and which may have a putative neuronal origin. ..