J E Morgan

Summary

Affiliation: Cardiff University
Country: UK

Publications

  1. ncbi Retina ganglion cell degeneration in glaucoma: an opportunity missed? A review
    James E Morgan
    School of Optometry and Vision Sciences, Cardiff University, Cardiff, UK
    Clin Experiment Ophthalmol 40:364-8. 2012
  2. ncbi The accuracy of the inferior>superior>nasal>temporal neuroretinal rim area rule for diagnosing glaucomatous optic disc damage
    James E Morgan
    Department of Ophthalmology, University Hospital of Wales, Cardiff, United Kingdom
    Ophthalmology 119:723-30. 2012
  3. ncbi Digital imaging of the optic nerve head: monoscopic and stereoscopic analysis
    J E Morgan
    Department of Ophthalmology, University Hospital of Wales, Heath Park, Cardiff CF4 4XW, UK
    Br J Ophthalmol 89:879-84. 2005
  4. ncbi Discrimination of glaucomatous optic neuropathy by digital stereoscopic analysis
    J E Morgan
    Department of Ophthalmology, University Hospital of Wales, Cardiff, United Kingdom
    Ophthalmology 112:855-62. 2005
  5. ncbi Circulation and axonal transport in the optic nerve
    J E Morgan
    Department of Ophthalmology, University Hospital of Wales, Heath Park, Cardiff, UK
    Eye (Lond) 18:1089-95. 2004
  6. ncbi Scanning laser polarimetry of the normal human retinal nerve fiber layer: a quantitative analysis
    J E Morgan
    Department of Ophthalmology, University of Wales College of Medicine, Cardiff, United Kingdom
    Am J Ophthalmol 129:76-82. 2000
  7. ncbi Retinal ganglion cell shrinkage in glaucoma
    J E Morgan
    Department of Ophthalmology, University Hospital of Wales, Heath Park, Cardiff, United Kingdom
    J Glaucoma 11:365-70. 2002
  8. ncbi Remodelling the filtration bleb
    J E Morgan
    Department of Ophthalmology, University Hospital of Wales, Heath Park, Cardiff CF4 4XW, UK
    Br J Ophthalmol 86:872-5. 2002
  9. ncbi Optic nerve head structure in glaucoma: astrocytes as mediators of axonal damage
    J E Morgan
    Department of Ophthalmology, University of Wales College of Medicine, Cardiff, UK
    Eye (Lond) 14:437-44. 2000
  10. ncbi Transretinal degeneration in ageing human retina: a multiphoton microscopy analysis
    Y Lei
    Optometry and Vision Sciences, Cardiff University, Cardiff, UK
    Br J Ophthalmol 95:727-30. 2011

Collaborators

Detail Information

Publications27

  1. ncbi Retina ganglion cell degeneration in glaucoma: an opportunity missed? A review
    James E Morgan
    School of Optometry and Vision Sciences, Cardiff University, Cardiff, UK
    Clin Experiment Ophthalmol 40:364-8. 2012
    ..If substantial numbers of degenerating retinal ganglion cells are present in glaucoma, they could present an ideal target for the recovery of vision...
  2. ncbi The accuracy of the inferior>superior>nasal>temporal neuroretinal rim area rule for diagnosing glaucomatous optic disc damage
    James E Morgan
    Department of Ophthalmology, University Hospital of Wales, Cardiff, United Kingdom
    Ophthalmology 119:723-30. 2012
    ....
  3. ncbi Digital imaging of the optic nerve head: monoscopic and stereoscopic analysis
    J E Morgan
    Department of Ophthalmology, University Hospital of Wales, Heath Park, Cardiff CF4 4XW, UK
    Br J Ophthalmol 89:879-84. 2005
    ..To compare monoscopic and stereoscopic assessment of the optic disc using novel software for the digital stereoscopic analysis of optic disc stereopairs...
  4. ncbi Discrimination of glaucomatous optic neuropathy by digital stereoscopic analysis
    J E Morgan
    Department of Ophthalmology, University Hospital of Wales, Cardiff, United Kingdom
    Ophthalmology 112:855-62. 2005
    ..To evaluate the diagnostic power of a novel digital stereoscopic imaging system in the diagnosis of glaucomatous optic neuropathy...
  5. ncbi Circulation and axonal transport in the optic nerve
    J E Morgan
    Department of Ophthalmology, University Hospital of Wales, Heath Park, Cardiff, UK
    Eye (Lond) 18:1089-95. 2004
    ..Considerable work has been undertaken in this area to advance our understanding on the pathophysiology of axon damage and to develop new strategies for the prevention of retinal ganglion cell death...
  6. ncbi Scanning laser polarimetry of the normal human retinal nerve fiber layer: a quantitative analysis
    J E Morgan
    Department of Ophthalmology, University of Wales College of Medicine, Cardiff, United Kingdom
    Am J Ophthalmol 129:76-82. 2000
    ....
  7. ncbi Retinal ganglion cell shrinkage in glaucoma
    J E Morgan
    Department of Ophthalmology, University Hospital of Wales, Heath Park, Cardiff, United Kingdom
    J Glaucoma 11:365-70. 2002
    ..It is also likely that widespread changes in the retinal ganglion cell population precede cell death, which will affect the physiologic behavior of these cells...
  8. ncbi Remodelling the filtration bleb
    J E Morgan
    Department of Ophthalmology, University Hospital of Wales, Heath Park, Cardiff CF4 4XW, UK
    Br J Ophthalmol 86:872-5. 2002
    ..To report remodelling of enlarged dysmorphic filtration blebs with conjunctival compression sutures and autologous blood injection...
  9. ncbi Optic nerve head structure in glaucoma: astrocytes as mediators of axonal damage
    J E Morgan
    Department of Ophthalmology, University of Wales College of Medicine, Cardiff, UK
    Eye (Lond) 14:437-44. 2000
    ....
  10. ncbi Transretinal degeneration in ageing human retina: a multiphoton microscopy analysis
    Y Lei
    Optometry and Vision Sciences, Cardiff University, Cardiff, UK
    Br J Ophthalmol 95:727-30. 2011
    ..However, the degree to which this results in transretinal degeneration is unclear. To address this, the authors used multiphoton microscopy to quantify retinal degeneration in post-mortem human eyes of two age groups...
  11. ncbi Evaluation of the high specificity Screening Program (C-20-1) of the Frequency Doubling Technology (FDT) perimeter in clinical practice
    R V North
    Cardiff School of Optometry and Vision Sciences, Cardiff University, Cardiff, UK
    Eye (Lond) 20:681-7. 2006
    ..To compare the efficacy of the high specificity Frequency Doubling Technology (FDT) Perimeter Screening Program (C-20-1) to standard threshold automated perimetry in the diagnosis of open-angle glaucoma...
  12. ncbi The effects of astigmatism and working distance on optic nerve head images using a Heidelberg Retina Tomograph scanning laser ophthalmoscope
    N J Sheen
    Department of Optometry and Vision Sciences, Cardiff University, Cardiff, United Kingdom
    Am J Ophthalmol 131:716-21. 2001
    ..50 DC) or working distance. The algorithm used by the Heidelberg Retina Tomograph to generate topographic maps is sufficiently robust that astigmatism up to 2.50 DC does not require correction...
  13. ncbi Acutance, an objective measure of retinal nerve fibre image clarity
    Y F Choong
    Retinal Imaging Laboratory, Department of Optometry and Vision Sciences, Cardiff University, PO Box 905, Cardiff CF10, United Kingdom
    Br J Ophthalmol 87:322-6. 2003
    ..Objective measures of image quality should help in the discrimination of diffuse retinal nerve fibre loss from image blur in patients with diffuse glaucomatous damage...
  14. ncbi Topography of neuron loss in the retinal ganglion cell layer in human glaucoma
    Y Lei
    School of Optometry and Vision Sciences, Cardiff University, Cardiff CF244LU, UK
    Br J Ophthalmol 93:1676-9. 2009
    ..The absence of these interactions would result in a diffuse pattern RGC loss...
  15. ncbi The s-cone PHNR and pattern ERG in primary open angle glaucoma
    N Drasdo
    Department of Optometry and Vision Sciences, Cardiff University, Redwood Building, King Edward VII Avenue, PO Box 905, Cardiff CF10 3YJ, Wales, United Kingdom
    Invest Ophthalmol Vis Sci 42:1266-72. 2001
    ....
  16. ncbi The pattern electroretinogram (PERG) with contralateral corneal reference
    Y H Aldebasi
    Department of Optometry and Vision Sciences, Cardiff University, P.O. Box 905, King Edward VII Avenue, Cardiff, Wales CF10 3YJ, UK
    Ophthalmic Physiol Opt 21:243-6. 2001
    ..001). Because the CCR signal is larger, new normative ranges must be established to avoid false negative results...
  17. ncbi Comparison of laser interferometry and ultrasound A-scan in the measurement of axial length
    R Goyal
    Department of Ophthalmology, University Hospital of Wales, Heath Park, Cardiff CF4 4XW, Wales, UK
    Acta Ophthalmol Scand 81:331-5. 2003
    ..Laser interferometry provides more reproducible results that should improve the accuracy of measurements of axial length in the clinical setting...
  18. ncbi Mouse models of dominant optic atrophy: what do they tell us about the pathophysiology of visual loss?
    P A Williams
    School of Optometry and Vision Sciences, Cardiff University, Cardiff CF24 4LU, United Kingdom
    Vision Res 51:229-34. 2011
    ..Here we summarise the current state of knowledge of the mechanisms of disease based on data from these models of Opa1 DOA...
  19. ncbi The Humphrey optical coherence tomography scanner: quantitative analysis and reproducibility study of the normal human retinal nerve fibre layer
    A L Jones
    Retinal Imaging Laboratory, Department of Optometry and Vision Sciences, Cardiff University, Cardiff CF10 3YJ, UK
    Br J Ophthalmol 85:673-7. 2001
    ..Further refinement of this technology is required to improve the accuracy with which the OCT measures retinal nerve fibre layer thickness...
  20. ncbi Glaucoma: squaring the psychophysics and neurobiology
    E A Ansari
    Department of Ophthalmology, University Hospital of Wales, Cardiff, UK
    Br J Ophthalmol 86:823-6. 2002
    ..These exciting new findings may help us develop psychophysical tests to monitor early retinal ganglion cell damage, possibly before neurons are committed to the process of cell death...
  21. ncbi Psychophysical characterisation of early functional loss in glaucoma and ocular hypertension
    E A Ansari
    Department of Ophthalmology, University of Wales College of Medicine, Cardiff, UK
    Br J Ophthalmol 86:1131-5. 2002
    ..These findings are not consistent with the hypothesis that the magnocellular pathway is selectively damaged in early glaucoma...
  22. ncbi Orbital cellulitis caused by Fusobacterium necrophorum
    J A Escardo
    Cardiff Eye Unit, University Hospital of Wales, Cardiff, Wales CF14 4XW, UK
    Am J Ophthalmol 131:280-1. 2001
    ..We are unaware of previous reports of this condition caused by the same anaerobic, gram-negative, nonsporeforming bacterium and could find no reference to it in a computer search using MEDLINE...
  23. ncbi Measurement of intraocular pressure (IOP) in chickens using a rebound tonometer: quantitative evaluation of variance due to position inaccuracies
    A Prashar
    School of Optometry and Vision Sciences, Cardiff University, Cardiff, Wales, UK
    Exp Eye Res 85:563-71. 2007
    ..However, our preliminary findings highlight several obstacles to mapping such QTL using the chicken advanced intercross line evaluated here...
  24. ncbi Ocular complications of neurological therapy
    S Hadjikoutis
    Department of Neurology, University Hospital of Wales, Cardiff, UK
    Eur J Neurol 12:499-507. 2005
    ..Neurologists must be aware of potential ocular toxicity of these drugs, and appropriately monitor for potential adverse events...
  25. ncbi Pseudophakic cystoid macular oedema: 30 months after latanoprost challenge
    N Dhingra
    Eye 21:269-71. 2007
  26. ncbi Electron and proton transfer in the arginine-54-methionine mutant of cytochrome c oxidase from Paracoccus denitrificans
    A Jasaitis
    Helsinki Bioenergetics Group, Department of Medical Chemistry, Institute of Biomedical Sciences and Biocentrum Helsinki, University of Helsinki, Finland
    Biochemistry 40:5269-74. 2001
    ..From this we conclude that the completely (4e(-)) reduced enzyme is fully capable of proton translocation...
  27. ncbi Histological measurement of retinal nerve fibre layer thickness
    S Frenkel
    Department of Ophthalmology, Hebrew University-Hadassah Medical Center, Jerusalem, Israel
    Eye 19:491-8. 2005
    ..Further studies may help better characterize the RNFL thickness in health and disease and to facilitate the correlation with clinical methods for nerve fibre layer assessment...