Christelle Monville

Summary

Affiliation: Cardiff University
Country: UK

Publications

  1. pmc Astroglial expression of the P-glycoprotein is controlled by intracellular CNTF
    Christelle Monville
    INSERM U421 IM3, Creteil, France
    BMC Cell Biol 3:20. 2002
  2. ncbi Validation of the l-dopa-induced dyskinesia in the 6-OHDA model and evaluation of the effects of selective dopamine receptor agonists and antagonists
    Christelle Monville
    Cardiff University, School of Biosciences, Museum Avenue, Cardiff CF10 3US, UK
    Brain Res Bull 68:16-23. 2005
  3. ncbi Comparison of incremental and accelerating protocols of the rotarod test for the assessment of motor deficits in the 6-OHDA model
    Christelle Monville
    Cardiff University, Cardiff CF10 3US, UK
    J Neurosci Methods 158:219-23. 2006
  4. ncbi The Corridor Task: a simple test of lateralised response selection sensitive to unilateral dopamine deafferentation and graft-derived dopamine replacement in the striatum
    Eilis Dowd
    Brain Repair Group, School of Biosciences, Cardiff University, Cardiff, CF10 3US Wales, UK
    Brain Res Bull 68:24-30. 2005
  5. ncbi Lentivector-mediated delivery of GDNF protects complex motor functions relevant to human Parkinsonism in a rat lesion model
    Eilis Dowd
    Brain Repair Group, School of Biosciences, Cardiff University, Wales, UK
    Eur J Neurosci 22:2587-95. 2005
  6. ncbi HSV vector-delivery of GDNF in a rat model of PD: partial efficacy obscured by vector toxicity
    Christelle Monville
    School of Biosciences, Cardiff University, Museum Avenue, Cardiff CF10 3US, Wales, UK
    Brain Res 1024:1-15. 2004
  7. ncbi Gene therapy in Parkinson's disease: dream or reality?
    Christelle Monville
    Neuroreport 13:743. 2002
  8. ncbi Corticostriatopallidal neuroprotection by adenovirus-mediated ciliary neurotrophic factor gene transfer in a rat model of progressive striatal degeneration
    Vincent Mittoux
    Unité de Recherche Associée 2210, Commissariat a l Energie Atomique, Centre National de la Recherche Scientifique, Service Hospitalier Frederic Joliot, 91401 Orsay Cedex, France
    J Neurosci 22:4478-86. 2002

Collaborators

Detail Information

Publications8

  1. pmc Astroglial expression of the P-glycoprotein is controlled by intracellular CNTF
    Christelle Monville
    INSERM U421 IM3, Creteil, France
    BMC Cell Biol 3:20. 2002
    ..In a search for factors involved in this modulation, P-gp overexpression was studied in long-term in vitro astroglial cultures...
  2. ncbi Validation of the l-dopa-induced dyskinesia in the 6-OHDA model and evaluation of the effects of selective dopamine receptor agonists and antagonists
    Christelle Monville
    Cardiff University, School of Biosciences, Museum Avenue, Cardiff CF10 3US, UK
    Brain Res Bull 68:16-23. 2005
    ..g. using grafts while blocking the unwanted adverse effects of the drugs...
  3. ncbi Comparison of incremental and accelerating protocols of the rotarod test for the assessment of motor deficits in the 6-OHDA model
    Christelle Monville
    Cardiff University, Cardiff CF10 3US, UK
    J Neurosci Methods 158:219-23. 2006
    ..We report that whereas the incremental protocol is more sensitive to detect the presence of a lesion, the accelerating protocol provides a more discriminative test to correlate motor deficits against lesion size...
  4. ncbi The Corridor Task: a simple test of lateralised response selection sensitive to unilateral dopamine deafferentation and graft-derived dopamine replacement in the striatum
    Eilis Dowd
    Brain Repair Group, School of Biosciences, Cardiff University, Cardiff, CF10 3US Wales, UK
    Brain Res Bull 68:24-30. 2005
    ..We conclude that the Corridor Task is a sensitive test of lateralised sensorimotor response selection, and is suitable for assessing deficits and recovery associated with lesions and grafts within the nigrostriatal system...
  5. ncbi Lentivector-mediated delivery of GDNF protects complex motor functions relevant to human Parkinsonism in a rat lesion model
    Eilis Dowd
    Brain Repair Group, School of Biosciences, Cardiff University, Wales, UK
    Eur J Neurosci 22:2587-95. 2005
    ..This study confirms that GDNF can protect against 6-OHDA-induced impairments in complex as well as simple behaviours, and reinforces the use of EIAV-based vectors for the treatment of PD...
  6. ncbi HSV vector-delivery of GDNF in a rat model of PD: partial efficacy obscured by vector toxicity
    Christelle Monville
    School of Biosciences, Cardiff University, Museum Avenue, Cardiff CF10 3US, Wales, UK
    Brain Res 1024:1-15. 2004
    ..This was found to be due to the way the vector was purified. The issue of toxicity, which might account for the variable functional effects, needs resolving prior to therapeutic application of these vectors...
  7. ncbi Gene therapy in Parkinson's disease: dream or reality?
    Christelle Monville
    Neuroreport 13:743. 2002
  8. ncbi Corticostriatopallidal neuroprotection by adenovirus-mediated ciliary neurotrophic factor gene transfer in a rat model of progressive striatal degeneration
    Vincent Mittoux
    Unité de Recherche Associée 2210, Commissariat a l Energie Atomique, Centre National de la Recherche Scientifique, Service Hospitalier Frederic Joliot, 91401 Orsay Cedex, France
    J Neurosci 22:4478-86. 2002
    ..Overall, adenovirus-mediated CNTF gene transfer appears to be a potentially useful delivery system for widespread, long-term circuit neuroprotection in HD patients...