K I Mills

Summary

Affiliation: Cardiff University
Country: UK

Publications

  1. ncbi request reprint Inhibition of mitochondrial function in HL60 cells is associated with an increased apoptosis and expression of CD14
    K I Mills
    Department of Haematology, University of Wales College of Medicine, Cardiff, Heath Park, United Kingdom
    Biochem Biophys Res Commun 263:294-300. 1999
  2. ncbi request reprint Identification of a retinoic acid responsive aldoketoreductase expressed in HL60 leukaemic cells
    K I Mills
    Department of Haematology, University of Wales College of Medicine, Cardiff, UK
    FEBS Lett 440:158-62. 1998
  3. ncbi request reprint An in vivo and in vitro comparison of the effects of b2-a2 and b3-a2 p210BCR-ABL splice variants on murine 32D cells
    B A Guinn
    Department of Haematology, University of Wales College of Medicine, Cardiff, United Kingdom
    Leuk Lymphoma 37:393-404. 2000
  4. ncbi request reprint Unravelling an HLA-DR association in childhood acute lymphoblastic leukemia
    M T Dorak
    Department of Haematology, University of Wales College of Medicine, Cardiff, Wales, UK
    Blood 94:694-700. 1999
  5. ncbi request reprint Abnormalities of adherent layers grown from bone marrow of patients with myelodysplasia
    G B Tennant
    Department of Haematology, University of Wales College of Medicine, Cardiff, UK
    Br J Haematol 111:853-62. 2000
  6. ncbi request reprint Differential display as an approach to study differentiation and differentiation therapy in AML
    K I Mills
    Department of Haematology, University of Wales College of Medicine, Cardiff, Wales, UK
    Hematol Oncol 18:129-140. 2000
  7. ncbi request reprint Increasing methylation of the calcitonin gene during disease progression in sequential samples from CML patients
    K I Mills
    Department of Haematology, University of Wales College of Medicine, Cardiff, U K
    Leuk Res 20:771-5. 1996
  8. ncbi request reprint Transcriptional dysregulation mediated by RUNX1-RUNX1T1 in normal human progenitor cells and in acute myeloid leukaemia
    A Tonks
    Department of Haematology, School of Medicine, Cardiff University, Cardiff, UK
    Leukemia 21:2495-505. 2007
  9. ncbi request reprint Increased heterozygosity for MHC class II lineages in newborn males
    M T Dorak
    Department of Haematology, University of Wales College of Medicine, Cardiff CF14 4XN, UK
    Genes Immun 3:263-9. 2002
  10. ncbi request reprint Elevated Bcr-Abl expression levels are sufficient for a haematopoietic cell line to acquire a drug-resistant phenotype
    K Keeshan
    Department of Biochemistry, University College Cork, Ireland
    Leukemia 15:1823-33. 2001

Detail Information

Publications11

  1. ncbi request reprint Inhibition of mitochondrial function in HL60 cells is associated with an increased apoptosis and expression of CD14
    K I Mills
    Department of Haematology, University of Wales College of Medicine, Cardiff, Heath Park, United Kingdom
    Biochem Biophys Res Commun 263:294-300. 1999
    ..These results suggest that inhibition of the components of the mitochondrial pathways may lead to the marking of some cells, via CD14, for cell death, whilst allowing commitment to differentiation to occur in the surviving population...
  2. ncbi request reprint Identification of a retinoic acid responsive aldoketoreductase expressed in HL60 leukaemic cells
    K I Mills
    Department of Haematology, University of Wales College of Medicine, Cardiff, UK
    FEBS Lett 440:158-62. 1998
    ....
  3. ncbi request reprint An in vivo and in vitro comparison of the effects of b2-a2 and b3-a2 p210BCR-ABL splice variants on murine 32D cells
    B A Guinn
    Department of Haematology, University of Wales College of Medicine, Cardiff, United Kingdom
    Leuk Lymphoma 37:393-404. 2000
    ..This panel of BCR-ABL expressing 32D cells provides a useful model for CML disease progression studies...
  4. ncbi request reprint Unravelling an HLA-DR association in childhood acute lymphoblastic leukemia
    M T Dorak
    Department of Haematology, University of Wales College of Medicine, Cardiff, Wales, UK
    Blood 94:694-700. 1999
    ....
  5. ncbi request reprint Abnormalities of adherent layers grown from bone marrow of patients with myelodysplasia
    G B Tennant
    Department of Haematology, University of Wales College of Medicine, Cardiff, UK
    Br J Haematol 111:853-62. 2000
    ..Thus, the adherent layers in cultures grown from MDS patients were haemopoietically defective and showed abnormal IL-1 beta expression...
  6. ncbi request reprint Differential display as an approach to study differentiation and differentiation therapy in AML
    K I Mills
    Department of Haematology, University of Wales College of Medicine, Cardiff, Wales, UK
    Hematol Oncol 18:129-140. 2000
    ..This article describes how the technique of differential display, as one of several possible methods of molecular screening, may allow the identification of genes which can be targeted to induce differentiation...
  7. ncbi request reprint Increasing methylation of the calcitonin gene during disease progression in sequential samples from CML patients
    K I Mills
    Department of Haematology, University of Wales College of Medicine, Cardiff, U K
    Leuk Res 20:771-5. 1996
    ....
  8. ncbi request reprint Transcriptional dysregulation mediated by RUNX1-RUNX1T1 in normal human progenitor cells and in acute myeloid leukaemia
    A Tonks
    Department of Haematology, School of Medicine, Cardiff University, Cardiff, UK
    Leukemia 21:2495-505. 2007
    ..These data provide the most comprehensive and pertinent assessment of the effect of RUNX1-RUNX1T1 on gene expression and demonstrate the highly context-dependent effects of this fusion gene...
  9. ncbi request reprint Increased heterozygosity for MHC class II lineages in newborn males
    M T Dorak
    Department of Haematology, University of Wales College of Medicine, Cardiff CF14 4XN, UK
    Genes Immun 3:263-9. 2002
    ..These results provide an appealing working hypothesis for further studies in humans and other vertebrates...
  10. ncbi request reprint Elevated Bcr-Abl expression levels are sufficient for a haematopoietic cell line to acquire a drug-resistant phenotype
    K Keeshan
    Department of Biochemistry, University College Cork, Ireland
    Leukemia 15:1823-33. 2001
    ..Our study indicates that drug resistance can be primarily attained by increased Bcr-Abl expression, and highlights the potential of therapy which combines STI571 with conventional cytotoxic drugs...
  11. ncbi request reprint CD200 as a prognostic factor in acute myeloid leukaemia
    A Tonks
    Leukemia 21:566-8. 2007