Daryn R Michael

Summary

Affiliation: Cardiff University
Country: UK

Publications

  1. doi request reprint Liver X receptors, atherosclerosis and inflammation
    Daryn R Michael
    Cardiff School of Biosciences, Cardiff University, UK
    Curr Atheroscler Rep 14:284-93. 2012
  2. pmc TGF-β inhibits the uptake of modified low density lipoprotein by human macrophages through a Smad-dependent pathway: a dominant role for Smad-2
    Daryn R Michael
    Cardiff School of Biosciences, Cardiff University, Cardiff, UK
    Biochim Biophys Acta 1822:1608-16. 2012
  3. doi request reprint Cytokines, macrophage lipid metabolism and foam cells: implications for cardiovascular disease therapy
    James E McLaren
    Cardiff School of Biosciences, Cardiff University, Museum Avenue, Cardiff CF10 3AX, UK
    Prog Lipid Res 50:331-47. 2011
  4. pmc The expression of a disintegrin and metalloproteinase with thrombospondin motifs 4 in human macrophages is inhibited by the anti-atherogenic cytokine transforming growth factor-β and requires Smads, p38 mitogen-activated protein kinase and c-Jun
    Rebecca C Salter
    Cardiff School of Biosciences, Cardiff University, Museum Avenue, Cardiff CF10 3AX, United Kingdom
    Int J Biochem Cell Biol 43:805-11. 2011
  5. doi request reprint Eicosapentaenoic acid and docosahexaenoic acid regulate modified LDL uptake and macropinocytosis in human macrophages
    James E McLaren
    Cardiff School of Biosciences, Cardiff University, Museum Avenue, Cardiff, CF10 3AX, UK
    Lipids 46:1053-61. 2011
  6. pmc Differential regulation of macropinocytosis in macrophages by cytokines: Implications for foam cell formation and atherosclerosis
    Daryn R Michael
    Cardiff School of Biosciences, Cardiff University, Museum Avenue, Cardiff CF10 3AX, United Kingdom Electronic address
    Cytokine 64:357-61. 2013
  7. doi request reprint IL-33 reduces macrophage foam cell formation
    James E McLaren
    Cardiff School of Biosciences, Cardiff University, Cardiff, United Kingdom
    J Immunol 185:1222-9. 2010

Detail Information

Publications7

  1. doi request reprint Liver X receptors, atherosclerosis and inflammation
    Daryn R Michael
    Cardiff School of Biosciences, Cardiff University, UK
    Curr Atheroscler Rep 14:284-93. 2012
    ..In addition, we discuss the major limitations of LXRs as therapeutic targets for the treatment of atherosclerosis and how these are being addressed...
  2. pmc TGF-β inhibits the uptake of modified low density lipoprotein by human macrophages through a Smad-dependent pathway: a dominant role for Smad-2
    Daryn R Michael
    Cardiff School of Biosciences, Cardiff University, Cardiff, UK
    Biochim Biophys Acta 1822:1608-16. 2012
    ....
  3. doi request reprint Cytokines, macrophage lipid metabolism and foam cells: implications for cardiovascular disease therapy
    James E McLaren
    Cardiff School of Biosciences, Cardiff University, Museum Avenue, Cardiff CF10 3AX, UK
    Prog Lipid Res 50:331-47. 2011
    ..A clear understanding of macrophage foam cell biology will hopefully enable novel foam cell targeting therapies to be developed for use in the clinical intervention of atherosclerosis...
  4. pmc The expression of a disintegrin and metalloproteinase with thrombospondin motifs 4 in human macrophages is inhibited by the anti-atherogenic cytokine transforming growth factor-β and requires Smads, p38 mitogen-activated protein kinase and c-Jun
    Rebecca C Salter
    Cardiff School of Biosciences, Cardiff University, Museum Avenue, Cardiff CF10 3AX, United Kingdom
    Int J Biochem Cell Biol 43:805-11. 2011
    ..The inhibition of macrophage ADAMTS-4 expression is likely to contribute to the anti-atherogenic, plaque stabilisation action of TGF-β...
  5. doi request reprint Eicosapentaenoic acid and docosahexaenoic acid regulate modified LDL uptake and macropinocytosis in human macrophages
    James E McLaren
    Cardiff School of Biosciences, Cardiff University, Museum Avenue, Cardiff, CF10 3AX, UK
    Lipids 46:1053-61. 2011
    ....
  6. pmc Differential regulation of macropinocytosis in macrophages by cytokines: Implications for foam cell formation and atherosclerosis
    Daryn R Michael
    Cardiff School of Biosciences, Cardiff University, Museum Avenue, Cardiff CF10 3AX, United Kingdom Electronic address
    Cytokine 64:357-61. 2013
    ..Furthermore we show that the TGF-β-mediated inhibition of macropinocytosis is a Smad-2/-3-independent process. ..
  7. doi request reprint IL-33 reduces macrophage foam cell formation
    James E McLaren
    Cardiff School of Biosciences, Cardiff University, Cardiff, United Kingdom
    J Immunol 185:1222-9. 2010
    ..In conclusion, IL-33 has a protective role in atherosclerosis by reducing macrophage foam cell formation suggesting that IL-33 maybe a potential therapeutic agent against atherosclerosis...