Tracey Amanda Martin

Summary

Affiliation: Cardiff University
Country: UK

Publications

  1. pmc The Expression of the Nectin Complex in Human Breast Cancer and the Role of Nectin-3 in the Control of Tight Junctions during Metastasis
    Tracey A Martin
    Cardiff University Peking University Cancer Research Institute, Cardiff School of Medicine, Cardiff University, Heath Park, Cardiff, United Kingdom
    PLoS ONE 8:e82696. 2013
  2. pmc Real time PCR analyses of expression of E-cadherin, alpha-, beta- and gamma-catenin in human breast cancer for predicting clinical outcome
    Amit Goyal
    Department of Surgery, School of Medicine, Cardiff University, Cardiff, UK
    World J Surg Oncol 6:56. 2008
  3. pmc Eplin-alpha expression in human breast cancer, the impact on cellular migration and clinical outcome
    Wen G Jiang
    Metastasis and Angiogenesis Research Group, Cardiff University School of Medicine, Heath Park, Cardiff CF14 4XN, UK
    Mol Cancer 7:71. 2008
  4. pmc The expression and prognostic value of the guanine nucleotide exchange factors (GEFs) Trio, Vav1 and TIAM-1 in human breast cancer
    Jane Lane
    Metastasis Research Group, University Department of Surgery, Cardiff University School of Medicine, Heath Park, Cardiff, CF4 4XN, UK
    Int Semin Surg Oncol 5:23. 2008
  5. ncbi request reprint Assessing microvessels and angiogenesis in human breast cancer, using VE-cadherin
    T A Martin
    Metastasis Research Group, University Department of Surgery, University of Wales College of Medicine, Cardiff, UK
    Histopathology 46:422-30. 2005
  6. ncbi request reprint Expression of the transcription factors snail, slug, and twist and their clinical significance in human breast cancer
    Tracey A Martin
    Metastasis and Angiogenesis Research Group, University Department of Surgery, Wales College of Medicine, Cardiff University, Cardiff CF14 4XN, UK
    Ann Surg Oncol 12:488-96. 2005
  7. ncbi request reprint N-WASP is a putative tumour suppressor in breast cancer cells, in vitro and in vivo, and is associated with clinical outcome in patients with breast cancer
    Tracey A Martin
    Metastasis and Angiogenesis Research Group, Department of Surgery, Wales College of Medicine, Cardiff University, Cardiff CF14 4XN, UK
    Clin Exp Metastasis 25:97-108. 2008
  8. ncbi request reprint Hepatocyte growth factor modulates vascular endothelial-cadherin expression in human endothelial cells
    T A Martin
    University Department of Surgery, University of Wales College of Medicine, Cardiff, United Kingdom
    Clin Cancer Res 7:734-7. 2001
  9. ncbi request reprint The Coxsackie-adenovirus receptor has elevated expression in human breast cancer
    T A Martin
    Metastasis and Angiogenesis Research Group, University Department of Surgery, Wales College of Medicine, Cardiff University, Heath Park, Cardiff CF14 4XN, UK
    Clin Exp Med 5:122-8. 2005
  10. ncbi request reprint KiSS-1 expression in human breast cancer
    Tracey A Martin
    Metastasis and Angiogenesis Research Group, University Department of Surgery, Wales College of Medicine, Cardiff University, Cardiff, UK
    Clin Exp Metastasis 22:503-11. 2005

Detail Information

Publications48

  1. pmc The Expression of the Nectin Complex in Human Breast Cancer and the Role of Nectin-3 in the Control of Tight Junctions during Metastasis
    Tracey A Martin
    Cardiff University Peking University Cancer Research Institute, Cardiff School of Medicine, Cardiff University, Heath Park, Cardiff, United Kingdom
    PLoS ONE 8:e82696. 2013
    ..This study aimed to ascertain the distribution of Nectins-1 to -4 in human breast cancer and the effect on junctional integrity of Nectin-3 modulation in human endothelial and breast cancer cells...
  2. pmc Real time PCR analyses of expression of E-cadherin, alpha-, beta- and gamma-catenin in human breast cancer for predicting clinical outcome
    Amit Goyal
    Department of Surgery, School of Medicine, Cardiff University, Cardiff, UK
    World J Surg Oncol 6:56. 2008
    ..The E-cadherin catenin system acts as an invasion suppressor of epithelial malignancies. However, it is debatable whether expression of E-cadherin or catenins is a useful prognostic marker in invasive breast cancer...
  3. pmc Eplin-alpha expression in human breast cancer, the impact on cellular migration and clinical outcome
    Wen G Jiang
    Metastasis and Angiogenesis Research Group, Cardiff University School of Medicine, Heath Park, Cardiff CF14 4XN, UK
    Mol Cancer 7:71. 2008
    ..To investigate the expression of EPLIN-alpha, epithelial protein lost in neoplasm, in human breast cancer tissues/cells and investigate the cellular impact of EPLIN-alpha on breast cancer cells...
  4. pmc The expression and prognostic value of the guanine nucleotide exchange factors (GEFs) Trio, Vav1 and TIAM-1 in human breast cancer
    Jane Lane
    Metastasis Research Group, University Department of Surgery, Cardiff University School of Medicine, Heath Park, Cardiff, CF4 4XN, UK
    Int Semin Surg Oncol 5:23. 2008
    ..The purpose of this study was to investigate the expression of these GEFs, in human breast cancer and assess the affect on clinical outcome...
  5. ncbi request reprint Assessing microvessels and angiogenesis in human breast cancer, using VE-cadherin
    T A Martin
    Metastasis Research Group, University Department of Surgery, University of Wales College of Medicine, Cardiff, UK
    Histopathology 46:422-30. 2005
    ....
  6. ncbi request reprint Expression of the transcription factors snail, slug, and twist and their clinical significance in human breast cancer
    Tracey A Martin
    Metastasis and Angiogenesis Research Group, University Department of Surgery, Wales College of Medicine, Cardiff University, Cardiff CF14 4XN, UK
    Ann Surg Oncol 12:488-96. 2005
    ..We examined the distribution and expression of these three molecules together with the methylation of the Twist gene promoter in human breast cancer to elucidate their clinical significance...
  7. ncbi request reprint N-WASP is a putative tumour suppressor in breast cancer cells, in vitro and in vivo, and is associated with clinical outcome in patients with breast cancer
    Tracey A Martin
    Metastasis and Angiogenesis Research Group, Department of Surgery, Wales College of Medicine, Cardiff University, Cardiff CF14 4XN, UK
    Clin Exp Metastasis 25:97-108. 2008
    ..It is concluded that N-WASP, a member of the N-WASP family may act as a tumour progression suppressor in human breast cancer and may therefore have significant clinical value in this condition...
  8. ncbi request reprint Hepatocyte growth factor modulates vascular endothelial-cadherin expression in human endothelial cells
    T A Martin
    University Department of Surgery, University of Wales College of Medicine, Cardiff, United Kingdom
    Clin Cancer Res 7:734-7. 2001
    ..These results show, for the first time, that HGF/SF targets the endothelial cell-specific adhesion molecule VE-cadherin...
  9. ncbi request reprint The Coxsackie-adenovirus receptor has elevated expression in human breast cancer
    T A Martin
    Metastasis and Angiogenesis Research Group, University Department of Surgery, Wales College of Medicine, Cardiff University, Heath Park, Cardiff CF14 4XN, UK
    Clin Exp Med 5:122-8. 2005
    ..We conclude that CAR expression is elevated in primary breast cancers. This may have a bearing on its use as means of delivery for gene therapy and suggests that further work is necessary to understand this complex molecule...
  10. ncbi request reprint KiSS-1 expression in human breast cancer
    Tracey A Martin
    Metastasis and Angiogenesis Research Group, University Department of Surgery, Wales College of Medicine, Cardiff University, Cardiff, UK
    Clin Exp Metastasis 22:503-11. 2005
    ..Over-expression of KiSS-1 in breast cancer cells result in more aggressive phenotype. Together, it suggests that KiSS-1 plays a role beyond the initial metastasis repressor in this cancer type...
  11. ncbi request reprint Synergistic regulation of endothelial tight junctions by antioxidant (Se) and polyunsaturated lipid (GLA) via Claudin-5 modulation
    Tracey A Martin
    Department of Surgery, Metastasis and Angiogenesis Research Group, Wales College of Medicine, Cardiff University, Heath Park, Cardiff, UK
    J Cell Biochem 98:1308-19. 2006
    ..Interestingly, this combination was also able to completely reverse the effect of 17beta-estradiol in these cells...
  12. ncbi request reprint Expression of breast cancer specific gene-1 (BCSG-1/gamma-synuclein) is associated with tumour grade but not with clinical outcome of patients with breast cancer
    Tracey A Martin
    Metastasis and Angiogenesis Research Group, Wales College of Medicine, Cardiff University, Heath Park, Cardiff, CF4 4XN, UK
    Oncol Rep 16:207-12. 2006
    ..307, P < 0.05), and weakly with transglutaminase-7 (r = 0.183). BCSG-1 is increased in breast tumour cells, is negatively associated with tumour grade and significantly correlates with levels of transglutaminase-3...
  13. doi request reprint Loss of tight junction barrier function and its role in cancer metastasis
    Tracey A Martin
    Department of Surgery, School of Medicine, Cardiff University, Heath Park, Cardiff, CF14 4XN, UK
    Biochim Biophys Acta 1788:872-91. 2009
    ..This article will present data showing how modulation of expression of TJ molecules results in key changes in TJ barrier function leading to the successful metastasis of a number of different cancer types...
  14. ncbi request reprint Hepatocyte growth factor and its receptor signalling complex as targets in cancer therapy
    Tracey A Martin
    Department of Surgery, Cardiff University, Heath Park, UK
    Anticancer Agents Med Chem 10:2-6. 2010
    ..This issue will focus on recent work that shows strong indications for the value of HGF and cMET in clinical settings...
  15. ncbi request reprint Tight junctions and their role in cancer metastasis
    T A Martin
    Metastasis Research Group, University Department of Surgery, University of Wales College of Medicine, Cardiff, UK
    Histol Histopathol 16:1183-95. 2001
    ..Further work is required to fully realise the potential that this structure has in cancer invasion and metastasis in order to develop new and novel therapies in the prevention of tumour metastasis...
  16. ncbi request reprint Matrix-bound fibroblasts regulate angiogenesis by modulation of VE-cadherin
    T A Martin
    Department of Surgery, University of Wales College of Medicine, Heath Park, Cardiff, CF14 4XN, Wales, UK
    Eur J Clin Invest 31:931-8. 2001
    ..Matrix-bound fibroblasts have been show to produce a number of factors that are important in inducing angiogenesis and to promote tubule-formation by human endothelial cells, an indicator of angiogenic potential...
  17. doi request reprint Claudin-16/paracellin-1, cloning, expression, and its role in tight junction functions in cancer and endothelial cells
    Tracey A Martin
    Metastasis and Angiogenesis Research Group, University Department of Surgery, Cardiff School of Medicine, Cardiff University, Cardiff, UK
    Methods Mol Biol 762:383-407. 2011
    ..J Cell Biochem 105:41-52,2008). This suggests that claudin-16 plays a role beyond that of an initial metastasis repressor in this cancer type...
  18. ncbi request reprint Antagonistic effect of NK4 on HGF/SF induced changes in the transendothelial resistance (TER) and paracellular permeability of human vascular endothelial cells
    Tracey A Martin
    Metastasis Research Group, University Department of Surgery, University of Wales College of Medicine, Heath Park, Cardiff, United Kingdom
    J Cell Physiol 192:268-75. 2002
    ..NK4 was able to prevent the decrease in levels of ZO-1 protein by HGF/SF...
  19. ncbi request reprint The role of the CD44/ezrin complex in cancer metastasis
    Tracey A Martin
    Metastasis Research Group, University Department of Surgery, University of Wales College of Medicine, Heath Park, Cardiff, S Wales CF14 4XN, UK
    Crit Rev Oncol Hematol 46:165-86. 2003
    ..This article reviews the role of CD44, ezrin family and the CD44/ezrin complex in cancer cells and their clinical impact in patients with cancer...
  20. ncbi request reprint HAVcR-1 reduces the integrity of human endothelial tight junctions
    Tracey A Martin
    Metastasis and Angiogenesis Research Group, Department of Surgery, Cardiff School of Medicine, Cardiff University, Heath Park, Cardiff CF14 4XN, UK
    Anticancer Res 31:467-73. 2011
    ..Although HAVcR-1 is expressed in every human organ, its natural function remains unknown. This study investigated the location, association and functionality of HAVcR-1 in human endothelial cells...
  21. ncbi request reprint Tight junctions in cancer metastasis
    Tracey A Martin
    Metastasis and Angiogenesis Research Group, School of Medicine, Cardiff University, Heath Park, Cardiff CF14 4XN, UK
    Front Biosci (Landmark Ed) 16:898-936. 2011
    ..This review will discuss how modulation of expression of TJ molecules results in key changes in TJ barrier function leading to the progression of cancer and progression of metastasis...
  22. ncbi request reprint Hepatocyte growth factor disrupts tight junctions in human breast cancer cells
    Tracey A Martin
    Metastasis Research Group, University Department of Surgery, University of Wales College of Medicine, Heath Park, Cardiff CF14 4XN, UK
    Cell Biol Int 28:361-71. 2004
    ..We conclude that regulation of tight junctions could be of fundamental importance in the prevention of metastasis of breast cancer cells...
  23. ncbi request reprint Enhanced tight junction function in human breast cancer cells by antioxidant, selenium and polyunsaturated lipid
    Tracey A Martin
    Metastasis and Angiogenesis Research Group, Department of Surgery, Wales College of Medicine, Cardiff University, Cardiff, United Kingdom
    J Cell Biochem 101:155-66. 2007
    ..This combination also completely reversed the effect of 17-beta-estradiol in these cells...
  24. ncbi request reprint Effect of human fibroblast-derived dermis on expansion of tissue from venous leg ulcers
    Tracey Amanda Martin
    Metastasis Research Group, University Department of Surgery, University of Wales College of Medicine, Cardiff, Wales, United Kingdom
    Wound Repair Regen 11:292-6. 2003
    ..These experimental findings may explain the enhanced healing seen with clinical applications of human fibroblast-derived dermis on chronic wounds...
  25. ncbi request reprint Loss of occludin leads to the progression of human breast cancer
    Tracey A Martin
    Metastasis and Angiogenesis Research Group, Department of Surgery, School of Medicine, Cardiff University, Heath Park, Cardiff, CF14 4XN, UK
    Int J Mol Med 26:723-34. 2010
    ..This loss of or aberrant expression has clear repercussions as to the importance of occludin in maintaining TJ integrity in breast tissues. Such inappropriate expression could play a part in breast cancer development...
  26. doi request reprint Phospholipase-C gamma-1 (PLCgamma-1) is critical in hepatocyte growth factor induced in vitro invasion and migration without affecting the growth of prostate cancer cells
    Gaynor Davies
    Metastasis and Angiogenesis Research Group, Department of Surgery, School of Medicine, Cardiff University, Cardiff, United Kingdom
    Urol Oncol 26:386-91. 2008
    ..This study sought to determine the effect of HGF on the invasive and migratory potential of prostate cancer cells targeted by a ribozyme transgene to PLCgamma-1...
  27. ncbi request reprint Genetic reduction of matriptase-1 expression is associated with a reduction in the aggressive phenotype of prostate cancer cells in vitro and in vivo
    Andrew J Sanders
    Metastasis and Angiogenesis Research Group, Department of Surgery, Wales College of Medicine, Cardiff University, Heath Park, Cardiff CF14 4XN, United Kingdom
    J Exp Ther Oncol 6:39-48. 2006
    ..In the current study we assessed the efficacy of targeting matriptase-1 using ribozyme technology in vitro and in vivo...
  28. doi request reprint Claudin-16 reduces the aggressive behavior of human breast cancer cells
    Tracey A Martin
    Metastasis and Angiogenesis Research Group, School of Medicine, Cardiff University, Heath Park, Cardiff CF14 4XN, UK
    J Cell Biochem 105:41-52. 2008
    ..Claudin-16 expression was reduced in human breast cancer, particularly in patients with aggressive tumors and high mortality. This suggests that Claudin-16 plays a role beyond that of an initial metastasis repressor in this cancer type...
  29. ncbi request reprint Genetic upregulation of matriptase-2 reduces the aggressiveness of prostate cancer cells in vitro and in vivo and affects FAK and paxillin localisation
    Andrew J Sanders
    Metastasis and Angiogenesis Research Group, Cardiff University School of Medicine, Cardiff, UK
    J Cell Physiol 216:780-9. 2008
    ..Furthermore, the data presented implies a possible connection between matriptase-2 and the paxillin and FAK adhesion molecules which may ultimately contribute to the reduced migration rates seen in this study...
  30. ncbi request reprint The expression and prognostic value of ROCK I and ROCK II and their role in human breast cancer
    Jane Lane
    Metastasis and Angiogenesis Research Group, University Department of Surgery, Wales College of Medicine, Cardiff University, Heath Park, Cardiff CF14 4XN, UK
    Int J Oncol 33:585-93. 2008
    ..This, together with significant correlation between ROCKI and poor outcome in clinical breast cancer, indicates that it is a potential target in human breast cancer...
  31. ncbi request reprint Tuberin and hamartin are aberrantly expressed and linked to clinical outcome in human breast cancer: the role of promoter methylation of TSC genes
    Wen G Jiang
    Metastasis and Angiogenesis Research Group, University Department of Surgery, Wales College of Medicine, Cardiff University, UK
    Eur J Cancer 41:1628-36. 2005
    ..However, the TSC genes have not been studied in breast cancer. The current study investigated the expression of the TSC gene products and the potential mechanisms of their aberrancy in human breast cancer cells and tissues...
  32. ncbi request reprint Com-1/p8 acts as a putative tumour suppressor in prostate cancer
    Wen G Jiang
    Metastasis and Angiogenesis Research Group, Cardiff University School of Medicine, Cardiff CF14 4XN, UK
    Int J Mol Med 18:981-6. 2006
    ..Com-1/p8 is a potential tumour suppressor in human prostate cancer...
  33. ncbi request reprint Reduction of stromal fibroblast-induced mammary tumor growth, by retroviral ribozyme transgenes to hepatocyte growth factor/scatter factor and its receptor, c-MET
    Wen G Jiang
    Metastasis Research Group, University Department of Surgery, University of Wales College of Medicine, Cardiff CF14 4XN, Wales, UK
    Clin Cancer Res 9:4274-81. 2003
    ..This study examined if inhibition of HGF/SF receptor expression by cancer cells and HGF/SF expression by stromal fibroblasts affects the growth of mammary cancer...
  34. ncbi request reprint Loss of tight junction plaque molecules in breast cancer tissues is associated with a poor prognosis in patients with breast cancer
    Tracey A Martin
    Metastasis and Angiogenesis Research Group, Department of Surgery, University of Wales College of Medicine, Heath Park, Cardiff, Wales CF14 4XN, UK
    Eur J Cancer 40:2717-25. 2004
    ..We conclude that low levels of tight junction plaque molecules, such as ZO-1 and MUPP-1, in breast cancer are associated with poor patients prognosis...
  35. ncbi request reprint Biphasic effects of 17-beta-estradiol on expression of occludin and transendothelial resistance and paracellular permeability in human vascular endothelial cells
    Lin Ye
    Metastasis Research Group, University Department of Surgery, University of Wales College of Medicine, Cardiff, United Kingdom
    J Cell Physiol 196:362-9. 2003
    ....
  36. ncbi request reprint Hepatocyte growth factor, its receptor, and their potential value in cancer therapies
    Wen G Jiang
    Metastasis and Angiogenesis Research Group, University Department of Surgery, Wales College of Medicine, Cardiff University, Heath Park, Cardiff CF14 4XN, UK
    Crit Rev Oncol Hematol 53:35-69. 2005
    ..The current article discusses the potential value of HGF and its receptor as targets in cancer therapies, the current development in anti-HGF research, and the clinical value of HGF in prognosis and treatment...
  37. ncbi request reprint Growth and angiogenesis of human breast cancer in a nude mouse tumour model is reduced by NK4, a HGF/SF antagonist
    Tracey A Martin
    Metastasis Research Group, University Department of Surgery, University of Wales College of Medicine, Heath Park, Cardiff CF14 4XN, UK
    Carcinogenesis 24:1317-23. 2003
    ..This may occur by decreasing angiogenesis. This gives a clear indication of the therapeutic worth of NK4...
  38. ncbi request reprint Molecular detection of micro-metastasis in breast cancer
    Wen G Jiang
    Metastasis Research Group, University Department of Surgery, University of Wales College of Medicine, Heath Park, Cardiff CF14 4XN, UK
    Crit Rev Oncol Hematol 43:13-31. 2002
    ..The current article discusses recent developments, in the detection of micro-metastasis using molecular biology techniques...
  39. ncbi request reprint Targeting matrilysin and its impact on tumor growth in vivo: the potential implications in breast cancer therapy
    Wen G Jiang
    Metastasis and Angiogenesis Research Group, Wales College of Medicine, Cardiff University, Cardiff, United Kingdom
    Clin Cancer Res 11:6012-9. 2005
    ..The current study examined if targeting matrilysin using retroviral ribozyme transgenes may have an impact on breast cancer cells and may have clinical implications...
  40. ncbi request reprint The potential lymphangiogenic effects of hepatocyte growth factor/scatter factor in vitro and in vivo
    Wen G Jiang
    Metastasis and Angiogenesis Research Group, Wales College of Medicine, Cardiff University, Heath Park, Cardiff CF4 4XN, UK
    Int J Mol Med 16:723-8. 2005
    ..Hepatocyte growth factor has potential lymphangiogenic activities, and this may have important implications in the nodal spread of cancer cells...
  41. ncbi request reprint Expression of membrane type-1 matrix metalloproteinase, MT1-MMP in human breast cancer and its impact on invasiveness of breast cancer cells
    Wen G Jiang
    Metastasis and Angiogenesis Research Group, University Department of Surgery, Wales College of Medicine, Cardiff University, Cardiff, CF14 4XN, UK
    Int J Mol Med 17:583-90. 2006
    ..It is highly expressed in aggressive breast tumours and is associated with clinical outcome. The enzyme is a potential therapeutic target in breast cancer...
  42. ncbi request reprint Expression of interleukin 11 and its receptor and their prognostic value in human breast cancer
    Satheesha Hanavadi
    University Department of Surgery, Wales College of Medicine, Cardiff University, Heath Park, Cardiff, CF4 4XN, United Kingdom
    Ann Surg Oncol 13:802-8. 2006
    ..However, there is little clinical information to support this hypothesis. We examined the expression of IL-11 and its receptor in primary breast cancer tissue samples and correlated their level of expression with the clinical outcome...
  43. ncbi request reprint The HGF/SF antagonist NK4 reverses fibroblast- and HGF-induced prostate tumor growth and angiogenesis in vivo
    Gaynor Davies
    Metastasis Research Group, University Department of Surgery, University of Wales College of Medicine, Cardiff CF14 4XN, Wales, UK
    Int J Cancer 106:348-54. 2003
    ..Finally, our study provides evidence of the therapeutic potential of NK4 in prostate cancer development by antagonising HGF/SF-mediated events...
  44. ncbi request reprint PGF isoforms, PLGF-1 and PGF-2 and the PGF receptor, neuropilin, in human breast cancer: prognostic significance
    Astrid Escudero-Esparza
    Department of Surgery, Cardiff School of Medicine, Cardiff University, Cardiff, UK
    Oncol Rep 23:537-44. 2010
    ..Our study shows that PLGF isoforms PLGF-1 and PGF-2 and indeed their receptor neuopilin, have an aberrant pattern of expression and that high levels of the PLGF-1 and neuropilin are linked to a poor prognosis...
  45. ncbi request reprint Tight junctions and bladder cancer (review)
    Mark D Haynes
    Department of Surgery, Wales College of Medicine, Cardiff University, Heath Park, Cardiff CF14 4XN, UK
    Int J Mol Med 16:3-9. 2005
    ..The purpose of this review is to summarise current understanding on the role and regulation of tight junction function in the normal and diseased bladder...
  46. ncbi request reprint The differential expression of hCNT1 and hENT1 i n breast cancer and the possible impact on breast cancer therapy
    Jane Lane
    School of Medicine, Cardiff University, Cardiff, Wales, United Kingdom
    J Exp Ther Oncol 8:203-10. 2010
    ..The level of expression of CNT1 was closely linked to the cell's responsiveness to chemotherapeutic treatments...
  47. ncbi request reprint Gamma-Linolenic acid regulates the expression and secretion of SPARC in human cancer cells
    Gareth Watkins
    Metastasis and Angiogenesis Research Group, Wales College of Medicine, Cardiff University, Heath Park, Cardiff CF14 4XN, UK
    Prostaglandins Leukot Essent Fatty Acids 72:273-8. 2005
    ..It reduces the secretion of SPARC into surrounding environment, which may contribute to the reduction of cancer cells adhesion to the extracellular matrix and cell motility...
  48. ncbi request reprint PGF isoforms, PLGF-1 and PGF-2, in colorectal cancer and the prognostic significance
    Astrid Escudero-Esparza
    Metastasis and Angiogenesis Research Group, Department of Surgery, Cardiff School of Medicine, Cardiff University, Heath Park, Cardiff, CF14 4XN, UK
    Cancer Genomics Proteomics 6:239-46. 2009
    ..This study examined the expression of PLGF-1 and PGF-2 in human colorectal cancer and how changes in expression may be linked to prognosis of the disease...