Alexander Klein

Summary

Affiliation: Cardiff University
Country: UK

Publications

  1. doi Walking pattern analysis after unilateral 6-OHDA lesion and transplantation of foetal dopaminergic progenitor cells in rats
    Alexander Klein
    Canadian Centre for Behavioural Neuroscience, University of Lethbridge, 4401 University Drive, Lethbridge, Alberta T1K 3M4, Canada
    Behav Brain Res 199:317-25. 2009
  2. doi The use of rodent skilled reaching as a translational model for investigating brain damage and disease
    Alexander Klein
    Brain Repair Group, School of Biosciences, Cardiff University, Cardiff, Wales, UK
    Neurosci Biobehav Rev 36:1030-42. 2012
  3. doi Proximal movements compensate for distal forelimb movement impairments in a reach-to-eat task in Huntington's disease: new insights into motor impairments in a real-world skill
    Alexander Klein
    Brain Repair Group, School of Biosciences, Cardiff University, Cardiff, Wales, UK
    Neurobiol Dis 41:560-9. 2011
  4. doi Dose-dependent loss of motor function after unilateral medial forebrain bundle rotenone lesion in rats: a cautionary note
    Alexander Klein
    Canadian Centre for Behavioural Neuroscience, Department of Neuroscience, University of Lethbridge, Lethbridge, Alberta T1K 3M4, Canada
    Behav Brain Res 222:33-42. 2011
  5. doi Analysis of skilled forelimb movement in rats: the single pellet reaching test and staircase test
    Alexander Klein
    Brain Repair Group, School of Biosciences, Cardiff University, Cardiff, Wales, United Kingdom
    Curr Protoc Neurosci . 2012
  6. doi Three-dimensional motion analysis of postural adjustments during over-ground locomotion in a rat model of Parkinson's disease
    June K Madete
    Cardiff School of Engineering, Cardiff University, Cardiff, Wales, UK
    Behav Brain Res 220:119-25. 2011
  7. doi Profiles of motor and cognitive impairment in the transgenic rat model of Huntington's disease
    Steven A Fielding
    The Brain Repair Group, School of Biosciences, Cardiff University, UK
    Brain Res Bull 88:223-36. 2012
  8. doi Predictable stress versus unpredictable stress: a comparison in a rodent model of stroke
    Fabiola C R Zucchi
    Canadian Centre for Behavioural Neuroscience, University of Lethbridge, 4401 University Drive, Lethbridge, AB, Canada T1K 3M4
    Behav Brain Res 205:67-75. 2009
  9. doi Brain repair in a unilateral rat model of Huntington's disease: new insights into impairment and restoration of forelimb movement patterns
    Alexander Klein
    Brain Repair Group, School of Biosciences, Cardiff University, Cardiff, Wales, UK
    Cell Transplant 22:1735-51. 2013

Collaborators

Detail Information

Publications9

  1. doi Walking pattern analysis after unilateral 6-OHDA lesion and transplantation of foetal dopaminergic progenitor cells in rats
    Alexander Klein
    Canadian Centre for Behavioural Neuroscience, University of Lethbridge, 4401 University Drive, Lethbridge, Alberta T1K 3M4, Canada
    Behav Brain Res 199:317-25. 2009
    ..A full restoration of locomotor gait pattern might require a more complete and organotypic reconstruction of the mesotelencephalic DAergic pathway...
  2. doi The use of rodent skilled reaching as a translational model for investigating brain damage and disease
    Alexander Klein
    Brain Repair Group, School of Biosciences, Cardiff University, Cardiff, Wales, UK
    Neurosci Biobehav Rev 36:1030-42. 2012
    ..The striking similarities between human and rodent reaching movements allow the analysis of the reach-to-eat movement to serve as a powerful tool to generalize preclinical research to clinical conditions...
  3. doi Proximal movements compensate for distal forelimb movement impairments in a reach-to-eat task in Huntington's disease: new insights into motor impairments in a real-world skill
    Alexander Klein
    Brain Repair Group, School of Biosciences, Cardiff University, Cardiff, Wales, UK
    Neurobiol Dis 41:560-9. 2011
    ..The protocol can serve as a useful clinical tool to evaluate innovative therapeutic interventions in HD such as physiotherapy, drug therapy, or functional neurosurgical procedures...
  4. doi Dose-dependent loss of motor function after unilateral medial forebrain bundle rotenone lesion in rats: a cautionary note
    Alexander Klein
    Canadian Centre for Behavioural Neuroscience, Department of Neuroscience, University of Lethbridge, Lethbridge, Alberta T1K 3M4, Canada
    Behav Brain Res 222:33-42. 2011
    ..Furthermore, caution is advised concerning non-specific toxicity of rotenone and vehicle substances in experimental animal models...
  5. doi Analysis of skilled forelimb movement in rats: the single pellet reaching test and staircase test
    Alexander Klein
    Brain Repair Group, School of Biosciences, Cardiff University, Cardiff, Wales, United Kingdom
    Curr Protoc Neurosci . 2012
    ..Both tests have been used extensively to investigate motor deficits and effects of treatment...
  6. doi Three-dimensional motion analysis of postural adjustments during over-ground locomotion in a rat model of Parkinson's disease
    June K Madete
    Cardiff School of Engineering, Cardiff University, Cardiff, Wales, UK
    Behav Brain Res 220:119-25. 2011
    ..Our data demonstrate that marker-based motion capture can provide an effective and simple approach to quantifying postural adjustments for rat models of PD...
  7. doi Profiles of motor and cognitive impairment in the transgenic rat model of Huntington's disease
    Steven A Fielding
    The Brain Repair Group, School of Biosciences, Cardiff University, UK
    Brain Res Bull 88:223-36. 2012
    ....
  8. doi Predictable stress versus unpredictable stress: a comparison in a rodent model of stroke
    Fabiola C R Zucchi
    Canadian Centre for Behavioural Neuroscience, University of Lethbridge, 4401 University Drive, Lethbridge, AB, Canada T1K 3M4
    Behav Brain Res 205:67-75. 2009
    ....
  9. doi Brain repair in a unilateral rat model of Huntington's disease: new insights into impairment and restoration of forelimb movement patterns
    Alexander Klein
    Brain Repair Group, School of Biosciences, Cardiff University, Cardiff, Wales, UK
    Cell Transplant 22:1735-51. 2013
    ....