Alexander Klein

Summary

Affiliation: Cardiff University
Country: UK

Publications

  1. ncbi Walking pattern analysis after unilateral 6-OHDA lesion and transplantation of foetal dopaminergic progenitor cells in rats
    Alexander Klein
    Canadian Centre for Behavioural Neuroscience, University of Lethbridge, 4401 University Drive, Lethbridge, Alberta T1K 3M4, Canada
    Behav Brain Res 199:317-25. 2009
  2. ncbi The use of rodent skilled reaching as a translational model for investigating brain damage and disease
    Alexander Klein
    Brain Repair Group, School of Biosciences, Cardiff University, Cardiff, Wales, UK
    Neurosci Biobehav Rev 36:1030-42. 2012
  3. ncbi Proximal movements compensate for distal forelimb movement impairments in a reach-to-eat task in Huntington's disease: new insights into motor impairments in a real-world skill
    Alexander Klein
    Brain Repair Group, School of Biosciences, Cardiff University, Cardiff, Wales, UK
    Neurobiol Dis 41:560-9. 2011
  4. ncbi Dose-dependent loss of motor function after unilateral medial forebrain bundle rotenone lesion in rats: a cautionary note
    Alexander Klein
    Canadian Centre for Behavioural Neuroscience, Department of Neuroscience, University of Lethbridge, Lethbridge, Alberta T1K 3M4, Canada
    Behav Brain Res 222:33-42. 2011
  5. ncbi Analysis of skilled forelimb movement in rats: the single pellet reaching test and staircase test
    Alexander Klein
    Brain Repair Group, School of Biosciences, Cardiff University, Cardiff, Wales, United Kingdom
    Curr Protoc Neurosci . 2012
  6. ncbi Three-dimensional motion analysis of postural adjustments during over-ground locomotion in a rat model of Parkinson's disease
    June K Madete
    Cardiff School of Engineering, Cardiff University, Cardiff, Wales, UK
    Behav Brain Res 220:119-25. 2011
  7. ncbi Profiles of motor and cognitive impairment in the transgenic rat model of Huntington's disease
    Steven A Fielding
    The Brain Repair Group, School of Biosciences, Cardiff University, UK
    Brain Res Bull 88:223-36. 2012
  8. ncbi Predictable stress versus unpredictable stress: a comparison in a rodent model of stroke
    Fabiola C R Zucchi
    Canadian Centre for Behavioural Neuroscience, University of Lethbridge, 4401 University Drive, Lethbridge, AB, Canada T1K 3M4
    Behav Brain Res 205:67-75. 2009

Collaborators

Detail Information

Publications8

  1. ncbi Walking pattern analysis after unilateral 6-OHDA lesion and transplantation of foetal dopaminergic progenitor cells in rats
    Alexander Klein
    Canadian Centre for Behavioural Neuroscience, University of Lethbridge, 4401 University Drive, Lethbridge, Alberta T1K 3M4, Canada
    Behav Brain Res 199:317-25. 2009
    ..A full restoration of locomotor gait pattern might require a more complete and organotypic reconstruction of the mesotelencephalic DAergic pathway...
  2. ncbi The use of rodent skilled reaching as a translational model for investigating brain damage and disease
    Alexander Klein
    Brain Repair Group, School of Biosciences, Cardiff University, Cardiff, Wales, UK
    Neurosci Biobehav Rev 36:1030-42. 2012
    ..The striking similarities between human and rodent reaching movements allow the analysis of the reach-to-eat movement to serve as a powerful tool to generalize preclinical research to clinical conditions...
  3. ncbi Proximal movements compensate for distal forelimb movement impairments in a reach-to-eat task in Huntington's disease: new insights into motor impairments in a real-world skill
    Alexander Klein
    Brain Repair Group, School of Biosciences, Cardiff University, Cardiff, Wales, UK
    Neurobiol Dis 41:560-9. 2011
    ..The protocol can serve as a useful clinical tool to evaluate innovative therapeutic interventions in HD such as physiotherapy, drug therapy, or functional neurosurgical procedures...
  4. ncbi Dose-dependent loss of motor function after unilateral medial forebrain bundle rotenone lesion in rats: a cautionary note
    Alexander Klein
    Canadian Centre for Behavioural Neuroscience, Department of Neuroscience, University of Lethbridge, Lethbridge, Alberta T1K 3M4, Canada
    Behav Brain Res 222:33-42. 2011
    ..Furthermore, caution is advised concerning non-specific toxicity of rotenone and vehicle substances in experimental animal models...
  5. ncbi Analysis of skilled forelimb movement in rats: the single pellet reaching test and staircase test
    Alexander Klein
    Brain Repair Group, School of Biosciences, Cardiff University, Cardiff, Wales, United Kingdom
    Curr Protoc Neurosci . 2012
    ..Both tests have been used extensively to investigate motor deficits and effects of treatment...
  6. ncbi Three-dimensional motion analysis of postural adjustments during over-ground locomotion in a rat model of Parkinson's disease
    June K Madete
    Cardiff School of Engineering, Cardiff University, Cardiff, Wales, UK
    Behav Brain Res 220:119-25. 2011
    ..Our data demonstrate that marker-based motion capture can provide an effective and simple approach to quantifying postural adjustments for rat models of PD...
  7. ncbi Profiles of motor and cognitive impairment in the transgenic rat model of Huntington's disease
    Steven A Fielding
    The Brain Repair Group, School of Biosciences, Cardiff University, UK
    Brain Res Bull 88:223-36. 2012
    ....
  8. ncbi Predictable stress versus unpredictable stress: a comparison in a rodent model of stroke
    Fabiola C R Zucchi
    Canadian Centre for Behavioural Neuroscience, University of Lethbridge, 4401 University Drive, Lethbridge, AB, Canada T1K 3M4
    Behav Brain Res 205:67-75. 2009
    ....