Peter Holmans


Affiliation: Cardiff University
Country: UK


  1. Holmans P, Stone T. Using Genomic Data to Find Disease-Modifying Loci in Huntington's Disease (HD). Methods Mol Biol. 2018;1780:443-461 pubmed publisher
    ..The chapter ends with a short overview of future prospects for detecting genetic modifiers of HD. ..
  2. Holmans P, Green E, Pahwa J, Ferreira M, PURCELL S, Sklar P, et al. Gene ontology analysis of GWA study data sets provides insights into the biology of bipolar disorder. Am J Hum Genet. 2009;85:13-24 pubmed publisher
    ..The method was also applied to a meta-analysis of bipolar disorder, and it implicated the modulation of transcription and cellular activity, including that which occurs via hormonal action, as an important player in pathogenesis. ..
  3. Bowles K, Stone T, Holmans P, Allen N, Dunnett S, Jones L. SMAD transcription factors are altered in cell models of HD and regulate HTT expression. Cell Signal. 2017;31:1-14 pubmed publisher
    ..The dysregulation of HTT expression may contribute to the altered transcriptional phenotype observed in HD. ..