Anthony J Hayes

Summary

Affiliation: Cardiff University
Country: UK

Publications

  1. pmc PPARdelta status and mismatch repair mediated neoplasia in the mouse intestine
    Karen R Reed
    Cardiff School of Biosciences, Cardiff University, Museum Avenue, Cardiff CF103US, UK
    BMC Cancer 6:113. 2006
  2. ncbi request reprint Macromolecular organization and in vitro growth characteristics of scaffold-free neocartilage grafts
    Anthony J Hayes
    Connective Tissue Biology Laboratory and Cardiff Institute of Tissue Engineering and Repair, Cardiff School of Biosciences, Cardiff University, Cardiff CF10 3US, Wales, UK
    J Histochem Cytochem 55:853-66. 2007
  3. doi request reprint Antibodies and immunohistochemistry in extracellular matrix research
    Anthony J Hayes
    Connective Tissue Biology Laboratory and Cardiff Institute of Tissue Engineering and Repair, Cardiff School of Biosciences, Cardiff University, Cardiff, UK
    Methods 45:10-21. 2008
  4. doi request reprint Immunochemical localization of keratan sulfate proteoglycans in cornea, sclera, and limbus using a keratanase-generated neoepitope monoclonal antibody
    Saeed Akhtar
    School of Optometry and Vision Sciences, Cardiff University, Cardiff, United Kingdom
    Invest Ophthalmol Vis Sci 49:2424-31. 2008
  5. ncbi request reprint Collagen fibrillogenesis in the development of the annulus fibrosus of the intervertebral disc
    Anthony J Hayes
    Connective Tissue Biology Laboratory and Cardiff Institute of Tissue Engineering and Repair, Cardiff School of Biosciences, Cardiff University, Cardiff CF10 3US, Wales, UK
    Eur Cell Mater 22:226-41. 2011
  6. doi request reprint A 'Sleeping Trojan Horse' which transports metal ions into cells, localises in nucleoli, and has potential for bimodal fluorescence/PET imaging
    Flora L Thorp-Greenwood
    Department of Chemistry, Cardiff University, Cardiff, Cymru Wales, UK CF10 3AT
    Chem Commun (Camb) 47:3096-8. 2011
  7. doi request reprint Actin and type I collagen propeptide distribution in the developing chick cornea
    Claire Gealy
    Connective Tissue Biology Laboratories, School of Biosciences, Cardiff University, Cardiff, United Kingdom
    Invest Ophthalmol Vis Sci 50:1653-8. 2009
  8. pmc Expression of glycosaminoglycan epitopes during zebrafish skeletogenesis
    Anthony J Hayes
    Connective Tissue Biology Laboratory, Cardiff School of Biosciences and Cardiff Institute of Tissue Engineering and Repair, Cardiff University, Cardiff, United Kingdom
    Dev Dyn 242:778-89. 2013
  9. doi request reprint Mitochondria-derived organelles in the diplomonad fish parasite Spironucleus vortens
    Coralie O M Millet
    School of Biosciences, Cardiff University, Cardiff, Wales CF10 3AT, UK
    Exp Parasitol 135:262-73. 2013
  10. pmc Spinal Deformity in Aged Zebrafish Is Accompanied by Degenerative Changes to Their Vertebrae that Resemble Osteoarthritis
    Anthony J Hayes
    Pathophysiology and Repair, Cardiff School of Biosciences, Cardiff University, Cardiff, Wales, United Kingdom
    PLoS ONE 8:e75787. 2013

Collaborators

Detail Information

Publications20

  1. pmc PPARdelta status and mismatch repair mediated neoplasia in the mouse intestine
    Karen R Reed
    Cardiff School of Biosciences, Cardiff University, Museum Avenue, Cardiff CF103US, UK
    BMC Cancer 6:113. 2006
    ..To further investigate the PPARdelta dependency of intestinal tumourigenesis, we have analysed the consequences of PPARdelta deficiency upon intestinal neoplasia occurring in mice with impaired mismatch DNA repair...
  2. ncbi request reprint Macromolecular organization and in vitro growth characteristics of scaffold-free neocartilage grafts
    Anthony J Hayes
    Connective Tissue Biology Laboratory and Cardiff Institute of Tissue Engineering and Repair, Cardiff School of Biosciences, Cardiff University, Cardiff CF10 3US, Wales, UK
    J Histochem Cytochem 55:853-66. 2007
    ....
  3. doi request reprint Antibodies and immunohistochemistry in extracellular matrix research
    Anthony J Hayes
    Connective Tissue Biology Laboratory and Cardiff Institute of Tissue Engineering and Repair, Cardiff School of Biosciences, Cardiff University, Cardiff, UK
    Methods 45:10-21. 2008
    ..These technologies can also be used to quantify signal intensities and thereby facilitate numerical computation of image data...
  4. doi request reprint Immunochemical localization of keratan sulfate proteoglycans in cornea, sclera, and limbus using a keratanase-generated neoepitope monoclonal antibody
    Saeed Akhtar
    School of Optometry and Vision Sciences, Cardiff University, Cardiff, United Kingdom
    Invest Ophthalmol Vis Sci 49:2424-31. 2008
    ..To evaluate the use of neoepitope monoclonal antibody BKS-1, which recognizes keratanase-generated keratan sulfate (KS) stubs on keratan sulfate proteoglycans in human cornea, limbus, and sclera...
  5. ncbi request reprint Collagen fibrillogenesis in the development of the annulus fibrosus of the intervertebral disc
    Anthony J Hayes
    Connective Tissue Biology Laboratory and Cardiff Institute of Tissue Engineering and Repair, Cardiff School of Biosciences, Cardiff University, Cardiff CF10 3US, Wales, UK
    Eur Cell Mater 22:226-41. 2011
    ..With the exception of keratocan, the other SLRPs appear associated more with cartilage development within the vertebral column, but all become more prominent within the disc during its growth and differentiation...
  6. doi request reprint A 'Sleeping Trojan Horse' which transports metal ions into cells, localises in nucleoli, and has potential for bimodal fluorescence/PET imaging
    Flora L Thorp-Greenwood
    Department of Chemistry, Cardiff University, Cardiff, Cymru Wales, UK CF10 3AT
    Chem Commun (Camb) 47:3096-8. 2011
    ..The luminescence of the vessel and its copper binding ability suggest potential as a bimodal fluorescence/PET imaging agent...
  7. doi request reprint Actin and type I collagen propeptide distribution in the developing chick cornea
    Claire Gealy
    Connective Tissue Biology Laboratories, School of Biosciences, Cardiff University, Cardiff, United Kingdom
    Invest Ophthalmol Vis Sci 50:1653-8. 2009
    ..To determine the organization of actin filaments and distribution of type I procollagen during the development of the chick corneal stroma...
  8. pmc Expression of glycosaminoglycan epitopes during zebrafish skeletogenesis
    Anthony J Hayes
    Connective Tissue Biology Laboratory, Cardiff School of Biosciences and Cardiff Institute of Tissue Engineering and Repair, Cardiff University, Cardiff, United Kingdom
    Dev Dyn 242:778-89. 2013
    ....
  9. doi request reprint Mitochondria-derived organelles in the diplomonad fish parasite Spironucleus vortens
    Coralie O M Millet
    School of Biosciences, Cardiff University, Cardiff, Wales CF10 3AT, UK
    Exp Parasitol 135:262-73. 2013
    ..vortens may necessitate more complex intracellular compartmentation of redox reactions than previously recognized. Control of infection requires biochemical characterization of redox-related organelles...
  10. pmc Spinal Deformity in Aged Zebrafish Is Accompanied by Degenerative Changes to Their Vertebrae that Resemble Osteoarthritis
    Anthony J Hayes
    Pathophysiology and Repair, Cardiff School of Biosciences, Cardiff University, Cardiff, Wales, United Kingdom
    PLoS ONE 8:e75787. 2013
    ..In summary, these observations raise the prospect that zebrafish, in addition to modelling skeletal development, may have utility in modelling age-related degenerative changes that affect the skeleton during senescence. ..
  11. pmc Chondroitin sulfate sulfation motifs as putative biomarkers for isolation of articular cartilage progenitor cells
    Anthony J Hayes
    Connective Tissue Biology Laboratory and Cardiff Institute of Tissue Engineering and Repair, Cardiff School of Biosciences, Cardiff University, Cardiff CF10 3US, Wales, United Kingdom
    J Histochem Cytochem 56:125-38. 2008
    ....
  12. ncbi request reprint Disassembly of the vimentin cytoskeleton disrupts articular cartilage chondrocyte homeostasis
    Emma J Blain
    Connective Tissue Biology Laboratories, Biomedical Sciences Building, School of Biosciences, Cardiff University, Museum Avenue, Cardiff, CF10 3US, Wales, UK
    Matrix Biol 25:398-408. 2006
    ....
  13. ncbi request reprint The response of foetal annulus fibrosus cells to growth factors: modulation of matrix synthesis by TGF-β1 and IGF-1
    Anthony J Hayes
    School of Biosciences, Cardiff University, Biomedical Sciences Building, Museum Avenue, PO Box 911, Cardiff CF10 3AX, UK
    Histochem Cell Biol 136:163-75. 2011
    ..We show a potential role for TGF-β1 in pushing cells towards a fibrocartilaginous phenotype, with possible complementary effects of IGF-1...
  14. ncbi request reprint Differential expression of the keratan sulphate proteoglycan, keratocan, during chick corneal embryogenesis
    E Claire Gealy
    Connective Tissue Biology Laboratories, School of Biosciences, Cardiff University, Museum Avenue, Cardiff, CF10 3US, Wales, UK
    Histochem Cell Biol 128:551-5. 2007
    ..It undergoes a striking reorganisation of structure and distribution consistent with a role in relation to stromal compaction and corneal transparency...
  15. ncbi request reprint Confocal microscopy demonstrates association of LTBP-2 in fibrillin-1 microfibrils and colocalisation with perlecan in the disc cell pericellular matrix
    Anthony J Hayes
    Confocal Microscopy Unit, Preclinical Building, Cardiff School of Biosciences, Cardiff University, Cardiff CF10 3AX, Wales, UK
    Tissue Cell 46:185-97. 2014
    ....
  16. doi request reprint Comparative immunolocalisation of fibrillin-1 and perlecan in the human foetal, and HS-deficient hspg2 exon 3 null mutant mouse intervertebral disc
    Anthony J Hayes
    Confocal Microscopy Unit, Cardiff School of Biosciences, Cardiff University, Cardiff CF10 3US, Wales, UK
    Histochem Cell Biol 139:1-11. 2013
    ..The ability of fibrillin-1 to sequester TGF-β a well-known anabolic growth factor in the IVD also suggests potential roles in disc development and/or remodelling...
  17. doi request reprint Suppression of leukocyte infiltration and cartilage degradation by selective inhibition of pre-B cell colony-enhancing factor/visfatin/nicotinamide phosphoribosyltransferase: Apo866-mediated therapy in human fibroblasts and murine collagen-induced arthrit
    Laura Evans
    Cardiff University School of Medicine, Cardiff, UK
    Arthritis Rheum 63:1866-77. 2011
    ....
  18. ncbi request reprint Therapeutic targeting of IL-6 trans signaling counteracts STAT3 control of experimental inflammatory arthritis
    Mari A Nowell
    Department of Medical Biochemistry and Immunology, School of Medicine, Cardiff University, Cardiff, Wales, United Kingdom
    J Immunol 182:613-22. 2009
    ....
  19. doi request reprint Uptake and localisation of rhenium fac-tricarbonyl polypyridyls in fluorescent cell imaging experiments
    Vanesa Fernández-Moreira
    School of Chemistry, Cardiff University, Cardiff, Wales, UK CF10 3AT
    Org Biomol Chem 8:3888-901. 2010
    ..The patterns of uptake and localisation are correlated with structural and electronic features of the complexes in an attempt to establish ground-rules for the design and application of rhenium complexes in imaging of eukaryotes...
  20. doi request reprint Perlecan, the "jack of all trades" proteoglycan of cartilaginous weight-bearing connective tissues
    James Melrose
    Raymond Purves Research Laboratories, Institute of Bone and Joint Research, Kolling Institute of Medical Research, University of Sydney, Royal North Shore Hospital, St Leonards, NSW, Australia
    Bioessays 30:457-69. 2008
    ....