R J Errington

Summary

Affiliation: Cardiff University
Country: UK

Publications

  1. pmc A transfer function approach to measuring cell inheritance
    Paul Rees
    Centre for Nanohealth, School of Engineering, Swansea University, Swansea, SA2 8PP, UK
    BMC Syst Biol 5:31. 2011
  2. ncbi request reprint Advanced microscopy solutions for monitoring the kinetics and dynamics of drug-DNA targeting in living cells
    R J Errington
    Department of Medical Biochemistry and Immunology, University of Wales College of Medicine, Cardiff, CF14 4XN, UK
    Adv Drug Deliv Rev 57:153-67. 2005
  3. ncbi request reprint Multiple pathways in the trafficking and assembly of connexin 26, 32 and 43 into gap junction intercellular communication channels
    P E Martin
    Department of Medical Biochemistry, University of Wales College of Medicine, Heath Park, Cardiff CF14 4XN, UK
    J Cell Sci 114:3845-55. 2001
  4. ncbi request reprint Characteristics of a novel deep red/infrared fluorescent cell-permeant DNA probe, DRAQ5, in intact human cells analyzed by flow cytometry, confocal and multiphoton microscopy
    P J Smith
    Department of Pathology, University of Wales College of Medicine, Cardiff, United Kingdom
    Cytometry 40:280-91. 2000
  5. ncbi request reprint Gap junction assembly: multiple connexin fluorophores identify complex trafficking pathways
    P E Martin
    Wales Heart Research Institute and Department of Medical Biochemistry, University of Wales College of Medicine, Cardiff, UK
    Cell Commun Adhes 8:243-8. 2001
  6. pmc Tracking the cell cycle origins for escape from topotecan action by breast cancer cells
    G P Feeney
    Department of Pathalogy, University of Wales College of Medicine, Cardiff, UK
    Br J Cancer 88:1310-7. 2003
  7. ncbi request reprint Technique for measurement of fluorescence lifetime by use of stroboscopic excitation and continuous-wave detection
    D R Matthews
    School of Physics and Astronomy, Cardiff University, 5 The Parade, Cardiff CF24 3YB, UK
    Appl Opt 45:2115-23. 2006
  8. ncbi request reprint Cytomics and drug development
    Paul J Smith
    Department of Pathology, Wales College of Medicine, Cardiff University, United Kingdom
    Cytometry A 71:349-51. 2007
  9. ncbi request reprint A coupled drug kinetics-cell cycle model to analyse the response of human cells to intervention by topotecan
    M J Chappell
    School of Engineering, University of Warwick, Coventry, UK
    Comput Methods Programs Biomed 89:169-78. 2008

Collaborators

Detail Information

Publications9

  1. pmc A transfer function approach to measuring cell inheritance
    Paul Rees
    Centre for Nanohealth, School of Engineering, Swansea University, Swansea, SA2 8PP, UK
    BMC Syst Biol 5:31. 2011
    ....
  2. ncbi request reprint Advanced microscopy solutions for monitoring the kinetics and dynamics of drug-DNA targeting in living cells
    R J Errington
    Department of Medical Biochemistry and Immunology, University of Wales College of Medicine, Cardiff, CF14 4XN, UK
    Adv Drug Deliv Rev 57:153-67. 2005
    ..Finally, we discuss the future perspectives on introducing these modular kinetic assays in the high-content screening arena and the interlinking of the consequences of drug-target interactions with cellular stress responses...
  3. ncbi request reprint Multiple pathways in the trafficking and assembly of connexin 26, 32 and 43 into gap junction intercellular communication channels
    P E Martin
    Department of Medical Biochemistry, University of Wales College of Medicine, Heath Park, Cardiff CF14 4XN, UK
    J Cell Sci 114:3845-55. 2001
    ....
  4. ncbi request reprint Characteristics of a novel deep red/infrared fluorescent cell-permeant DNA probe, DRAQ5, in intact human cells analyzed by flow cytometry, confocal and multiphoton microscopy
    P J Smith
    Department of Pathology, University of Wales College of Medicine, Cardiff, United Kingdom
    Cytometry 40:280-91. 2000
    ..We describe here the spectral characteristics and applications of this synthetic compound, particularly in relation to cytometric analysis of the cell cycle...
  5. ncbi request reprint Gap junction assembly: multiple connexin fluorophores identify complex trafficking pathways
    P E Martin
    Wales Heart Research Institute and Department of Medical Biochemistry, University of Wales College of Medicine, Cardiff, UK
    Cell Commun Adhes 8:243-8. 2001
    ..The results indicate that multiple intracellular connexin trafficking routes exist and provide a further mechanism for regulating the connexin composition of gap junctions and thus specificity in intercellular signalling...
  6. pmc Tracking the cell cycle origins for escape from topotecan action by breast cancer cells
    G P Feeney
    Department of Pathalogy, University of Wales College of Medicine, Cardiff, UK
    Br J Cancer 88:1310-7. 2003
    ..31 microM). Overall, topotecan differentially targeted G1-, S- and G2-phase cells, but many G2 cells were resistant to topotecan, presenting a clear route for cell cycle-mediated drug resistance...
  7. ncbi request reprint Technique for measurement of fluorescence lifetime by use of stroboscopic excitation and continuous-wave detection
    D R Matthews
    School of Physics and Astronomy, Cardiff University, 5 The Parade, Cardiff CF24 3YB, UK
    Appl Opt 45:2115-23. 2006
    ..An experimental demonstration of the technique that uses a cuvette-based analysis of a carbocyanine dye and for which the excitation source is a 650 nm wavelength, self-pulsing AlGaInP laser diode is compared with the model...
  8. ncbi request reprint Cytomics and drug development
    Paul J Smith
    Department of Pathology, Wales College of Medicine, Cardiff University, United Kingdom
    Cytometry A 71:349-51. 2007
  9. ncbi request reprint A coupled drug kinetics-cell cycle model to analyse the response of human cells to intervention by topotecan
    M J Chappell
    School of Engineering, University of Warwick, Coventry, UK
    Comput Methods Programs Biomed 89:169-78. 2008
    ..The model is compared to experimental in vitro cell cycle response data (comprising single cell descriptors for molecular and behavioural events), showing good qualitative agreement for a range of TPT dose levels...