R Eccles

Summary

Affiliation: Cardiff University
Country: UK

Publications

  1. doi request reprint Efficacy of inferior turbinate coblation for treatment of nasal obstruction
    S E J Farmer
    Common Cold Centre, Cardiff School of Biosciences, Cardiff University, Cardiff, Wales, UK
    J Laryngol Otol 123:309-14. 2009
  2. doi request reprint Is the common cold a clinical entity or a cultural concept?
    R Eccles
    Cardiff School of Biosciences, Cardiff University, UK
    Rhinology 51:3-8. 2013
  3. pmc Mechanical induction of cough in Idiopathic Pulmonary Fibrosis
    Richard M Jones
    Respiratory Unit, Morriston Hospital, Heol Maes Eglwys, Swansea, SA6 6NL, UK
    Cough 7:2. 2011
  4. ncbi request reprint Mechanisms of the symptoms of rhinosinusitis
    R Eccles
    Common Cold Centre and Healthcare Clinical Trials Cardiff School of Biosciences, Cardiff University, United Kingdom
    Rhinology 49:131-8. 2011
  5. ncbi request reprint Cough induced by mechanical stimulation of the upper airway in humans
    Patrick Lee
    Common Cold Centre, Cardiff School of Biosciences, Cardiff University, Cardiff UK
    Acta Otolaryngol 124:720-5. 2004
  6. ncbi request reprint Understanding the symptoms of the common cold and influenza
    Ron Eccles
    Common Cold Centre, Cardiff School of Biosciences, Cardiff School of Biosciences, Cardiff University, Cardiff, UK
    Lancet Infect Dis 5:718-25. 2005
  7. ncbi request reprint Mechanisms of the placebo effect of sweet cough syrups
    Ronald Eccles
    Common Cold Centre, Cardiff School of Biosciences, Cardiff University, Cardiff CF10 3US, UK
    Respir Physiol Neurobiol 152:340-8. 2006
  8. ncbi request reprint A guide to practical aspects of measurement of human nasal airflow by rhinomanometry
    R Eccles
    Common Cold Centre and Healthcare Clinical Trials Cardiff School of Biosciences, Cardiff University, United Kingdom
    Rhinology 49:2-10. 2011
  9. ncbi request reprint Efficacy and safety of over-the-counter analgesics in the treatment of common cold and flu
    R Eccles
    Common Cold Centre, Cardiff School of Biosciences, Cardiff University, Cardiff, UK
    J Clin Pharm Ther 31:309-19. 2006
  10. pmc Substitution of phenylephrine for pseudoephedrine as a nasal decongeststant. An illogical way to control methamphetamine abuse
    Ronald Eccles
    Common Cold Centre and Healthcare Clinical Trials, Cardiff School of Biosciences, Cardiff University, Cardiff, UK
    Br J Clin Pharmacol 63:10-4. 2007

Collaborators

Detail Information

Publications58

  1. doi request reprint Efficacy of inferior turbinate coblation for treatment of nasal obstruction
    S E J Farmer
    Common Cold Centre, Cardiff School of Biosciences, Cardiff University, Cardiff, Wales, UK
    J Laryngol Otol 123:309-14. 2009
    ..To determine the efficacy of inferior turbinate coblation for the treatment of nasal obstruction...
  2. doi request reprint Is the common cold a clinical entity or a cultural concept?
    R Eccles
    Cardiff School of Biosciences, Cardiff University, UK
    Rhinology 51:3-8. 2013
    ....
  3. pmc Mechanical induction of cough in Idiopathic Pulmonary Fibrosis
    Richard M Jones
    Respiratory Unit, Morriston Hospital, Heol Maes Eglwys, Swansea, SA6 6NL, UK
    Cough 7:2. 2011
    ..abstract:..
  4. ncbi request reprint Mechanisms of the symptoms of rhinosinusitis
    R Eccles
    Common Cold Centre and Healthcare Clinical Trials Cardiff School of Biosciences, Cardiff University, United Kingdom
    Rhinology 49:131-8. 2011
    ..The mechanism of unilateral nasal obstruction with rhinosinusitis is discussed...
  5. ncbi request reprint Cough induced by mechanical stimulation of the upper airway in humans
    Patrick Lee
    Common Cold Centre, Cardiff School of Biosciences, Cardiff University, Cardiff UK
    Acta Otolaryngol 124:720-5. 2004
    ..We also wished to investigate if there was any difference in cough sensitivity between healthy subjects and those with acute upper respiratory tract infection (URTI)...
  6. ncbi request reprint Understanding the symptoms of the common cold and influenza
    Ron Eccles
    Common Cold Centre, Cardiff School of Biosciences, Cardiff School of Biosciences, Cardiff University, Cardiff, UK
    Lancet Infect Dis 5:718-25. 2005
    ..The mechanisms of symptoms of sore throat, rhinorrhoea, sneezing, nasal congestion, cough, watery eyes, and sinus pain are discussed, since these mechanisms are not dealt with in any detail in standard medical textbooks...
  7. ncbi request reprint Mechanisms of the placebo effect of sweet cough syrups
    Ronald Eccles
    Common Cold Centre, Cardiff School of Biosciences, Cardiff University, Cardiff CF10 3US, UK
    Respir Physiol Neurobiol 152:340-8. 2006
    ..The idea is developed that a sweet taste may modulate cough at the level of the nucleus tractus solitarius, possibly by influencing the production of endogenous opioids...
  8. ncbi request reprint A guide to practical aspects of measurement of human nasal airflow by rhinomanometry
    R Eccles
    Common Cold Centre and Healthcare Clinical Trials Cardiff School of Biosciences, Cardiff University, United Kingdom
    Rhinology 49:2-10. 2011
    ....
  9. ncbi request reprint Efficacy and safety of over-the-counter analgesics in the treatment of common cold and flu
    R Eccles
    Common Cold Centre, Cardiff School of Biosciences, Cardiff University, Cardiff, UK
    J Clin Pharm Ther 31:309-19. 2006
    ..The aim of this review was to determine the safety and efficacy of the analgesics, aspirin, paracetamol and aspirin for the treatment of colds and flu...
  10. pmc Substitution of phenylephrine for pseudoephedrine as a nasal decongeststant. An illogical way to control methamphetamine abuse
    Ronald Eccles
    Common Cold Centre and Healthcare Clinical Trials, Cardiff School of Biosciences, Cardiff University, Cardiff, UK
    Br J Clin Pharmacol 63:10-4. 2007
    ..Restrictions on sales of PDE to the public may not reduce the problems associated with methamphetamine abuse...
  11. ncbi request reprint The power of the placebo
    Ron Eccles
    Common Cold Centre, Cardiff School of Biosciences, Cardiff University, Cardiff CF10 3US, UK
    Curr Allergy Asthma Rep 7:100-4. 2007
    ..An understanding of the placebo and nocebo effects is important for general allergy practice, and harnessing the power of the true placebo effect is a major challenge to modern medicine...
  12. doi request reprint The nasal decongestant effect of xylometazoline in the common cold
    Ronald Eccles
    Common Cold Centre and Healthcare Clinical Trials, Cardiff University, Cardiff, United Kingdom
    Am J Rhinol 22:491-6. 2008
    ..The purpose of this study was to characterize objectively and subjectively the decongestant and additional effects of xylometazoline in the common cold...
  13. doi request reprint Importance of placebo effect in cough clinical trials
    Ron Eccles
    Common Cold Centre, Cardiff School of Biosciences, Cardiff University, Museum Avenue, Cardiff, CF10 3AX, Wales, UK
    Lung 188:S53-61. 2010
    ..The placebo effect in clinical trials may be controlled by use of a crossover design, where feasible, and the changes in the magnitude of the placebo effect in this study design are discussed...
  14. doi request reprint Effects of intranasal xylometazoline, alone or in combination with ipratropium, in patients with common cold
    Ronald Eccles
    Common Cold Centre and Healthcare Clinical Trials, Cardiff School of Biosciences, Cardiff University, Cardiff, UK
    Curr Med Res Opin 26:889-99. 2010
    ..However, most studies have investigated its clinical efficacy in healthy patients and few have included patients with common cold...
  15. ncbi request reprint Effects of acetylsalicylic acid on sore throat pain and other pain symptoms associated with acute upper respiratory tract infection
    Ron Eccles
    Common Cold Centre, Cardiff University, UK
    Pain Med 4:118-24. 2003
    ..The objective of this study was to investigate the efficacy and safety of ASA for the treatment of sore throat pain associated with URTI...
  16. ncbi request reprint Acute cooling of the body surface and the common cold
    R Eccles
    Common Cold Centre, Cardiff School of Biosciences, Cardiff University, United Kingdom
    Rhinology 40:109-14. 2002
    ....
  17. ncbi request reprint The powerful placebo in cough studies?
    R Eccles
    Common Cold Centre, Cardiff School of Biosciences, Cardiff University, Cardiff, CF10 3US, UK
    Pulm Pharmacol Ther 15:303-8. 2002
    ..With active pharmacological ingredients contributing only 15% to the effects of cough treatment it seems reasonable to conduct more research on the other components of treatment such as placebo...
  18. ncbi request reprint An explanation for the seasonality of acute upper respiratory tract viral infections
    R Eccles
    Common Cold Centre, Cardiff School of Biosciences, Cardiff University, UK
    Acta Otolaryngol 122:183-91. 2002
    ..A case is also made to suggest that warming of the nasal airway during fever and nasal congestion may help to resolve a current URTI...
  19. ncbi request reprint Nasal airflow in health and disease
    R Eccles
    Common Cold Centre, Cardiff School of Biosciences, Cardiff University, UK
    Acta Otolaryngol 120:580-95. 2000
    ....
  20. ncbi request reprint The nasal cycle in respiratory defence
    R B Eccles
    Common Cold and Nasal Research Centre, Cardiff School of Biosciences, Cardiff University, United Kingdom
    Acta Otorhinolaryngol Belg 54:281-6. 2000
    ....
  21. ncbi request reprint Menthol: effects on nasal sensation of airflow and the drive to breathe
    Ronald Eccles
    Common Cold and Nasal Research Centre, Cardiff School of Biosciences, Biomedical Building, Museum Avenue, PO Box 911, Cardiff CF10 3US, UK
    Curr Allergy Asthma Rep 3:210-4. 2003
    ....
  22. ncbi request reprint Changes in the amplitude of the nasal cycle associated with symptoms of acute upper respiratory tract infection
    R Eccles
    Common Cold and Nasal Research Centre, Univeristy of Wales College of Cardiff, UK
    Acta Otolaryngol 116:77-81. 1996
    ....
  23. ncbi request reprint Do chronic changes in nasal airflow have any physiological or pathological effect on the nose and paranasal sinuses? A systematic review
    J Boyce
    Common Cold Centre, Cardiff School of Biosciences, Cardiff University, Cardiff, UK
    Clin Otolaryngol 31:15-9. 2006
    ..Such studies provide evidence that reduced nasal airflow causes no significant nasal disease. . There is no convincing evidence that a reduction in nasal airflow is a causative factor for rhinitis or sinusitis...
  24. doi request reprint Normal nasal patency: problems in obtaining standard reference values for the surgeon
    M Moore
    Common Cold Centre, Cardiff University, Wales, UK
    J Laryngol Otol 126:563-9. 2012
    ..Rather than classify populations according to unscientific categories such as race, anthropometric measures such as the nasal index are proposed...
  25. ncbi request reprint Effect of submucosal diathermy to the inferior turbinates on unilateral and total nasal airflow in patients with rhinitis
    S M Quine
    Department of Otolaryngology, University Hospital of Wales, Cardiff, UK
    Acta Otolaryngol 119:911-5. 1999
    ..The importance of considering the nose as two separate airways in the evaluation of nasal treatments is emphasized...
  26. ncbi request reprint Efficacy of a paracetamol-pseudoephedrine combination for treatment of nasal congestion and pain-related symptoms in upper respiratory tract infection
    R Eccles
    Common Cold Centre, Cardiff University, Cardiff, UK
    Curr Med Res Opin 22:2411-8. 2006
    ..This study compared the efficacy of 1000 mg of paracetamol combined with 60 mg of pseudoephedrine, with that of either paracetamol or pseudoephedrine alone and placebo for the treatment of symptomatic URTI...
  27. ncbi request reprint Nasal congestion: mechanisms, measurement and medications. Core information for the clinician
    S S Davis
    Common Cold Centre, Cardiff School of Biosciences, Cardiff University, Cardiff, UK
    Clin Otolaryngol Allied Sci 29:659-66. 2004
    ....
  28. ncbi request reprint The relationship between nasal index and nasal airway resistance, and response to a topical decongestant
    N M Doddi
    Common Cold Centre and Healthcare Clinical Trials, Cardiff School of Biosciences, Cardiff University, Cardiff, UK
    Rhinology 49:583-6. 2011
    ..02). The absence of any physiological differences between the different nose types may be due to acclimatisation of participants to the area of recruitment...
  29. ncbi request reprint Chronic inferior turbinate enlargement and the implications for surgical intervention
    S E J Farmer
    Common Cold Centre, Cardiff School of Biosciences, Cardiff University, Cardiff, United Kingdom
    Rhinology 44:234-8. 2006
    ..The underlying pathology of turbinate enlargement has important implications for the surgical management of nasal obstruction...
  30. doi request reprint Coblation® inferior turbinate reduction: a long-term follow-up with subjective and objective assessment
    S C Leong
    Common Cold Centre and Healthcare Clinical Trials, Cardiff School of Biosciences, Cardiff University, and Deaprtment of Otolaryngology Head and Neck Surgery, University Hospital of Wales, Cardiff, Wales, UK
    Rhinology 48:108-12. 2010
    ..Although there was improvement in the subjective assessment of nasal obstruction, this did not achieve statistical significance...
  31. ncbi request reprint Assessment of subjective scales for selection of patients for nasal septal surgery
    J M Boyce
    Common Cold Centre, Cardiff School of Biosciences, Cardiff University, Cardiff, UK
    Clin Otolaryngol 31:297-302. 2006
    ..To investigate the use of subjective measures to assist the surgeon in patient selection for septal surgery...
  32. ncbi request reprint Postnasal drip syndrome. Two hundred years of controversy between UK and USA
    A Sanu
    Common Cold Centre and Healthcare Clinical Trials, Cardiff School of Biosciences, Cardiff University, Cardiff, UK
    Rhinology 46:86-91. 2008
    ..Current research on treating excessive airway mucus in the lower airways may be applicable to PNDS...
  33. ncbi request reprint Evidence for correlation of objective and subjective measures of nasal airflow in patients with common cold
    J D Clarke
    Common Cold Centre, Cardiff School of Biosciences, Cardiff University, Cardiff, UK
    Clin Otolaryngol 30:35-8. 2005
    ..To utilize posterior rhinomanometry and conductance, as units of measurement, to further investigate the relationship between subjective and objective measures of nasal airflow...
  34. ncbi request reprint The use of nasal spirometry as an objective measure of nasal septal deviation and the effectiveness of septal surgery
    P J Cuddihy
    Common Cold Centre, Cardiff School of Biosciences, Cardiff University, Cardiff, UK
    Clin Otolaryngol Allied Sci 28:325-30. 2003
    ..01), and with patient subjective symptom assessment r= 0.94 (P < 0.01) preoperatively and r= 0.51 (P < 0.01) postoperatively. The findings indicate that nasal spirometry may be useful in patient selection for septal surgery...
  35. ncbi request reprint [Cough induction by high-frequency chest percussion in healthy volunteers and patients with common cold]
    P C L Lee
    Common Cold Centre, Cardiff School of Biosciences, Cardiff University, Cardiff CF10 3US, UK
    Respir Med 98:771-6. 2004
    ..The aim of this study was to determine if cough can be induced by high-frequency chest percussion in healthy subjects and in patients with acute upper respiratory tract infection (URTI)...
  36. doi request reprint Objective evidence for the efficacy of surgical management of the deviated septum as a treatment for chronic nasal obstruction: a systematic review
    M Moore
    Common Cold Centre, Cardiff University, Cardiff, UK
    Clin Otolaryngol 36:106-13. 2011
    ..Nasal septal surgery is a common procedure, but there are concerns that the benefits of this surgery are mainly cosmetic...
  37. ncbi request reprint A clinical study to evaluate the efficacy of the antihistamine doxylamine succinate in the relief of runny nose and sneezing associated with upper respiratory tract infection
    R Eccles
    Common Cold and Nasal Research Centre, University of Wales, Cardiff, UK
    J Pharm Pharmacol 47:990-3. 1995
    ..Of the expected side-effects, 13.3% of doxylamine-treated patients reported drowsiness. The incidence of sedative effects was lower than has been reported for other commonly used first-generation antihistamines...
  38. ncbi request reprint The use of nasal spirometry for the assessment of unilateral nasal obstruction associated with changes in posture in healthy subjects and subjects with upper respiratory tract infection
    P J Cuddihy
    Common Cold Centre, Cardiff School of Biosciences, Cardiff University, Cardiff, UK
    Clin Otolaryngol Allied Sci 28:108-11. 2003
    ..The results illustrate the incidence of complete unilateral nasal obstruction associated with URTI when lying flat and demonstrate the usefulness of nasal spirometry in studying nasal airflow partitioning in health and disease...
  39. ncbi request reprint Cough induced by airway vibration as a model of airway hyperreactivity in patients with acute upper respiratory tract infection
    R Eccles
    Common Cold Centre, Cardiff School of Biosciences, Cardiff University, Cardiff CF10 3US, UK
    Pulm Pharmacol Ther 17:337-42. 2004
    ..The airway vibration model of cough may have some advantages over inhaled tussigens as the stimulus is easily controlled and the method is safe for use in children...
  40. ncbi request reprint The effects of a hot drink on nasal airflow and symptoms of common cold and flu
    A Sanu
    Common Cold Centre and Healthcare Clinical Trials, Cardiff School of Biosciences, Cardiff University, Cardiff, United Kingdom
    Rhinology 46:271-5. 2008
    ..In conclusion the results support the folklore that a hot tasty drink is a beneficial treatment for relief of most symptoms of common cold and flu...
  41. doi request reprint The use of race as a demographic variable in clinical research
    S C Leong
    Common Cold Centre and Healthcare Clinical Trials, Cardiff School of Biosciences, Cardiff University, United Kingdom
    Rhinology 48:3-6. 2010
    ..Researchers continue to categorise demograpic variables according to racial lines despite the fact that the definition of race has no scientific or anthropological validity...
  42. pmc Coughing and choking in motor neuron disease
    S Hadjikoutis
    Department of Medicine Neurology, University of Wales College of Medicine, Cardiff, UK
    J Neurol Neurosurg Psychiatry 68:601-4. 2000
    ..To assess the frequency and severity of coughing and choking episodes, possible related factors, and their association with chest infections in patients with motor neuron disease (MND)...
  43. doi request reprint The role of anthropometric measurements in nasal surgery and research: a systematic review
    N M Doddi
    Common Cold Centre, Cardiff University, Cardiff, UK
    Clin Otolaryngol 35:277-83. 2010
    ..Data of average nasal anthropometric values for various ethnic groups is promoted to be of great importance in planning aesthetic nasal surgery, but there may be fundamental problems with this approach...
  44. doi request reprint A systematic review of the nasal index and the significance of the shape and size of the nose in rhinology
    S C Leong
    Common Cold Centre and Healthcare Clinical Trials, Cardiff School of Biosciences, Cardiff University, Cardiff, UK
    Clin Otolaryngol 34:191-8. 2009
    ..There was great interest in the 19th and early 20th century in classifying human races as Caucasian, Asian African etc. according to nasal shape and size, and the nasal index was the most commonly used measurement to differentiate races...
  45. ncbi request reprint Use of a portable spirometer for studies on the nasal cycle
    J Hanif
    Common Cold Center, University of Cardiff, Cardiff School of Biosciences, United Kingdom
    Am J Rhinol 15:303-6. 2001
    ..Spirometry has considerable advantages over rhinomanometry for studies on the nasal cycle because of portability and ease of use...
  46. ncbi request reprint Voluntary control of cough
    P C L Lee
    Common Cold Centre, Cardiff School of Biosciences, Cardiff, CF10 3US, UK
    Pulm Pharmacol Ther 15:317-20. 2002
    ..A cough model demonstrating the voluntary and reflex control of cough in man is proposed. A hypothesis is proposed that cough associated with common cold is a mixture of both reflex and voluntary cough...
  47. pmc Safety and Efficacy Profile of Echinacea purpurea to Prevent Common Cold Episodes: A Randomized, Double-Blind, Placebo-Controlled Trial
    M Jawad
    Common Cold Centre and Healthcare, Cardiff University, Cardiff CF10 3XQ, UK
    Evid Based Complement Alternat Med 2012:841315. 2012
    ..Conclusions. Compliant prophylactic intake of E. purpurea over a 4-month period appeared to provide a positive risk to benefit ratio...
  48. ncbi request reprint Paradoxical increase in nasal airway resistance following a topical nasal decongestant spray
    N M Doddi
    Common Cold Centre, Cardiff University, Cardiff, CF10 3AX, United Kingdom
    Rhinology 49:127. 2011
    ..Nasal obstruction is a very common problem associated with common cold and topical nasal decongestant sprays are effective symptomatic treatments causing a decrease in nasal airway resistance (NAR)...
  49. ncbi request reprint Understanding submucosal electrosurgery for the treatment of nasal turbinate enlargement
    S E J Farmer
    Common Cold Centre, Cardiff School of Biosciences, Cardiff University, UK
    J Laryngol Otol 121:615-22. 2007
    ....
  50. ncbi request reprint What, if any, is the value of septal surgery?
    D G Roblin
    Common Cold Centre, Cardiff School of Biosciences, Cardiff University, Cardiff, UK
    Clin Otolaryngol Allied Sci 27:77-80. 2002
  51. ncbi request reprint Efficacy and safety of single and multiple doses of pseudoephedrine in the treatment of nasal congestion associated with common cold
    Ronald Eccles
    Common Cold Centre, Cardiff School of Biosciences, Cardiff University, United Kingdom
    Am J Rhinol 19:25-31. 2005
    ..The present study has the aims of studying the safety and efficacy of a new pseudoephedrine formulation after single and multiple doses in patients with URTI...
  52. ncbi request reprint Efficacy and safety of topical combinations of ipratropium and xylometazoline for the treatment of symptoms of runny nose and nasal congestion associated with acute upper respiratory tract infection
    Ronald Eccles
    Common Cold Centre, Cardiff School of Biosciences, Cardiff University, United Kingdom
    Am J Rhinol 21:40-5. 2007
    ..This study investigated the efficacy and safety of a combination nasal spray of ipratropium and xylometazoline for simultaneous treatment of these symptoms...
  53. ncbi request reprint Paradoxical sensation of nasal airflow in patients with common cold. Are we measuring the correct modality?
    Jonathan D Clarke
    Common Cold Centre, Cardiff School of Biosciences, Cardiff University, Cardiff, UK
    Acta Otolaryngol 125:1307-11. 2005
    ..Improved methods for measuring nasal sensations are required to further investigate the relationship between objective and subjective measures of nasal obstruction...
  54. ncbi request reprint Acute cooling of the feet and the onset of common cold symptoms
    Claire Johnson
    Common Cold Centre, Cardiff School of Biosciences, Cardiff University, Cardiff CF10 3US, UK
    Fam Pract 22:608-13. 2005
    ....
  55. pmc "Drink plenty of fluids": no harm in fluids for colds and flu
    Ronald Eccles
    BMJ 328:957-8; author reply 958. 2004
  56. ncbi request reprint Normal range for nasal partitioning of airflow determined by nasal spirometry in 100 healthy subjects
    D Graham Roblin
    Common Cold Center Cardiff School of Biosciences, Cardiff University, Cardiff CF10 3US, United Kingdom
    Am J Rhinol 17:179-83. 2003
    ..This study investigated the normal range of NPR in the decongested nose as a means of assessing the degree of nasal septal deviation...
  57. ncbi request reprint Re: effects of unilateral naris closure on the nasal and maxillary sinus mucosa in rabbit by Seung-Heon Shin and Won-Wook Heo, Auris Nasus Larynx 32 (2005) 139-143
    Ronald Eccles
    Auris Nasus Larynx 33:117; author reply 119. 2006
  58. ncbi request reprint How good are patients at determining which side of the nose is more obstructed? A study on the limits of discrimination of the subjective assessment of unilateral nasal obstruction
    Jonathan D Clarke
    Common Cold Center, Cardiff School of Biosciences, Cardiff University, Cardiff, United Kingdom
    Am J Rhinol 20:20-4. 2006
    ..The aim of this study was to measure the minimum difference in unilateral airflow that can be reliably detected by a patient...