Eilis Dowd

Summary

Affiliation: Cardiff University
Country: UK

Publications

  1. ncbi request reprint Deficits in a lateralized associative learning task in dopamine-depleted rats with functional recovery by dopamine-rich transplants
    Eilis Dowd
    Brain Repair Group, School of Biosciences, Cardiff University, Wales, UK
    Eur J Neurosci 20:1953-9. 2004
  2. ncbi request reprint Comparison of 6-hydroxydopamine-induced medial forebrain bundle and nigrostriatal terminal lesions in a lateralised nose-poking task in rats
    Eilis Dowd
    Brain Repair Group, School of Biosciences, Cardiff University, Wales, Cardiff CF10 3US, UK
    Behav Brain Res 159:153-61. 2005
  3. ncbi request reprint Comparison of 6-hydroxydopamine-induced medial forebrain bundle and nigrostriatal terminal lesions in rats using a lateralised nose-poking task with low stimulus-response compatibility
    Eilis Dowd
    Brain Repair Group, School of Biosciences, Cardiff University, Cardiff CF10 3US, UK
    Behav Brain Res 165:181-6. 2005
  4. ncbi request reprint Lentivector-mediated delivery of GDNF protects complex motor functions relevant to human Parkinsonism in a rat lesion model
    Eilis Dowd
    Brain Repair Group, School of Biosciences, Cardiff University, Wales, UK
    Eur J Neurosci 22:2587-95. 2005
  5. ncbi request reprint The Corridor Task: a simple test of lateralised response selection sensitive to unilateral dopamine deafferentation and graft-derived dopamine replacement in the striatum
    Eilis Dowd
    Brain Repair Group, School of Biosciences, Cardiff University, Cardiff, CF10 3US Wales, UK
    Brain Res Bull 68:24-30. 2005
  6. doi request reprint Nigral grafts in animal models of Parkinson's disease. Is recovery beyond motor function possible?
    Mariah J Lelos
    Brain Repair Group, School of Biosciences, Cardiff University, Cardiff, Wales, UK
    Prog Brain Res 200:113-42. 2012

Detail Information

Publications6

  1. ncbi request reprint Deficits in a lateralized associative learning task in dopamine-depleted rats with functional recovery by dopamine-rich transplants
    Eilis Dowd
    Brain Repair Group, School of Biosciences, Cardiff University, Wales, UK
    Eur J Neurosci 20:1953-9. 2004
    ..This data suggests that this operant task may be a powerful tool for validating and elucidating the mechanism of action of experimental brain repair therapies prior to entering the clinic...
  2. ncbi request reprint Comparison of 6-hydroxydopamine-induced medial forebrain bundle and nigrostriatal terminal lesions in a lateralised nose-poking task in rats
    Eilis Dowd
    Brain Repair Group, School of Biosciences, Cardiff University, Wales, Cardiff CF10 3US, UK
    Behav Brain Res 159:153-61. 2005
    ..This experiment confirms that the lateralised nose-poking task may be a powerful tool for assessment of the nature of deficit and recovery in rats with complete but not partial unilateral dopamine lesions...
  3. ncbi request reprint Comparison of 6-hydroxydopamine-induced medial forebrain bundle and nigrostriatal terminal lesions in rats using a lateralised nose-poking task with low stimulus-response compatibility
    Eilis Dowd
    Brain Repair Group, School of Biosciences, Cardiff University, Cardiff CF10 3US, UK
    Behav Brain Res 165:181-6. 2005
    ....
  4. ncbi request reprint Lentivector-mediated delivery of GDNF protects complex motor functions relevant to human Parkinsonism in a rat lesion model
    Eilis Dowd
    Brain Repair Group, School of Biosciences, Cardiff University, Wales, UK
    Eur J Neurosci 22:2587-95. 2005
    ..This study confirms that GDNF can protect against 6-OHDA-induced impairments in complex as well as simple behaviours, and reinforces the use of EIAV-based vectors for the treatment of PD...
  5. ncbi request reprint The Corridor Task: a simple test of lateralised response selection sensitive to unilateral dopamine deafferentation and graft-derived dopamine replacement in the striatum
    Eilis Dowd
    Brain Repair Group, School of Biosciences, Cardiff University, Cardiff, CF10 3US Wales, UK
    Brain Res Bull 68:24-30. 2005
    ..We conclude that the Corridor Task is a sensitive test of lateralised sensorimotor response selection, and is suitable for assessing deficits and recovery associated with lesions and grafts within the nigrostriatal system...
  6. doi request reprint Nigral grafts in animal models of Parkinson's disease. Is recovery beyond motor function possible?
    Mariah J Lelos
    Brain Repair Group, School of Biosciences, Cardiff University, Cardiff, Wales, UK
    Prog Brain Res 200:113-42. 2012
    ..We can now consider the prospect of rewriting the opportunities for treating patients, with new stem cell sources to be complemented by new targets for therapeutic benefit...