William Davies

Summary

Affiliation: Cardiff University
Country: UK

Publications

  1. pmc Converging pharmacological and genetic evidence indicates a role for steroid sulfatase in attention
    William Davies
    Behavioural Genetics Group, School of Psychology and Department of Psychological Medicine, School of Medicine, University of Cardiff, London, United Kingdom
    Biol Psychiatry 66:360-7. 2009
  2. doi request reprint Genomic imprinting on the X chromosome: implications for brain and behavioral phenotypes
    William Davies
    MRC Centre for Neuropsychiatric Genetics and Genomics, Department of Psychological Medicine and Neurology, Schools of Medicine and Psychology, Cardiff University, Cardiff, United Kingdom
    Ann N Y Acad Sci 1204:E14-9. 2010
  3. doi request reprint Does steroid sulfatase deficiency influence postpartum psychosis risk?
    William Davies
    Behavioural Genetics Group, Schools of Medicine and Psychology, Cardiff University, Cardiff, UK
    Trends Mol Med 18:256-62. 2012
  4. ncbi request reprint Sex differences in attention Deficit Hyperactivity Disorder: candidate genetic and endocrine mechanisms
    William Davies
    Behavioural Genetics Group, Neuroscience and Mental Health Research Institute, Schools of Psychology and Medicine, Cardiff University, Tower Building, Park Place, Cardiff CF10 3AT, UK Medical Research Council Centre for Neuropsychiatric Genetics and Genomics, Cardiff University, Hadyn Ellis Building, Cardiff CF24 4HQ, UK Electronic address
    Front Neuroendocrinol 35:331-46. 2014
  5. pmc Steroid sulfatase-deficient mice exhibit endophenotypes relevant to attention deficit hyperactivity disorder
    Simon Trent
    Behavioural Genetics Group, Schools of Psychology and Medicine, Cardiff University, Cardiff, UK
    Psychoneuroendocrinology 37:221-9. 2012
  6. pmc Biological mechanisms associated with increased perseveration and hyperactivity in a genetic mouse model of neurodevelopmental disorder
    Simon Trent
    Behavioural Genetics Group and Neuroscience and Mental Health Research Institute, Schools of Psychology and Medicine, Cardiff University, Cardiff, UK
    Psychoneuroendocrinology 38:1370-80. 2013
  7. pmc Dissociable effects of Sry and sex chromosome complement on activity, feeding and anxiety-related behaviours in mice
    Eleni Kopsida
    Neuroscience and Mental Health Research Institute, Cardiff University, Cardiff, South Glamorgan, United Kingdom
    PLoS ONE 8:e73699. 2013
  8. pmc Functional themes from psychiatric genome-wide screens
    William Davies
    Behavioural Genetics Group, Schools of Medicine and Psychology, Cardiff University Cardiff, UK
    Front Genet 2:89. 2011
  9. pmc Steroid sulfatase is a potential modifier of cognition in attention deficit hyperactivity disorder
    E Stergiakouli
    MRC Centre for Neuropsychiatric Genetics and Genomics and Department of Psychological Medicine and Neurology, School of Medicine, Cardiff University, Cardiff, UK
    Genes Brain Behav 10:334-44. 2011
  10. doi request reprint Using mouse models to investigate sex-linked genetic effects on brain, behaviour and vulnerability to neuropsychiatric disorders
    William Davies
    Behavioural Genetics Group, MRC Centre for Neuropsychiatric Genetics and Genomics, Neuroscience and Mental Health Research Institute, Schools of Medicine and Psychology, Cardiff University, United Kingdom
    Brain Res Bull 92:12-20. 2013

Collaborators

Detail Information

Publications24

  1. pmc Converging pharmacological and genetic evidence indicates a role for steroid sulfatase in attention
    William Davies
    Behavioural Genetics Group, School of Psychology and Department of Psychological Medicine, School of Medicine, University of Cardiff, London, United Kingdom
    Biol Psychiatry 66:360-7. 2009
    ..Preliminary work in mice and humans has suggested the X-linked gene STS (which encodes the enzyme steroid sulfatase) as a mediator of attentional functioning and as a candidate gene for ADHD...
  2. doi request reprint Genomic imprinting on the X chromosome: implications for brain and behavioral phenotypes
    William Davies
    MRC Centre for Neuropsychiatric Genetics and Genomics, Department of Psychological Medicine and Neurology, Schools of Medicine and Psychology, Cardiff University, Cardiff, United Kingdom
    Ann N Y Acad Sci 1204:E14-9. 2010
    ....
  3. doi request reprint Does steroid sulfatase deficiency influence postpartum psychosis risk?
    William Davies
    Behavioural Genetics Group, Schools of Medicine and Psychology, Cardiff University, Cardiff, UK
    Trends Mol Med 18:256-62. 2012
    ....
  4. ncbi request reprint Sex differences in attention Deficit Hyperactivity Disorder: candidate genetic and endocrine mechanisms
    William Davies
    Behavioural Genetics Group, Neuroscience and Mental Health Research Institute, Schools of Psychology and Medicine, Cardiff University, Tower Building, Park Place, Cardiff CF10 3AT, UK Medical Research Council Centre for Neuropsychiatric Genetics and Genomics, Cardiff University, Hadyn Ellis Building, Cardiff CF24 4HQ, UK Electronic address
    Front Neuroendocrinol 35:331-46. 2014
    ....
  5. pmc Steroid sulfatase-deficient mice exhibit endophenotypes relevant to attention deficit hyperactivity disorder
    Simon Trent
    Behavioural Genetics Group, Schools of Psychology and Medicine, Cardiff University, Cardiff, UK
    Psychoneuroendocrinology 37:221-9. 2012
    ....
  6. pmc Biological mechanisms associated with increased perseveration and hyperactivity in a genetic mouse model of neurodevelopmental disorder
    Simon Trent
    Behavioural Genetics Group and Neuroscience and Mental Health Research Institute, Schools of Psychology and Medicine, Cardiff University, Cardiff, UK
    Psychoneuroendocrinology 38:1370-80. 2013
    ....
  7. pmc Dissociable effects of Sry and sex chromosome complement on activity, feeding and anxiety-related behaviours in mice
    Eleni Kopsida
    Neuroscience and Mental Health Research Institute, Cardiff University, Cardiff, South Glamorgan, United Kingdom
    PLoS ONE 8:e73699. 2013
    ..Our results may have relevance for understanding the molecular underpinnings of sexually dimorphic behavioural phenotypes in healthy men and women, and in individuals with abnormal sex chromosome constitutions. ..
  8. pmc Functional themes from psychiatric genome-wide screens
    William Davies
    Behavioural Genetics Group, Schools of Medicine and Psychology, Cardiff University Cardiff, UK
    Front Genet 2:89. 2011
    ..The power of focused cross-species studies needs to be effectively exploited to enable useful insights into the molecular pathogenesis of common and disabling disorders, and ultimately to provide better clinical outcomes for patients...
  9. pmc Steroid sulfatase is a potential modifier of cognition in attention deficit hyperactivity disorder
    E Stergiakouli
    MRC Centre for Neuropsychiatric Genetics and Genomics and Department of Psychological Medicine and Neurology, School of Medicine, Cardiff University, Cardiff, UK
    Genes Brain Behav 10:334-44. 2011
    ..These data suggest that genetic variants affecting STS expression and/or activity could influence the function of brain regions perturbed in ADHD...
  10. doi request reprint Using mouse models to investigate sex-linked genetic effects on brain, behaviour and vulnerability to neuropsychiatric disorders
    William Davies
    Behavioural Genetics Group, MRC Centre for Neuropsychiatric Genetics and Genomics, Neuroscience and Mental Health Research Institute, Schools of Medicine and Psychology, Cardiff University, United Kingdom
    Brain Res Bull 92:12-20. 2013
    ....
  11. ncbi request reprint What are imprinted genes doing in the brain?
    William Davies
    Department of Psychological Medicine, University of Cardiff, Henry Wellcome Building, Heath Park, Cardiff, Wales, UK
    Adv Exp Med Biol 626:62-70. 2008
    ....
  12. doi request reprint Imprinted genes and neuroendocrine function
    William Davies
    Behavioural Genetics Group, Department of Psychological Medicine and School of Psychology, School of Medicine, University of Cardiff, Cardiff, UK
    Front Neuroendocrinol 29:413-27. 2008
    ....
  13. ncbi request reprint What are imprinted genes doing in the brain?
    William Davies
    Behavioral Genetics Group, Department of Psychological Medicine and School of Psychology, School of Medicine, University of Cardiff, Cardiff, Wales, UK
    Epigenetics 2:201-6. 2007
    ....
  14. pmc Altered serotonergic function may partially account for behavioral endophenotypes in steroid sulfatase-deficient mice
    Simon Trent
    Behavioral Genetics Group, Schools of Medicine and Psychology, Cardiff University, Cardiff, UK
    Neuropsychopharmacology 37:1267-74. 2012
    ..These data suggest that inactivating mutations and functional variants within STS might exert their influence on ADHD vulnerability, and disorder endophenotypes through modulation of the serotonergic system...
  15. pmc The influence of sex-linked genetic mechanisms on attention and impulsivity
    Simon Trent
    Behavioural Genetics Group, MRC Centre for Neuropsychiatric Genetics and Genomics, Neuroscience and Mental Health Research Institute, Schools of Psychology and Medicine, Cardiff University, United Kingdom
    Biol Psychol 89:1-13. 2012
    ..Identifying novel sex-modulated molecular targets should ultimately enable us to develop more effective therapies in disorders associated with attentional/impulsive dysfunction...
  16. pmc Genomic imprinting and the social brain
    Anthony R Isles
    Laboratory of Cognitive and Behavioural Neuroscience, The Babraham Institute, Babraham Research Campus, Babraham, Cambridge CB2 4AT, UK
    Philos Trans R Soc Lond B Biol Sci 361:2229-37. 2006
    ....
  17. doi request reprint The role of imprinted genes in mediating susceptibility to neuropsychiatric disorders
    Eleni Kopsida
    Behavioral Genetics Group, Cardiff University, UK
    Horm Behav 59:375-82. 2011
    ....
  18. ncbi request reprint The 39,XO mouse as a model for the neurobiology of Turner syndrome and sex-biased neuropsychiatric disorders
    Phoebe M Y Lynn
    Behavioural Genetics Group, School of Psychology and Department of Psychological Medicine, University of Cardiff, UK
    Behav Brain Res 179:173-82. 2007
    ....
  19. ncbi request reprint Genomic imprinting effects on brain development and function
    Lawrence S Wilkinson
    Behavioural Genetics Group, School of Psychology and Department of Psychological Medicine, School of Medicine, Cardiff University, Tower Building, Park Place, Cardiff, CF10 3AT, UK
    Nat Rev Neurosci 8:832-43. 2007
    ..There is increasing evidence that imprinted genes influence brain function and behaviour by affecting neurodevelopmental processes...
  20. ncbi request reprint It is not all hormones: alternative explanations for sexual differentiation of the brain
    William Davies
    The Babraham Institute, Babraham Research Campus, Babraham, Cambridge CB2 4AT, UK
    Brain Res 1126:36-45. 2006
    ..Ultimately, it is hoped that such studies will provide insights into why men and women are differentially vulnerable to certain mental disorders, and will enable the development of effective sex-tailored therapeutics...
  21. ncbi request reprint X-linked imprinting: effects on brain and behaviour
    William Davies
    Laboratories of Cognitive and Behavioural Neuroscience and Developmental Genetics and Imprinting, The Babraham Institute, Cambridge, UK
    Bioessays 28:35-44. 2006
    ..In addition, we suggest strategies for identifying novel X-linked imprinted genes and their downstream effects and discuss evolutionary theories regarding the origin and maintenance of X-linked imprinting...
  22. ncbi request reprint Xlr3b is a new imprinted candidate for X-linked parent-of-origin effects on cognitive function in mice
    William Davies
    Laboratories of Cognitive and Behavioral Neuroscience and Developmental Genetics and Imprinting, The Babraham Institute, The Babraham Research Campus, Cambridge, CB2 4AT, UK
    Nat Genet 37:625-9. 2005
    ....
  23. ncbi request reprint Imprinted gene expression in the brain
    William Davies
    Neurobiology and Developmental Genetics Programmes, The Babraham Institute, Babraham, Cambridge CB2 4AT, UK
    Neurosci Biobehav Rev 29:421-30. 2005
    ....
  24. ncbi request reprint Expression patterns of the novel imprinted genes Nap1l5 and Peg13 and their non-imprinted host genes in the adult mouse brain
    William Davies
    Developmental Genetics and Neurobiology Programmes, The Babraham Institute, Babraham, Cambridge CB2 4AT, UK
    Gene Expr Patterns 4:741-7. 2004
    ..Nap1l5 expression was localised mainly to the adrenal medulla, whilst Peg13 expression was observed more generally throughout the adrenal medulla and the outer cortical layers...