Research Topics
Species | William DaviesSummaryAffiliation: Cardiff University Country: UK Publications
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Publications
Converging pharmacological and genetic evidence indicates a role for steroid sulfatase in attentionWilliam Davies
Behavioural Genetics Group, School of Psychology and Department of Psychological Medicine, School of Medicine, University of Cardiff, London, United Kingdom
Biol Psychiatry 66:360-7. 2009..Preliminary work in mice and humans has suggested the X-linked gene STS (which encodes the enzyme steroid sulfatase) as a mediator of attentional functioning and as a candidate gene for ADHD...
Genomic imprinting on the X chromosome: implications for brain and behavioral phenotypesWilliam Davies
MRC Centre for Neuropsychiatric Genetics and Genomics, Department of Psychological Medicine and Neurology, Schools of Medicine and Psychology, Cardiff University, Cardiff, United Kingdom
Ann N Y Acad Sci 1204:E14-9. 2010....
Does steroid sulfatase deficiency influence postpartum psychosis risk?William Davies
Behavioural Genetics Group, Schools of Medicine and Psychology, Cardiff University, Cardiff, UK
Trends Mol Med 18:256-62. 2012....
Using mouse models to investigate sex-linked genetic effects on brain, behaviour and vulnerability to neuropsychiatric disordersWilliam Davies
Behavioural Genetics Group, MRC Centre for Neuropsychiatric Genetics and Genomics, Neuroscience and Mental Health Research Institute, Schools of Medicine and Psychology, Cardiff University, United Kingdom
Brain Res Bull 92:12-20. 2013....
What are imprinted genes doing in the brain?William Davies
Department of Psychological Medicine, University of Cardiff, Henry Wellcome Building, Heath Park, Cardiff, Wales, UK
Adv Exp Med Biol 626:62-70. 2008....
Imprinted genes and neuroendocrine functionWilliam Davies
Behavioural Genetics Group, Department of Psychological Medicine and School of Psychology, School of Medicine, University of Cardiff, Cardiff, UK
Front Neuroendocrinol 29:413-27. 2008....
What are imprinted genes doing in the brain?William Davies
Behavioral Genetics Group, Department of Psychological Medicine and School of Psychology, School of Medicine, University of Cardiff, Cardiff, Wales, UK
Epigenetics 2:201-6. 2007....
Steroid sulfatase-deficient mice exhibit endophenotypes relevant to attention deficit hyperactivity disorderSimon Trent
Behavioural Genetics Group, Schools of Psychology and Medicine, Cardiff University, Cardiff, UK
Psychoneuroendocrinology 37:221-9. 2012....
Altered serotonergic function may partially account for behavioral endophenotypes in steroid sulfatase-deficient miceSimon Trent
Behavioral Genetics Group, Schools of Medicine and Psychology, Cardiff University, Cardiff, UK
Neuropsychopharmacology 37:1267-74. 2012..These data suggest that inactivating mutations and functional variants within STS might exert their influence on ADHD vulnerability, and disorder endophenotypes through modulation of the serotonergic system...
Genomic imprinting and the social brainAnthony R Isles
Laboratory of Cognitive and Behavioural Neuroscience, The Babraham Institute, Babraham Research Campus, Babraham, Cambridge CB2 4AT, UK
Philos Trans R Soc Lond B Biol Sci 361:2229-37. 2006....
The influence of sex-linked genetic mechanisms on attention and impulsivitySimon Trent
Behavioural Genetics Group, MRC Centre for Neuropsychiatric Genetics and Genomics, Neuroscience and Mental Health Research Institute, Schools of Psychology and Medicine, Cardiff University, United Kingdom
Biol Psychol 89:1-13. 2012..Identifying novel sex-modulated molecular targets should ultimately enable us to develop more effective therapies in disorders associated with attentional/impulsive dysfunction...
Genomic imprinting effects on brain development and functionLawrence S Wilkinson
Behavioural Genetics Group, School of Psychology and Department of Psychological Medicine, School of Medicine, Cardiff University, Tower Building, Park Place, Cardiff, CF10 3AT, UK
Nat Rev Neurosci 8:832-43. 2007..There is increasing evidence that imprinted genes influence brain function and behaviour by affecting neurodevelopmental processes...
The 39,XO mouse as a model for the neurobiology of Turner syndrome and sex-biased neuropsychiatric disordersPhoebe M Y Lynn
Behavioural Genetics Group, School of Psychology and Department of Psychological Medicine, University of Cardiff, UK
Behav Brain Res 179:173-82. 2007....
The role of imprinted genes in mediating susceptibility to neuropsychiatric disordersEleni Kopsida
Behavioral Genetics Group, Cardiff University, UK
Horm Behav 59:375-82. 2011....
Imprinted gene expression in the brainWilliam Davies
Neurobiology and Developmental Genetics Programmes, The Babraham Institute, Babraham, Cambridge CB2 4AT, UK
Neurosci Biobehav Rev 29:421-30. 2005....
Xlr3b is a new imprinted candidate for X-linked parent-of-origin effects on cognitive function in miceWilliam Davies
Laboratories of Cognitive and Behavioral Neuroscience and Developmental Genetics and Imprinting, The Babraham Institute, The Babraham Research Campus, Cambridge, CB2 4AT, UK
Nat Genet 37:625-9. 2005....
X-linked imprinting: effects on brain and behaviourWilliam Davies
Laboratories of Cognitive and Behavioural Neuroscience and Developmental Genetics and Imprinting, The Babraham Institute, Cambridge, UK
Bioessays 28:35-44. 2006..In addition, we suggest strategies for identifying novel X-linked imprinted genes and their downstream effects and discuss evolutionary theories regarding the origin and maintenance of X-linked imprinting...
It is not all hormones: alternative explanations for sexual differentiation of the brainWilliam Davies
The Babraham Institute, Babraham Research Campus, Babraham, Cambridge CB2 4AT, UK
Brain Res 1126:36-45. 2006..Ultimately, it is hoped that such studies will provide insights into why men and women are differentially vulnerable to certain mental disorders, and will enable the development of effective sex-tailored therapeutics...
Expression patterns of the novel imprinted genes Nap1l5 and Peg13 and their non-imprinted host genes in the adult mouse brainWilliam Davies
Developmental Genetics and Neurobiology Programmes, The Babraham Institute, Babraham, Cambridge CB2 4AT, UK
Gene Expr Patterns 4:741-7. 2004..Nap1l5 expression was localised mainly to the adrenal medulla, whilst Peg13 expression was observed more generally throughout the adrenal medulla and the outer cortical layers...
