Craig Boote

Summary

Affiliation: Cardiff University
Country: UK

Publications

  1. pmc Quantitative assessment of ultrastructure and light scatter in mouse corneal debridement wounds
    Craig Boote
    Structural Biophysics Group, School of Optometry and Vision Sciences, Cardiff University, Cardiff, United Kingdom
    Invest Ophthalmol Vis Sci 53:2786-95. 2012
  2. pmc The influence of lamellar orientation on corneal material behavior: biomechanical and structural changes in an avian corneal disorder
    Craig Boote
    Structural Biophysics Group, School of Optometry and Vision Sciences, Cardiff University, Cardiff, United Kingdom
    Invest Ophthalmol Vis Sci 52:1243-51. 2011
  3. ncbi request reprint Collagen fibrils appear more closely packed in the prepupillary cornea: optical and biomechanical implications
    Craig Boote
    Department of Optometry and Vision Sciences, Cardiff University, Cardiff, Wales, United Kingdom
    Invest Ophthalmol Vis Sci 44:2941-8. 2003
  4. pmc Ultrastructural changes in the retinopathy, globe enlarged (rge) chick cornea
    Craig Boote
    Structural Biophysics Group, School of Optometry and Vision Sciences, Cardiff University, Maindy Road, Cardiff CF24 4LU, UK
    J Struct Biol 166:195-204. 2009
  5. ncbi request reprint Spatial mapping of collagen fibril organisation in primate cornea-an X-ray diffraction investigation
    Craig Boote
    Structural Biophysics Group, School of Optometry and Vision Sciences, Cardiff University, Wales, UK
    J Struct Biol 146:359-67. 2004
  6. ncbi request reprint Lamellar orientation in human cornea in relation to mechanical properties
    Craig Boote
    Structural Biophysics Group, School of Optometry and Vision Sciences, Cardiff University, Wales, UK
    J Struct Biol 149:1-6. 2005
  7. pmc The effect of riboflavin/UVA collagen cross-linking therapy on the structure and hydrodynamic behaviour of the ungulate and rabbit corneal stroma
    Sally Hayes
    Structural Biophysics Research Group, School of Optometry and Vision Sciences, Cardiff University, Cardiff, United Kingdom
    PLoS ONE 8:e52860. 2013
  8. ncbi request reprint Collagen organization in the chicken cornea and structural alterations in the retinopathy, globe enlarged (rge) phenotype--an X-ray diffraction study
    Craig Boote
    Structural Biophysics Group, School of Optometry and Vision Sciences, Cardiff University, Maindy Road, Cardiff CF24 4LU, UK
    J Struct Biol 161:1-8. 2008
  9. pmc Quantification of collagen organization in the peripheral human cornea at micron-scale resolution
    Craig Boote
    Structural Biophysics Group, School of Optometry and Vision Sciences, Cardiff University, Cardiff, United Kingdom
    Biophys J 101:33-42. 2011
  10. doi request reprint Collagen and mature elastic fibre organisation as a function of depth in the human cornea and limbus
    Christina S Kamma-Lorger
    Structural Biophysics Research Group, School of Optometry and Vision Sciences, Maindy Road, Cardiff University, Cardiff CF24 4LU, UK
    J Struct Biol 169:424-30. 2010

Collaborators

Detail Information

Publications28

  1. pmc Quantitative assessment of ultrastructure and light scatter in mouse corneal debridement wounds
    Craig Boote
    Structural Biophysics Group, School of Optometry and Vision Sciences, Cardiff University, Cardiff, United Kingdom
    Invest Ophthalmol Vis Sci 53:2786-95. 2012
    ..The aim of the current study was to quantify changes in stromal ultrastructure and light scatter that characterize fibrosis in mouse corneal debridement wounds...
  2. pmc The influence of lamellar orientation on corneal material behavior: biomechanical and structural changes in an avian corneal disorder
    Craig Boote
    Structural Biophysics Group, School of Optometry and Vision Sciences, Cardiff University, Cardiff, United Kingdom
    Invest Ophthalmol Vis Sci 52:1243-51. 2011
    ....
  3. ncbi request reprint Collagen fibrils appear more closely packed in the prepupillary cornea: optical and biomechanical implications
    Craig Boote
    Department of Optometry and Vision Sciences, Cardiff University, Cardiff, Wales, United Kingdom
    Invest Ophthalmol Vis Sci 44:2941-8. 2003
    ..The present study was designed to quantify the collagen fibril spacing and diameter across the normal human cornea and to relate this to the properties of the tissue...
  4. pmc Ultrastructural changes in the retinopathy, globe enlarged (rge) chick cornea
    Craig Boote
    Structural Biophysics Group, School of Optometry and Vision Sciences, Cardiff University, Maindy Road, Cardiff CF24 4LU, UK
    J Struct Biol 166:195-204. 2009
    ..From a numerical simulation of tissue mechanics, progressive remodelling of stromal collagen in rge during globe enlargement post-hatch appears to be related to the corneal morphometric changes presented by the disease...
  5. ncbi request reprint Spatial mapping of collagen fibril organisation in primate cornea-an X-ray diffraction investigation
    Craig Boote
    Structural Biophysics Group, School of Optometry and Vision Sciences, Cardiff University, Wales, UK
    J Struct Biol 146:359-67. 2004
    ..Implications for the mechanical and optical properties of the cornea are discussed...
  6. ncbi request reprint Lamellar orientation in human cornea in relation to mechanical properties
    Craig Boote
    Structural Biophysics Group, School of Optometry and Vision Sciences, Cardiff University, Wales, UK
    J Struct Biol 149:1-6. 2005
    ..It is possible that, through a direct impact on the elastic modulus of the tissue, an imbalance of superior-inferior and nasal-temporal fibrils in some eyes might affect corneal shape...
  7. pmc The effect of riboflavin/UVA collagen cross-linking therapy on the structure and hydrodynamic behaviour of the ungulate and rabbit corneal stroma
    Sally Hayes
    Structural Biophysics Research Group, School of Optometry and Vision Sciences, Cardiff University, Cardiff, United Kingdom
    PLoS ONE 8:e52860. 2013
    ..To examine the effect of riboflavin/UVA corneal crosslinking on stromal ultrastructure and hydrodynamic behaviour...
  8. ncbi request reprint Collagen organization in the chicken cornea and structural alterations in the retinopathy, globe enlarged (rge) phenotype--an X-ray diffraction study
    Craig Boote
    Structural Biophysics Group, School of Optometry and Vision Sciences, Cardiff University, Maindy Road, Cardiff CF24 4LU, UK
    J Struct Biol 161:1-8. 2008
    ..We postulate that corneal flattening in rge chickens may be related to biomechanical changes brought about by an alteration in collagen arrangement at the corneal periphery...
  9. pmc Quantification of collagen organization in the peripheral human cornea at micron-scale resolution
    Craig Boote
    Structural Biophysics Group, School of Optometry and Vision Sciences, Cardiff University, Cardiff, United Kingdom
    Biophys J 101:33-42. 2011
    ..The results have implications for the cornea's biomechanical response to ocular surgeries involving peripheral incision...
  10. doi request reprint Collagen and mature elastic fibre organisation as a function of depth in the human cornea and limbus
    Christina S Kamma-Lorger
    Structural Biophysics Research Group, School of Optometry and Vision Sciences, Maindy Road, Cardiff University, Cardiff CF24 4LU, UK
    J Struct Biol 169:424-30. 2010
    ..This information will aid the development of corneal biomechanical models aimed at explaining how normal corneal curvature is sustained and further predicting the outcome of surgical procedures...
  11. pmc Effects on collagen orientation in the cornea after trephine injury
    Christina S Kamma-Lorger
    Structural Biophysics Group, School of Optometry and Vision Sciences, Cardiff University, Wales, UK
    Mol Vis 15:378-85. 2009
    ..Structural changes are well known to occur in the cornea after injury. The aim of this study was to investigate collagen orientation changes in the cornea during a short-term wound healing process...
  12. pmc Quantification of collagen ultrastructure after penetrating keratoplasty - implications for corneal biomechanics
    Craig Boote
    Structural Biophysics Group, School of Optometry and Vision Sciences, Cardiff University, Cardiff, United Kingdom
    PLoS ONE 8:e68166. 2013
    ..To quantify long-term changes in stromal collagen ultrastructure following penetrating keratoplasty (PK), and evaluate their possible implications for corneal biomechanics...
  13. pmc The effect of vitamin C deficiency and chronic ultraviolet-B exposure on corneal ultrastructure: a preliminary investigation
    Sally Hayes
    School of Optometry and Vision Sciences, Cardiff University, Cardiff, United Kingdom
    Mol Vis 17:3107-15. 2011
    ..This study examines the effect of dietary ascorbate levels and ultraviolet (UV)-B exposure on corneal stromal structure...
  14. ncbi request reprint Comparative study of fibrillar collagen arrangement in the corneas of primates and other mammals
    Sally Hayes
    Structural Biophysics Research Group, School of Optometry and Vision Institute, Cardiff University, Cardiff, United Kingdom
    Anat Rec (Hoboken) 290:1542-50. 2007
    ..This finding may be related to differences in the frequency of action and the forces generated by the various extraocular muscles during eye movement and image fixation...
  15. ncbi request reprint Annulus of collagen fibrils in mouse cornea and structural matrix alterations in a murine-specific keratopathy
    Andrew J Quantock
    Structural Biophysics Group, Department of Optometry and Vision Sciences, Cardiff University, Cardiff, Wales, United Kingdom
    Invest Ophthalmol Vis Sci 44:1906-11. 2003
    ..Mice with corneas predisposed to topographical changes (the SKC strain) were also examined, to establish the size and spacing of stromal collagen fibrils and the integrity of the annulus...
  16. doi request reprint Structural collagen alterations in macular corneal dystrophy occur mainly in the posterior stroma
    Barbara P Palka
    School of Optometry and Vision Sciences, Cardiff University, Cardiff, United Kingdom
    Curr Eye Res 35:580-6. 2010
    ..This study was conducted to investigate if this occurs uniformly across the stroma or is more prevalent at certain stromal depths...
  17. pmc An x-ray scattering study into the structural basis of corneal refractive function in an avian model
    Siân R Morgan
    Structural Biophysics Group, School of Optometry and Vision Sciences, Cardiff University, Cardiff, UK
    Biophys J 104:2586-94. 2013
    ....
  18. doi request reprint Collagen ultrastructural changes during stromal wound healing in organ cultured bovine corneas
    Christina S Kamma-Lorger
    Structural Biophysics Group, School of Optometry and Vision Sciences, Cardiff University, Wales, UK
    Exp Eye Res 88:953-9. 2009
    ..We conclude that stromal swelling is more rapid for trephine-wounded corneas than in stromal flaps, indicating that the intensity of the corneal healing response depends on the type of injury...
  19. pmc Riboflavin/UVA collagen cross-linking-induced changes in normal and keratoconus corneal stroma
    Sally Hayes
    Structural Biophysics Research Group, School of Optometry and Vision Sciences, Cardiff University, Cardiff, United Kingdom
    PLoS ONE 6:e22405. 2011
    ..To determine the effect of Ultraviolet-A collagen cross-linking with hypo-osmolar and iso-osmolar riboflavin solutions on stromal collagen ultrastructure in normal and keratoconus ex vivo human corneas...
  20. pmc Stromal edema in klf4 conditional null mouse cornea is associated with altered collagen fibril organization and reduced proteoglycans
    Robert D Young
    Structural Biophysics Group, School of Optometry and Vision Sciences, Cardiff University, Cardiff, Wales, United Kingdom
    Invest Ophthalmol Vis Sci 50:4155-61. 2009
    ..In this study, the structure and proteoglycan composition of the Klf4 conditional null (Klf4CN) corneal stroma was investigated, to further characterize the previously reported Klf4CN stromal edema...
  21. doi request reprint Changes in corneal collagen architecture during mouse postnatal development
    Jack Sheppard
    School of Optometry and Vision Sciences, Cardiff University, Cardiff, United Kingdom
    Invest Ophthalmol Vis Sci 51:2936-42. 2010
    ..To characterize changes in corneal collagen arrangement during mouse postnatal development...
  22. doi request reprint The use of X-ray scattering techniques to quantify the orientation and distribution of collagen in the corneal stroma
    Keith M Meek
    Structural Biophysics Group, School of Optometry and Vision Sciences, Cardiff University, Cardiff, UK
    Prog Retin Eye Res 28:369-92. 2009
    ..The implications of the knowledge gained so far are discussed in relation to the optical and biomechanical properties of the cornea, and their alteration due to disease and surgical intervention...
  23. ncbi request reprint A study of corneal thickness, shape and collagen organisation in keratoconus using videokeratography and X-ray scattering techniques
    Sally Hayes
    Structural Biophysics Research Group, School of Optometry and Vision Sciences, Cardiff University, Redwood Building, King Edward VII Avenue, Cardiff, CF10 3NB, United Kingdom
    Exp Eye Res 84:423-34. 2007
    ..The observed abnormalities in collagen distribution and orientation are consistent with a mechanism of keratoconus progression that involves inter-fibrillar or inter-lamellar slippage causing a redistribution of tissue within the cornea...
  24. ncbi request reprint Mapping collagen organization in the human cornea: left and right eyes are structurally distinct
    Craig Boote
    Structural Biophysics Group, School of Optometry and Vision Sciences, Cardiff University, Cardiff, Wales, United Kingdom
    Invest Ophthalmol Vis Sci 47:901-8. 2006
    ..The present study was designed to examine and compare the organization of collagen fibrils in the corneal stroma of left and right eyes...
  25. ncbi request reprint The organization of collagen in the corneal stroma
    Keith M Meek
    Structural Biophysics Group, Department of Optometry and Vision Sciences, Cardiff University, Redwood Building, King Edward VII Avenue, Cardiff CF10 3NB, UK
    Exp Eye Res 78:503-12. 2004
    ....
  26. pmc Quantitative mapping of collagen fiber orientation in non-glaucoma and glaucoma posterior human sclerae
    Jacek K Pijanka
    Structural Biophysics Group, School of Optometry and Vision Sciences, Cardiff University, Cardiff, United Kingdom
    Invest Ophthalmol Vis Sci 53:5258-70. 2012
    ..Scleral material properties are influenced significantly by collagen fiber architecture. Here we quantitatively map fiber orientation in non-glaucoma and glaucoma posterior human sclerae...
  27. ncbi request reprint An X-ray scattering investigation of corneal structure in keratocan-deficient mice
    Keith M Meek
    Structural Biophysics Group, Cardiff School of Optometry and Vision Sciences, Cardiff University, King Edward VII Avenue, Cardiff CF10 3NB, Wales, UK
    Matrix Biol 22:467-75. 2003
    ..Alternatively, it might change the osmotic balance between the inside and outside of fibrils, causing them to swell and move further apart...
  28. ncbi request reprint Collagen organization in the secondary chick cornea during development
    Andrew J Quantock
    Biophysics Group, Department of Optometry and Vision Sciences, Cardiff University, Redwood Building, King Edward VII Avenue, Cathays Park, Cardiff CF10 3NB, Wales, UK
    Invest Ophthalmol Vis Sci 44:130-6. 2003
    ..This study was designed to provide better appreciation of collagen reorganization in the avian corneal stroma during the latter stages of embryogenesis...