Derek J Blake
Affiliation: Cardiff University
Blake D, Forrest M, Chapman R, Tinsley C, O Donovan M, Owen M. TCF4, schizophrenia, and Pitt-Hopkins Syndrome. Schizophr Bull. 2010;36:443-7 pubmed publisher
..These data suggest that TCF4, NRXN1, and CNTNAP2 may participate in a biological pathway that is altered in patients with schizophrenia and other neuropsychiatric disorders. ..
Gyongyosi M, Haller P, Blake D, Martin Rendon E. Meta-Analysis of Cell Therapy Studies in Heart Failure and Acute Myocardial Infarction. Circ Res. 2018;123:301-308 pubmed publisher
Forrest M, Hill M, Quantock A, Martin Rendon E, Blake D. The emerging roles of TCF4 in disease and development. Trends Mol Med. 2014;20:322-31 pubmed publisher
..Here, we review the role of TCF4 in these seemingly diverse disorders and discuss recent data implicating TCF4 as an important regulator of neurodevelopment and epithelial-mesenchymal transition. ..
Peall K, Ritz K, Waite A, Groen J, Morris H, Baas F, et al
. SGCZ mutations are unlikely to be associated with myoclonus dystonia. Neuroscience. 2014;272:88-91 pubmed publisher
..No pathogenic SGCZ mutations were identified. SGCZ mutations are unlikely to contribute to the genetic heterogeneity in MDS. ..
Benson M, Tinsley C, Waite A, Carlisle F, Sweet S, Ehler E, et al
. Ryanodine receptors are part of the myospryn complex in cardiac muscle. Sci Rep. 2017;7:6312 pubmed publisher
..Together these data suggest a novel role for the myospryn complex in the assembly of ryanodine receptor clusters in striated muscle. ..