Noel C Wortham

Summary

Affiliation: Cancer Research UK
Country: UK

Publications

  1. ncbi Dercum's disease
    Noel C Wortham
    Molecular and Population Genetics Laboratory, Cancer Research UK, London, England
    Skinmed 4:157-62; quiz 163-4. 2005
  2. ncbi Aberrant expression of apoptosis proteins and ultrastructural aberrations in uterine leiomyomas from patients with hereditary leiomyomatosis and renal cell carcinoma
    Noel C Wortham
    Molecular and Population Genetics Laboratory, Cancer Research UK, London, United Kingdom
    Fertil Steril 86:961-71. 2006
  3. ncbi The TCA cycle and tumorigenesis: the examples of fumarate hydratase and succinate dehydrogenase
    Patrick J Pollard
    Molecular and Population Genetics Laboratory, Cancer Research UK, Lincoln s Inn Fields, London, UK
    Ann Med 35:632-9. 2003
  4. ncbi 7q deletion mapping and expression profiling in uterine fibroids
    Sakari Vanharanta
    Department of Medical Genetics, University of Helsinki, PO Box 63 Haartmaninkatu 8, Biomedicum Helsinki, FIN 00014, Finland
    Oncogene 24:6545-54. 2005
  5. ncbi Definition of a minimal region of deletion of chromosome 7 in uterine leiomyomas by tiling-path microarray CGH and mutation analysis of known genes in this region
    Sakari Vanharanta
    Department of Medical Genetics, Biomedicum Helsinki, University of Helsinki, Helsinki, Finland
    Genes Chromosomes Cancer 46:451-8. 2007
  6. doi Single base mutation in the fumarate hydratase gene leading to segmental cutaneous leiomyomatosis
    Eva Huter
    Acta Derm Venereol 88:63-5. 2008

Collaborators

  • Patrick J Pollard
  • Sakari Vanharanta
  • Eva Huter
  • Auli Karhu
  • Jari Sj√∂berg
  • Lauri A Aaltonen
  • Uta Jappe
  • Wolfgang Hartschuh
  • Alexander Enk
  • Mona El-Bahrawy
  • Rainer Lehtonen
  • Cordelia Langford
  • Ian P M Tomlinson
  • Zephne Van der Spuy
  • Paivi Laiho
  • Johanna Arola
  • Kristiina Aittomaki
  • Diego Arango
  • Ian P Tomlinson

Detail Information

Publications6

  1. ncbi Dercum's disease
    Noel C Wortham
    Molecular and Population Genetics Laboratory, Cancer Research UK, London, England
    Skinmed 4:157-62; quiz 163-4. 2005
    ..Here, the authors review the literature to date, including some information from their own studies. In particular, the authors will look at the different strands of evidence pointing to the pathological mechanism of the disorder...
  2. ncbi Aberrant expression of apoptosis proteins and ultrastructural aberrations in uterine leiomyomas from patients with hereditary leiomyomatosis and renal cell carcinoma
    Noel C Wortham
    Molecular and Population Genetics Laboratory, Cancer Research UK, London, United Kingdom
    Fertil Steril 86:961-71. 2006
    ..To examine differences between sporadic and familial uterine leiomyomata related to expression of apoptosis-related proteins and tumor ultrastructure...
  3. ncbi The TCA cycle and tumorigenesis: the examples of fumarate hydratase and succinate dehydrogenase
    Patrick J Pollard
    Molecular and Population Genetics Laboratory, Cancer Research UK, Lincoln s Inn Fields, London, UK
    Ann Med 35:632-9. 2003
    ..It remains entirely possible, however, that the underlying mechanisms of tumorigenesis in these sporadic tumours are the same as those in the Mendelian syndromes...
  4. ncbi 7q deletion mapping and expression profiling in uterine fibroids
    Sakari Vanharanta
    Department of Medical Genetics, University of Helsinki, PO Box 63 Haartmaninkatu 8, Biomedicum Helsinki, FIN 00014, Finland
    Oncogene 24:6545-54. 2005
    ..The presence or absence of 7q-deletions did not dramatically affect the global expression pattern of the tumours; changes, however, were observed in genes related to vesicular transport and nucleic acid binding...
  5. ncbi Definition of a minimal region of deletion of chromosome 7 in uterine leiomyomas by tiling-path microarray CGH and mutation analysis of known genes in this region
    Sakari Vanharanta
    Department of Medical Genetics, Biomedicum Helsinki, University of Helsinki, Helsinki, Finland
    Genes Chromosomes Cancer 46:451-8. 2007
    ..We have refined the minimum deleted region at 7q22.3-q31 to 2.79 Mbp and identified a second region of deletion at 7q34. However, we identified no pathogenic coding variation...
  6. doi Single base mutation in the fumarate hydratase gene leading to segmental cutaneous leiomyomatosis
    Eva Huter
    Acta Derm Venereol 88:63-5. 2008