Research TopicsGenomes and GenesSpecies | Matthew L SmithSummaryAffiliation: Cancer Research UK Country: UK Publications
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Detail Information
Publications
Mutation of CEBPA in familial acute myeloid leukemiaMatthew L Smith
Medical Oncology Unit, Cancer Research UK, Barts and the London School of Medicine and Dentistry, St Bartholomew s Hospital, West Smithfield, London
N Engl J Med 351:2403-7. 2004..All three patients are currently well, with no abnormalities in the bone marrow. CEBPA mutation is apparently the primary event in the development of AML in this family...
Development of a human acute myeloid leukaemia screening panel and consequent identification of novel gene mutation in FLT3 and CCND3Matthew L Smith
Cancer Research UK Medical Oncology Unit, Charterhouse Square, Barts and the London School of Medicine and Dentistry, London
Br J Haematol 128:318-23. 2005..A 51-bp deletion was detected in CCND3 in a patient with normal karyotype AML. This validated panel now provides an important tool to evaluate other candidate genes in the genesis of myeloid malignancy...
Mutations of CEBPA in acute myeloid leukemia FAB types M1 and M2Jennifer Snaddon
Cancer Research UK Medical Oncology Unit, Charterhouse Square, St Bartholomew s Hospital, London, United Kingdom
Genes Chromosomes Cancer 37:72-8. 2003..In conclusion, mutation of CEBPA is a recurrent finding in AML and appears specific to the intermediate cytogenetic risk group patients...
Development of a quantitative real-time polymerase chain reaction method for monitoring CEBPA mutations in normal karyotype acute myeloid leukaemiaLan-Lan Smith
Br J Haematol 133:103-5. 2006
