Research Topics
Genomes and GenesSpecies | Ying LiuSummaryAffiliation: Cancer Research UK Country: UK Publications
| Collaborators
|
Detail Information
Publications
The human homologue of unc-93 maps to chromosome 6q27 - characterisation and analysis in sporadic epithelial ovarian cancerYing Liu
Cancer Research UK Molecular Oncology Laboratories, Weatherall Institute of Molecular Medicine, John Radcliffe Hospital, Headington, Oxford, OX3 9DS, UK
BMC Genet 3:20. 2002..To accelerate the identification of genes, we sequenced the entire contig of approximately 1.1 Mb. Seven genes were identified within the region of allele loss between D6S264 and D6S149...
Physical and transcript map of the region between D6S264 and D6S149 on chromosome 6q27, the minimal region of allele loss in sporadic epithelial ovarian cancerYing Liu
ICRF Molecular Oncology Laboratories, John Radcliffe Hospital, Headington, Oxford, OX3 9DS, UK
Oncogene 21:387-99. 2002..Clonogenic assays were performed by transfecting the full-length gene in to ovarian cancer cell lines and no suppression of growth was observed...
Gastrointestinal differentiation marker Cytokeratin 20 is regulated by homeobox gene CDX1Carol W M Chan
Cancer and Immunogenetics Laboratory, Weatherall Institute of Molecular Medicine, John Radcliffe Hospital, University of Oxford, OX3 9DS, United Kingdom
Proc Natl Acad Sci U S A 106:1936-41. 2009..This could, therefore, explain the relatively frequent down regulation of CDX1 in colorectal carcinomas by hypermethylation...
Analysis of P53 mutations and their expression in 56 colorectal cancer cell linesYing Liu
Cancer Research UK Cancer and Immunogenetics Laboratory, Weatherall Institute of Molecular Medicine, John Radcliffe Hospital, Oxford OX3 9DS, UK
Proc Natl Acad Sci U S A 103:976-81. 2006....
Tumour suppressor genes in sporadic epithelial ovarian cancerYing Liu
ICRF Molecular Oncology Laboratories, Institute of Molecular Medicine, John Radcliffe Hospital, Headington, Oxford OX3 9DS, UK
Reproduction 123:341-53. 2002..Further research is warranted to understand fully their contribution to the pathogenesis of sporadic ovarian cancer...
Mutations in the AXIN1 gene in advanced prostate cancerGeorge W Yardy
Cancer Research UK, Cancer and Immunogenetics Laboratory, Weatherall Institute of Molecular Medicine, John Radcliffe Hospital, Oxford, UK
Eur Urol 56:486-94. 2009..Such mutations are rare in hepatocellular carcinomas and medulloblastomas with Wnt pathway dysfunction, and there, mutation in genes for other Wnt molecules, such as Axin, is more frequently found...
The Bro1-domain protein, EGO-2, promotes Notch signaling in Caenorhabditis elegansYing Liu
Department of Biology, Syracuse University, 108 College Place, Syracuse, NY 13244, USA
Genetics 176:2265-77. 2007..We document a complex phenotypic interaction between ego-2 and alx-1, consistent with their relationship being antagonistic with respect to some developmental processes and agonistic with respect to others...
Yeast cells lacking the ARV1 gene harbor defects in sphingolipid metabolism. Complementation by human ARV1Evelyn Swain
Department of Biochemistry, MCP Hahnemann University, Philadelphia, Pennsylvania 19102, USA
J Biol Chem 277:36152-60. 2002..We hypothesize that in eukaryotic cells, Arv1p functions in the sphingolipid metabolic pathway perhaps as a transporter of ceramides between the endoplasmic reticulum and Golgi...
Expression and antibody preparation of POU transcription factor qBrn-1Lei Lan
State Key Laboratory of Brain and Cognitive Sciences, Institute of Biophysics, Chinese Academy of Sciences, 15 Datun Road, Beijing 100101, China
Protein Pept Lett 14:7-11. 2007....
Creation of engineered human embryonic stem cell lines using phiC31 integraseBhaskar Thyagarajan
Invitrogen Corporation, Carlsbad, California 92008, USA
Stem Cells 26:119-26. 2008..Our results demonstrate the utility of phiC31 integrase to target pseudo-attP sites in hESC and show that integrase-mediated site-specific integration can efficiently create stably expressing engineered human embryonic stem cell clones...
Investigate the role of PTEN in chemotaxis of human breast cancer cellsWuzhou Wan
Beijing National Laboratory for Molecular Sciences BNLMS, Department of Chemical Biology, and State Key Laboratory of Molecular Dynamic and Stable Structures, College of Chemistry, Peking University, Beijing, China
Cell Signal 19:2227-36. 2007..Taken together, our data show that PTEN plays a non-redundant role in EGF-induced chemotaxis of human breast cancer cells, and an optimal level of PTEN is required in these responses...
KLF4 regulates the expression of interleukin-10 in RAW264.7 macrophagesJunwen Liu
Laboratory of Shock, Department of Pathophysiology, Xiangya School of Medicine, Central South University, 110 Xiangya Road, Changsha, Hunan 410008, People s Republic of China
Biochem Biophys Res Commun 362:575-81. 2007..The overexpression of KLF4 promoted the transcription and DNA binding activities of KLF4 to the IL-10 promoter. These results indicate that KLF4 plays an important role in regulating the expression of IL-10...
Complete protein linkage map between the P2 and P3 non-structural proteins of poliovirusJiang Yin
Department of Molecular Genetics and Microbiology, School of Medicine, Stony Brook University, Stony Brook, NY 11794, USA
J Gen Virol 88:2259-67. 2007..The possible biological implication of the interactions observed in the yeast two-hybrid system will be discussed...
Histone H2AX is a mediator of gastrointestinal stromal tumor cell apoptosis following treatment with imatinib mesylateYing Liu
Molecular Virology Program, University of Pittsburgh Cancer Institute, Pennsylvania 15213, USA
Cancer Res 67:2685-92. 2007..Our results underscore the importance of H2AX as a human tumor suppressor protein, provide mechanistic insights into imatinib-induced tumor cell apoptosis and establish H2AX as a novel target in cancer therapy...
The involvement of lipid rafts in epidermal growth factor-induced chemotaxis of breast cancer cellsYing Liu
Beijing National Laboratory for Molecular Sciences BNLMS and Department of Chemical Biology, College of Chemistry and Molecular Engineering, Peking University, Beijing, China
Mol Membr Biol 24:91-101. 2007..Taken together, our study indicated that integrity of lipid rafts was critical in EGF-induced chemotaxis of human breast cancer cells...
Improvement of the sensitivity and resolution of PCR-SSCP analysis with optimized primer concentrations in PCR productsXilin Zhu
National Laboratory of Medical Molecular Biology, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences, China
J Genet 85:233-5. 2006
Qualification of embryonal carcinoma 2102Ep as a reference for human embryonic stem cell researchRichard Josephson
GlobalStem, Inc, 6 Taft Court, Rockville, Maryland 20850, USA
Stem Cells 25:437-46. 2007..On the basis of global gene and microRNA expression, 2102Ep is somewhat less similar to hESC than the alternatives; however, 2102Ep expresses more hESC-associated microRNAs than NTERA-2 does, and fewer markers of differentiated fates...
Mechanistic studies of a peptidic GRP78 ligand for cancer cell-specific drug deliveryYing Liu
The Skaggs Institute for Chemical Biology and Departments of Chemistry and Immunology, Worm Institute of Research and Medicine, and Department of Molecular and Experimental Medicine, The Scripps Research Institute, La Jolla, California 92037, USA
Mol Pharm 4:435-47. 2007....
Comparative pharmacokinetics and distribution kinetics in brain of phencynonate enantiomers in ratsYuying Kou
Department of Pharmacology, School of Chemical Biology and Pharmaceutical Sciences, Capital Medical University, Youanmen, Beijing, China
Int J Pharm 353:88-94. 2008..Therefore, stereoselective disposition of phencynonate isomers was not obviously observed in rat...
A large-scale proteomic analysis of human embryonic stem cellsThomas C Schulz
Buck Institute for Age Research, 8001 Redwood Blvd, Novato, CA, USA
BMC Genomics 8:478. 2007..These analyses are only partly predictive of protein expression however, and do not shed light on post-translational regulation, leaving a large gap in our knowledge of the biology of pluripotent stem cells...
Development and validation of a liquid chromatography/electrospray ionization time-of-flight mass spectrometry method for relative and absolute quantification of steroidal alkaloids in Fritillaria speciesJian Liang Zhou
Department of Pharmacognosy, China Pharmaceutical University, No 24, Tongjia Lane, Nanjing 210009, China
J Chromatogr A 1177:126-37. 2008..6-110.0% (average 98.5%) suggesting that it is feasible to quantify steroidal alkaloids by the proposed relative quantitative determination method within acceptable errors...
A cryptographic approach to securely share and query genomic sequencesMurat Kantarcioglu
Department of Computer Science, University of Texas, Dallas, TX 75080 3021 USA
IEEE Trans Inf Technol Biomed 12:606-17. 2008..The framework can be implemented on top of existing information and network technologies in biomedical environments...
Azithromycin quantitation in human plasma by high-performance liquid chromatography coupled to electrospray mass spectrometry: application to bioequivalence studyFengguo Xu
Key Laboratory of Drug Quality Control and Pharmacovigilance China Pharmaceutical University, Ministry of Education, Nanjing, 210009, PR China
J Chromatogr Sci 46:479-84. 2008..The limit of detection and quantitation are 2 ng/mL and 5 ng/mL, respectively. The proposed method enables the unambiguous identification and quantitation of azithromycin for pharmacokinetic, bioavailability, or bioequivalence studies...
Identification of parameters required for efficient lentiviral vector transduction and engraftment of human cord blood CD34(+) NOD/SCID-repopulating cellsYing Liu
Department of Microbiology and Immunology and the Walther Oncology Center, Indiana University School of Medicine, Indianapolis, IN 46202, USA
Exp Hematol 36:947-56. 2008..To optimize culture and transduction conditions, we compared various lengths of time for prestimulation before transduction, transduction duration, and posttransduction cell culture...
An HPLC method for determination of oridonin in rabbits using isopsoralen as an internal standard and its application to pharmacokinetic studies for oridonin-loaded nanoparticlesYinghao Mei
Department of Pharmaceutics, Shanghai University of Traditional Chinese Medicine, Shanghai, China
J Chromatogr B Analyt Technol Biomed Life Sci 869:138-41. 2008....
Multiple intrinsically disordered sequences alter DNA binding by the homeodomain of the Drosophila hox protein ultrabithoraxYing Liu
Department of Biochemistry and Cell Biology, Rice University, Houston, TX 77005, USA
J Biol Chem 283:20874-87. 2008..The amino acid sequences of I2 and much of the I1 and R regions vary significantly among Ultrabithorax orthologues, potentially diversifying Hox-DNA interactions...
Bioequivalence assessment of two formulations of spironolactone in Chinese healthy male volunteersFeng Guo Xu
Key Laboratory of Drug Quality Control and Pharmacovigilance, China Pharmaceutical University, Ministry of Education, Nanjing, PR China
Arzneimittelforschung 58:117-21. 2008..This study shows that the test formulation is bioequivalent to the reference formulation for spironolactone and its main active metabolite canrenone...
Quantitative determination of nitrendipine in human plasma using high-performance liquid chromatography-mass spectrometryYing Liu
Key Laboratory of Drug Quality Control and Pharmacovigilance China Pharmaceutical University, Ministry of Education, Nanjing, PR China
Arzneimittelforschung 58:111-6. 2008..This validated method was successfully applied to the evaluation of the pharmacokinetic profiles of nitrendipine tablets administered to 8 Chinese healthy volunteers...
Analysis of correlated mutations in HIV-1 protease using spectral clusteringYing Liu
Department of Computational Biology, School of Medicine, University of Pittsburgh, PA 15232, USA
Bioinformatics 24:1243-50. 2008....
Cyclic adenosine 3',5'-monophosphate responsive element binding protein phosphorylation is required but not sufficient for activation of corticotropin-releasing hormone transcriptionYing Liu
Section on Endocrine Physiology, Developmental Endocrinology Branch, National Institute of Child Health and Human Development, National Institutes of Health, 10 Center Drive, Bethesda, MD 20892, USA
Endocrinology 149:3512-20. 2008..In addition, the data indicate that phosphorylated CREB is essential but not sufficient for activation of CRH transcription, suggesting that full promoter stimulation requires the interaction of phosphorylated CREB with a coactivator...
Rapid simultaneous quantification of five active constituents in rat plasma by high-performance liquid chromatography/tandem mass spectrometry after oral administration of Da-Cheng-Qi decoctionFengguo Xu
Key Laboratory of Drug Quality Control and Pharmacovigilance China Pharmaceutical University, Ministry of Education, Nanjing 210009, China
J Pharm Biomed Anal 47:586-95. 2008....
The sphingolipid long-chain base-Pkh1/2-Ypk1/2 signaling pathway regulates eisosome assembly and turnoverGuangzuo Luo
Department of Molecular and Cellular Biochemistry, University of Kentucky College of Medicine, Lexington, Kentucky 40536, USA
J Biol Chem 283:10433-44. 2008..Eisosomes then control endocytosis to align the composition and function of the plasma membrane to match demand...
Preparation and evaluation of self-microemulsifying drug delivery system of oridoninPing Zhang
School of Pharmacy, Shanghai University of Traditional Chinese Medicine, Shanghai 210203, PR China
Int J Pharm 355:269-76. 2008..The absorption of oridonin from SMEDDS showed a 2.2-fold increase in relative bioavailability compared with that of the suspension. Our studies demonstrated the promising use of SMEDDS for the delivery of oridonin by the oral route...
Development of a microscopy-based assay for protein kinase Czeta activation in human breast cancer cellsCaijie Zhao
Beijing National Laboratory for Molecular Sciences, Department of Chemical Biology and State Key Laboratory of Molecular Dynamic and Stable Structures, College of Chemistry, Peking University, Beijing 100871, China
Anal Biochem 362:8-15. 2007..This assay can be used in screening for inhibitors of PKCzeta activation, which is critically required for cancer cell chemotaxis...
Effect of DPC4 gene on invasion and metastasis of colorectal carcinoma cellsDe Sheng Xiao
Department of Pathology, Xiangya School of Medicine, Central South University, Changsha 410078, China
Acta Biochim Biophys Sin (Shanghai) 38:883-92. 2006..DPC4 may inhibit the proliferation of colon cancer cell by restraining growth and inducing apoptosis, and the invasion and metastasis of colorectal carcinoma cells. MMP-9 may be one of the downstream target genes regulated by DPC4...
The C-terminal hydrophobic domain of hepatitis C virus RNA polymerase NS5B can be replaced with a heterologous domain of poliovirus protein 3AHaekyung Lee
Department of Molecular Genetics and Microbiology, School of Medicine, Stony Brook University, Stony Brook, NY 11794, USA
J Virol 80:11343-54. 2006..This suggests that specific interactions between the NS5B hydrophobic domain and other membrane-bound factors may not play a decisive role in HCV replication...
Inhibition of hemangiogenesis and lymphangiogenesis after normal-risk corneal transplantation by neutralizing VEGF promotes graft survivalClaus Cursiefen
Schepens Eye Research Institute, Department of Ophthalmology, Harvard Medical School, Boston, Massachusetts 02114, USA
Invest Ophthalmol Vis Sci 45:2666-73. 2004....
Recursion equations in predicting band width under gradient elutionHeng Liang
The Key Laboratory of Biomedical Information Engineering of Education Ministry, Separation Science Institute, Xi an Jiaotong University, Xi an 710049, People s Republic of China
J Chromatogr A 1040:19-31. 2004..Recursion equations and literature equations were used in dealing with same experimental data in RP-HPLC, and the comparison results show that the recursion equations can accurately predict band width under gradient elution...
Ecotoxicological evaluation of 4-aminobiphenyl using a test batteryJiangning Chen
State Key Laboratory of Pharmaceutical Biotechnology, Department of Biochemistry, Nanjing University, Nanjing 210093, China
Ecotoxicol Environ Saf 58:104-9. 2004....
Attenuation of zinc-induced neuronal death by the interaction of growth inhibitory factor with Rab3A in rat hippocampal neuronsYing Liu
National Key Laboratory of Protein Engineering, College of Life Sciences, Peking University, Beijing 100871, China
Neurosci Lett 358:149-52. 2004..This result was supported by both Annexin -V FITC/propidium dual staining and chromosomal DNA analysis. These findings suggest that GIF may inhibit Zn(2+)-induced neuronal death via its interaction with Rab3A...
Mutagenesis of the putative sterol-sensing domain of yeast Niemann Pick C-related protein reveals a primordial role in subcellular sphingolipid distributionKrishnamurthy Malathi
Institute of Human Nutrition, Columbia University Medical Center, 630 W 168 St, New York, NY 10032, USA
J Cell Biol 164:547-56. 2004..We propose that the primordial function of these proteins is to recycle sphingolipids and that defects in this process in higher eukaryotes secondarily result in cholesterol accumulation...
The effects of a growth-inhibiting tripeptide, acetylGlu-Ser-GlyNH2 (Ac-ESG), on gene expression and cell cycle progression of two lymphoma cell linesYing Liu
Institute of Pediatric Research, National Hospital, University of Oslo, N 0027 Oslo, Norway
Anticancer Res 23:3159-65. 2003..In this paper we describe the effects of Ac-ESG on growth-related gene expression and cell cycle progression in two lymphoma cell lines, Ramos and Molt, representing B and T lymphocytes, respectively...
Identification of a novel integrin alpha 6 beta 1 binding site in the angiogenic inducer CCN1 (CYR61)Shr Jeng Leu
Department of Molecular Genetics, University of Illinois College of Medicine, Chicago, Illinois 60607 7170, USA
J Biol Chem 278:33801-8. 2003....
[Study on mechanisms of human gastric carcinoma cells apoptosis induced by genistein]Danfeng Song
Public Health School, Harbin Medical University, Harbin 150001, China
Wei Sheng Yan Jiu 32:128-30. 2003..These indicated that genistein could induce the apoptosis of gastric carcinoma cells. The inhibition of the expression of mutant p53 and enhance of the protein expression of Caspase-3 would be possible mechanism...
Enhancement of antitumor effect of cisplatin against human ovarian carcinoma cells by mifepristone in vivoYing Liu
Department of Obstetrics and Gynecology, Zhujiang Hospital, First Military Medical University, Guangzhou 510282, China
Di Yi Jun Yi Da Xue Xue Bao 23:242-4. 2003..CONCLUSION: At a non-toxic dose, RU486 may enhance the sensitivity of tumor cells to cisplatin in vivo, possibly through the mechanism of inhibiting GcS expression at the mRNA level...
[Effect of isoflavone on human breast cancer cell line MCF-7 and its probable mechanism]Qingwei Fang
Department of Public Health, Harbin Medical University, Harbin 150001, China
Wei Sheng Yan Jiu 31:367-9. 2002..Western Blotting showed that isoflavone increased iNOS protein expression. These results suggested that isoflavone significantly inhibited the MCF-7 growth and induced cell apoptosis by regulating iNOS gene expression...
[Inhibitory effects of genistein on the synthesis of DNA and the protein expression of cyclin D1 in human gastric carcinoma cell-line]Danfeng Song
Public Health School, Harbin Medical University, Harbin 150001, China
Wei Sheng Yan Jiu 31:106-8. 2002....
Synthesis and cytotoxicity of 2alpha-amido docetaxel analoguesWei Shuo Fang
Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, 1 Xian Nong Tan Street, Beijing 100050, PR China
Bioorg Med Chem Lett 12:1543-6. 2002..Change of 2-benzoate to 2-benzamide may not improve their activities to drug-resistant cell lines...
Targeted mutagenesis of the angiogenic protein CCN1 (CYR61). Selective inactivation of integrin alpha6beta1-heparan sulfate proteoglycan coreceptor-mediated cellular functionsShr Jeng Leu
Department of Biochemistry and Molecular Genetics, University of Illinois at Chicago College of Medicine, 60607 7170, USA
J Biol Chem 279:44177-87. 2004....
Effects of protein kinase C on M-phase promoting factor in early development of fertilized mouse eggsBing Zhi Yu
Department of Biochemistry, China Medical University, Shenyang, 110001, People s Republic of China
Cell Biochem Funct 22:291-8. 2004..These results clearly indicate that PKC may affect the progression of the cell cycle through post-translational modification of MPF activity...
The acidic C-terminal domain stabilizes the chaperone function of protein disulfide isomeraseRui Tian
Laboratory of Visual Information Processing, Chinese Academy of Sciences, Beijing, China
J Biol Chem 279:48830-5. 2004..This suggests that domain c is required for the stabilization and maintenance of the chaperone function of PDI under extreme conditions...
Determination of thiencynonate by liquid chromatographic-mass spectrometry and its application to pharmacokinetics in ratsYanxia Xu
Department of Pharmacology, School of Chemical Biology and Pharmaceutical Sciences, Capital University of Medical Sciences, Beijing 100069, PR China
J Pharm Biomed Anal 42:149-54. 2006..47 to 9.28% in rat plasma. Extraction recoveries were in the range of 67.63-76.76% in plasma. This method was successfully applied to the identification and quantification of thiencynonate in pharmacokinetic studies...
Massively parallel signature sequencing profiling of fetal human neural precursor cellsJingli Cai
Stem Cell Biology Unit/Laboratory of Neurosciences, National Institute on Aging Intramural Research Program, National Institutes of Health, Baltimore, MD 21224, USA
Stem Cells Dev 15:232-44. 2006..In addition, our results allow us to identify novel genes expressed in fNPCs and provide a detailed profile of fNPCs...
Expression of qBrn-1, a new member of the POU gene family, in the early developing nervous system and embryonic kidneyLei Lan
The State Key Laboratory of Brain and Cognitive Sciences, Institute of Biophysics, The Chinese Academy of Sciences, Beijing 100101, People's Republic of China
Dev Dyn 235:1107-14. 2006..The distinct dynamic expression patterns of qBrn-1 and qBrn-2 indicate multiple roles of the class III POU genes in quail neurogenesis and organogenesis...
Essential role for Rac in heregulin beta1 mitogenic signaling: a mechanism that involves epidermal growth factor receptor and is independent of ErbB4Chengfeng Yang
Department of Pharmacology, University of Pennsylvania School of Medicine, 816 Biomedical Research Building II III, 421 Curie Blvd, Philadelphia, PA 19104 6160, USA
Mol Cell Biol 26:831-42. 2006....
Serum proteomic pattern analysis for early cancer detectionYing Liu
Laboratory for Bioinformatics and Medical Informatics, Department of Computer Science, Erik Jonsson School of Engineering and Computer Science, University of Texas at Dallas, Richardson, 75083, USA
Technol Cancer Res Treat 5:61-6. 2006..82. When redial kernel was applied to either of the two data sets, all the samples were predicted as cancer samples, with a sensitivity of 1 and a specificity of 0. Furthermore, feature selection did not improve SVM performance...
[Identification of drought tolerant germplasm and inheritance and QTL mapping of related root traits in soybean (Glycine max (L.) Merr.)]Ying Liu
National Center for Soybean Improvement, National Key Laboratory for Crop Genetics and Germplasm Enhancement, Soybean Research Institute of Nanjing Agricultural University, Nanjing 210095, China
Yi Chuan Xue Bao 32:855-63. 2005..The results of segregation analysis and QTL mapping appeared pretty consistent with each other, which could be used as a demonstration of each other...
Genetic variant characterization in intron 4 of the surfactant protein B geneAaron Hamvas
Division of Newborn Medicine, Edward Mallinckrodt Department of Pediatrics, Washington University School of Medicine and St Louis Children s Hospital, St Louis, Missouri, USA
Hum Mutat 26:494-5. 2005..7, 95% CI 1.0-7.2). Reliable characterization of genetic variants in intron 4 requires both a high fidelity polymerase and sequencing of variant alleles...
Critical role of protein kinase C betaII in activation of mast cells by monomeric IgEYing Liu
Department of Physiological Chemistry, Graduate School of Pharmaceutical Sciences, Kyoto University, Sakyo ku, Kyoto 606 8501, Japan
J Biol Chem 280:38976-81. 2005..Expression of PKCbetaII/T500V was found not to affect the antigen-induced responses. These results suggest that PKCbetaII plays a critical role in monomeric IgE responses, but not in antigen responses...
Saturated fat-rich diet enhances selective uptake of LDL cholesteryl esters in the arterial wallToru Seo
Department of Pediatrics, Institute of Human Nutrition, College of Physicians and Surgeons, Columbia University, New York, New York 10032, USA
J Clin Invest 115:2214-22. 2005..These studies suggest that arterial LDL-CE delivery via SU can be an important mechanism in vivo and that dietary influences on arterial LPL levels and atherogenesis modulate arterial LDL-CE delivery, cholesterol deposition, and SU...
Establishment of a new embryonic stem cell line derived from C57BL/6 mouse expressing EGFP ubiquitouslyRie Shimizukawa
Laboratory Animal Resource Center, University of Tsukuba, Tsukuba, Ibaraki, Japan
Genesis 42:47-52. 2005..The B6G-2 cell line is freely available from the BioResource Center, RIKEN Tsukuba Institute (http://www.brc.riken.jp/lab/cell/english/)...
[Chiral separation of beta-receptor blockers and analogs on novel norvancomycin-bonded chiral stationary phase]Guosheng Ding
Dalian Institute of Chemical Physics, The Chinese Academy of Sciences, Dalian 116012, China
Se Pu 22:386-9. 2004....
Active learning with support vector machine applied to gene expression data for cancer classificationYing Liu
Georgia Institute of Technology, College of Computing, Atlanta, Georgia 30322, USA
J Chem Inf Comput Sci 44:1936-41. 2004..In active learning the areas under the receiver operating characteristic (ROC) curves were over 0.81, while in passive learning the areas under the ROC curves were below 0.50...
HIV-1 Tat protein-mediated transactivation of the HIV-1 long terminal repeat promoter is potentiated by a novel nuclear Tat-interacting protein of 110 kDa, Tip110Ying Liu
Department of Microbiology and Immunology, Walther Oncology Center, Indiana University School of Medicine, Indianapolis, Indiana 46202, USA
J Biol Chem 277:23854-63. 2002..Taken together, these data demonstrate that Tip110 regulates Tat transactivation activity through direct interaction, and suggest that Tip110 is an important cellular factor for HIV-1 gene expression and viral replication...
