- Colonic crypt organization and tumorigenesisAdam Humphries
Histopathology Lab, London Research Institute, Cancer Research UK, 44 Lincoln s Inn Fields, London WC2A 3PX, UK
Nat Rev Cancer 8:415-24. 2008..Recent advances in our understanding of crypt biology, including how mutations in stem cells become fixed and expand within the epithelium, has led to new theories on the origins of colonic adenomas and cancers...
- Stem cells and inflammation in the intestineAdam Humphries
Histopathology Unit, London Research Institute, Cancer Research UK, London, UK
Recent Results Cancer Res 185:51-63. 2011..This work has also shown how crypts themselves divide and expand in the human colon...