S W Duffy

Summary

Affiliation: Cancer Research UK
Country: UK

Publications

  1. pmc Complexities in the estimation of overdiagnosis in breast cancer screening
    S W Duffy
    Cancer Research UK Centre for Epidemiology Mathematics and Statistics, Wolfson Institute of Preventive Medicine, Charterhouse Square, London EC1 M 6BQ, UK
    Br J Cancer 99:1176-8. 2008
  2. ncbi Screening for breast cancer
    Stephen W Duffy
    Cancer Research UK, Department of Epidemiology, Mathematics and Statistics, Wolfson Institute of Preventive Medicine, Queen Mary University of London, London EC1M 6BQ, UK
    Surg Oncol Clin N Am 14:671-97. 2005
  3. pmc Overdiagnosis and overtreatment of breast cancer: estimates of overdiagnosis from two trials of mammographic screening for breast cancer
    Stephen W Duffy
    Cancer Research UK Department of Epidemiology, Mathematics and Statistics, Wolfson Institute of Preventive Medicine, Queen Mary College, University of London, London, UK
    Breast Cancer Res 7:258-65. 2005
  4. pmc Overdiagnosis and overtreatment of breast cancer: overdiagnosis and overtreatment in service screening
    Eugenio Paci
    Unit of Clinical and Descriptive Epidemiology, CSPO, Research Institute of the Tuscany, Via di SanSalvi, Florence, Italy
    Breast Cancer Res 7:266-70. 2005
  5. pmc Variable size computer-aided detection prompts and mammography film reader decisions
    Fiona J Gilbert
    Division of Applied Medicine, School of Medicine and Dentistry, University of Aberdeen, Lilian Sutton Building, Foresterhill, Aberdeen AB25 2ZD, UK
    Breast Cancer Res 10:R72. 2008
  6. pmc Imputation of a true endpoint from a surrogate: application to a cluster randomized controlled trial with partial information on the true endpoint
    Richard M Nixon
    MRC Biostatistics Unit, Institute of Public Health, Robinson Way, Cambridge, CB2 2SR, UK
    BMC Med Res Methodol 3:17. 2003
  7. pmc Interaction of dense breast patterns with other breast cancer risk factors in a case-control study
    S W Duffy
    Cancer Research UK, Department of Epidemiology, Mathematics and Statistics, Wolfson Institute of Preventive Medicine, Charterhouse Square, London EC1M 6BQ, UK
    Br J Cancer 91:233-6. 2004
  8. pmc A simple model for potential use with a misclassified binary outcome in epidemiology
    S W Duffy
    Cancer Research UK Department of Epidemiology, Mathematics and Statistics, Wolfson Institute of Preventive Medicine, Queen Mary University of London, UK
    J Epidemiol Community Health 58:712-7. 2004
  9. pmc Visually assessed breast density, breast cancer risk and the importance of the craniocaudal view
    Stephen W Duffy
    Department of Epidemiology, Mathematics and Statistics, Wolfson Institute of Preventive Medicine, Charterhouse Square, London EC1M 6BQ, UK
    Breast Cancer Res 10:R64. 2008
  10. ncbi Tumor size and breast cancer detection: what might be the effect of a less sensitive screening tool than mammography?
    Stephen W Duffy
    Cancer Research UK Center for Epidemiology, Mathematics, and Statistics, Wolfson Institute of Preventive Medicine, London, United Kingdom
    Breast J 12:S91-5. 2006

Detail Information

Publications76

  1. pmc Complexities in the estimation of overdiagnosis in breast cancer screening
    S W Duffy
    Cancer Research UK Centre for Epidemiology Mathematics and Statistics, Wolfson Institute of Preventive Medicine, Charterhouse Square, London EC1 M 6BQ, UK
    Br J Cancer 99:1176-8. 2008
    ..We illustrate this using an example of analysis of breast cancer incidence data from Sweden...
  2. ncbi Screening for breast cancer
    Stephen W Duffy
    Cancer Research UK, Department of Epidemiology, Mathematics and Statistics, Wolfson Institute of Preventive Medicine, Queen Mary University of London, London EC1M 6BQ, UK
    Surg Oncol Clin N Am 14:671-97. 2005
    ....
  3. pmc Overdiagnosis and overtreatment of breast cancer: estimates of overdiagnosis from two trials of mammographic screening for breast cancer
    Stephen W Duffy
    Cancer Research UK Department of Epidemiology, Mathematics and Statistics, Wolfson Institute of Preventive Medicine, Queen Mary College, University of London, London, UK
    Breast Cancer Res 7:258-65. 2005
    ..Our results suggest that overdiagnosis in mammography screening is a minor phenomenon, but further studies with very large numbers are required for more precise estimation...
  4. pmc Overdiagnosis and overtreatment of breast cancer: overdiagnosis and overtreatment in service screening
    Eugenio Paci
    Unit of Clinical and Descriptive Epidemiology, CSPO, Research Institute of the Tuscany, Via di SanSalvi, Florence, Italy
    Breast Cancer Res 7:266-70. 2005
    ..The overtreatment issue is discussed in terms of appropriateness of effective treatment considering the question of chemotherapy in very early stages and the use of breast conserving surgery...
  5. pmc Variable size computer-aided detection prompts and mammography film reader decisions
    Fiona J Gilbert
    Division of Applied Medicine, School of Medicine and Dentistry, University of Aberdeen, Lilian Sutton Building, Foresterhill, Aberdeen AB25 2ZD, UK
    Breast Cancer Res 10:R72. 2008
    ....
  6. pmc Imputation of a true endpoint from a surrogate: application to a cluster randomized controlled trial with partial information on the true endpoint
    Richard M Nixon
    MRC Biostatistics Unit, Institute of Public Health, Robinson Way, Cambridge, CB2 2SR, UK
    BMC Med Res Methodol 3:17. 2003
    ..Data are only available for the true end point on a sub set of the practices, but there are surrogate data for almost all of the audited practices and for most of the remaining practices...
  7. pmc Interaction of dense breast patterns with other breast cancer risk factors in a case-control study
    S W Duffy
    Cancer Research UK, Department of Epidemiology, Mathematics and Statistics, Wolfson Institute of Preventive Medicine, Charterhouse Square, London EC1M 6BQ, UK
    Br J Cancer 91:233-6. 2004
    ..The results are consistent with dense breast patterns as a marker for hormonal modification of breast cancer risk...
  8. pmc A simple model for potential use with a misclassified binary outcome in epidemiology
    S W Duffy
    Cancer Research UK Department of Epidemiology, Mathematics and Statistics, Wolfson Institute of Preventive Medicine, Queen Mary University of London, UK
    J Epidemiol Community Health 58:712-7. 2004
    ..A method of correction of risk estimates for misclassification of a binary disease outcome is developed here...
  9. pmc Visually assessed breast density, breast cancer risk and the importance of the craniocaudal view
    Stephen W Duffy
    Department of Epidemiology, Mathematics and Statistics, Wolfson Institute of Preventive Medicine, Charterhouse Square, London EC1M 6BQ, UK
    Breast Cancer Res 10:R64. 2008
    ..A particularly strong association with risk has been observed when density is measured using interactive threshold software. This, however, is a labour-intensive process for large-scale studies...
  10. ncbi Tumor size and breast cancer detection: what might be the effect of a less sensitive screening tool than mammography?
    Stephen W Duffy
    Cancer Research UK Center for Epidemiology, Mathematics, and Statistics, Wolfson Institute of Preventive Medicine, London, United Kingdom
    Breast J 12:S91-5. 2006
    ..Our findings suggest that a less sensitive tool might be expected to confer a breast cancer mortality reduction about half of that observed with mammography...
  11. ncbi Some current issues in breast cancer screening
    Stephen W Duffy
    Cancer Research UK Centre for Epidemiology, Mathematics and Statistics, Wolfson Institute of Preventive Medicine, London EC1M 6BQ, UK
    J Med Screen 12:128-33. 2005
    ..This paper describes examples of approaches to the above issues, along with some important results...
  12. ncbi Some issues in screening for breast and other cancers
    Stephen W Duffy
    Cancer Research UK Centre for Epidemiology, Mathematics and Statistics, Wolfson Institute of Preventive Medicine, London
    J Med Screen 13:S28-34. 2006
    ..There are some issues in screening for cancer, especially breast cancer, which are worthy of further study...
  13. ncbi Overdiagnosis, sojourn time, and sensitivity in the Copenhagen mammography screening program
    Anne Helene Olsen
    Cancer Research UK, Department of Epidemiology, Mathematics, and Statistics, Wolfson Institute of Preventive Medicine, Charterhouse Square, London, United Kingdom
    Breast J 12:338-42. 2006
    ..A modest overdiagnosis was estimated for the Copenhagen screening program, deriving almost exclusively from the first screen. The CIs were very broad, however, and estimates from larger datasets are warranted...
  14. ncbi The relative contributions of screen-detected in situ and invasive breast carcinomas in reducing mortality from the disease
    S W Duffy
    Cancer Research UK Department of Epidemiology, Mathematics and Statistics, Wolfson Institute of Preventive Medicine, Queen Mary University of London, Charterhouse Square, London EC1M 6BQ, UK
    Eur J Cancer 39:1755-60. 2003
    ..Treatment decisions in DCIS, as in invasive carcinoma, should take full account of histopathological, clinical and radiological attributes of the tumour...
  15. ncbi The Swedish Two-County Trial of mammographic screening: cluster randomisation and end point evaluation
    S W Duffy
    Queen Mary University of London, London, UK
    Ann Oncol 14:1196-8. 2003
    ..The Swedish Two-County Trial has been criticised on the grounds of the cluster randomisation and alleged bias in classification of cause of death...
  16. ncbi What information should be given to women invited for mammographic screening for breast cancer?
    Stephen W Duffy
    Cancer Research UK Centre for Epidemiology, Mathematics and Statistics, London, UK
    Womens Health (Lond Engl) 2:829-33. 2006
    ..We suggest a few simple and clear points that should be made to the invited women, summarizing the positive and negative aspects without a mass of confusing statistics...
  17. pmc Commentary on 'what is the point: will screening mammography save my life?' by Keen and Keen
    Stephen W Duffy
    Cancer Research UK Centre for EMS, Wolfson Institute of Preventive Medicine, Barts and London School of Medicine and Dentistry, Charterhouse Square, London, EC1M 6BQ, UK
    BMC Med Inform Decis Mak 9:19. 2009
    ..Commentary on Keen and Keen 'What is the point: will screening mammography save my life?' BMC Medical Informatics and Decision Making, 2009...
  18. doi Modelling the likely effect of the increase of the upper age limit from 70 to 73 for breast screening in the UK National Programme
    S W Duffy
    Cancer Research UK Centre for Epidemiology, Mathematics and Statistics, Wolfson Institute of Preventive Medicine, Barts and the London School of Medicine and Dentistry, Queen Mary University of London, Charterhouse Square, London EC1M 6BQ, UK
    Stat Methods Med Res 19:547-55. 2010
    ..These results suggest that the expansion of the upper age limit will be cost-effective. They remain to be confirmed by evaluation of the age extension. They provide prior estimates that may inform the evaluation of the age extension...
  19. ncbi Quantifying the potential problem of overdiagnosis of ductal carcinoma in situ in breast cancer screening
    M F Yen
    Cancer Research UK Department of Epidemiology, Mathematics and Statistics, Wolfson Institute of Preventive Medicine, Queen Mary University of London, Charterhouse Square, London EC1M 6BQ, UK
    Eur J Cancer 39:1746-54. 2003
    ..There is an element of overdiagnosis of DCIS in breast cancer screening, but the phenomenon is small in both relative and absolute terms...
  20. doi Evaluation of mammographic surveillance services in women aged 40-49 years with a moderate family history of breast cancer: a single-arm cohort study
    S W Duffy
    Centre for Cancer Prevention, Wolfson Institute of Preventive Medicine, Barts and the London School of Medicine and Dentistry, Queen Mary, University of London, London, UK
    Health Technol Assess 17:vii-xiv, 1-95. 2013
    ..Up to now, this strategy has not been fully evaluated...
  21. pmc A case-control study of the impact of the East Anglian breast screening programme on breast cancer mortality
    P C Allgood
    Cancer Research UK Department of Epidemiology, Mathematics and Statistics, Wolfson Institute of Preventive Medicine, Charterhouse Square, London EC1M 6BQ, UK
    Br J Cancer 98:206-9. 2008
    ....
  22. ncbi Breast density and breast cancer risk factors in a high-risk population
    J Warwick
    Department of Mathematics, Statistics and Epidemiology, Cancer Research UK, London WC2A 3PX, UK
    Breast 12:10-6. 2003
    ....
  23. pmc Molecular subtyping of DCIS: heterogeneity of breast cancer reflected in pre-invasive disease
    S E Clark
    Centre for Tumour Biology, Institute of Cancer and CR UK Clinical Centre, Barts and the London School of Medicine and Dentistry, John Vane Science Centre, Charterhouse Square, London EC1M 6BQ, UK
    Br J Cancer 104:120-7. 2011
    ....
  24. ncbi Evaluation of service screening mammography in practice: the impact on breast cancer mortality
    R Gabe
    Wolfson Institute of Preventive Medicine, Cancer Research UK Centre for Epidemiology, Mathematics and Statistics, London, UK
    Ann Oncol 16:ii153-62. 2005
  25. ncbi Mammographic breast density by area of residence: possible evidence of higher density in urban areas
    N M Perry
    London Breast Institute, Princess Grace Hospital, 42 52 Nottingham Place, London, UK
    Curr Med Res Opin 24:365-8. 2008
    ..A comparison of mammographic breast densities of women living in London with those of women living in rural and suburban areas...
  26. ncbi A case-control study to estimate the impact of the Icelandic population-based mammography screening program on breast cancer death
    R Gabe
    Cancer Research UK, Centre for Epidemiology, Mathematics and Statistics, Wolfson Institute of Preventive Medicine, London, UK and Icelandic Cancer Society Krabbameinsfélag Islands, Reykjavik, Iceland
    Acta Radiol 48:948-55. 2007
    ..The Icelandic breast cancer screening program, initiated November 1987 in Reykjavik and covering the whole country from December 1989, comprises biennial invitation to mammography for women aged 40-69 years old...
  27. pmc What should the detection rates of cancers be in breast screening programmes?
    S W Duffy
    Cancer Research UK, Centre for Epidemiology, Mathematics and Statistics, Wolfson Institute of Preventive Medicine, Charterhouse Square, London EC1M 6BQ, UK
    Br J Cancer 92:597-600. 2005
    ..1 and 4.3 at prevalence screen and incidence screens, respectively; expected rates should be 6.9 and 4.8 and maximum rates of 9.6 and 5.5. These are consistent with observed detection rates in the UK programme...
  28. ncbi Audit of negative assessments in a breast-screening programme in women who later develop breast cancer-implications for survival
    P C Allgood
    QA Reference Centre for Cancer Screening for Eastern Region, Wolfson Institute of Preventive Medicine, Charterhouse Square, London EC1 M 6BQ, UK
    Breast 15:503-9. 2006
    ..Increased use of percutaneous biopsy in recent years should address the problem...
  29. ncbi Mammographic casting-type calcification associated with small screen-detected invasive breast cancers: is this a reliable prognostic indicator?
    C Peacock
    The South West London Breast Screening Service, The Duchess of Kent Unit, London, UK
    Clin Radiol 59:165-70; discussion 163-4. 2004
    ..The aim of the present study was to establish whether mammographic casting-type calcification associated with small screen-detected invasive breast cancers is a reliable prognostic indicator...
  30. pmc Explaining the difference in prognosis between screen-detected and symptomatic breast cancers
    P C Allgood
    CR UK Centre for Epidemiology, Mathematics and Statistics, Wolfson Institute for Preventive Medicine, Charterhouse Square, London WC1M 6BQ, UK
    Br J Cancer 104:1680-5. 2011
    ....
  31. ncbi A breast cancer prediction model incorporating familial and personal risk factors
    Jonathan Tyrer
    Department of Epidemiology, Mathematics and Statistics, Cancer Research UK
    Stat Med 23:1111-30. 2004
    ..This risk was further refined based on the woman's personal history. The model has been incorporated into a computer program that gives a personalised risk estimate...
  32. ncbi Time-dependent effects on survival in breast carcinoma: results of 20 years of follow-up from the Swedish Two-County Study
    Jane Warwick
    Department of Epidemiology, Mathematics, and Statistics, Cancer Research UK, Wolfson Institute of Preventive Medicine, London, UK
    Cancer 100:1331-6. 2004
    ..However, to the authors' knowledge, the effect of these factors in the longer term (>10 years after diagnosis) is not yet clear...
  33. ncbi Tamoxifen and breast density in women at increased risk of breast cancer
    Jack Cuzick
    Cancer Research UK, Department of Epidemiology, Mathematics and Statistics, Wolfson Institute of Preventive Medicine, Queen Mary College, University of London, London, UK
    J Natl Cancer Inst 96:621-8. 2004
    ..We investigated mammographic breast density in healthy women with an increased risk of breast cancer at baseline and during 54 months of tamoxifen treatment...
  34. doi A deterministic model for estimating the reduction in colorectal cancer incidence due to endoscopic surveillance
    Fay H Cafferty
    Cancer Research UK Centre for Epidemiology, Mathematics and Statistics, Wolfson Institute of Preventive Medicine, Queen Mary University of London, London, UK
    Stat Methods Med Res 18:163-82. 2009
    ..They indicate that polypectomy and follow-up surveillance can lead to large reductions in cancer incidence which may have been under-estimated in previous studies...
  35. ncbi Misclassification in a matched case-control study with variable matching ratio: application to a study of c-erbB-2 overexpression and breast cancer
    Stephen W Duffy
    Department of Epidemiology, Wolfson Institute of Preventive Medicine, Queen Mary University of London, Charterhouse Square, London EC1M 6BQ, UK
    Stat Med 22:2459-68. 2003
    ..An example is given from a study of risk factors for progression of benign breast disease to breast cancer, in which the risk factor is a biological marker measured with poor sensitivity...
  36. ncbi Findings at follow-up endoscopies in subjects with suspected colorectal abnormalities: effects of baseline findings and time to follow-up
    Fay H Cafferty
    Cancer Research UK Centre for Epidemiology, Mathematics and Statistics, Wolfson Institute of Preventive Medicine, Queen Mary University of London, London, England
    Cancer J 13:263-70. 2007
    ..The risk of various outcomes at the second examination is assessed according to findings at the first examination and the interval between examinations...
  37. ncbi Bayesian evaluation of breast cancer screening using data from two studies
    Jonathan P Myles
    Department of Mathematics, Statistics and Epidemiology, Cancer Research UK, London, UK
    Stat Med 22:1661-74. 2003
    ..The method is applied to the synthesis of two studies of mammographic screening in women with a family history of breast cancer, one in Manchester and one in Kopparberg, Sweden...
  38. ncbi Surrogate endpoints for cancer screening trials: general principles and an illustration using the UK Flexible Sigmoidoscopy Screening Trial
    Jack Cuzick
    Cancer Research UK Centre for Epidemiology, Mathematics and Statistics, Wolfson Institute of Preventive Medicine, Queen Mary University of London, London, UK
    J Med Screen 14:178-85. 2007
    ..Surrogate endpoints should not replace a long-term analysis based directly on mortality, but can provide reliable early indicators which can be useful both for monitoring ongoing screening programmes and for making policy decisions...
  39. ncbi Prospective estimation of rates of change in mammographic parenchymal patterns: influence of age and of hormone replacement therapy
    Jonathan P Myles
    Cancer Research UK, Department of Mathematics, Statistics and Epidemiology, Wolfson Institute of Preventitive Medicine, Charterhouse Square, London EC1M 6BQ, UK
    Breast 13:56-60. 2004
    ..The probability of non-dense patterns and the rate of change to non-dense patterns are reduced with HRT use. Errors of classification are relatively rare, but are dependent on the age of the subject...
  40. ncbi Development of a protocol for evaluation of mammographic surveillance services in women under 50 with a family history of breast cancer
    J Mackay
    North East Thames Regional Genetics Service, Institute of Child Health, London, UK
    J Epidemiol Biostat 6:365-9; discussion 371-5. 2001
    ..Incremental cost-effectiveness ratios of implementing the standardised mammography strategy compared with no screening will be presented in terms of the additional cost per cancer detected, per life saved and per life-year saved...
  41. ncbi The impact of organized mammography service screening on breast carcinoma mortality in seven Swedish counties
    Stephen W Duffy
    Department of Mathematics, Statistics and Epidemiology, Cancer Research UK, PO Box 123, Lincoln s Inn Fields, London WC2A 3PX, United Kingdom
    Cancer 95:458-69. 2002
    ..e., nonattenders) after the initiation of organized screening...
  42. doi Correcting for lead time and length bias in estimating the effect of screen detection on cancer survival
    Stephen W Duffy
    Cancer Research UK Centre for Epidemiology, Mathematics and Statistics, Wolfson Institute for Preventive Medicine, London, United Kingdom
    Am J Epidemiol 168:98-104. 2008
    ..Here they demonstrate these methods using a series of 25,962 breast cancer cases (1988-2004) from the West Midlands, United Kingdom...
  43. pmc A randomised trial of weekend and evening breast screening appointments
    J Offman
    Barts and the London School of Medicine and Dentistry, Queen Mary, University of London, London EC1M 6BQ, UK
    Br J Cancer 109:597-602. 2013
    ..There is a need to research interventions that improve access to and convenience of breast cancer screening services...
  44. pmc Early onset of breast cancer in a group of British black women
    R L Bowen
    Centre for Tumour Biology, Institute of Cancer and CR UK Clinical Centre, Barts and The London, Queen Mary s School of Medicine and Dentistry, John Vane Science Centre, Charterhouse Square, London EC1M 6BQ, UK
    Br J Cancer 98:277-81. 2008
    ..There were no disparities in socioeconomic status or treatment received. Our findings could have major implications for the biology of breast cancer and the detection and treatment of the disease in black women...
  45. doi Use of lung cancer risk models in planning research and service programs in CT screening for lung cancer
    Stephen W Duffy
    Cancer Research UK Centre for EMS, Wolfson Institute of Preventive Medicine, Barts and the London School of Medicine and Dentistry, Charterhouse Square, London EC1M 6BQ, UK
    Expert Rev Anticancer Ther 9:1467-72. 2009
    ....
  46. pmc Avoiding bias from aggregate measures of exposure
    Stephen W Duffy
    Cancer Research UK Centre for Epidemiology, Mathematics and Statistics, Wolfson Institute of Preventive Medicine, Charterhouse Square, London EC1M 6BQ, UK
    J Epidemiol Community Health 61:461-3. 2007
    ..To show how the individual level effect can be correctly estimated by excess relative risk models. METHODS: The problem and solution are demonstrated using data on prostate-specific antigen testing and prostate cancer incidence...
  47. doi Translation of research results to simple estimates of the likely effect of a lung cancer screening programme in the United Kingdom
    S W Duffy
    Centre for Cancer Prevention, Wolfson Institute of Preventive Medicine, Queen Mary University of London, Charterhouse Square, London EC1M 6BQ, UK
    Br J Cancer 110:1834-40. 2014
    ..The evidence base for low-dose CT screening for lung cancer pertains almost entirely to annual screening. The benefit of biennial screening is subject to additional uncertainty but the issue merits further empirical research. ..
  48. doi Strategy for power calculation for interactions: application to a trial of interventions to improve uptake of bowel cancer screening
    A R Brentnall
    Queen Mary University of London, Centre for Cancer Prevention, Wolfson Institute of Preventive Medicine, Barts and The London, Charterhouse Square, London EC1M 6BQ, UK
    Contemp Clin Trials 33:213-7. 2012
    ..A computer simulation experiment shows that the approach is more conservative than a likelihood-ratio calculation, and it appears sensible when compared with repeated application of a two-sample calculation at each quintile...
  49. doi Potential surrogate endpoints in cancer research--some considerations and examples
    S W Duffy
    Cancer Research UK Centre for EMS, Wolfson Institute of Preventive Medicine, Barts and the London School of Medicine and Dentistry, Queen Mary University of London, London, UK
    Pharm Stat 10:34-9. 2011
    ..Circumstances in which a surrogate endpoint may actually be preferred to the clinical endpoint are described. We provide pointers to the recent substantive literature on surrogates...
  50. ncbi A potentially useful distribution model for dietary intake data
    J P Myles
    Cancer Research UK Department of Epidemiology, Mathematics and Statistics, Wolfson Institute of Preventive Medicine, Charterhouse Square, EC1M 6BQ, UK
    Public Health Nutr 6:513-9. 2003
    ..Conventional mixed models for the analysis of diet diary data have introduced several simplifying assumptions, such as that of a single standard deviation for within-person day-to-day variation which is common to all individuals...
  51. pmc Lymph node status and breast cancer-related lymphedema
    Anand D Purushotham
    King s College London, London, United Kingdom
    Ann Surg 246:42-5. 2007
    ..This study examines the association between nodal positivity and risk of developing breast cancer-related lymphedema (BCRL) in patients who underwent axillary lymph node dissection (ALND)...
  52. pmc Absolute numbers of lives saved and overdiagnosis in breast cancer screening, from a randomized trial and from the Breast Screening Programme in England
    Stephen W Duffy
    CR UK Centre for Epidemiology, Statistics and Mathematics, Wolfson Institute for Preventive Medicine, Barts and the London School of Medicine and Dentistry, Queen Mary University of London, Charterhouse Square, London EC1M 6BQ, UK
    J Med Screen 17:25-30. 2010
    ..To estimate the absolute numbers of breast cancer deaths prevented and the absolute numbers of tumours overdiagnosed in mammographic screening for breast cancer at ages 50-69 years...
  53. doi Once-only flexible sigmoidoscopy screening in prevention of colorectal cancer: a multicentre randomised controlled trial
    Wendy S Atkin
    Department of Surgery and Cancer, Imperial College London, London, UK
    Lancet 375:1624-33. 2010
    ..We tested the hypothesis that only one flexible sigmoidoscopy screening between 55 and 64 years of age can substantially reduce colorectal cancer incidence and mortality...
  54. ncbi Update on effects of screening mammography
    Laszlo Tabar
    Lancet 360:337; author reply 339-40. 2002
  55. ncbi Mammographic parenchymal patterns and self-reported soy intake in Singapore Chinese women
    Rupert W Jakes
    National Medical Research Council Clinical Trials and Epidemiology Research Unit, Singapore 169039
    Cancer Epidemiol Biomarkers Prev 11:608-13. 2002
    ..20-0.98). The association between high soy intake and a reduced risk of mammographic parenchymal patterns that are associated with high breast cancer risk may have important implications in breast cancer prevention...
  56. pmc Are breast cancer screening programmes increasing rates of mastectomy? Observational study
    Eugenio Paci
    Unit of Epidemiology, Centre for the Study and Prevention of Cancer CSPO, Via di S Salvi 12, 50135 Florence, Italy
    BMJ 325:418. 2002
  57. ncbi Mammographic tumor features can predict long-term outcomes reliably in women with 1-14-mm invasive breast carcinoma
    Laszlo Tabar
    Mammography Department, Central Hospital, Falun, Sweden
    Cancer 101:1745-59. 2004
    ..The radiologic images of 1-14-mm invasive breast carcinomas can be classified into 5 separate categories. The use of these mammographic indicators to predict patient outcome has important prognostic and therapeutic implications...
  58. ncbi Prognosis of small hepatocellular carcinoma treated by percutaneous ethanol injection and transcatheter arterial chemoembolization
    Chao Sheng Liao
    Department of Internal Medicine, Shin Kong Wu Ho Su Memorial Hospital, No 95, Wen Chang Road, Taipei, Taiwan, Republic of China
    J Clin Epidemiol 55:1095-104. 2002
    ..Our results suggest the optimal frequency of clinical surveillance of small HCC cases after treatment should take account of increased hazard rate with time and the roles of pretreatment clinico-pathologic variables...
  59. ncbi The mammographic screening trials: commentary on the recent work by Olsen and Gøtzsche
    Stephen W Duffy
    CA Cancer J Clin 52:68-71. 2002
  60. ncbi The controversy over breast cancer screening
    Stephen W Duffy
    Hosp Med 63:708-9. 2002
  61. ncbi Mammography service screening and mortality in breast cancer patients: 20-year follow-up before and after introduction of screening
    Laszlo Tabar
    Department of Mammography, Central Hospital, Falun, Sweden
    Lancet 361:1405-10. 2003
    ..We aimed to assess the long-term effect of mammographic screening on death from breast cancer, taking into account potential biases from self-selection, changes in breast cancer incidence, and classification of cause of death...
  62. doi Single reading with computer-aided detection for screening mammography
    Fiona J Gilbert
    Aberdeen Biomedical Imaging Centre, University of Aberdeen, Aberdeen, Scotland, United Kingdom
    N Engl J Med 359:1675-84. 2008
    ..We conducted a trial to determine whether the performance of a single reader using a computer-aided detection system would match the performance achieved by two readers...
  63. ncbi Single reading with computer-aided detection and double reading of screening mammograms in the United Kingdom National Breast Screening Program
    Fiona J Gilbert
    Department of Radiology, University of Aberdeen, Lilian Sutton Bldg, Foresterhill, Aberdeen, Scotland
    Radiology 241:47-53. 2006
    ..To retrospectively determine if the use of a computer-aided detection (CAD) system can improve the performance of single reading of screening mammograms to match that of double reading in the United Kingdom...
  64. ncbi Defining high-risk individuals in a population-based molecular-epidemiological study of lung cancer
    Adrian Cassidy
    Roy Castle Lung Cancer Research Programme, University of Liverpool Cancer Research Centre, University of Liverpool, Liverpool L3 9TA, UK
    Int J Oncol 28:1295-301. 2006
    ..The development of a molecular-epidemiological model will inform the development of effective surveillance, early detection and chemoprevention strategies...
  65. ncbi Breast cancer in limited-resource countries: early detection and access to care
    Robert A Smith
    American Cancer Society, Atlanta, Georgia 30329, USA
    Breast J 12:S16-26. 2006
    ..Ideally, for complete evaluation, such projects require notification of deaths among breast cancer cases and staging of diagnosed tumors...
  66. ncbi Re: Efficacy of breast cancer screening in the community according to risk level
    Stephen W Duffy
    J Natl Cancer Inst 97:1703; author reply 1703-4. 2005
  67. ncbi The randomized trials of breast cancer screening: what have we learned?
    Robert A Smith
    American Cancer Society, 1599 Clifton Road, NE, Atlanta, GA 30329, USA
    Radiol Clin North Am 42:793-806, v. 2004
    ..The trials of mammographic screening provide conclusive evidence that the policy of offering screening is associated with a significant and substantial reduction in breast cancer mortality...
  68. ncbi Progression rates of colorectal cancer by Dukes' stage in a high-risk group: analysis of selective colorectal cancer screening
    Jau Min Wong
    Department of Internal Medicine, College of Public Health, National Taiwan University Hospital, No 19 Hsuchow Road, Taipei 100, Taiwan
    Cancer J 10:160-9. 2004
    ..The progression rates of colorectal cancer by Dukes' stage in a high-risk group were estimated and applied to evaluate the efficacy of different screening regimens...
  69. ncbi Mammographic screening: a key factor in the control of breast cancer
    Laszlo Tabar
    Department of Mammography, Central Hospital, Fallun, Sweden
    Cancer J 9:15-27. 2003
  70. ncbi The Gothenburg Breast Screening Trial
    Nils Bjurstam
    Department of Radiology, Center for Breast Imaging, University Hospital of North Norway, Tromsø, Norway
    Cancer 97:2387-96. 2003
    ..Although there is evidence for a reduction in breast carcinoma mortality with mammographic screening, some doubts have been expressed, and there is still uncertainty regarding the age specific effects...
  71. ncbi Cancer screening in Asia
    Stephen W Duffy
    J Med Screen 13:S1. 2006
  72. ncbi Commentary: axillary dissection in breast cancer updated
    Stephen W Duffy
    Breast 14:83-4. 2005
  73. ncbi Lung cancer risk prediction: a tool for early detection
    Adrian Cassidy
    Roy Castle Lung Cancer Research Programme, University of Liverpool Cancer Research Centre, Liverpool, United Kingdom
    Int J Cancer 120:1-6. 2007
    ..Validation is essential to establish the predictive effect and for ongoing monitoring of the model's continued relevance...
  74. ncbi Ultrasound screening and risk factors for death from hepatocellular carcinoma in a high risk group in Taiwan
    Tony Hsiu Hsi Chen
    Institute of Preventive Medicine, College of Public Health, National Taiwan University, Taipei, Taiwan
    Int J Cancer 98:257-61. 2002
    ..A randomized controlled trial would yield definitive evidence. Within the protocol of such a trial, a shorter interscreening interval for patients with liver cirrhosis is suggested...