Research Topics
| S W DuffySummaryAffiliation: Cancer Research UK Country: UK Publications
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Detail Information
Publications
Complexities in the estimation of overdiagnosis in breast cancer screeningS W Duffy
Cancer Research UK Centre for Epidemiology Mathematics and Statistics, Wolfson Institute of Preventive Medicine, Charterhouse Square, London EC1 M 6BQ, UK
Br J Cancer 99:1176-8. 2008..We illustrate this using an example of analysis of breast cancer incidence data from Sweden...
Screening for breast cancerStephen W Duffy
Cancer Research UK, Department of Epidemiology, Mathematics and Statistics, Wolfson Institute of Preventive Medicine, Queen Mary University of London, London EC1M 6BQ, UK
Surg Oncol Clin N Am 14:671-97. 2005....
Overdiagnosis and overtreatment of breast cancer: estimates of overdiagnosis from two trials of mammographic screening for breast cancerStephen W Duffy
Cancer Research UK Department of Epidemiology, Mathematics and Statistics, Wolfson Institute of Preventive Medicine, Queen Mary College, University of London, London, UK
Breast Cancer Res 7:258-65. 2005..Our results suggest that overdiagnosis in mammography screening is a minor phenomenon, but further studies with very large numbers are required for more precise estimation...
Overdiagnosis and overtreatment of breast cancer: overdiagnosis and overtreatment in service screeningEugenio Paci
Unit of Clinical and Descriptive Epidemiology, CSPO, Research Institute of the Tuscany, Via di SanSalvi, Florence, Italy
Breast Cancer Res 7:266-70. 2005..The overtreatment issue is discussed in terms of appropriateness of effective treatment considering the question of chemotherapy in very early stages and the use of breast conserving surgery...
Variable size computer-aided detection prompts and mammography film reader decisionsFiona J Gilbert
Division of Applied Medicine, School of Medicine and Dentistry, University of Aberdeen, Lilian Sutton Building, Foresterhill, Aberdeen AB25 2ZD, UK
Breast Cancer Res 10:R72. 2008....
Imputation of a true endpoint from a surrogate: application to a cluster randomized controlled trial with partial information on the true endpointRichard M Nixon
MRC Biostatistics Unit, Institute of Public Health, Robinson Way, Cambridge, CB2 2SR, UK
BMC Med Res Methodol 3:17. 2003..Data are only available for the true end point on a sub set of the practices, but there are surrogate data for almost all of the audited practices and for most of the remaining practices...
The relative contributions of screen-detected in situ and invasive breast carcinomas in reducing mortality from the diseaseS W Duffy
Cancer Research UK Department of Epidemiology, Mathematics and Statistics, Wolfson Institute of Preventive Medicine, Queen Mary University of London, Charterhouse Square, London EC1M 6BQ, UK
Eur J Cancer 39:1755-60. 2003..Treatment decisions in DCIS, as in invasive carcinoma, should take full account of histopathological, clinical and radiological attributes of the tumour...
Tumor size and breast cancer detection: what might be the effect of a less sensitive screening tool than mammography?Stephen W Duffy
Cancer Research UK Center for Epidemiology, Mathematics, and Statistics, Wolfson Institute of Preventive Medicine, London, United Kingdom
Breast J 12:S91-5. 2006..Our findings suggest that a less sensitive tool might be expected to confer a breast cancer mortality reduction about half of that observed with mammography...
Interaction of dense breast patterns with other breast cancer risk factors in a case-control studyS W Duffy
Cancer Research UK, Department of Epidemiology, Mathematics and Statistics, Wolfson Institute of Preventive Medicine, Charterhouse Square, London EC1M 6BQ, UK
Br J Cancer 91:233-6. 2004..The results are consistent with dense breast patterns as a marker for hormonal modification of breast cancer risk...
A simple model for potential use with a misclassified binary outcome in epidemiologyS W Duffy
Cancer Research UK Department of Epidemiology, Mathematics and Statistics, Wolfson Institute of Preventive Medicine, Queen Mary University of London, UK
J Epidemiol Community Health 58:712-7. 2004..A method of correction of risk estimates for misclassification of a binary disease outcome is developed here...
Some issues in screening for breast and other cancersStephen W Duffy
Cancer Research UK Centre for Epidemiology, Mathematics and Statistics, Wolfson Institute of Preventive Medicine, London
J Med Screen 13:S28-34. 2006..There are some issues in screening for cancer, especially breast cancer, which are worthy of further study...
Overdiagnosis, sojourn time, and sensitivity in the Copenhagen mammography screening programAnne Helene Olsen
Cancer Research UK, Department of Epidemiology, Mathematics, and Statistics, Wolfson Institute of Preventive Medicine, Charterhouse Square, London, United Kingdom
Breast J 12:338-42. 2006..A modest overdiagnosis was estimated for the Copenhagen screening program, deriving almost exclusively from the first screen. The CIs were very broad, however, and estimates from larger datasets are warranted...
Some current issues in breast cancer screeningStephen W Duffy
Cancer Research UK Centre for Epidemiology, Mathematics and Statistics, Wolfson Institute of Preventive Medicine, London EC1M 6BQ, UK
J Med Screen 12:128-33. 2005..This paper describes examples of approaches to the above issues, along with some important results...
The Swedish Two-County Trial of mammographic screening: cluster randomisation and end point evaluationS W Duffy
Queen Mary University of London, London, UK
Ann Oncol 14:1196-8. 2003..The Swedish Two-County Trial has been criticised on the grounds of the cluster randomisation and alleged bias in classification of cause of death...
What information should be given to women invited for mammographic screening for breast cancer?Stephen W Duffy
Cancer Research UK Centre for Epidemiology, Mathematics and Statistics, London, UK
Womens Health (Lond Engl) 2:829-33. 2006..We suggest a few simple and clear points that should be made to the invited women, summarizing the positive and negative aspects without a mass of confusing statistics...
Visually assessed breast density, breast cancer risk and the importance of the craniocaudal viewStephen W Duffy
Department of Epidemiology, Mathematics and Statistics, Wolfson Institute of Preventive Medicine, Charterhouse Square, London EC1M 6BQ, UK
Breast Cancer Res 10:R64. 2008..A particularly strong association with risk has been observed when density is measured using interactive threshold software. This, however, is a labour-intensive process for large-scale studies...
Modelling the likely effect of the increase of the upper age limit from 70 to 73 for breast screening in the UK National ProgrammeS W Duffy
Cancer Research UK Centre for Epidemiology, Mathematics and Statistics, Wolfson Institute of Preventive Medicine, Barts and the London School of Medicine and Dentistry, Queen Mary University of London, Charterhouse Square, London EC1M 6BQ, UK
Stat Methods Med Res 19:547-55. 2010..These results suggest that the expansion of the upper age limit will be cost-effective. They remain to be confirmed by evaluation of the age extension. They provide prior estimates that may inform the evaluation of the age extension...
Commentary on 'what is the point: will screening mammography save my life?' by Keen and KeenStephen W Duffy
Cancer Research UK Centre for EMS, Wolfson Institute of Preventive Medicine, Barts and London School of Medicine and Dentistry, Charterhouse Square, London, EC1M 6BQ, UK
BMC Med Inform Decis Mak 9:19. 2009..Commentary on Keen and Keen 'What is the point: will screening mammography save my life?' BMC Medical Informatics and Decision Making, 2009...
A case-control study of the impact of the East Anglian breast screening programme on breast cancer mortalityP C Allgood
Cancer Research UK Department of Epidemiology, Mathematics and Statistics, Wolfson Institute of Preventive Medicine, Charterhouse Square, London EC1M 6BQ, UK
Br J Cancer 98:206-9. 2008....
Quantifying the potential problem of overdiagnosis of ductal carcinoma in situ in breast cancer screeningM-F Yen
Cancer Research UK Department of Epidemiology, Mathematics and Statistics, Wolfson Institute of Preventive Medicine, Queen Mary University of London, Charterhouse Square, London EC1M 6BQ, UK
Eur J Cancer 39:1746-54. 2003..There is an element of overdiagnosis of DCIS in breast cancer screening, but the phenomenon is small in both relative and absolute terms...
Breast density and breast cancer risk factors in a high-risk populationJ Warwick
Department of Mathematics, Statistics and Epidemiology, Cancer Research UK, London WC2A 3PX, UK
Breast 12:10-6. 2003....
Evaluation of service screening mammography in practice: the impact on breast cancer mortalityR Gabe
Wolfson Institute of Preventive Medicine, Cancer Research UK Centre for Epidemiology, Mathematics and Statistics, London, UK
Ann Oncol 16:ii153-62. 2005
Molecular subtyping of DCIS: heterogeneity of breast cancer reflected in pre-invasive diseaseS E Clark
Centre for Tumour Biology, Institute of Cancer and CR UK Clinical Centre, Barts and the London School of Medicine and Dentistry, John Vane Science Centre, Charterhouse Square, London EC1M 6BQ, UK
Br J Cancer 104:120-7. 2011....
Mammographic breast density by area of residence: possible evidence of higher density in urban areasN M Perry
London Breast Institute, Princess Grace Hospital, 42 52 Nottingham Place, London, UK
Curr Med Res Opin 24:365-8. 2008..A comparison of mammographic breast densities of women living in London with those of women living in rural and suburban areas...
Explaining the difference in prognosis between screen-detected and symptomatic breast cancersP C Allgood
CR UK Centre for Epidemiology, Mathematics and Statistics, Wolfson Institute for Preventive Medicine, Charterhouse Square, London WC1M 6BQ, UK
Br J Cancer 104:1680-5. 2011....
Audit of negative assessments in a breast-screening programme in women who later develop breast cancer-implications for survivalP C Allgood
QA Reference Centre for Cancer Screening for Eastern Region, Wolfson Institute of Preventive Medicine, Charterhouse Square, London EC1 M 6BQ, UK
Breast 15:503-9. 2006..Increased use of percutaneous biopsy in recent years should address the problem...
A case-control study to estimate the impact of the Icelandic population-based mammography screening program on breast cancer deathR Gabe
Cancer Research UK, Centre for Epidemiology, Mathematics and Statistics, Wolfson Institute of Preventive Medicine, London, UK and Icelandic Cancer Society Krabbameinsfélag Islands, Reykjavik, Iceland
Acta Radiol 48:948-55. 2007..The Icelandic breast cancer screening program, initiated November 1987 in Reykjavik and covering the whole country from December 1989, comprises biennial invitation to mammography for women aged 40-69 years old...
What should the detection rates of cancers be in breast screening programmes?S W Duffy
Cancer Research UK, Centre for Epidemiology, Mathematics and Statistics, Wolfson Institute of Preventive Medicine, Charterhouse Square, London EC1M 6BQ, UK
Br J Cancer 92:597-600. 2005..1 and 4.3 at prevalence screen and incidence screens, respectively; expected rates should be 6.9 and 4.8 and maximum rates of 9.6 and 5.5. These are consistent with observed detection rates in the UK programme...
Mammographic casting-type calcification associated with small screen-detected invasive breast cancers: is this a reliable prognostic indicator?C Peacock
The South West London Breast Screening Service, The Duchess of Kent Unit, London, UK
Clin Radiol 59:165-70; discussion 163-4. 2004..The aim of the present study was to establish whether mammographic casting-type calcification associated with small screen-detected invasive breast cancers is a reliable prognostic indicator...
Bayesian evaluation of breast cancer screening using data from two studiesJonathan P Myles
Department of Mathematics, Statistics and Epidemiology, Cancer Research UK, London, UK
Stat Med 22:1661-74. 2003..The method is applied to the synthesis of two studies of mammographic screening in women with a family history of breast cancer, one in Manchester and one in Kopparberg, Sweden...
Surrogate endpoints for cancer screening trials: general principles and an illustration using the UK Flexible Sigmoidoscopy Screening TrialJack Cuzick
Cancer Research UK Centre for Epidemiology, Mathematics and Statistics, Wolfson Institute of Preventive Medicine, Queen Mary University of London, London, UK
J Med Screen 14:178-85. 2007..Surrogate endpoints should not replace a long-term analysis based directly on mortality, but can provide reliable early indicators which can be useful both for monitoring ongoing screening programmes and for making policy decisions...
Prospective estimation of rates of change in mammographic parenchymal patterns: influence of age and of hormone replacement therapyJonathan P Myles
Cancer Research UK, Department of Mathematics, Statistics and Epidemiology, Wolfson Institute of Preventitive Medicine, Charterhouse Square, London EC1M 6BQ, UK
Breast 13:56-60. 2004..The probability of non-dense patterns and the rate of change to non-dense patterns are reduced with HRT use. Errors of classification are relatively rare, but are dependent on the age of the subject...
Time-dependent effects on survival in breast carcinoma: results of 20 years of follow-up from the Swedish Two-County StudyJane Warwick
Department of Epidemiology, Mathematics, and Statistics, Cancer Research UK, Wolfson Institute of Preventive Medicine, London, UK
Cancer 100:1331-6. 2004..However, to the authors' knowledge, the effect of these factors in the longer term (>10 years after diagnosis) is not yet clear...
A deterministic model for estimating the reduction in colorectal cancer incidence due to endoscopic surveillanceFay H Cafferty
Cancer Research UK Centre for Epidemiology, Mathematics and Statistics, Wolfson Institute of Preventive Medicine, Queen Mary University of London, London, UK
Stat Methods Med Res 18:163-82. 2009..They indicate that polypectomy and follow-up surveillance can lead to large reductions in cancer incidence which may have been under-estimated in previous studies...
A breast cancer prediction model incorporating familial and personal risk factorsJonathan Tyrer
Department of Epidemiology, Mathematics and Statistics, Cancer Research UK
Stat Med 23:1111-30. 2004..This risk was further refined based on the woman's personal history. The model has been incorporated into a computer program that gives a personalised risk estimate...
Findings at follow-up endoscopies in subjects with suspected colorectal abnormalities: effects of baseline findings and time to follow-upFay H Cafferty
Cancer Research UK Centre for Epidemiology, Mathematics and Statistics, Wolfson Institute of Preventive Medicine, Queen Mary University of London, London, England
Cancer J 13:263-70. 2007..The risk of various outcomes at the second examination is assessed according to findings at the first examination and the interval between examinations...
Tamoxifen and breast density in women at increased risk of breast cancerJack Cuzick
Cancer Research UK, Department of Epidemiology, Mathematics and Statistics, Wolfson Institute of Preventive Medicine, Queen Mary College, University of London, London, UK
J Natl Cancer Inst 96:621-8. 2004..We investigated mammographic breast density in healthy women with an increased risk of breast cancer at baseline and during 54 months of tamoxifen treatment...
Misclassification in a matched case-control study with variable matching ratio: application to a study of c-erbB-2 overexpression and breast cancerStephen W Duffy
Department of Epidemiology, Wolfson Institute of Preventive Medicine, Queen Mary University of London, Charterhouse Square, London EC1M 6BQ, UK
Stat Med 22:2459-68. 2003..An example is given from a study of risk factors for progression of benign breast disease to breast cancer, in which the risk factor is a biological marker measured with poor sensitivity...
Development of a protocol for evaluation of mammographic surveillance services in women under 50 with a family history of breast cancerJ Mackay
North East Thames Regional Genetics Service, Institute of Child Health, London, UK
J Epidemiol Biostat 6:365-9; discussion 371-5. 2001..Incremental cost-effectiveness ratios of implementing the standardised mammography strategy compared with no screening will be presented in terms of the additional cost per cancer detected, per life saved and per life-year saved...
The impact of organized mammography service screening on breast carcinoma mortality in seven Swedish countiesStephen W Duffy
Department of Mathematics, Statistics and Epidemiology, Cancer Research UK, PO Box 123, Lincoln s Inn Fields, London WC2A 3PX, United Kingdom
Cancer 95:458-69. 2002..e., nonattenders) after the initiation of organized screening...
Correcting for lead time and length bias in estimating the effect of screen detection on cancer survivalStephen W Duffy
Cancer Research UK Centre for Epidemiology, Mathematics and Statistics, Wolfson Institute for Preventive Medicine, London, United Kingdom
Am J Epidemiol 168:98-104. 2008..Here they demonstrate these methods using a series of 25,962 breast cancer cases (1988-2004) from the West Midlands, United Kingdom...
Evaluation of mammographic surveillance services in women aged 40-49 years with a moderate family history of breast cancer: a single-arm cohort studyS W Duffy
Centre for Cancer Prevention, Wolfson Institute of Preventive Medicine, Barts and the London School of Medicine and Dentistry, Queen Mary, University of London, London, UK
Health Technol Assess 17:vii-xiv, 1-95. 2013..Up to now, this strategy has not been fully evaluated...
Early onset of breast cancer in a group of British black womenR L Bowen
Centre for Tumour Biology, Institute of Cancer and CR UK Clinical Centre, Barts and The London, Queen Mary s School of Medicine and Dentistry, John Vane Science Centre, Charterhouse Square, London EC1M 6BQ, UK
Br J Cancer 98:277-81. 2008..There were no disparities in socioeconomic status or treatment received. Our findings could have major implications for the biology of breast cancer and the detection and treatment of the disease in black women...
Use of lung cancer risk models in planning research and service programs in CT screening for lung cancerStephen W Duffy
Cancer Research UK Centre for EMS, Wolfson Institute of Preventive Medicine, Barts and the London School of Medicine and Dentistry, Charterhouse Square, London EC1M 6BQ, UK
Expert Rev Anticancer Ther 9:1467-72. 2009....
Avoiding bias from aggregate measures of exposureStephen W Duffy
Cancer Research UK Centre for Epidemiology, Mathematics and Statistics, Wolfson Institute of Preventive Medicine, Charterhouse Square, London EC1M 6BQ, UK
J Epidemiol Community Health 61:461-3. 2007..To show how the individual level effect can be correctly estimated by excess relative risk models. METHODS: The problem and solution are demonstrated using data on prostate-specific antigen testing and prostate cancer incidence...
Strategy for power calculation for interactions: application to a trial of interventions to improve uptake of bowel cancer screeningA R Brentnall
Queen Mary University of London, Centre for Cancer Prevention, Wolfson Institute of Preventive Medicine, Barts and The London, Charterhouse Square, London EC1M 6BQ, UK
Contemp Clin Trials 33:213-7. 2012..A computer simulation experiment shows that the approach is more conservative than a likelihood-ratio calculation, and it appears sensible when compared with repeated application of a two-sample calculation at each quintile...
A potentially useful distribution model for dietary intake dataJ P Myles
Cancer Research UK Department of Epidemiology, Mathematics and Statistics, Wolfson Institute of Preventive Medicine, Charterhouse Square, EC1M 6BQ, UK
Public Health Nutr 6:513-9. 2003..Conventional mixed models for the analysis of diet diary data have introduced several simplifying assumptions, such as that of a single standard deviation for within-person day-to-day variation which is common to all individuals...
Potential surrogate endpoints in cancer research--some considerations and examplesS W Duffy
Cancer Research UK Centre for EMS, Wolfson Institute of Preventive Medicine, Barts and the London School of Medicine and Dentistry, Queen Mary University of London, London, UK
Pharm Stat 10:34-9. 2011..Circumstances in which a surrogate endpoint may actually be preferred to the clinical endpoint are described. We provide pointers to the recent substantive literature on surrogates...
Lymph node status and breast cancer-related lymphedemaAnand D Purushotham
King s College London, London, United Kingdom
Ann Surg 246:42-5. 2007..This study examines the association between nodal positivity and risk of developing breast cancer-related lymphedema (BCRL) in patients who underwent axillary lymph node dissection (ALND)...
Absolute numbers of lives saved and overdiagnosis in breast cancer screening, from a randomized trial and from the Breast Screening Programme in EnglandStephen W Duffy
CR UK Centre for Epidemiology, Statistics and Mathematics, Wolfson Institute for Preventive Medicine, Barts and the London School of Medicine and Dentistry, Queen Mary University of London, Charterhouse Square, London EC1M 6BQ, UK
J Med Screen 17:25-30. 2010..To estimate the absolute numbers of breast cancer deaths prevented and the absolute numbers of tumours overdiagnosed in mammographic screening for breast cancer at ages 50-69 years...
Once-only flexible sigmoidoscopy screening in prevention of colorectal cancer: a multicentre randomised controlled trialWendy S Atkin
Department of Surgery and Cancer, Imperial College London, London, UK
Lancet 375:1624-33. 2010..We tested the hypothesis that only one flexible sigmoidoscopy screening between 55 and 64 years of age can substantially reduce colorectal cancer incidence and mortality...
Are breast cancer screening programmes increasing rates of mastectomy? Observational studyEugenio Paci
Unit of Epidemiology, Centre for the Study and Prevention of Cancer CSPO, Via di S Salvi 12, 50135 Florence, Italy
BMJ 325:418. 2002
Single reading with computer-aided detection for screening mammographyFiona J Gilbert
Aberdeen Biomedical Imaging Centre, University of Aberdeen, Aberdeen, Scotland, United Kingdom
N Engl J Med 359:1675-84. 2008..We conducted a trial to determine whether the performance of a single reader using a computer-aided detection system would match the performance achieved by two readers...
Update on effects of screening mammographyLaszlo Tabar
Lancet 360:337; author reply 339-40. 2002
Breast cancer in limited-resource countries: early detection and access to careRobert A Smith
American Cancer Society, Atlanta, Georgia 30329, USA
Breast J 12:S16-26. 2006..Ideally, for complete evaluation, such projects require notification of deaths among breast cancer cases and staging of diagnosed tumors...
The mammographic screening trials: commentary on the recent work by Olsen and GøtzscheStephen W Duffy
CA Cancer J Clin 52:68-71. 2002
Mammographic parenchymal patterns and self-reported soy intake in Singapore Chinese womenRupert W Jakes
National Medical Research Council Clinical Trials and Epidemiology Research Unit, Singapore 169039
Cancer Epidemiol Biomarkers Prev 11:608-13. 2002..20-0.98). The association between high soy intake and a reduced risk of mammographic parenchymal patterns that are associated with high breast cancer risk may have important implications in breast cancer prevention...
Re: Efficacy of breast cancer screening in the community according to risk levelStephen W Duffy
J Natl Cancer Inst 97:1703; author reply 1703-4. 2005
Prognosis of small hepatocellular carcinoma treated by percutaneous ethanol injection and transcatheter arterial chemoembolizationChao-Sheng Liao
Department of Internal Medicine, Shin Kong Wu Ho-Su Memorial Hospital, No. 95, Wen Chang Road, Taipei, Taiwan, Republic of China
J Clin Epidemiol 55:1095-104. 2002..Our results suggest the optimal frequency of clinical surveillance of small HCC cases after treatment should take account of increased hazard rate with time and the roles of pretreatment clinico-pathologic variables...
Single reading with computer-aided detection and double reading of screening mammograms in the United Kingdom National Breast Screening ProgramFiona J Gilbert
Department of Radiology, University of Aberdeen, Lilian Sutton Bldg, Foresterhill, Aberdeen, Scotland
Radiology 241:47-53. 2006..To retrospectively determine if the use of a computer-aided detection (CAD) system can improve the performance of single reading of screening mammograms to match that of double reading in the United Kingdom...
Cancer screening in AsiaStephen W Duffy
J Med Screen 13:S1. 2006
The randomized trials of breast cancer screening: what have we learned?Robert A Smith
American Cancer Society, 1599 Clifton Road, NE, Atlanta, GA 30329, USA
Radiol Clin North Am 42:793-806, v. 2004..The trials of mammographic screening provide conclusive evidence that the policy of offering screening is associated with a significant and substantial reduction in breast cancer mortality...
Progression rates of colorectal cancer by Dukes' stage in a high-risk group: analysis of selective colorectal cancer screeningJau-Min Wong
Department of Internal Medicine, College of Public Health, National Taiwan University Hospital, No. 19 Hsuchow Road, Taipei 100, Taiwan
Cancer J 10:160-9. 2004....
Mammographic screening: a key factor in the control of breast cancerLaszlo Tabar
Department of Mammography, Central Hospital, Fallun, Sweden
Cancer J 9:15-27. 2003
The Gothenburg Breast Screening TrialNils Bjurstam
Department of Radiology, Center for Breast Imaging, University Hospital of North Norway, Tromsø, Norway
Cancer 97:2387-96. 2003..Although there is evidence for a reduction in breast carcinoma mortality with mammographic screening, some doubts have been expressed, and there is still uncertainty regarding the age specific effects...
Mammography service screening and mortality in breast cancer patients: 20-year follow-up before and after introduction of screeningLaszlo Tabar
Department of Mammography, Central Hospital, Falun, Sweden
Lancet 361:1405-10. 2003....
Defining high-risk individuals in a population-based molecular-epidemiological study of lung cancerAdrian Cassidy
Roy Castle Lung Cancer Research Programme, University of Liverpool Cancer Research Centre, University of Liverpool, Liverpool L3 9TA, UK
Int J Oncol 28:1295-301. 2006..The development of a molecular-epidemiological model will inform the development of effective surveillance, early detection and chemoprevention strategies...
The controversy over breast cancer screeningStephen W Duffy
Hosp Med 63:708-9. 2002
Mammographic tumor features can predict long-term outcomes reliably in women with 1-14-mm invasive breast carcinomaLaszlo Tabar
Mammography Department, Central Hospital, Falun, Sweden
Cancer 101:1745-59. 2004..Due to their already excellent survival, adjuvant therapeutic regimens are unlikely to offer further benefit for these patients...
Commentary: axillary dissection in breast cancer updatedStephen W Duffy
Breast 14:83-4. 2005
Lung cancer risk prediction: a tool for early detectionAdrian Cassidy
Roy Castle Lung Cancer Research Programme, University of Liverpool Cancer Research Centre, Liverpool, United Kingdom
Int J Cancer 120:1-6. 2007..Validation is essential to establish the predictive effect and for ongoing monitoring of the model's continued relevance...
Ultrasound screening and risk factors for death from hepatocellular carcinoma in a high risk group in TaiwanTony Hsiu-Hsi Chen
Institute of Preventive Medicine, College of Public Health, National Taiwan University, Taipei, Taiwan
Int J Cancer 98:257-61. 2002..A randomized controlled trial would yield definitive evidence. Within the protocol of such a trial, a shorter interscreening interval for patients with liver cirrhosis is suggested...
