H Raza Ali

Summary

Affiliation: Cancer Research UK
Country: UK

Publications

  1. pmc Astronomical algorithms for automated analysis of tissue protein expression in breast cancer
    H R Ali
    Department of Oncology, University of Cambridge, Cambridge CB1 9RN, UK
    Br J Cancer 108:602-12. 2013
  2. pmc Aurora kinase A outperforms Ki67 as a prognostic marker in ER-positive breast cancer
    H R Ali
    Department of Oncology, University of Cambridge, Cambridge CB1 9RN, UK
    Br J Cancer 106:1798-806. 2012
  3. doi A Ki67/BCL2 index based on immunohistochemistry is highly prognostic in ER-positive breast cancer
    H Raza Ali
    Department of Oncology, University of Cambridge, Cambridge, CB1 9RN, UK
    J Pathol 226:97-107. 2012
  4. pmc Cancer stem cell markers in breast cancer: pathological, clinical and prognostic significance
    H Raza Ali
    Department of Oncology, University of Cambridge, Cambridge CB1 9RN, UK
    Breast Cancer Res 13:R118. 2011
  5. doi Biological and prognostic associations of miR-205 and let-7b in breast cancer revealed by in situ hybridization analysis of micro-RNA expression in arrays of archival tumour tissue
    John Le Quesne
    Cancer Research UK, Cambridge Research Institute and Department of Oncology, University of Cambridge, UK
    J Pathol 227:306-14. 2012
  6. pmc ZNF703 is a common Luminal B breast cancer oncogene that differentially regulates luminal and basal progenitors in human mammary epithelium
    Daniel G Holland
    Cancer Research UK, Cambridge Research Institute, Cambridge, UK
    EMBO Mol Med 3:167-80. 2011

Collaborators

Detail Information

Publications6

  1. pmc Astronomical algorithms for automated analysis of tissue protein expression in breast cancer
    H R Ali
    Department of Oncology, University of Cambridge, Cambridge CB1 9RN, UK
    Br J Cancer 108:602-12. 2013
    ..Although TMAs have the potential to facilitate protein expression profiling on a scale to rival experiments of tumour transcriptomes, the bottleneck and imprecision of manually scoring TMAs has impeded progress...
  2. pmc Aurora kinase A outperforms Ki67 as a prognostic marker in ER-positive breast cancer
    H R Ali
    Department of Oncology, University of Cambridge, Cambridge CB1 9RN, UK
    Br J Cancer 106:1798-806. 2012
    ..Proliferation has emerged as a major prognostic factor in luminal breast cancer. The immunohistochemical (IHC) proliferation marker Ki67 has been most extensively investigated but has not gained widespread clinical acceptance...
  3. doi A Ki67/BCL2 index based on immunohistochemistry is highly prognostic in ER-positive breast cancer
    H Raza Ali
    Department of Oncology, University of Cambridge, Cambridge, CB1 9RN, UK
    J Pathol 226:97-107. 2012
    ..0; 95% CI, 1.4-2.9; p < 0.001). Ki67 and BCL2 can be effectively combined to produce an index which is an independent predictor of BCSS in ER-positive breast cancer, enhancing their potential prognostic utility...
  4. pmc Cancer stem cell markers in breast cancer: pathological, clinical and prognostic significance
    H Raza Ali
    Department of Oncology, University of Cambridge, Cambridge CB1 9RN, UK
    Breast Cancer Res 13:R118. 2011
    ..We set out to establish the clinical relevance of breast CSC markers by profiling a large cohort of breast tumours in tissue microarrays (TMAs) using immunohistochemistry (IHC)...
  5. doi Biological and prognostic associations of miR-205 and let-7b in breast cancer revealed by in situ hybridization analysis of micro-RNA expression in arrays of archival tumour tissue
    John Le Quesne
    Cancer Research UK, Cambridge Research Institute and Department of Oncology, University of Cambridge, UK
    J Pathol 227:306-14. 2012
    ..miR-205 is associated with tumours of ductal morphology and is of significant positive prognostic value within these tumours. We propose that the expression of miR-205 may contribute to ductal tumour morphology...
  6. pmc ZNF703 is a common Luminal B breast cancer oncogene that differentially regulates luminal and basal progenitors in human mammary epithelium
    Daniel G Holland
    Cancer Research UK, Cambridge Research Institute, Cambridge, UK
    EMBO Mol Med 3:167-80. 2011
    ..Taken together, these data strongly point to ZNF703 as a novel oncogene in Luminal B breast cancer...