Rob Shave

Summary

Affiliation: Brunel University
Country: UK

Publications

  1. ncbi request reprint The influence of exercise upon cardiac biomarkers: a practical guide for clinicians and scientists
    Rob Shave
    Brunel University, Uxbridge, Middlesex, UK
    Curr Med Chem 14:1427-36. 2007
  2. doi request reprint A comparison of Doppler, tissue Doppler imaging, and strain rate imaging in the assessment of postexercise left ventricular function
    Rob Shave
    Centre for Sports Medicine and Human Performance, Brunel University, Uxbridge, Middlesex UB83PH, UK
    Appl Physiol Nutr Metab 34:33-9. 2009
  3. ncbi request reprint Exercise-induced cardiac troponin T release: a meta-analysis
    Robert Shave
    Centre for Sports Medicine and Human Performance, Brunel University, Uxbridge, United Kingdom
    Med Sci Sports Exerc 39:2099-106. 2007
  4. doi request reprint Postexercise changes in left ventricular function: the evidence so far
    Rob Shave
    Centre for Sports Medicine and Human Performance, Brunel University, London, United Kingdom
    Med Sci Sports Exerc 40:1393-9. 2008
  5. ncbi request reprint The impact of prolonged exercise in a cold environment upon cardiac function
    Robert Shave
    Department of Sport Sciences, Brunel University, Uxbridge, Middlesex, United Kingdom
    Med Sci Sports Exerc 36:1522-7. 2004
  6. ncbi request reprint Altered cardiac function and minimal cardiac damage during prolonged exercise
    Robert Shave
    Department of Sport Sciences, Brunel University, Uxbridge, UK
    Med Sci Sports Exerc 36:1098-103. 2004
  7. pmc Effect of prolonged exercise in a hypoxic environment on cardiac function and cardiac troponin T
    R E Shave
    Brunel University, Uxbridge, Middlesex, UK
    Br J Sports Med 38:86-8. 2004
  8. ncbi request reprint Novel application of flow propagation velocity and ischaemia-modified albumin in analysis of postexercise cardiac function in man
    Natalie Middleton
    Centre for Sports Medicine and Human Performance, Brunel University, London, UK
    Exp Physiol 91:511-9. 2006
  9. doi request reprint Left ventricular mechanical limitations to stroke volume in healthy humans during incremental exercise
    Eric J Stöhr
    Centre for Sports Medicine and Human Performance, Brunel University, Uxbridge, United Kingdom
    Am J Physiol Heart Circ Physiol 301:H478-87. 2011
  10. ncbi request reprint Effect of preload augmentation on pulsed wave and tissue Doppler echocardiographic indices of diastolic function after a marathon
    Emma Hart
    Center for Sports Medicine and Human Performance, Brunel University, London, UK
    J Am Soc Echocardiogr 20:1393-9. 2007

Detail Information

Publications26

  1. ncbi request reprint The influence of exercise upon cardiac biomarkers: a practical guide for clinicians and scientists
    Rob Shave
    Brunel University, Uxbridge, Middlesex, UK
    Curr Med Chem 14:1427-36. 2007
    ..We will also address the clinical relevance of such exercise-induced perturbations...
  2. doi request reprint A comparison of Doppler, tissue Doppler imaging, and strain rate imaging in the assessment of postexercise left ventricular function
    Rob Shave
    Centre for Sports Medicine and Human Performance, Brunel University, Uxbridge, Middlesex UB83PH, UK
    Appl Physiol Nutr Metab 34:33-9. 2009
    ..This varied response likely reflects the complexities of cardiac function and highlights the need to adopt a multimodality approach when assessing cardiac function following exercise...
  3. ncbi request reprint Exercise-induced cardiac troponin T release: a meta-analysis
    Robert Shave
    Centre for Sports Medicine and Human Performance, Brunel University, Uxbridge, United Kingdom
    Med Sci Sports Exerc 39:2099-106. 2007
    ..Release of cTnT has been demonstrated in several small studies after endurance exercise. The purpose of this study was to explore, using a meta-analytic approach, the incidence of postexercise cTnT release after endurance exercise...
  4. doi request reprint Postexercise changes in left ventricular function: the evidence so far
    Rob Shave
    Centre for Sports Medicine and Human Performance, Brunel University, London, United Kingdom
    Med Sci Sports Exerc 40:1393-9. 2008
    ..Accordingly, we draw together the common findings from this growing body of research in an attempt to reach a consensus regarding the influence of prolonged exercise on LV function...
  5. ncbi request reprint The impact of prolonged exercise in a cold environment upon cardiac function
    Robert Shave
    Department of Sport Sciences, Brunel University, Uxbridge, Middlesex, United Kingdom
    Med Sci Sports Exerc 36:1522-7. 2004
    ..The purpose of the present study was to examine the impact of cold exposure coupled with prolonged exercise upon postexercise left ventricular (LV) function and markers of myocardial damage...
  6. ncbi request reprint Altered cardiac function and minimal cardiac damage during prolonged exercise
    Robert Shave
    Department of Sport Sciences, Brunel University, Uxbridge, UK
    Med Sci Sports Exerc 36:1098-103. 2004
    ..The purpose of the present study was to examine markers of cardiac function and cardiac damage during a simulated half-ironman triathlon in highly trained athletes...
  7. pmc Effect of prolonged exercise in a hypoxic environment on cardiac function and cardiac troponin T
    R E Shave
    Brunel University, Uxbridge, Middlesex, UK
    Br J Sports Med 38:86-8. 2004
    ..Exercise induced cardiac fatigue has recently been observed after prolonged exercise. A moderate to high altitude has been suggested as a possible stimulus in the genesis of such cardiac fatigue...
  8. ncbi request reprint Novel application of flow propagation velocity and ischaemia-modified albumin in analysis of postexercise cardiac function in man
    Natalie Middleton
    Centre for Sports Medicine and Human Performance, Brunel University, London, UK
    Exp Physiol 91:511-9. 2006
    ..Future studies in this area should investigate alternative diagnostic tools for the detection of transient ischaemia, and other potential mechanisms, in order to extend the understanding of this phenomenon...
  9. doi request reprint Left ventricular mechanical limitations to stroke volume in healthy humans during incremental exercise
    Eric J Stöhr
    Centre for Sports Medicine and Human Performance, Brunel University, Uxbridge, United Kingdom
    Am J Physiol Heart Circ Physiol 301:H478-87. 2011
    ..However, LV twist mechanics do not appear to be the sole factor limiting LV output, since EDV reaches its maximum before the plateau in LV twist mechanics, suggesting additional limitations in diastolic filling to the heart...
  10. ncbi request reprint Effect of preload augmentation on pulsed wave and tissue Doppler echocardiographic indices of diastolic function after a marathon
    Emma Hart
    Center for Sports Medicine and Human Performance, Brunel University, London, UK
    J Am Soc Echocardiogr 20:1393-9. 2007
    ..The mechanisms underlying alterations in left ventricular diastolic function after a marathon are unknown and may be a consequence of a reduced preload...
  11. ncbi request reprint Left ventricular function immediately following prolonged exercise: A meta-analysis
    Natalie Middleton
    Centre for Sports Medicine and Human Performance, Brunel University, Middlesex, United Kingdom
    Med Sci Sports Exerc 38:681-7. 2006
    ..The purpose of this meta-analysis was to quantify all data fulfilling the specified inclusion criteria, examining the short-term effect of prolonged endurance exercise on left ventricular function...
  12. doi request reprint Changes in respiratory muscle and lung function following marathon running in man
    Emma Ross
    Centre for Sports Medicine and Human Performance, Brunel University, Uxbridge, UK
    J Sports Sci 26:1295-301. 2008
    ..Our results confirm that prolonged moderate-intensity exercise induces inspiratory muscle fatigue. Furthermore, they suggest that the relative intensity of inspiratory muscle work during exercise makes some contribution to leg fatigue...
  13. doi request reprint Dehydration reduces left ventricular filling at rest and during exercise independent of twist mechanics
    Eric J Stöhr
    Centre for Sports Medicine and Human Performance, Brunel University, West London, United Kingdom
    J Appl Physiol 111:891-7. 2011
    ..The concomitant maintenance of LV mechanics suggests that the decrease in LV filling, and consequently ejection, is likely caused by the reduction in blood volume and/or diminished filling time rather than impaired LV function...
  14. pmc Beta-adrenergic receptor desensitization in man: insight into post-exercise attenuation of cardiac function
    Emma Hart
    Centre for Sports Medicine and Human Performance, Brunel University, Uxbridge, Middlesex UB8 3PH, UK, and Copenhagen Muscle Research Centre, Department of Anaesthesia, Rigshospitalet, University of Copenhagen, Denmark
    J Physiol 577:717-25. 2006
    ..05). Desensitization of the beta-AR contributes to an attenuated left ventricular systolic but not diastolic function following prolonged exercise...
  15. doi request reprint Exercise-induced cardiac troponin elevation: evidence, mechanisms, and implications
    Rob Shave
    Brunel University, Uxbridge, Middlesex, United Kingdom
    J Am Coll Cardiol 56:169-76. 2010
    ..This paper will review the biochemistry, prevalence, potential mechanisms, and management of patients with exercise-induced cTn elevations...
  16. ncbi request reprint Corticomotor excitability contributes to neuromuscular fatigue following marathon running in man
    Emma Z Ross
    Centre for Sports Medicine and Human Performance, Brunel University, Uxbridge, Middlesex, UB8 3PH, UK
    Exp Physiol 92:417-26. 2007
    ..05). All measures had returned to baseline values after 24 h. These results suggest that fatigue was attributable to both a disturbance of the contractile apparatus within the muscle and submaximal output from the motor cortex...
  17. ncbi request reprint Cardiac troponin I is released following high-intensity short-duration exercise in healthy humans
    Rob Shave
    Brunel University, Uxbridge, Middlesex, UK
    Int J Cardiol 145:337-9. 2010
    ..These data are the first to show that cTnI can be released following short-duration high-intensity exercise. Clinicians should be aware that exercise-induced release of cTnI is not limited to prolonged endurance activity...
  18. ncbi request reprint Evidence of exercise-induced cardiac dysfunction and elevated cTnT in separate cohorts competing in an ultra-endurance mountain marathon race
    R E Shave
    British Olympic Medical Centre, Northwick Park Hospital, Harrow, Middlesex, UK
    Int J Sports Med 23:489-94. 2002
    ..The elevation of cTnT above the 99th percentile in the present study is suggestive of minimal myocardial damage. The clinical significance of and exact mechanism responsible for such damage remains to be elucidated...
  19. pmc Exercise induced neurally mediated syncope in an elite rower: a treatment dilemma
    G Whyte
    British Olympic Medical Centre, Northwick Park Hospital, Harrow, Middlesex, UK
    Br J Sports Med 38:84-5. 2004
  20. ncbi request reprint Myocardial stress after competitive exercise in professional road cyclists
    Robert Shave
    Med Sci Sports Exerc 36:738; author reply 739. 2004
  21. pmc Mitral annular myocardial velocity assessment of segmental left ventricular diastolic function after prolonged exercise in humans
    Keith George
    Research Institute for Sport and Exercise Sciences, Liverpool John Moores University, UK
    J Physiol 569:305-13. 2005
    ..4 +/- 0.8 and 3.3 +/- 0.7, respectively) suggests that the depression in diastolic function is likely to be due to altered relaxation of the left ventricle; however, the exact aetiology of this change remains to be determined...
  22. ncbi request reprint Impact of repeated prolonged exercise bouts on cardiac function and biomarkers
    Natalie Middleton
    Centre for Sports Medicine and Human Performance, Brunel University, London, United Kingdom
    Med Sci Sports Exerc 39:83-90. 2007
    ..The present study examined the impact of repeated bouts of prolonged (< 60 min) exercise on left ventricular function and cardiac biomarkers...
  23. ncbi request reprint The cardiospecificity of the third-generation cTnT assay after exercise-induced muscle damage
    Robert Shave
    British Olympic Medical Centre, Northwick Park, Harrow, London, UK
    Med Sci Sports Exerc 34:651-4. 2002
    ....
  24. ncbi request reprint Impact of marathon running on cardiac structure and function in recreational runners
    Gregory Whyte
    Olympic Medical Institute, Northwick Park Hospital, Watford Road, Harrow HA1 3UJ, UK
    Clin Sci (Lond) 108:73-80. 2005
    ..The mechanism(s) underpinning the altered function and appearance of cTnT appear unrelated to reactive oxygen species...
  25. ncbi request reprint Postexercise left ventricular function and cTnT in recreational marathon runners
    Keith George
    Research Institute for Sport and Exercise Science, Henry Cotton Campus, Liverpool John Moores University, Liverpool, United Kingdom
    Med Sci Sports Exerc 36:1709-15. 2004
    ..To assess the impact of prolonged exercise on left ventricular (LV) function and the appearance of cardiac troponin T (cTnT) in older and recreational athletes...
  26. ncbi request reprint The impact of marathon running upon ventricular function as assessed by 2D, Doppler, and tissue-Doppler echocardiography
    David Oxborough
    Cardiac Ultrasound Department, Leeds General Infirmary, Leeds, UK
    Echocardiography 23:635-41. 2006
    ..Conversely, a reduction in diastolic function was observed in both ventricles for which a mechanism has yet to be deduced...