E J Routledge
Affiliation: Brunel University
- Some alkyl hydroxy benzoate preservatives (parabens) are estrogenicE J Routledge
Department of Biology and Biochemistry, Brunel University, Uxbridge, Middlesex, United Kingdom
Toxicol Appl Pharmacol 153:12-9. 1998..The acquisition of such data is a prerequisite to the derivation of reliable estimates of the possible human risk of exposure to parabens...
- Differential effects of xenoestrogens on coactivator recruitment by estrogen receptor (ER) alpha and ERbetaE J Routledge
Department of Biological Sciences, Brunel University, Uxbridge, Middlesex UB8 3PH, UK
J Biol Chem 275:35986-93. 2000..We conclude that ligand-dependent differences in the ability of ERalpha and ERbeta to recruit coactivator proteins may contribute to the complex tissue-dependent agonistic/antagonistic responses observed with certain xenoestrogens...
- Issues arising when interpreting results from an in vitro assay for estrogenic activityN Beresford
Department of Biological Sciences, Brunel University, Uxbridge, Middlesex, UB8 3PH, United Kingdom
Toxicol Appl Pharmacol 162:22-33. 2000..Only by using a suite of assays will we minimize the chances of wrongly labeling chemicals as endocrine disruptors...