J S Brown

Summary

Country: UK

Publications

  1. ncbi request reprint First report of elective selective neck dissection in the management of squamous cell carcinoma of the maxillary sinus
    James S Brown
    Regional Head and Neck Unit, Aintree University Hospital, Lower Lane, Liverpool L9 7AL, United Kingdom
    Br J Oral Maxillofac Surg 51:103-7. 2013
  2. doi request reprint Management of the neck and regional recurrence in squamous cell carcinoma of the maxillary alveolus and hard palate compared with other sites in the oral cavity
    James S Brown
    Regional Head and Neck Unit, Aintree University Hospital, Lower Lane, Liverpool, United Kingdom
    Head Neck 35:265-9. 2013
  3. doi request reprint Systematic review of the current evidence in the use of postoperative radiotherapy for oral squamous cell carcinoma
    J S Brown
    Liverpool University, United Kingdom
    Br J Oral Maxillofac Surg 50:481-9. 2012
  4. ncbi request reprint A comparison of tongue and soft palate squamous cell carcinoma treated by primary surgery in terms of survival and quality of life outcomes
    J S Brown
    Regional Maxillofacial Unit, University Hospital Aintree, Longmoor Lane, Liverpool L9 7AL, UK
    Int J Oral Maxillofac Surg 35:208-14. 2006
  5. ncbi request reprint Indications for the scapular flap in reconstructions of the head and neck
    James Brown
    Department of Oral and Maxillofacial Surgery, University Hospital Aintree, Lower Lane, Liverpool L9 7AL, United Kingdom
    Br J Oral Maxillofac Surg 48:331-7. 2010
  6. doi request reprint Reconstruction of the maxilla and midface: introducing a new classification
    James S Brown
    Department of Head and Neck Surgery, University Hospital Aintree, Liverpool, UK
    Lancet Oncol 11:1001-8. 2010
  7. ncbi request reprint Trends in head and neck microvascular reconstructive surgery in Liverpool (1992-2001)
    J S Brown
    Regional Maxillofacial Unit, University Hospital Aintree, Lower Lane, Liverpool, UK
    Br J Oral Maxillofac Surg 44:364-70. 2006
  8. ncbi request reprint A new guide to mandibular resection for oral squamous cell carcinoma based on the Cawood and Howell classification of the mandible
    J Brown
    Regional Maxillofacial Unit, University Hospital Aintree, Lower Lane, Liverpool L9 7AL, UK
    Int J Oral Maxillofac Surg 34:834-9. 2005
  9. ncbi request reprint A comparison of outcomes for patients with oral squamous cell carcinoma at intermediate risk of recurrence treated by surgery alone or with post-operative radiotherapy
    J S Brown
    Regional Maxillofacial Unit, University Hospital Aintree, Lower Lane, Liverpool L9 7AL, United Kingdom
    Oral Oncol 43:764-73. 2007
  10. doi request reprint Prognostic importance of site in squamous cell carcinoma of the buccal mucosa
    R J Shaw
    Department of Surgery and Oncology, University of Liverpool, Liverpool, UK
    Br J Oral Maxillofac Surg 47:356-9. 2009

Collaborators

Detail Information

Publications37

  1. ncbi request reprint First report of elective selective neck dissection in the management of squamous cell carcinoma of the maxillary sinus
    James S Brown
    Regional Head and Neck Unit, Aintree University Hospital, Lower Lane, Liverpool L9 7AL, United Kingdom
    Br J Oral Maxillofac Surg 51:103-7. 2013
    ..Future research may indicate fewer radiotherapy fields for necks with pathologically clear nodes after elective selective neck dissection...
  2. doi request reprint Management of the neck and regional recurrence in squamous cell carcinoma of the maxillary alveolus and hard palate compared with other sites in the oral cavity
    James S Brown
    Regional Head and Neck Unit, Aintree University Hospital, Lower Lane, Liverpool, United Kingdom
    Head Neck 35:265-9. 2013
    ..The aim of this article was to assess the management of the neck and regional recurrence for squamous cell carcinoma of the maxillary alveolus and hard palate (n = 43) and compare that to the rest of the oral cancer sites (n = 465)...
  3. doi request reprint Systematic review of the current evidence in the use of postoperative radiotherapy for oral squamous cell carcinoma
    J S Brown
    Liverpool University, United Kingdom
    Br J Oral Maxillofac Surg 50:481-9. 2012
    ..Knowing that PORT increases morbidity and reduces salvage rates and options for treating recurrent disease, this difference in overall survival emphasises the need for randomised studies or a re-evaluation of our current protocols...
  4. ncbi request reprint A comparison of tongue and soft palate squamous cell carcinoma treated by primary surgery in terms of survival and quality of life outcomes
    J S Brown
    Regional Maxillofacial Unit, University Hospital Aintree, Longmoor Lane, Liverpool L9 7AL, UK
    Int J Oral Maxillofac Surg 35:208-14. 2006
    ..This finding extends the role of functional surgery in the oropharynx for which primary radiotherapy is often preferred to preserve function...
  5. ncbi request reprint Indications for the scapular flap in reconstructions of the head and neck
    James Brown
    Department of Oral and Maxillofacial Surgery, University Hospital Aintree, Lower Lane, Liverpool L9 7AL, United Kingdom
    Br J Oral Maxillofac Surg 48:331-7. 2010
    ..We present a consecutive series of 46 patients who document the use of this option in routine head and neck practice...
  6. doi request reprint Reconstruction of the maxilla and midface: introducing a new classification
    James S Brown
    Department of Head and Neck Surgery, University Hospital Aintree, Liverpool, UK
    Lancet Oncol 11:1001-8. 2010
    ..We review the current options and our own experience over the past 15 years in an attempt to rationalise the management of these defects...
  7. ncbi request reprint Trends in head and neck microvascular reconstructive surgery in Liverpool (1992-2001)
    J S Brown
    Regional Maxillofacial Unit, University Hospital Aintree, Lower Lane, Liverpool, UK
    Br J Oral Maxillofac Surg 44:364-70. 2006
    ..Improving reliability of tissue transfer remains an important aim, and further development of reliable objective methods of monitoring of flaps is required...
  8. ncbi request reprint A new guide to mandibular resection for oral squamous cell carcinoma based on the Cawood and Howell classification of the mandible
    J Brown
    Regional Maxillofacial Unit, University Hospital Aintree, Lower Lane, Liverpool L9 7AL, UK
    Int J Oral Maxillofac Surg 34:834-9. 2005
    ..A simple guide is suggested for mandibular resection taking into account the pre-operative investigations, the estimation of invasion clinically, and the Cawood and Howell classification of ridge resorption...
  9. ncbi request reprint A comparison of outcomes for patients with oral squamous cell carcinoma at intermediate risk of recurrence treated by surgery alone or with post-operative radiotherapy
    J S Brown
    Regional Maxillofacial Unit, University Hospital Aintree, Lower Lane, Liverpool L9 7AL, United Kingdom
    Oral Oncol 43:764-73. 2007
    ..A randomised trial comparing a watch and wait policy to postoperative radiotherapy in patients with an intermediate risk of recurrence is required to confirm the trend indicated in this retrospective data...
  10. doi request reprint Prognostic importance of site in squamous cell carcinoma of the buccal mucosa
    R J Shaw
    Department of Surgery and Oncology, University of Liverpool, Liverpool, UK
    Br J Oral Maxillofac Surg 47:356-9. 2009
    ..34). We conclude that site had little influence on prognosis, and that the poor outcome of buccal cancers reported from other centres has not been replicated in our series...
  11. ncbi request reprint Health-related quality of life and clinical function after primary surgery for oral cancer
    S N Rogers
    Regional Maxillofacial Unit, University Hospital Aintree, Aintree Trust, Liverpool, UK
    Br J Oral Maxillofac Surg 40:11-8. 2002
    ..The differential in respect of baseline function was present at all three time points in each patient group. This suggests that functional deficits at presentation persist following treatment...
  12. doi request reprint Salvage outcomes of free tissue transfer in Liverpool: trends over 18 years (1992-2009)
    M W Ho
    Regional Maxillofacial Unit, University Hospital Aintree, Liverpool, United Kingdom
    Br J Oral Maxillofac Surg 50:13-8. 2012
    ..Overall survival (1992-2009) for composite free flaps (93%) was lower than for fasciocutaneous or perforator free flaps (96%). Between 2005 and 2009 our overall free flap survival rate was 98%...
  13. ncbi request reprint Vascularized iliac crest with internal oblique muscle for immediate reconstruction after maxillectomy
    J S Brown
    Regional Maxillofacial Unit, University Hospital Aintree, Liverpool, UK
    Br J Oral Maxillofac Surg 40:183-90. 2002
    ..This flap provides a base to enable full dental and facial prosthetic rehabilitation with either implant-retained or conventional prostheses...
  14. ncbi request reprint Factors that influence the method of mandibular resection in the management of oral squamous cell carcinoma
    J S Brown
    Regional Maxillofacial Unit, University Hospital Aintree, Liverpool, UK
    Br J Oral Maxillofac Surg 40:275-84. 2002
    ..Angling the horizontal rim resection to take into account tumour entry at the point of contact will help to ensure a clear bone margin if a conservative approach to mandibular resection is an option...
  15. ncbi request reprint The prognostic implications of the surgical margin in oral squamous cell carcinoma
    D N Sutton
    Department of Maxillofacial Surgery, University Hospital Aintree, Lower Lane, Liverpool, L9 7AL, UK
    Int J Oral Maxillofac Surg 32:30-4. 2003
    ..These results imply that close surgical margins in OSCC could be regarded as an indictor of aggressive disease...
  16. ncbi request reprint Clinical function after primary surgery for oral and oropharyngeal cancer: an 11-item examination
    S N Rogers
    Regional Maxillofacial Unit, University Hospital Aintree, Aintree Trust, Liverpool, UK
    Br J Oral Maxillofac Surg 40:1-10. 2002
    ..A simple clinical examination provides a rapid assessment of function that can be used in conjunction with validated questionnaires to provide a more comprehensive evaluation of outcome...
  17. ncbi request reprint Factors that influence the outcome of salvage in free tissue transfer
    J S Brown
    Regional Centre for Maxillofacial Surgery, University Hospital Aintree, Longmoor Lane, Liverpool L9 7AL, UK
    Br J Oral Maxillofac Surg 41:16-20. 2003
    ..The success of salvage techniques for free tissue transfer is well documented. The aim of this study was to identify factors that influenced the results of salvage operations in a group of patients who required early exploration...
  18. ncbi request reprint The relationship between length of stay and health-related quality of life in patients treated by primary surgery for oral and oropharyngeal cancer
    S N Rogers
    Regional Maxillofacial Unit, University Hospital Aintree, Aintree Trust, Liverpool, UK
    Int J Oral Maxillofac Surg 30:209-15. 2001
    ....
  19. pmc The influence of allogenic blood transfusion in patients having free-flap primary surgery for oral and oropharyngeal squamous cell carcinoma
    T Szakmany
    Intensive Care Unit, University Hospital Aintree, Liverpool L9 1AL, UK
    Br J Cancer 94:647-53. 2006
    ..Therefore, every effort should be made to limit the amount of blood transfused to the minimum requirement...
  20. ncbi request reprint Timing and presentation of recurrent oral and oropharyngeal squamous cell carcinoma and awareness in the outpatient clinic
    D Kissun
    Regional Maxillofacial Unit, University Hospital Aintree, Fazakerley, Liverpool, UK
    Br J Oral Maxillofac Surg 44:371-6. 2006
    ..This study has emphasised the need for close clinical follow-up of patients previously treated for oral/oropharyngeal SCC if recurrent tumours are to be discovered and treated at the earliest opportunity...
  21. ncbi request reprint Predictors of speech and swallowing function following primary surgery for oral and oropharyngeal cancer
    A C Zuydam
    Speech and Language Therapy Department, University Hospital Aintree, Aintree Hospitals NHS Trust, Liverpool, UK
    Clin Otolaryngol 30:428-37. 2005
    ....
  22. ncbi request reprint A comparison of aesthetic, functional and patient subjective outcomes following lip-split mandibulotomy and mandibular lingual releasing access procedures
    J C Devine
    Regional Maxillofacial Unit, University Hospital Aintree, UK
    Int J Oral Maxillofac Surg 30:199-204. 2001
    ..Previous concerns about a possible detrimental effect on appearance following lip-split, were not borne out in this study...
  23. ncbi request reprint Evidence for imaging the mandible in the management of oral squamous cell carcinoma: a review
    J S Brown
    Regional Maxillofacial Unit, University Hospital Aintree, Longmoor Lane, Liverpool L9 A7L, UK
    Br J Oral Maxillofac Surg 39:411-8. 2001
    ....
  24. ncbi request reprint An assessment of deprivation as a factor in the delays in presentation, diagnosis and treatment in patients with oral and oropharyngeal squamous cell carcinoma
    S N Rogers
    Regional Maxillofacial Unit, University Hospital Aintree, Fazakerley, Liverpool, UK
    Oral Oncol 43:648-55. 2007
    ..Deprivation did not seem to significantly lengthen presentation or referral however it may be that it is associated with more rapidly growing tumours...
  25. ncbi request reprint Flap monitoring after head and neck reconstruction: evaluating an observation protocol
    J C Devine
    Practice Development Unit, Regional Services for Maxillofacial Surgery, University Hospital Aintree, Liverpool, UK
    J Wound Care 10:525-9. 2001
    ..It is recommended that flaps are monitored hourly for the first 72 postoperative hours and observations recorded on a chart...
  26. ncbi request reprint Rationale for the use of the implantable Doppler probe based on 7 years' experience
    M W Ho
    Regional Maxillofacial Unit, Aintree University Hospital, Liverpool, UK Electronic address
    Br J Oral Maxillofac Surg 52:530-4. 2014
    ..There is not enough evidence to suggest that the implantable doppler reduces the rate of failed flaps in routine low-risk cases, and its value in monitoring high-risk reconstructions require evaluation in a prospective randomised study. ..
  27. ncbi request reprint Repair of the radial free flap donor site with full or partial thickness skin grafts. A prospective randomised controlled trial
    A J Sidebottom
    Regional Maxillofacial Unit, Aintree University Hospital, Liverpool, UK
    Int J Oral Maxillofac Surg 29:194-7. 2000
    ..Provided that an adequate graft is taken, full thickness and partial thickness skin grafts have the same short-term and long-term outcomes in the repair of the radial free flap donor site...
  28. doi request reprint Analysis of time taken to discuss new patients with head and neck cancer in multidisciplinary team meetings
    B J Mullan
    Oral and Maxillofacial Surgery Department, Aintree University Hospital NHS Foundation Trust, Longmoor Lane, Liverpool L9 7AL, United Kingdom University of Liverpool, United Kingdom Electronic address
    Br J Oral Maxillofac Surg 52:128-33. 2014
    ..Further studies may highlight extended discussions on patients with head and neck cancer, which may prompt a review of protocols and current evidence...
  29. doi request reprint Inferior alveolar nerve damage caused by bone wax in third molar surgery
    C Katre
    University Hospital Aintree, Liverpool, UK
    Int J Oral Maxillofac Surg 39:511-3. 2010
    ..The case illustrates the poor resorption qualities of bone wax and the need for other haemostatic agents to achieve haemostasis in dentoalveolar surgery...
  30. pmc Effects of urinary incontinence, comorbidity and race on quality of life outcomes in women
    A I Ragins
    Division of Research, Kaiser Permanente, Oakland, California, USA
    J Urol 179:651-5; discussion 655. 2008
    ....
  31. ncbi request reprint Cervical lymph node metastasis in oral cancer: the importance of even microscopic extracapsular spread
    J A Woolgar
    Oral Pathology Laboratory, Liverpool University Dental Hospital, Pembroke Place, Liverpool L3 5PS, UK
    Oral Oncol 39:130-7. 2003
    ..Extracapsular spread should be incorporated into pathological staging systems. Even microscopic extracapsular spread is of critical importance and must be sought especially in small-volume metastatic disease...
  32. ncbi request reprint Re: Brown JS, Jones DC, Summerwill A et al. Vascularised iliac crest with internal oblique muscle for immediate reconstruction after maxillectomy. Br J Oral Maxillofac Surg 2002; 40: 183-190
    J S Brown
    Br J Oral Maxillofac Surg 41:364. 2003
  33. ncbi request reprint Does weight loss improve incontinence in moderately obese women?
    L L Subak
    Department of Obstetrics, Gynecology, and Reproductive Sciences, University of California, San Francisco, 94143 1688, USA
    Int Urogynecol J Pelvic Floor Dysfunct 13:40-3. 2002
    ..07). The study demonstrated an association between weight reduction and improved urinary incontinence. Weight reduction should be considered for moderately obese women as part of non-surgical therapy for incontinence...
  34. ncbi request reprint Urinary incontinence in elderly women: findings from the Health, Aging, and Body Composition Study
    R A Jackson
    Department of Obstetrics, Gynecology and Reproductive Sciences, University of California, San Francisco, USA
    Obstet Gynecol 104:301-7. 2004
    ..To estimate the prevalence of and risk factors for stress and urge incontinence in a biracial sample of well-functioning older women...
  35. pmc Promoter methylation of P16, RARbeta, E-cadherin, cyclin A1 and cytoglobin in oral cancer: quantitative evaluation using pyrosequencing
    R J Shaw
    Molecular Genetics and Oncology Group, School of Dental Sciences, University of Liverpool, Liverpool L69 3GN, UK
    Br J Cancer 94:561-8. 2006
    ..Significant tumour specific methylation of cyclin A1 promoter was also seen. Cytoglobin is a novel candidate tumour suppressor gene highly methylated in upper aero-digestive tract squamous cancer...
  36. pmc Urinary incontinence and pelvic floor dysfunction in Asian-American women
    A J Huang
    Division of General Medicine, San Francisco Veterans Affairs Medical Center, 4150 Clement Street, VAMC 111A1, San Francisco, CA 94121, USA
    Am J Obstet Gynecol 195:1331-7. 2006
    ..The objective of the study was to describe the prevalence, risk factors, and impact of urinary incontinence and other pelvic floor disorders among Asian-American women...
  37. ncbi request reprint Cost-effectiveness of migraine prevention: the case of topiramate in the UK
    J S Brown
    Harvard Medical School Harvard Pilgrim Health Care, Department of Ambulatory Care and Prevention, Boston, MA, USA
    Cephalalgia 26:1473-82. 2006
    ..This analysis suggests that topiramate is a cost-effective treatment for migraine prevention compared with no preventive treatment...