A M Peters

Summary

Affiliation: Brighton and Sussex Medical School
Country: UK

Publications

  1. ncbi Research in nuclear medicine
    A M Peters
    Nucl Med Commun 25:535-7. 2004
  2. ncbi Estimation of extracellular fluid volume in children
    A Michael Peters
    Royal Sussex County Hospital, Audrey Emerton Building, Eastern Road, Brighton, BN2 5BE, UK
    Pediatr Nephrol 27:1149-55. 2012
  3. ncbi The reliability of glomerular filtration rate measured from plasma clearance: a multi-centre study of 1,878 healthy potential renal transplant donors
    A Michael Peters
    Department of Nuclear Medicine, Royal Sussex County Hospital, Brighton, UK
    Eur J Nucl Med Mol Imaging 39:715-22. 2012
  4. ncbi Extracellular fluid volume and glomerular filtration rate in 1878 healthy potential renal transplant donors: effects of age, gender, obesity and scaling
    A Michael Peters
    Department of Nuclear Medicine, Royal Sussex County Hospital, Brighton, UK
    Nephrol Dial Transplant 27:1429-37. 2012
  5. ncbi Clinical governance improves the quality of nuclear medicine reporting
    A Michael Peters
    Department of Nuclear Medicine, Royal Sussex County Hospital, Brighton, UK
    Nucl Med Commun 29:999-1001. 2008
  6. ncbi Estimated lean body mass is more appropriate than body surface area for scaling glomerular filtration rate and extracellular fluid volume
    A Michael Peters
    Department of Nuclear Medicine, Royal Sussex County Hospital, Brighton, UK
    Nephron Clin Pract 116:c75-80. 2010
  7. ncbi Slope-only glomerular filtration rate and single-sample glomerular filtration rate as measurements of the ratio of glomerular filtration rate to extracellular fluid volume
    A Michael Peters
    Department of Nuclear Medicine, Royal Sussex County Hospital, Brighton, UK
    Nephrology (Carlton) 15:281-7. 2010
  8. ncbi Use of body surface area for assessing extracellular fluid volume and glomerular filtration rate in obesity
    A Michael Peters
    Nuclear Medicine Department, Harley Street Clinic, London, UK
    Am J Nephrol 31:209-13. 2010
  9. ncbi Evaluation of the Modification of Diet in Renal Disease equation (eGFR) against simultaneous, dual-marker multi-sample measurements of glomerular filtration rate
    A Michael Peters
    Department of Nuclear Medicine, Addenbrooke s Hospital, Cambridge, UK
    Ann Clin Biochem 46:58-64. 2009
  10. ncbi Functional variation in lymph node arrangements within the axilla
    A Michael Peters
    Department of Nuclear Medicine, Addenbrooke s Hospital, Cambridge, United Kingdom
    Lymphat Res Biol 7:139-44. 2009

Collaborators

Detail Information

Publications43

  1. ncbi Research in nuclear medicine
    A M Peters
    Nucl Med Commun 25:535-7. 2004
  2. ncbi Estimation of extracellular fluid volume in children
    A Michael Peters
    Royal Sussex County Hospital, Audrey Emerton Building, Eastern Road, Brighton, BN2 5BE, UK
    Pediatr Nephrol 27:1149-55. 2012
    ..The aim of this study was to compare four height/weight formulae for estimating extracellular fluid volume (eECV) in children against measured extracellular fluid volume (mECV)...
  3. ncbi The reliability of glomerular filtration rate measured from plasma clearance: a multi-centre study of 1,878 healthy potential renal transplant donors
    A Michael Peters
    Department of Nuclear Medicine, Royal Sussex County Hospital, Brighton, UK
    Eur J Nucl Med Mol Imaging 39:715-22. 2012
    ..ECFV is held within narrow limits in healthy subjects, narrower than GFR, and should therefore have a low CV...
  4. ncbi Extracellular fluid volume and glomerular filtration rate in 1878 healthy potential renal transplant donors: effects of age, gender, obesity and scaling
    A Michael Peters
    Department of Nuclear Medicine, Royal Sussex County Hospital, Brighton, UK
    Nephrol Dial Transplant 27:1429-37. 2012
    ..Aim. The aim of this study was to investigate the influence of age, gender, obesity and scaling on glomerular filtration rate (GFR) and extracellular fluid volume (ECV) in healthy subjects...
  5. ncbi Clinical governance improves the quality of nuclear medicine reporting
    A Michael Peters
    Department of Nuclear Medicine, Royal Sussex County Hospital, Brighton, UK
    Nucl Med Commun 29:999-1001. 2008
    ..To assess the quality of nuclear medicine reporting, within a private UK hospital, of five physicians from four different National Health Service trusts and compare it with a similar previous clinical governance exercise...
  6. ncbi Estimated lean body mass is more appropriate than body surface area for scaling glomerular filtration rate and extracellular fluid volume
    A Michael Peters
    Department of Nuclear Medicine, Royal Sussex County Hospital, Brighton, UK
    Nephron Clin Pract 116:c75-80. 2010
    ..To compare body surface area (BSA) with lean body mass (LBM) for scaling extracellular fluid volume (ECV) and glomerular filtration rate (GFR)...
  7. ncbi Slope-only glomerular filtration rate and single-sample glomerular filtration rate as measurements of the ratio of glomerular filtration rate to extracellular fluid volume
    A Michael Peters
    Department of Nuclear Medicine, Royal Sussex County Hospital, Brighton, UK
    Nephrology (Carlton) 15:281-7. 2010
    ..The aims were to redevelop a more transparent equation, show its fundamental similarity with 'slope-only' GFR and compare it with the original equation and with slope-only GFR...
  8. ncbi Use of body surface area for assessing extracellular fluid volume and glomerular filtration rate in obesity
    A Michael Peters
    Nuclear Medicine Department, Harley Street Clinic, London, UK
    Am J Nephrol 31:209-13. 2010
    ..ECV varies less than glomerular filtration rate (GFR) in a clinical population and was therefore used as a surrogate for GFR on the grounds that if BSA is unsuitable for scaling GFR, it will also be unsuitable for ECV...
  9. ncbi Evaluation of the Modification of Diet in Renal Disease equation (eGFR) against simultaneous, dual-marker multi-sample measurements of glomerular filtration rate
    A Michael Peters
    Department of Nuclear Medicine, Addenbrooke s Hospital, Cambridge, UK
    Ann Clin Biochem 46:58-64. 2009
    ..Estimation of glomerular filtration rate (GFR) using plasma creatinine remains controversial, especially when GFR approaches normal values. The aim was to re-examine estimated GFR (eGFR) using dual-reference GFR measurements...
  10. ncbi Functional variation in lymph node arrangements within the axilla
    A Michael Peters
    Department of Nuclear Medicine, Addenbrooke s Hospital, Cambridge, United Kingdom
    Lymphat Res Biol 7:139-44. 2009
    ..The commonest is a single linear chain, then a chain branching into two linear chains, and, least common, a network...
  11. ncbi A brief history of cell labelling
    A M Peters
    School of Applied Physiology, Brighton and Sussex Medical School, Royal Sussex County Hospital, Eastern Road, Brighton BN2 4BE, UK
    Q J Nucl Med Mol Imaging 49:304-7. 2005
    ..Since the current-day applications of labelled platelets and leukocytes depend on a clear understanding of cell kinetics, these classical studies are important and relevant to the history of cell labelling...
  12. ncbi Obesity does not accelerate the decline in glomerular filtration rate associated with advancing age
    A M Peters
    Nuclear Medicine, Brighton and Sussex Medical School, Eastern Road, Brighton, UK
    Int J Obes (Lond) 33:379-81. 2009
    ..82 vs 0.95 ml per min per 1.73 m(2) per year and 0.87 vs 1.02 ml per min per 13 l per year). No effect of obesity on renal function was shown. Scaling to BSA did not distort the results...
  13. ncbi Re-evaluation of the new Jodal-Brochner-Mortensen equation for one-pool correction of slope-intercept measurement of glomerular filtration rate
    A Michael Peters
    Department of Nuclear Medicine, Royal Sussex County Hospital, Brighton, UK
    Nucl Med Commun 32:375-80. 2011
    ..However, this study shows that any tracer distribution volume can be substituted for Vo to measure f...
  14. ncbi Extracellular fluid volume and glomerular filtration rate: their relation and variabilities in patients with renal disease and healthy individuals
    A Michael Peters
    Department of Nuclear Medicine, Harley St Clinic, London, UK
    Nucl Med Commun 32:649-53. 2011
    ..Although this requirement is met in healthy individuals, ECV may deviate or vary more in patients with abnormal renal function...
  15. ncbi Why the spleen is a very rare site for metastases from epithelial cancers
    A Michael Peters
    Brighton Sussex Medical School, Department of Nuclear Medicine, Royal Sussex County Hospital, Brighton, UK
    Med Hypotheses 78:26-8. 2012
    ..This leads to the second hypothesis, which is that cancer cells fail to survive in the spleen as a result of these pro-apoptotic signals...
  16. ncbi Estimation of lean body mass in children
    A M Peters
    Department of Nuclear Medicine, Harley St Clinic, London, UK
    Br J Anaesth 106:719-23. 2011
    ..In adults, dosages of some anaesthetic agents are based on lean body mass (LBM) rather than body weight. Our aim was to derive an equation for estimating LBM in children...
  17. ncbi Pegylated liposome-encapsulated doxorubicin and cisplatin enhance the effect of radiotherapy in a tumor xenograft model
    K J Harrington
    Oncology Unit, Imperial College of Science, Technology and Medicine, Hammersmith Hospital, London, United Kingdom
    Clin Cancer Res 6:4939-49. 2000
    ..This study is the first to demonstrate the value of pegylated liposomes as vehicles for the delivery of radiosensitizing drugs in CCRT strategies...
  18. ncbi The effect of irradiation on the biodistribution of radiolabeled pegylated liposomes
    K J Harrington
    ICRF Oncology Unit, Imperial College of Science, Technology and Medicine, Hammersmith Hospital, London, UK
    Int J Radiat Oncol Biol Phys 50:809-20. 2001
    ....
  19. ncbi Single-fraction irradiation has no effect on uptake of radiolabeled pegylated liposomes in a tumor xenograft model
    K J Harrington
    ICRF Oncology Unit, Imperial College of Science, Technology and Medicine, Hammersmith Hospital, London, United Kingdom
    Int J Radiat Oncol Biol Phys 49:1141-8. 2001
    ..These studies were performed with the intention of examining the effect of single-fraction doses of radiotherapy (RT) on the tumor deposition of radiolabeled pegylated liposomes in an animal xenograft tumor model...
  20. ncbi Lymphatic transfer studies with immunoglobulin scintigraphy after axillary surgery
    T M Bennett Britton
    Cambridge Breast Unit, Addenbrooke s Hospital, Cambridge University Hospitals NHS Trust, Cambridge, UK
    Eur J Surg Oncol 33:1052-60. 2007
    ..The study objective was to investigate the effects of axillary lymph node clearance surgery on the function and morphology of the lymphatic system of the upper limb in women with breast cancer...
  21. ncbi Reliability of the MDRD method for estimating glomerular filtration rate in relation to gender, body mass index and extracellular fluid volume
    N J Bird
    Department of Nuclear Medicine, Addenbrooke s Hospital, Cambridge, UK
    Eur J Clin Invest 38:486-93. 2008
    ....
  22. ncbi Effective targeting of solid tumors in patients with locally advanced cancers by radiolabeled pegylated liposomes
    K J Harrington
    Oncology Unit, Imperial College of Science, Technology and Medicine, Hammersmith Hospital, London, United Kingdom
    Clin Cancer Res 7:243-54. 2001
    ..6:1, in salivary gland by 5.6:1, in muscle by 8.3:1, and in fat by 10.8:1. These data strongly support the development of pegylated liposomal agents for the treatment of solid tumors, particularly those of the head and neck...
  23. ncbi Phase I-II study of pegylated liposomal cisplatin (SPI-077) in patients with inoperable head and neck cancer
    K J Harrington
    ICRF Laboratory of Molecular Therapy, Imperial College of Science, Technology and Medicine, Hammersmith Hospital, London, UK
    Ann Oncol 12:493-6. 2001
    ..Pegylated liposomes localise to solid cancers and may deliver radiosensitizing agents preferentially to tumour tissue, potentially improving the therapeutic ratio of CCRT...
  24. ncbi A pilot study of dual-isotope lymphoscintigraphy for breast sentinel node biopsy comparing intradermal and intraparenchymal injection
    J C Fowler
    Department of Nuclear Medicine, Addenbrooke s Hospital, Cambridge, UK
    Eur J Surg Oncol 35:1041-7. 2009
    ..To explore this, we developed a dual-isotope technique to compare the lymphatic drainage basins accessed by intradermal and parenchymal injections...
  25. ncbi Association between glomerular filtration rate and extracellular fluid volume in normal subjects and patients with renal impairment
    N J Bird
    Department of Nuclear Medicine, Addenbrooke s Hospital, Cambridge, UK
    Scand J Clin Lab Invest 68:39-49. 2008
    ..When ECV is expanded in patients with renal impairment, however, there is no GFR response, leading to a reduction in GFR/ECV...
  26. ncbi Sympathetic nerve damage as a potential cause of lymphoedema after axillary dissection for breast cancer
    T M Bennett Britton
    Department of Research Oncology, King s College London and Guy s and St Thomas NHS Foundation Trust, Bermondsey Wing, Guy s Hospital, London, UK
    Br J Surg 96:865-9. 2009
    ..Damage to sympathetic nerves during axillary lymph node dissection (ALND), leading to increased capillary fluid filtration, was investigated as a possible contributory factor...
  27. ncbi Comparison between terminal slope rate constant and "slope/intercept" as measures of glomerular filtration rate using the single-compartment simplification
    A M Peters
    Department of Nuclear Medicine, Box 170, Addenbrookes Hospital, Hills Road, Cambridge CB2 2QQ, UK
    Eur J Nucl Med 28:320-6. 2001
    ..This study suggests that, because of the effects of errors in the slope/intercept method that do not affect alpha 2, GFR based on slope only is at least as robust as that based on slope/intercept...
  28. ncbi A simple processing method allowing comparison of renal enhancing volumes derived from standard portal venous phase contrast-enhanced multidetector CT images to derive a CT estimate of differential renal function with equivalent results to nuclear medicin
    J C Fowler
    Department of Radiology, Addenbrooke's Hospital and the University of Cambridge, Cambridge, UK
    Br J Radiol 79:935-42. 2006
    ..This is a simple, practicable processing technique using standard portal venous phase CEMDCT images to quantify differential function. This technique may allow a one-stop CT assessment of both anatomy and function...
  29. ncbi Radioguided occult lesion localisation (ROLL) and sentinel node biopsy for impalpable invasive breast cancer
    A Patel
    Cambridge Breast Unit, Addenbrooke's Hospital, Cambridge, UK
    Eur J Surg Oncol 30:918-23. 2004
    ..CONCLUSIONS: This modification of the previously described ROLL technique is feasible and safe and does not compromise tumour excision or sentinel node detection...
  30. ncbi The kinetic basis of glomerular filtration rate measurement and new concepts of indexation to body size
    A M Peters
    Department of Nuclear Medicine, Addenbrooke s Hospital, Hills Road, Box 170, Cambridge, CB2 2QQ, UK
    Eur J Nucl Med Mol Imaging 31:137-49. 2004
    ..A recently described equation is ECFV=0.02154 x weight(0.6469) x height(0.7236). Indexation to ECFV abolishes differences that arise between children and adults when GFR is indexed to BSA...
  31. ncbi Phase II study of pegylated liposomal doxorubicin (Caelyx) as induction chemotherapy for patients with squamous cell cancer of the head and neck
    K J Harrington
    ICRF Laboratory of Molecular Therapy, Imperial College of Science, Technology and Medicine, Hammersmith Hospital, 150 Du Cane Road, W12 0HS, London, UK
    Eur J Cancer 37:2015-22. 2001
    ..In view of its tumour targeting properties and activity at moderate doses, it may be useful in concomitant chemoradiotherapy strategies for SCCHN...
  32. ncbi Characterization of E-selectin expression in vivo with use of a radiolabeled monoclonal antibody
    E T Keelan
    Department of Medicine, Royal Postgraduate Medical School, Hammersmith Hospital, London, United Kingdom
    Am J Physiol 266:H278-90. 1994
    ....
  33. ncbi Polycystic kidneys and renal transplant imaging
    C J Beadsmoore
    Department of Nuclear Medicine, Addenbrooke's Hospital, Cambridge, UK
    Clin Nucl Med 30:537-9. 2005
    ..This report describes 2 cases of unusual appearance at renography resulting from the native polycystic kidneys...
  34. ncbi Amino acid infusion blocks renal tubular uptake of an indium-labelled somatostatin analogue
    P J Hammond
    Department of Medicine, Royal Postgraduate Medical School, Hammersmith Hospital, London, UK
    Br J Cancer 67:1437-9. 1993
    ....
  35. ncbi Tissue-to-blood transport of radiolabelled immunoglobulin injected into the web spaces of the hands of normal subjects and patients with breast cancer-related lymphoedema
    S J Pain
    Cambridge Breast Unit, Addenbrooke's Hospital, Cambridge, UK
    J Vasc Res 41:183-92. 2004
    ..Significant quantities of radioprotein may escape from the arm via local access to blood. Individual variation in this capacity may explain the regional sparing observed in BCRL...
  36. ncbi A qualitative and quantitative assessment of the impact of three processing algorithms with halving of study count statistics in myocardial perfusion imaging: filtered backprojection, maximal likelihood expectation maximisation and ordered subset expectat
    B N Modi
    Nuclear Medicine Department, Luton and Dunstable NHS Foundation Trust, Luton, UK
    J Nucl Cardiol 19:945-57. 2012
    ..OSEM-RR has not yet been compared with maximal likelihood expectation maximisation (MLEM)...
  37. ncbi Measurement of the extravascular concentration of renal agents following intravenous bolus injection
    A M Peters
    Department of Diagnostic Radiology, Hammersmith Hospital, London, UK
    Nucl Med Commun 15:66-72. 1994
    ..Protein binding was zero for EDTA, 30% for hippuran, 86% for DMSA and 88% for MAG3.(ABSTRACT TRUNCATED AT 250 WORDS)..
  38. ncbi Cerebral neutrophil recruitment, histology, and outcome in acute ischemic stroke: an imaging-based study
    C J S Price
    University of Cambridge Department of Medicine, Hospital, Cambridge, UK
    Stroke 35:1659-64. 2004
    ..We have studied the patterns and temporal profile of cerebral neutrophil recruitment to areas of acute ischemic stroke (IS) and have attempted to correlate this with neurological status and outcome...
  39. ncbi Imaging of multidrug resistance in cancer
    S Dizdarevic
    Department of Nuclear Medicine, Brighton and Sussex University Hospitals NHS Trust, Brighton, UK
    Cancer Imaging 11:1-8. 2011
    ....
  40. ncbi Influence of tumour size on uptake of(111)ln-DTPA-labelled pegylated liposomes in a human tumour xenograft model
    K J Harrington
    ICRF Oncology Unit, Imperial College of Science, Technology and Medicine, Hammersmith Hospital, 150 DuCane Road, London, W12 0HS, UK
    Br J Cancer 83:684-8. 2000
    ..001), consistent with poor or heterogeneous vascularization of larger tumours. These data have important implications for the clinical application of pegylated liposome targeted strategies for solid cancers which are discussed in detail...
  41. ncbi Gamma camera imaging in malignancy
    J W Evans
    Department of Nuclear Medicine, Box 170, Addenbrooke' s Hospital, Hills Road, Cambridge CB2 2QQ, UK
    Eur J Cancer 38:2157-72. 2002
  42. ncbi Sensitivity and specificity of radioisotope right-left shunt measurements and pulse oximetry for the early detection of pulmonary arteriovenous malformations
    R D Thompson
    Department of Respiratory Medicine, Imperial College School of Medicine, Hammersmith Hospital, London, United Kingdom
    Chest 115:109-13. 1999
    ..To assess the effectiveness of pulse oximetry and radioisotope measurement of right-to-left (R-L) shunt for the early detection of pulmonary arteriovenous malformations (PAVMs) in patients with hereditary hemorrhagic telangiectasia (HHT)...
  43. ncbi Case report: imaging of central nervous system sarcoidosis with gallium-67 single photon emission computed tomography
    P R Jarman
    Department of Medicine, Hammersmith Hospital, London, UK
    Br J Radiol 69:192-4. 1996
    ..This technique may be of value in the assessment of patients with sarcoidosis and suspected central nervous system involvement...