Research Topics
| Ken MilesSummaryAffiliation: Brighton and Sussex Medical School Country: UK Publications
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Detail Information
Publications
Colorectal cancer: imaging surveillance following resection of primary tumourKen Miles
Brighton and Sussex Medical School, Brighton, UK
Cancer Imaging 7:S143-9. 2007..Improvements in survival with more aggressive follow up and treatment are likely to demand more accurate imaging techniques in the future...
Current status and guidelines for the assessment of tumour vascular support with dynamic contrast-enhanced computed tomographyK A Miles
Clinical Imaging Sciences Centre, Brighton and Sussex Medical School, University of Sussex, Falmer, BN1 9RR, UK
Eur Radiol 22:1430-41. 2012....- Can imaging help improve the survival of cancer patients?K Miles
Brighton and Sussex Medical School, Brighton BN1 9PX, UK
Cancer Imaging 11:S86-92. 2011..For applications where the improvements in survival are more modest, use of imaging frequently has additional demonstrable benefits including reductions in health care expenditure... - Warburg revisited: imaging tumour blood flow and metabolismK A Miles
Brighton and Sussex Medical School, Brighton, UK
Cancer Imaging 8:81-6. 2008..The potential for vascular metabolic imaging to assess tumour aggression and sub-classify treatment response is highlighted... 
Blood flow-metabolic relationships are dependent on tumour size in non-small cell lung cancer: a study using quantitative contrast-enhanced computer tomography and positron emission tomographyK A Miles
Division of Clinical and Laboratory Sciences, Brighton and Sussex Medical School, University of Sussex, Brighton, BN7 3PB, UK
Eur J Nucl Med Mol Imaging 33:22-8. 2006....- Quantitative contrast-enhanced computed tomography: is there a need for system calibration?Kenneth A Miles
Brighton and Sussex Medical School, University of Sussex, Falmer, Brighton, BN1 9PX, UK
Eur Radiol 17:919-26. 2007.... - Colorectal cancer: texture analysis of portal phase hepatic CT images as a potential marker of survivalKenneth A Miles
Division of Clinical and Laboratory Sciences, Clinical Imaging Sciences Centre, Brighton and Sussex Medical School, University of Sussex, Falmer, Brighton, United Kingdom
Radiology 250:444-52. 2009.... - PET-CT in oncology: making the most of CTK A Miles
Brighton and Sussex Medical School, Brighton, UK
Cancer Imaging 8:S87-93. 2008..Furthermore, specialists working in PET-CT will need CT competencies beyond knowledge of cross-sectional anatomy. CT continues to exhibit rapid evolution and these advances will inevitably impact on the practice of PET-CT... - Perfusion imaging with computed tomography: brain and beyondKenneth A Miles
Division of Clinical and Laboratory Investigation, Brighton and Sussex Medical School, University of Sussex, Falmer Brighton BN1 9PX, United Kingdom
Eur Radiol 16:M37-43. 2006..By exploiting the ability of CT systems to quantify contrast enhancement, CT perfusion imaging uses contrast media to assess vascular physiology and so improve diagnosis, prognosis, treatment selection and therapy monitoring... - Cancer imaging: is it cost-effective?K A Miles
Division of Clinical and Laboratory Sciences, Brighton and Sussex Medical School, University of Sussex, Falmer, Brighton, UK
Cancer Imaging 4:97-103. 2004.... - Diagnostic imaging in undergraduate medical education: an expanding roleK A Miles
Brighton and Sussex Medical School, University of Sussex, Brighton, UK
Clin Radiol 60:742-5. 2005..This article reviews the methods by which diagnostic imaging can be used to support the learning of anatomy and other basic sciences... - Brain perfusion: computed tomography applicationsK A Miles
Division of Clinical and Laboratory Investigation, Brighton and Sussex Medical School, University of Sussex, Falmer, Brighton, UK
Neuroradiology 46:s194-200. 2004..This article reviews the use of CT for imaging cerebral perfusion, highlighting its advantages and disadvantages and draws comparisons between perfusion CT and magnetic resonance imaging... - Functional CT imaging in oncologyK A Miles
Wesley Research Institute, 2nd Floor Day Care Centre, The Wesley Hospital, Brisbane, Australia
Eur Radiol 13:M134-8. 2003..By simultaneously assessing tumour vascularity and metabolic demand, the broader expansion of integrated MDCT/PET imaging will support highly sophisticated assessments of tumour biology within a single examination... - Acute cerebral stroke imaging and brain perfusion with the use of high-concentration contrast mediaK A Miles
Wesley Research Institute, 2nd Floor Day Care Centre, The Wesley Hospital, Brisbane, Australia
Eur Radiol 13:M117-20. 2003..Perfusion CT offers a powerful adjunct to MDCT based imaging of cerebrovascular disease, but further clinical validation is required... - Molecular imaging with dynamic contrast-enhanced computed tomographyK A Miles
Clinical Imaging Sciences Centre, Brighton and Sussex Medical School, University of Sussex, Falmer, Brighton, UK
Clin Radiol 65:549-56. 2010..Hence, DCE-CT represents a molecular imaging technique that is applicable in clinical practice today... - Double vision: an exploration of radiologists' and general practitioners' views on using picture archiving and communication systems (PACS)Leslie Carlin
Division of Primary Care and Public Health, Brighton and Sussex Medical School, UK
Health Informatics J 16:75-86. 2010..This study highlights both impediments and pathways to the implementation of PACS in primary care, and illustrates the importance of regarding PACS as socially embedded and users as culturally disparate... - Perfusion CT for the assessment of tumour vascularity: which protocol?K A Miles
Division of Clinical and Laboratory Investigation, Brighton and Sussex Medical School, University of Sussex, Falmer, Brighton BN1 9PX, UK
Br J Radiol 76:S36-42. 2003..This article discusses the advantages and disadvantages of the more common CT perfusion protocols and offers proposals that could allow for easier comparison between studies employing different techniques... - Computed tomography perfusion imaging in acute strokeC J Keith
Southern X ray Clinics, School of Physical Sciences, Queensland University of Technology, Brisbane, Australia
Australas Radiol 46:221-30. 2002.... - Measurements of heterogeneity in gliomas on computed tomography relationship to tumour gradeKaroline Skogen
Brighton and Sussex Medical School, Brighton, UK
J Neurooncol 111:213-9. 2013..By quantifying tumour heterogeneity, CTTA has the potential to provide a marker of tumour grade for patients with cerebral glioma. By differentiating between high and low grade tumours, CTTA could possibly assist clinical management... - Tumour heterogeneity in non-small cell lung carcinoma assessed by CT texture analysis: a potential marker of survivalBalaji Ganeshan
Clinical Imaging Sciences Centre, Division of Clinical and Laboratory Investigation, Brighton and Sussex Medical School, Brighton, East Sussex, BN1 9RR, UK
Eur Radiol 22:796-802. 2012..To establish the potential for tumour heterogeneity in non-small cell lung cancer (NSCLC) as assessed by CT texture analysis (CTTA) to provide an independent marker of survival for patients with NSCLC... - Solitary pulmonary nodules: impact of quantitative contrast-enhanced CT on the cost-effectiveness of FDG-PETL A Comber
Southern X-ray Clinics, The Wesley Hospital, Auchenflower, Queensland, Australia
Clin Radiol 58:706-11. 2003..Whether QECT is used alone or in combination with PET will depend upon local availability and regional values for prior probability of malignancy within SPNs and the cost of PET relative to surgery... - An approach to demonstrating cost-effectiveness of diagnostic imaging modalities in Australia illustrated by positron emission tomographyK A Miles
Wesley PET Centre and Southern X ray Clinics, Wesley Hospital, Auchenflower, Brisbane, Queensland, Australia
Australas Radiol 45:9-18. 2001..Decision tree sensitivity analysis can demonstrate the cost-effectiveness of diagnostic imaging modalities in Australia and provides indications that PET is cost-effective for a range of clinical indications... - Functional computed tomography in oncologyK A Miles
Southernex Imaging and Queensland University of Technology, Department of Radiology, The Wesley Hospital, Chasely Street, Auchenflower, Australia
Eur J Cancer 38:2079-84. 2002..With the recent commercial availability of appropriate software and the development of multislice CT systems, functional CT is poised to make a significant impact upon the imaging of patients with cancer... - Heterogeneity of focal breast lesions and surrounding tissue assessed by mammographic texture analysis: preliminary evidence of an association with tumor invasion and estrogen receptor statusBalaji Ganeshan
Clinical and Laboratory Investigation, Clinical Imaging Sciences Centre, University of Sussex Brighton, UK
Front Oncol 1:33. 2011..The technique warrants further investigation as a possible adjunct to existing computer aided diagnosis systems... - Hepatic entropy and uniformity: additional parameters that can potentially increase the effectiveness of contrast enhancement during abdominal CTB Ganeshan
Department of Engineering and Design, University of Sussex, Brighton, UK
Clin Radiol 62:761-8. 2007.... - Pancreatic cancer: preliminary experience with sodium iodide fluorodeoxyglucose positron emission tomography in AustraliaC J Keith
Southern X-ray Clinics, The Wesley Hospital, Auchenflower, Queensland, Australia
Australas Radiol 47:17-21. 2003..Sodium iodide FDG-PET is useful in the diagnosis of pancreatic cancer, particularly in the presence of a previously detected mass... - Hepatic haemodynamics: interrelationships between contrast enhancement and perfusion on CT and Doppler perfusion indicesM A Fuentes
Southern X-ray Clinics, 2nd Floor, Day Centre, The Wesley Hospital, 451 Coronation Drive, Auchenflower, Queensland 4066, Australia
Br J Radiol 75:17-23. 2002..Increased arterial enhancement, perfusion or flow are valuable additional radiological signs for the presence of hepatic metastases that can be elicited by incorporating any one of these methods into existing imaging protocols... - In search of biologic correlates for liver texture on portal-phase CTBalaji Ganeshan
Department of Engineering and Design, University of Sussex, Brighton BN1 9QT, England, UK
Acad Radiol 14:1058-68. 2007..This study aims to identify biologic correlates for computed tomography (CT) liver texture in a series of patients with colorectal cancer... - Staging of non-small-cell lung cancer with integrated PET and CTKenneth A Miles
N Engl J Med 349:1188-90; author reply 1188-90. 2003 - Hepatic enhancement in colorectal cancer: texture analysis correlates with hepatic hemodynamics and patient survivalBalaji Ganeshan
Department of Engineering and Design, University of Sussex, Brighton BN1 9QT, UK
Acad Radiol 14:1520-30. 2007.... - Three-dimensional selective-scale texture analysis of computed tomography pulmonary angiogramsBalaji Ganeshan
Department of Engineering and Design, University of Sussex, Falmer, Brighton, England, United Kingdom
Invest Radiol 43:382-94. 2008....