K R Brain
- The role of menthol in skin penetration from topical formulations of ibuprofen 5% in vivoK R Brain
An eX Analytical Services Ltd, Cardiff University, UK
Skin Pharmacol Physiol 19:17-21. 2006..In clinical use, these products deliver comparable amounts of ibuprofen, but only Deep Reliefgel provides the secondary immediate benefit of the direct analgesic action of menthol...
- Percutaneous penetration of diethanolamine through human skin in vitro: application from cosmetic vehiclesK R Brain
An eX Analytical Services Ltd, Redwood Building, Cardiff CF10 3XF, UK
Food Chem Toxicol 43:681-90. 2005..These data provide a basis for the estimation of the potential systemic exposure and safety margins for DEA in representative cosmetic formulations...
- Content variability of active drug substance in compounded oral 3,4-diaminopyridine productsD M Green
An eX Analytical Services Ltd, Capital Business Park, Cardiff, UK
J Clin Pharm Ther 37:53-7. 2012..The objective of this study was to evaluate the variability in dosage form weight, active content variability and impurity of compounded oral 3,4-DAP drug products...
- In-vitro human skin penetration of the fragrance material geranyl nitrileK R Brain
An eX, Redwood Building, Cardiff, CF10 3XF, UK
Toxicol In Vitro 21:133-8. 2007..72+/-0.32%. Systemic exposure resulting from the use of GN as a fragrance ingredient, under unoccluded conditions, would be low based on the currently reported use levels...