K R Brain

Summary

Country: UK

Publications

  1. ncbi The role of menthol in skin penetration from topical formulations of ibuprofen 5% in vivo
    K R Brain
    An eX Analytical Services Ltd, Cardiff University, UK
    Skin Pharmacol Physiol 19:17-21. 2006
  2. ncbi Percutaneous penetration of diethanolamine through human skin in vitro: application from cosmetic vehicles
    K R Brain
    An-eX Analytical Services Ltd, Redwood Building, Cardiff CF10 3XF, UK
    Food Chem Toxicol 43:681-90. 2005
  3. ncbi In-vitro human skin penetration of the fragrance material geranyl nitrile
    K R Brain
    An eX, Redwood Building, Cardiff, CF10 3XF, UK
    Toxicol In Vitro 21:133-8. 2007

Collaborators

Detail Information

Publications3

  1. ncbi The role of menthol in skin penetration from topical formulations of ibuprofen 5% in vivo
    K R Brain
    An eX Analytical Services Ltd, Cardiff University, UK
    Skin Pharmacol Physiol 19:17-21. 2006
    ..In clinical use, these products deliver comparable amounts of ibuprofen, but only Deep Reliefgel provides the secondary immediate benefit of the direct analgesic action of menthol...
  2. ncbi Percutaneous penetration of diethanolamine through human skin in vitro: application from cosmetic vehicles
    K R Brain
    An-eX Analytical Services Ltd, Redwood Building, Cardiff CF10 3XF, UK
    Food Chem Toxicol 43:681-90. 2005
    ..These data provide a basis for the estimation of the potential systemic exposure and safety margins for DEA in representative cosmetic formulations...
  3. ncbi In-vitro human skin penetration of the fragrance material geranyl nitrile
    K R Brain
    An eX, Redwood Building, Cardiff, CF10 3XF, UK
    Toxicol In Vitro 21:133-8. 2007
    ..72+/-0.32%. Systemic exposure resulting from the use of GN as a fragrance ingredient, under unoccluded conditions, would be low based on the currently reported use levels...