Stephen Taylor

Summary

Affiliation: Birmingham Heartlands Hospital
Country: UK

Publications

  1. ncbi Lopinavir/ritonavir single agent therapy as a universal combination antiretroviral therapy stopping strategy: results from the STOP 1 and STOP 2 studies
    Stephen Taylor
    Department of Sexual Health and HIV Medicine, Directorate of Infection, Birmingham Heartlands Hospital, Birmingham, UK
    J Antimicrob Chemother 67:675-80. 2012
  2. ncbi Using HIV resistance tests in clinical practice
    Stephen Taylor
    Directorate of Sexual Medicine and HIV, Birmingham Heartlands Hospital, Heart of England NHS Foundation Trust, Birmingham, UK
    J Antimicrob Chemother 64:218-22. 2009
  3. ncbi Antiretroviral drug concentrations in the male and female genital tract: implications for the sexual transmission of HIV
    Stephen Taylor
    Department of Sexual Health and HIV Medicine, Directorate of Infection, Birmingham Heartlands Hospital, Heart of England NHS Foundation Trust, University of Birmingham, Birmingham, UK
    Curr Opin HIV AIDS 5:335-43. 2010
  4. ncbi Drug-resistant HIV-1 in the semen of men receiving antiretroviral therapy with acute sexually transmitted infections
    Stephen Taylor
    HPA Antiviral Susceptibility Reference Unit, Division of Immunity and Infection, University of Birmingham, UK
    Antivir Ther 8:479-83. 2003
  5. ncbi Lopinavir/ritonavir combined with twice-daily 400 mg indinavir: pharmacokinetics and pharmacodynamics in blood, CSF and semen
    Adil Isaac
    Hawthorne House, Department of Genitourinary Medicine, Birmingham Heartlands Hospital, Birmingham B9 5SS, UK
    J Antimicrob Chemother 54:498-502. 2004
  6. ncbi Stopping antiretroviral therapy
    Stephen Taylor
    Directorate of Sexual Medicine and HIV, Birmingham Heartlands Hospital, Heart of England NHS Foundation Trust, Bordesly Green East, Birmingham, UK
    AIDS 21:1673-82. 2007
  7. ncbi Identification of a transmission chain of HIV type 1 containing drug resistance-associated mutations
    Stephen Taylor
    Public Health Laboratory Service Antiviral Susceptibility Reference Unit, Division of Immunity and Infection, University of Birmingham, Birmingham B9 5SS, UK
    AIDS Res Hum Retroviruses 19:353-61. 2003
  8. ncbi Darunavir concentrations exceed the protein-corrected EC₅₀ for wild-type HIV in the semen of HIV-1-infected men
    Stephen Taylor
    Department of Sexual Health and HIV Medicine, Directorate of Infection, Birmingham Heartlands Hospital, Birmingham, UK
    AIDS 24:2583-7. 2010
  9. ncbi Minimal variation in T-20 binding domain of different HIV-1 subtypes from antiretroviral-naive and -experienced patients
    Li Xu
    PHLS Antiviral Susceptibility Unit, Division of Immunity and Infection, University of Birmingham Medical School, Birmingham, UK
    AIDS 16:1684-6. 2002

Detail Information

Publications9

  1. ncbi Lopinavir/ritonavir single agent therapy as a universal combination antiretroviral therapy stopping strategy: results from the STOP 1 and STOP 2 studies
    Stephen Taylor
    Department of Sexual Health and HIV Medicine, Directorate of Infection, Birmingham Heartlands Hospital, Birmingham, UK
    J Antimicrob Chemother 67:675-80. 2012
    ....
  2. ncbi Using HIV resistance tests in clinical practice
    Stephen Taylor
    Directorate of Sexual Medicine and HIV, Birmingham Heartlands Hospital, Heart of England NHS Foundation Trust, Birmingham, UK
    J Antimicrob Chemother 64:218-22. 2009
    ..In this article we discuss some 'real-life' clinical situations and aim to provide a useful insight into when and where genotypic resistance testing can be optimally applied in the management of HIV-positive adults...
  3. ncbi Antiretroviral drug concentrations in the male and female genital tract: implications for the sexual transmission of HIV
    Stephen Taylor
    Department of Sexual Health and HIV Medicine, Directorate of Infection, Birmingham Heartlands Hospital, Heart of England NHS Foundation Trust, University of Birmingham, Birmingham, UK
    Curr Opin HIV AIDS 5:335-43. 2010
    ..To summarize the recent literature (2008-2010) on antiretroviral (ARV) drug disposition into the male and female genital tract...
  4. ncbi Drug-resistant HIV-1 in the semen of men receiving antiretroviral therapy with acute sexually transmitted infections
    Stephen Taylor
    HPA Antiviral Susceptibility Reference Unit, Division of Immunity and Infection, University of Birmingham, UK
    Antivir Ther 8:479-83. 2003
    ..We conclude that in the presence of suboptimal ART, sexually transmitted infections may enhance the spread of drug-resistant HIV-1...
  5. ncbi Lopinavir/ritonavir combined with twice-daily 400 mg indinavir: pharmacokinetics and pharmacodynamics in blood, CSF and semen
    Adil Isaac
    Hawthorne House, Department of Genitourinary Medicine, Birmingham Heartlands Hospital, Birmingham B9 5SS, UK
    J Antimicrob Chemother 54:498-502. 2004
    ..To evaluate the steady-state blood plasma (BP), CSF and seminal plasma (SP) pharmacokinetics (PK) of twice-daily indinavir 400 mg and lopinavir/ritonavir...
  6. ncbi Stopping antiretroviral therapy
    Stephen Taylor
    Directorate of Sexual Medicine and HIV, Birmingham Heartlands Hospital, Heart of England NHS Foundation Trust, Bordesly Green East, Birmingham, UK
    AIDS 21:1673-82. 2007
  7. ncbi Identification of a transmission chain of HIV type 1 containing drug resistance-associated mutations
    Stephen Taylor
    Public Health Laboratory Service Antiviral Susceptibility Reference Unit, Division of Immunity and Infection, University of Birmingham, Birmingham B9 5SS, UK
    AIDS Res Hum Retroviruses 19:353-61. 2003
    ..We provide "proof of principle" that such mutations can therefore become "fixed" within the circulating virus pool...
  8. ncbi Darunavir concentrations exceed the protein-corrected EC₅₀ for wild-type HIV in the semen of HIV-1-infected men
    Stephen Taylor
    Department of Sexual Health and HIV Medicine, Directorate of Infection, Birmingham Heartlands Hospital, Birmingham, UK
    AIDS 24:2583-7. 2010
    ..Darunavir in seminal plasma were approximately 10-20% of that achieved in blood at matched time points postdrug ingestion. All seminal plasma darunavir were above the protein-corrected EC₅₀ values for wild-type HIV-1...
  9. ncbi Minimal variation in T-20 binding domain of different HIV-1 subtypes from antiretroviral-naive and -experienced patients
    Li Xu
    PHLS Antiviral Susceptibility Unit, Division of Immunity and Infection, University of Birmingham Medical School, Birmingham, UK
    AIDS 16:1684-6. 2002
    ..Minimal variation in the HR-1 region of gp41 was observed, especially within the region responsible for T-20 resistance. Any subtype differences in T-20 susceptibility do not appear to be related to HR-1 genetic variation...