D Fleming

Summary

Affiliation: Birmingham Research Unit of the Royal College of General Practitioners
Country: UK

Publications

  1. ncbi Ten lessons for the next influenza pandemic-an English perspective: a personal reflection based on community surveillance data
    Douglas M Fleming
    Royal College of General Practitioners, Research and Surveillance Centre, Birmingham, UK
    Hum Vaccin Immunother 8:138-45. 2012
  2. ncbi Surveillance recommendations based on an exploratory analysis of respiratory syncytial virus reports derived from the European Influenza Surveillance System
    Tamara J Meerhoff
    Netherlands Institute for Health Services Research NIVEL, EISS Coordination Centre, Utrecht, The Netherlands
    BMC Infect Dis 6:128. 2006
  3. ncbi The state of play in the battle against antimicrobial resistance: a general practitioner perspective
    Douglas M Fleming
    Birmingham Research Unit of the Royal College of General Practitioners, Lordswood House, 54 Lordswood Road, Harborne, Birmingham B17 9DB, UK
    J Antimicrob Chemother 60:i49-52. 2007
  4. ncbi The consistency of shingles and its significance for health monitoring
    Douglas M Fleming
    Royal College of General Practitioners, Harborne, Birmingham, UK
    Eur J Epidemiol 19:1113-8. 2004
  5. ncbi Influenza and its relationship to circulatory disorders
    D M Fleming
    Birmingham Research Unit of the Royal College of General Practitioners, Harborne, Birmingham, UK
    Epidemiol Infect 133:255-62. 2005
  6. ncbi Respiratory illness associated with influenza and respiratory syncytial virus infection
    D M Fleming
    Birmingham Research Unit of the Royal College of General Practitioners, Birmingham, UK
    Arch Dis Child 90:741-6. 2005
  7. ncbi The impact of influenza on the health and health care utilisation of elderly people
    Douglas M Fleming
    Birmingham Research Unit of the Royal College of General Practitioners, Lordswood House, 54 Lordswood Road, Harborne, Birmingham B17 9DB, UK
    Vaccine 23:S1-9. 2005
  8. ncbi Mortality in children from influenza and respiratory syncytial virus
    Douglas M Fleming
    Birmingham Research Unit of the Royal College of General Practitioners, Lordswood House, 54 Lordswood Road, Harborne, Birmingham B17 9DB, UK
    J Epidemiol Community Health 59:586-90. 2005
  9. ncbi Recent changes in the prevalence of diseases presenting for health care
    Douglas M Fleming
    Birmingham Research Unit of the Royal College of General Practitioners, Birmingham, UK
    Br J Gen Pract 55:589-95. 2005
  10. ncbi Influenza pandemics and avian flu
    Douglas Fleming
    BMJ 331:1066-9. 2005

Collaborators

Detail Information

Publications48

  1. ncbi Ten lessons for the next influenza pandemic-an English perspective: a personal reflection based on community surveillance data
    Douglas M Fleming
    Royal College of General Practitioners, Research and Surveillance Centre, Birmingham, UK
    Hum Vaccin Immunother 8:138-45. 2012
    ..10) Acceptance by the public and by health professionals of influenza vaccination as the major plank on which the impact of influenza is controlled has still not been achieved...
  2. ncbi Surveillance recommendations based on an exploratory analysis of respiratory syncytial virus reports derived from the European Influenza Surveillance System
    Tamara J Meerhoff
    Netherlands Institute for Health Services Research NIVEL, EISS Coordination Centre, Utrecht, The Netherlands
    BMC Infect Dis 6:128. 2006
    ..In this study, we assessed whether data on RSV collected by the European Influenza Surveillance Scheme (EISS) could be used to build an RSV surveillance system in Europe...
  3. ncbi The state of play in the battle against antimicrobial resistance: a general practitioner perspective
    Douglas M Fleming
    Birmingham Research Unit of the Royal College of General Practitioners, Lordswood House, 54 Lordswood Road, Harborne, Birmingham B17 9DB, UK
    J Antimicrob Chemother 60:i49-52. 2007
    ..A large gap remains between the scientific appreciation of the risks from antimicrobial resistance and effective means to measure it and thereby hopefully control it...
  4. ncbi The consistency of shingles and its significance for health monitoring
    Douglas M Fleming
    Royal College of General Practitioners, Harborne, Birmingham, UK
    Eur J Epidemiol 19:1113-8. 2004
    ..Routine monitoring of shingles in sentinel practice networks is commended as a method of assuring recording quality and as a means of estimating the survey population where the registered population is not known...
  5. ncbi Influenza and its relationship to circulatory disorders
    D M Fleming
    Birmingham Research Unit of the Royal College of General Practitioners, Harborne, Birmingham, UK
    Epidemiol Infect 133:255-62. 2005
    ..Influenza contingency planning needs to take account of these deaths in determining policy for prophylaxis and in providing facilities for cardio-respiratory resuscitation...
  6. ncbi Respiratory illness associated with influenza and respiratory syncytial virus infection
    D M Fleming
    Birmingham Research Unit of the Royal College of General Practitioners, Birmingham, UK
    Arch Dis Child 90:741-6. 2005
    ..To estimate excess morbidity during periods of influenza and respiratory syncytial virus (RSV) activity...
  7. ncbi The impact of influenza on the health and health care utilisation of elderly people
    Douglas M Fleming
    Birmingham Research Unit of the Royal College of General Practitioners, Lordswood House, 54 Lordswood Road, Harborne, Birmingham B17 9DB, UK
    Vaccine 23:S1-9. 2005
    ..In this report we discuss current issues surrounding the impact of influenza on the health care utilisation of elderly people...
  8. ncbi Mortality in children from influenza and respiratory syncytial virus
    Douglas M Fleming
    Birmingham Research Unit of the Royal College of General Practitioners, Lordswood House, 54 Lordswood Road, Harborne, Birmingham B17 9DB, UK
    J Epidemiol Community Health 59:586-90. 2005
    ..To quantify mortality attributable to influenza and respiratory syncytial virus (RSV) infection in children...
  9. ncbi Recent changes in the prevalence of diseases presenting for health care
    Douglas M Fleming
    Birmingham Research Unit of the Royal College of General Practitioners, Birmingham, UK
    Br J Gen Pract 55:589-95. 2005
    ..Practice-based morbidity surveys inform on the prevalence of diseases presenting for health care. The last major survey in England and Wales was conducted in 1991...
  10. ncbi Influenza pandemics and avian flu
    Douglas Fleming
    BMJ 331:1066-9. 2005
  11. ncbi The management of acute bronchitis in children
    Douglas M Fleming
    Birmingham Research Unit of the Royal College of General Practitioners, Lordswood House, 54 Lordswood Road, Harborne, Birmingham B17 9DB, UK
    Expert Opin Pharmacother 8:415-26. 2007
    ..This article covers a range of issues surrounding acute bronchitis, including epidemiology and pathogenesis, as well as the management, prevention and treatment of disease in children...
  12. ncbi Estimating the risk population in relation to influenza vaccination policy
    Douglas M Fleming
    Birmingham Research Unit of the Royal College of General Practitioners, Lordswood House, 54 Lordswood Road, Harborne, Birmingham B17 9DB, UK
    Vaccine 24:4378-85. 2006
    ..A set of morbidity codes is recommended which taken together include 3.2% of age group 0-14 years, 7.5% of 15-44 years and 16.6% of 45-64 years...
  13. ncbi Morbidity profiles of patients consulting during influenza and respiratory syncytial virus active periods
    D M Fleming
    Birmingham Research Unit of the Royal College of General Practitioners, Birmingham, UK
    Epidemiol Infect 135:1099-108. 2007
    ..The clinical burden of disease associated with RSV is as great if not greater than influenza in patients of all ages presenting to general practitioners...
  14. ncbi Surveillance of the bioterrorist threat: a primary care response
    D M Fleming
    Birmingham Research Unit, Royal College of General Practitioners, Lordswood House, 54 Lordswood Road, Harborne, Birmingham B17 9DB
    Commun Dis Public Health 7:68-72. 2004
    ..For the other two conditions no unusual peaks of incidence were observed in any region. Operational research based on disciplined recording of morbidity in general practice can deliver timely surveillance data on bioterrorist threats...
  15. ncbi The prevalence of known diabetes in eight European countries
    D M Fleming
    NIVEL Institute, Utrecht, The Netherlands
    Eur J Public Health 14:10-4. 2004
    ..The prevalence of diabetes known to general practitioners (GPs) in different European countries has been investigated and the usefulness of sentinel practice networks in delivering prevalence data on diabetes has been evaluated...
  16. ncbi An assessment of the effect of statin use on the incidence of acute respiratory infections in England during winters 1998-1999 to 2005-2006
    D M Fleming
    Royal College of General Practitioners, Research and Surveillance Centre, Birmingham, UK
    Epidemiol Infect 138:1281-8. 2010
    ..91 (95% CI 0.85-0.98). We found no benefit in respiratory infection outcomes attributable to statin use, although uniformly higher ORs in non-vaccinated statin users might suggest synergism between statins and influenza vaccination...
  17. ncbi The clinical diagnosis of influenza
    D Fleming
    RCGP Birmingham Research Unit, Harborne, UK
    Curr Med Res Opin 18:338-41. 2002
    ..The combination of cough and fever in conditons of known local influenza virus circulation provide a useful indicator of diagnosis to guide management...
  18. ncbi Estimating influenza vaccine effectiveness using routinely collected laboratory data
    D M Fleming
    Royal College of General Practitioners Research and Surveillance Centre, Lordswood House, 54 Lordswood Road, Harborne, Birmingham B17 9DB, UK
    J Epidemiol Community Health 64:1062-7. 2010
    ..Estimation of influenza vaccine effectiveness (V/E) is needed early during influenza outbreaks in order to optimise management of influenza--a need which will be even greater in a pandemic situation...
  19. ncbi The representativeness of sentinel practice networks
    D M Fleming
    The Royal College of General Practitioners Research and Surveillance Centre, Birmingham B17 9DB, UK
    J Public Health (Oxf) 32:90-6. 2010
    ..The representativeness of practice networks is important when using the information obtained to guide health policy...
  20. ncbi Health benefits, risks, and cost-effectiveness of influenza vaccination in children
    Douglas M Fleming
    Birmingham Research Unit, Birmingham, UK
    Pediatr Infect Dis J 27:S154-8. 2008
    ..National policies based on demonstrated cost effectiveness are desirable, but these should not become a barrier to parents wishing to secure a benefit for their child or family, provided there is clear evidence of clinical efficacy...
  21. ncbi The evolution of influenza surveillance in Europe and prospects for the next 10 years
    D M Fleming
    Birmingham Research Unit of the Royal College of General Practitioners, Lordswood House, 54 Lordswood Road, Harborne, B17 9DB, Birmingham, UK
    Vaccine 21:1749-53. 2003
    ..The report advocates the EISS model of influenza surveillance, which involves the integrated collection of clinical and laboratory data in the same population using sentinel practitioners...
  22. ncbi Zanamivir in the treatment of influenza
    Douglas M Fleming
    Birmingham Research Unit of the Royal College of General Practitioners, Lordswood House, 54 Lordswood Road, Birmingham B17 9DB, UK
    Expert Opin Pharmacother 4:799-805. 2003
    ..This review reports on the introduction of zanamivir (Relenza) to the market with particular reference to experience in the UK...
  23. ncbi Lessons from 40 years' surveillance of influenza in England and Wales
    D M Fleming
    Birmingham Research Unit of the Royal College of General Practitioners, Harborne, Birmingham, UK
    Epidemiol Infect 136:866-75. 2008
    ..Increasing pressure on hospitals during epidemic periods are shown and are attributed to changing patterns of health-care delivery...
  24. ncbi Skin infections and antibiotic prescribing: a comparison of surveillance and prescribing data
    Douglas M Fleming
    Birmingham Research Unit of the Royal College of General Practitioners, Lordswood House, 54 Lordswood Road, Harborne, Birmingham, B17 9DB, UK
    Br J Gen Pract 57:569-73. 2007
    ..Reductions in the number of dispensed antibiotics and the incidence of respiratory infections presented to GPs and have been reported. Whether this trend applies to skin infections requires further investigation...
  25. ncbi Health monitoring in sentinel practice networks: the contribution of primary care
    D M Fleming
    Birmingham Research Unit, The Royal College of General Practitioners, Birmingham, UK
    Eur J Public Health 13:80-4. 2003
    ..As part of that programme we considered how primary care might contribute relevant data...
  26. ncbi The reducing incidence of respiratory tract infection and its relation to antibiotic prescribing
    Douglas M Fleming
    Birmingham Research Unit, Royal College of General Practitioners, 54 Lordswood Road, Harborne, Birmingham B17 9DB
    Br J Gen Pract 53:778-83. 2003
    ..There is good evidence of reduced prescribing of antibiotics in recent years, but the reason for this has not been established...
  27. ncbi Influenza and adult hospital admissions for respiratory conditions in England 1989-2001
    D Fleming
    Birmingham Research Unit of the Royal College of General Practitioners, 54 Lordswood Road, Harborne, Birmingham B17 9DB
    Commun Dis Public Health 6:231-7. 2003
    ..Though robust programmes of vaccination are needed, vaccination by itself will not eliminate the impact of influenza on hospital admissions in winter...
  28. ncbi The management of influenza in people of working age
    D M Fleming
    Birmingham Research Unit of the Royal College of General Practitioners, 54 Lordswood Road, Birmingham B17 9DB, UK
    Occup Med (Lond) 52:259-63. 2002
    ..Options currently available need to be directed to a wider range of people than those conventionally regarded as the target risk group...
  29. ncbi Seasonal influenza activity in Europe: declining in most countries in the West but increasing in the North-East
    J M S Arkema
    European Influenza Surveillance Scheme Co-ordination Centre, Netherlands Institute for Health Services Research (NIVEL, Utrecht, The Netherlands
    Euro Surveill 12:E070308.3. 2007
  30. ncbi Impact of NHS Direct on general practice consultations during the winter of 1999-2000: analysis of routinely collected data
    Rachel S Chapman
    Royal College of General Practitioners, Birmingham Research Unit, Harborne, Birmingham B17 9DB
    BMJ 325:1397-8. 2002
  31. ncbi Seasonal influenza beginning in Europe: report from EISS
    J M S Arkema
    European Influenza Surveillance Scheme Co-ordination Centre, Netherlands Institute for Health Services Research (NIVEL, Utrecht, The Netherlands
    Euro Surveill 12:E070125.3. 2007
  32. ncbi Acute respiratory infections and winter pressures on hospital admissions in England and Wales 1990-2005
    Alex J Elliot
    Birmingham Research Unit of Royal College of General Practitioners, Lordswood House, 54 Lordswood Road, Harborne, Birmingham B17 9DB, UK
    J Public Health (Oxf) 30:91-8. 2008
    ..Hospitals experience winter surges in admissions due to respiratory infections. The roles of acute bronchitis and influenza-like illness (ILI) in the timing and severity of these surges are examined over the years 1990-91 to 2004-05...
  33. ncbi Influenza and respiratory syncytial virus in the elderly
    Alex J Elliot
    Birmingham Research Unit of the Royal College of General Practitioners, Lordswood House, 54 Lordswood Road, Harborne, Birmingham B17 9DB, UK
    Expert Rev Vaccines 7:249-58. 2008
    ..We discuss the potential benefit of influenza vaccination on these outcomes, including the recent controversial debate over the effectiveness of influenza vaccination...
  34. ncbi The association between impetigo, insect bites and air temperature: a retrospective 5-year study (1999-2003) using morbidity data collected from a sentinel general practice network database
    Alex J Elliot
    Birmingham Research Unit of the Royal College of General Practitioners, Harborne, Birmingham, UK
    Fam Pract 23:490-6. 2006
    ..Insect bites are commonly implicated in the development of impetigo. There are, however, very few data available to describe the seasonal incidences and association between the two conditions...
  35. ncbi Information from primary care: its importance and value. A comparison of information from Slovenia and England and Wales, viewed from the 'Health 21' perspective
    Douglas M Fleming
    Birmingham Research Unit, Royal College of General Practitioners, Birmingham, England
    Eur J Public Health 12:249-53. 2002
    ..CONCLUSIONS: Data gathered systematically from the surveillance of consultations in primary care are important to the measurement of WHO 'Health 21' targets...
  36. ncbi The incidence of shingles and its implications for vaccination policy
    Rachel S Chapman
    Birmingham Research Unit of the Royal College of General Practitioners, Lordswood House, 54 Lordswood Road, Harborne, Birmingham B17 9DB, UK
    Vaccine 21:2541-7. 2003
    ....
  37. ncbi European primary care surveillance networks: their structure and operation
    Joan G M Deckers
    Netherlands Institute for Health Services Research, Utrecht, The Netherlands, and Royal College of General Practitioners, Birmingham Research Unit, Birmingham, UK
    Fam Pract 23:151-8. 2006
    ..When fulfilling identical minimal criteria they can provide comparable estimates of morbidity, ultimately leading to improved national and European surveillance...
  38. ncbi Research opportunity in primary care
    Douglas M Fleming
    Birmingham Research Unit, Royal College of General Practitioners, Harborne, Birmingham, UK
    Scand J Prim Health Care Suppl 20:6-13. 2002
  39. ncbi WHO diagnostic criteria as a validation tool for the diagnosis of diabetes mellitus: a study in five European countries
    Joan G M Deckers
    NIVEL - Netherlands Institute for Health Services Research, Utrecht, The Netherlands
    Eur J Gen Pract 12:108-13. 2006
    ..Furthermore, we show that these diagnoses are comparable between countries. Therefore, information from general practice registration networks is a valuable and valid source for international comparisons...
  40. ncbi Differences in treatment regimes, consultation frequency and referral patterns of diabetes mellitus in general practice in five European countries
    Ge A Donker
    NIVEL Netherlands Institute for Health Services Research, Utrecht, The Netherlands
    Fam Pract 21:364-9. 2004
    ..In many European countries, maturity onset diabetes mellitus (DM) is to a large extent managed in general practice...
  41. ncbi A downturn in the incidence of head lice infestation?
    Anthony M R Downs
    Int J Dermatol 46:660-1. 2007
  42. ncbi Using electronic medical records for research
    Douglas M Fleming
    Eur J Gen Pract 11:2-4. 2005
  43. ncbi Viral infections and acute otitis media in young children
    Alex J Elliot
    Clin Infect Dis 47:146-7. 2008
  44. ncbi Safety, efficacy, and effectiveness of cold-adapted influenza vaccine-trivalent against community-acquired, culture-confirmed influenza in young children attending day care
    Timo Vesikari
    Tampere University Medical School FM3, Biokatu 10, 33520 Tampere, Finland
    Pediatrics 118:2298-312. 2006
    ....
  45. ncbi Changing disease incidence: the consulting room perspective
    Douglas M Fleming
    Br J Gen Pract 56:820-4. 2006
  46. ncbi Zanamivir prophylaxis: an effective strategy for the prevention of influenza types A and B within households
    Arnold S Monto
    School of Public Health, Department of Epidemiology, University of Michigan, Ann Arbor 48109, USA
    J Infect Dis 186:1582-8. 2002
    ..Zanamivir was well tolerated and was effective in preventing influenza types A and B within households where the index patient was not treated...
  47. ncbi Comparison of the efficacy and safety of live attenuated cold-adapted influenza vaccine, trivalent, with trivalent inactivated influenza virus vaccine in children and adolescents with asthma
    Douglas M Fleming
    Northfield Health Centre, Birmingham, United Kingdom
    Pediatr Infect Dis J 25:860-9. 2006
    ..There was no evidence of a significant increase in adverse pulmonary outcomes for CAIV-T compared with TIV. CAIV-T had a significantly greater relative efficacy of 35% compared with TIV in this high-risk population...
  48. ncbi Chronic cough. Don't forget pertussis. .
    Andrew M Ross
    BMJ 326:1036. 2003