Research Topics
| D FlemingSummaryAffiliation: Birmingham Research Unit of the Royal College of General Practitioners Country: UK Publications
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Detail Information
Publications
Ten lessons for the next influenza pandemic-an English perspective: a personal reflection based on community surveillance dataDouglas M Fleming
Royal College of General Practitioners, Research and Surveillance Centre, Birmingham, UK
Hum Vaccin Immunother 8:138-45. 2012..10) Acceptance by the public and by health professionals of influenza vaccination as the major plank on which the impact of influenza is controlled has still not been achieved...
Surveillance recommendations based on an exploratory analysis of respiratory syncytial virus reports derived from the European Influenza Surveillance SystemTamara J Meerhoff
Netherlands Institute for Health Services Research NIVEL, EISS Coordination Centre, Utrecht, The Netherlands
BMC Infect Dis 6:128. 2006..In this study, we assessed whether data on RSV collected by the European Influenza Surveillance Scheme (EISS) could be used to build an RSV surveillance system in Europe...
The state of play in the battle against antimicrobial resistance: a general practitioner perspectiveDouglas M Fleming
Birmingham Research Unit of the Royal College of General Practitioners, Lordswood House, 54 Lordswood Road, Harborne, Birmingham B17 9DB, UK
J Antimicrob Chemother 60:i49-52. 2007..A large gap remains between the scientific appreciation of the risks from antimicrobial resistance and effective means to measure it and thereby hopefully control it...
The consistency of shingles and its significance for health monitoringDouglas M Fleming
Royal College of General Practitioners, Harborne, Birmingham, UK
Eur J Epidemiol 19:1113-8. 2004..Routine monitoring of shingles in sentinel practice networks is commended as a method of assuring recording quality and as a means of estimating the survey population where the registered population is not known...
Influenza and its relationship to circulatory disordersD M Fleming
Birmingham Research Unit of the Royal College of General Practitioners, Harborne, Birmingham, UK
Epidemiol Infect 133:255-62. 2005..Influenza contingency planning needs to take account of these deaths in determining policy for prophylaxis and in providing facilities for cardio-respiratory resuscitation...
Respiratory illness associated with influenza and respiratory syncytial virus infectionD M Fleming
Birmingham Research Unit of the Royal College of General Practitioners, Birmingham, UK
Arch Dis Child 90:741-6. 2005..To estimate excess morbidity during periods of influenza and respiratory syncytial virus (RSV) activity...
The impact of influenza on the health and health care utilisation of elderly peopleDouglas M Fleming
Birmingham Research Unit of the Royal College of General Practitioners, Lordswood House, 54 Lordswood Road, Harborne, Birmingham B17 9DB, UK
Vaccine 23:S1-9. 2005..In this report we discuss current issues surrounding the impact of influenza on the health care utilisation of elderly people...
Mortality in children from influenza and respiratory syncytial virusDouglas M Fleming
Birmingham Research Unit of the Royal College of General Practitioners, Lordswood House, 54 Lordswood Road, Harborne, Birmingham B17 9DB, UK
J Epidemiol Community Health 59:586-90. 2005..To quantify mortality attributable to influenza and respiratory syncytial virus (RSV) infection in children...
Recent changes in the prevalence of diseases presenting for health careDouglas M Fleming
Birmingham Research Unit of the Royal College of General Practitioners, Birmingham, UK
Br J Gen Pract 55:589-95. 2005..Practice-based morbidity surveys inform on the prevalence of diseases presenting for health care. The last major survey in England and Wales was conducted in 1991...
Influenza pandemics and avian fluDouglas Fleming
BMJ 331:1066-9. 2005
The management of acute bronchitis in childrenDouglas M Fleming
Birmingham Research Unit of the Royal College of General Practitioners, Lordswood House, 54 Lordswood Road, Harborne, Birmingham B17 9DB, UK
Expert Opin Pharmacother 8:415-26. 2007..This article covers a range of issues surrounding acute bronchitis, including epidemiology and pathogenesis, as well as the management, prevention and treatment of disease in children...
Estimating the risk population in relation to influenza vaccination policyDouglas M Fleming
Birmingham Research Unit of the Royal College of General Practitioners, Lordswood House, 54 Lordswood Road, Harborne, Birmingham B17 9DB, UK
Vaccine 24:4378-85. 2006..A set of morbidity codes is recommended which taken together include 3.2% of age group 0-14 years, 7.5% of 15-44 years and 16.6% of 45-64 years...
Morbidity profiles of patients consulting during influenza and respiratory syncytial virus active periodsD M Fleming
Birmingham Research Unit of the Royal College of General Practitioners, Birmingham, UK
Epidemiol Infect 135:1099-108. 2007..The clinical burden of disease associated with RSV is as great if not greater than influenza in patients of all ages presenting to general practitioners...
Surveillance of the bioterrorist threat: a primary care responseD M Fleming
Birmingham Research Unit, Royal College of General Practitioners, Lordswood House, 54 Lordswood Road, Harborne, Birmingham B17 9DB
Commun Dis Public Health 7:68-72. 2004..For the other two conditions no unusual peaks of incidence were observed in any region. Operational research based on disciplined recording of morbidity in general practice can deliver timely surveillance data on bioterrorist threats...
The prevalence of known diabetes in eight European countriesD M Fleming
NIVEL Institute, Utrecht, The Netherlands
Eur J Public Health 14:10-4. 2004..The prevalence of diabetes known to general practitioners (GPs) in different European countries has been investigated and the usefulness of sentinel practice networks in delivering prevalence data on diabetes has been evaluated...
An assessment of the effect of statin use on the incidence of acute respiratory infections in England during winters 1998-1999 to 2005-2006D M Fleming
Royal College of General Practitioners, Research and Surveillance Centre, Birmingham, UK
Epidemiol Infect 138:1281-8. 2010..91 (95% CI 0.85-0.98). We found no benefit in respiratory infection outcomes attributable to statin use, although uniformly higher ORs in non-vaccinated statin users might suggest synergism between statins and influenza vaccination...
The clinical diagnosis of influenzaD Fleming
RCGP Birmingham Research Unit, Harborne, UK
Curr Med Res Opin 18:338-41. 2002..The combination of cough and fever in conditons of known local influenza virus circulation provide a useful indicator of diagnosis to guide management...
Estimating influenza vaccine effectiveness using routinely collected laboratory dataD M Fleming
Royal College of General Practitioners Research and Surveillance Centre, Lordswood House, 54 Lordswood Road, Harborne, Birmingham B17 9DB, UK
J Epidemiol Community Health 64:1062-7. 2010..Estimation of influenza vaccine effectiveness (V/E) is needed early during influenza outbreaks in order to optimise management of influenza--a need which will be even greater in a pandemic situation...
The representativeness of sentinel practice networksD M Fleming
The Royal College of General Practitioners Research and Surveillance Centre, Birmingham B17 9DB, UK
J Public Health (Oxf) 32:90-6. 2010..The representativeness of practice networks is important when using the information obtained to guide health policy...
Health benefits, risks, and cost-effectiveness of influenza vaccination in childrenDouglas M Fleming
Birmingham Research Unit, Birmingham, UK
Pediatr Infect Dis J 27:S154-8. 2008..National policies based on demonstrated cost effectiveness are desirable, but these should not become a barrier to parents wishing to secure a benefit for their child or family, provided there is clear evidence of clinical efficacy...
The evolution of influenza surveillance in Europe and prospects for the next 10 yearsD M Fleming
Birmingham Research Unit of the Royal College of General Practitioners, Lordswood House, 54 Lordswood Road, Harborne, B17 9DB, Birmingham, UK
Vaccine 21:1749-53. 2003..The report advocates the EISS model of influenza surveillance, which involves the integrated collection of clinical and laboratory data in the same population using sentinel practitioners...
Zanamivir in the treatment of influenzaDouglas M Fleming
Birmingham Research Unit of the Royal College of General Practitioners, Lordswood House, 54 Lordswood Road, Birmingham B17 9DB, UK
Expert Opin Pharmacother 4:799-805. 2003..This review reports on the introduction of zanamivir (Relenza) to the market with particular reference to experience in the UK...
Lessons from 40 years' surveillance of influenza in England and WalesD M Fleming
Birmingham Research Unit of the Royal College of General Practitioners, Harborne, Birmingham, UK
Epidemiol Infect 136:866-75. 2008..Increasing pressure on hospitals during epidemic periods are shown and are attributed to changing patterns of health-care delivery...
Skin infections and antibiotic prescribing: a comparison of surveillance and prescribing dataDouglas M Fleming
Birmingham Research Unit of the Royal College of General Practitioners, Lordswood House, 54 Lordswood Road, Harborne, Birmingham, B17 9DB, UK
Br J Gen Pract 57:569-73. 2007..Reductions in the number of dispensed antibiotics and the incidence of respiratory infections presented to GPs and have been reported. Whether this trend applies to skin infections requires further investigation...
Health monitoring in sentinel practice networks: the contribution of primary careD M Fleming
Birmingham Research Unit, The Royal College of General Practitioners, Birmingham, UK
Eur J Public Health 13:80-4. 2003..As part of that programme we considered how primary care might contribute relevant data...
The reducing incidence of respiratory tract infection and its relation to antibiotic prescribingDouglas M Fleming
Birmingham Research Unit, Royal College of General Practitioners, 54 Lordswood Road, Harborne, Birmingham B17 9DB
Br J Gen Pract 53:778-83. 2003..There is good evidence of reduced prescribing of antibiotics in recent years, but the reason for this has not been established...
Influenza and adult hospital admissions for respiratory conditions in England 1989-2001D Fleming
Birmingham Research Unit of the Royal College of General Practitioners, 54 Lordswood Road, Harborne, Birmingham B17 9DB
Commun Dis Public Health 6:231-7. 2003..Though robust programmes of vaccination are needed, vaccination by itself will not eliminate the impact of influenza on hospital admissions in winter...
The management of influenza in people of working ageD M Fleming
Birmingham Research Unit of the Royal College of General Practitioners, 54 Lordswood Road, Birmingham B17 9DB, UK
Occup Med (Lond) 52:259-63. 2002..Options currently available need to be directed to a wider range of people than those conventionally regarded as the target risk group...
Seasonal influenza activity in Europe: declining in most countries in the West but increasing in the North-EastJ M S Arkema
European Influenza Surveillance Scheme Co-ordination Centre, Netherlands Institute for Health Services Research (NIVEL, Utrecht, The Netherlands
Euro Surveill 12:E070308.3. 2007
Impact of NHS Direct on general practice consultations during the winter of 1999-2000: analysis of routinely collected dataRachel S Chapman
Royal College of General Practitioners, Birmingham Research Unit, Harborne, Birmingham B17 9DB
BMJ 325:1397-8. 2002
Seasonal influenza beginning in Europe: report from EISSJ M S Arkema
European Influenza Surveillance Scheme Co-ordination Centre, Netherlands Institute for Health Services Research (NIVEL, Utrecht, The Netherlands
Euro Surveill 12:E070125.3. 2007
Acute respiratory infections and winter pressures on hospital admissions in England and Wales 1990-2005Alex J Elliot
Birmingham Research Unit of Royal College of General Practitioners, Lordswood House, 54 Lordswood Road, Harborne, Birmingham B17 9DB, UK
J Public Health (Oxf) 30:91-8. 2008..Hospitals experience winter surges in admissions due to respiratory infections. The roles of acute bronchitis and influenza-like illness (ILI) in the timing and severity of these surges are examined over the years 1990-91 to 2004-05...
Influenza and respiratory syncytial virus in the elderlyAlex J Elliot
Birmingham Research Unit of the Royal College of General Practitioners, Lordswood House, 54 Lordswood Road, Harborne, Birmingham B17 9DB, UK
Expert Rev Vaccines 7:249-58. 2008..We discuss the potential benefit of influenza vaccination on these outcomes, including the recent controversial debate over the effectiveness of influenza vaccination...
The association between impetigo, insect bites and air temperature: a retrospective 5-year study (1999-2003) using morbidity data collected from a sentinel general practice network databaseAlex J Elliot
Birmingham Research Unit of the Royal College of General Practitioners, Harborne, Birmingham, UK
Fam Pract 23:490-6. 2006..Insect bites are commonly implicated in the development of impetigo. There are, however, very few data available to describe the seasonal incidences and association between the two conditions...
Information from primary care: its importance and value. A comparison of information from Slovenia and England and Wales, viewed from the 'Health 21' perspectiveDouglas M Fleming
Birmingham Research Unit, Royal College of General Practitioners, Birmingham, England
Eur J Public Health 12:249-53. 2002..CONCLUSIONS: Data gathered systematically from the surveillance of consultations in primary care are important to the measurement of WHO 'Health 21' targets...
The incidence of shingles and its implications for vaccination policyRachel S Chapman
Birmingham Research Unit of the Royal College of General Practitioners, Lordswood House, 54 Lordswood Road, Harborne, Birmingham B17 9DB, UK
Vaccine 21:2541-7. 2003....
European primary care surveillance networks: their structure and operationJoan G M Deckers
Netherlands Institute for Health Services Research, Utrecht, The Netherlands, and Royal College of General Practitioners, Birmingham Research Unit, Birmingham, UK
Fam Pract 23:151-8. 2006..When fulfilling identical minimal criteria they can provide comparable estimates of morbidity, ultimately leading to improved national and European surveillance...
Research opportunity in primary careDouglas M Fleming
Birmingham Research Unit, Royal College of General Practitioners, Harborne, Birmingham, UK
Scand J Prim Health Care Suppl 20:6-13. 2002
WHO diagnostic criteria as a validation tool for the diagnosis of diabetes mellitus: a study in five European countriesJoan G M Deckers
NIVEL - Netherlands Institute for Health Services Research, Utrecht, The Netherlands
Eur J Gen Pract 12:108-13. 2006..Furthermore, we show that these diagnoses are comparable between countries. Therefore, information from general practice registration networks is a valuable and valid source for international comparisons...
Differences in treatment regimes, consultation frequency and referral patterns of diabetes mellitus in general practice in five European countriesGe A Donker
NIVEL Netherlands Institute for Health Services Research, Utrecht, The Netherlands
Fam Pract 21:364-9. 2004..In many European countries, maturity onset diabetes mellitus (DM) is to a large extent managed in general practice...
A downturn in the incidence of head lice infestation?Anthony M R Downs
Int J Dermatol 46:660-1. 2007
Using electronic medical records for researchDouglas M Fleming
Eur J Gen Pract 11:2-4. 2005
Viral infections and acute otitis media in young childrenAlex J Elliot
Clin Infect Dis 47:146-7. 2008
Safety, efficacy, and effectiveness of cold-adapted influenza vaccine-trivalent against community-acquired, culture-confirmed influenza in young children attending day careTimo Vesikari
Tampere University Medical School FM3, Biokatu 10, 33520 Tampere, Finland
Pediatrics 118:2298-312. 2006....
Changing disease incidence: the consulting room perspectiveDouglas M Fleming
Br J Gen Pract 56:820-4. 2006
Zanamivir prophylaxis: an effective strategy for the prevention of influenza types A and B within householdsArnold S Monto
School of Public Health, Department of Epidemiology, University of Michigan, Ann Arbor 48109, USA
J Infect Dis 186:1582-8. 2002..Zanamivir was well tolerated and was effective in preventing influenza types A and B within households where the index patient was not treated...
Comparison of the efficacy and safety of live attenuated cold-adapted influenza vaccine, trivalent, with trivalent inactivated influenza virus vaccine in children and adolescents with asthmaDouglas M Fleming
Northfield Health Centre, Birmingham, United Kingdom
Pediatr Infect Dis J 25:860-9. 2006..There was no evidence of a significant increase in adverse pulmonary outcomes for CAIV-T compared with TIV. CAIV-T had a significantly greater relative efficacy of 35% compared with TIV in this high-risk population...
Chronic cough. Don't forget pertussis. . Andrew M Ross
BMJ 326:1036. 2003
