David R Bentley

Summary

Country: UK

Publications

  1. ncbi request reprint Genomes for medicine
    David R Bentley
    The Wellcome Trust Sanger Institute, Hinxton, Cambridge CB10 1SA, UK
    Nature 429:440-5. 2004
  2. pmc The DNA sequence of the human X chromosome
    Mark T Ross
    The Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SA, UK
    Nature 434:325-37. 2005
  3. ncbi request reprint Whole-genome re-sequencing
    David R Bentley
    Solexa Ltd, Chesterford Research Park, Little Chesterford, Near Saffron Walden, Essex, CB10 1XL, UK
    Curr Opin Genet Dev 16:545-52. 2006
  4. pmc Accurate whole human genome sequencing using reversible terminator chemistry
    David R Bentley
    Illumina Cambridge Ltd Formerly Solexa Ltd, Chesterford Research Park, Little Chesterford, Nr Saffron Walden, Essex CB10 1XL, UK
    Nature 456:53-9. 2008
  5. ncbi request reprint A physical map of the mouse genome
    Simon G Gregory
    The Wellcome Trust Sanger Institute, Hinxton, Cambridge CB10 1SA, UK
    Nature 418:743-50. 2002
  6. ncbi request reprint The fine-scale structure of recombination rate variation in the human genome
    Gilean A T McVean
    Department of Statistics, University of Oxford, Oxford OX1 3TG, UK
    Science 304:581-4. 2004
  7. ncbi request reprint The sequences of the human sex chromosomes
    Mark T Ross
    Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, CB10 1SA, UK
    Curr Opin Genet Dev 16:213-8. 2006
  8. pmc Genome-wide detection and characterization of positive selection in human populations
    Pardis C Sabeti
    Broad Institute of MIT and Harvard, Cambridge, Massachusetts 02139, USA
    Nature 449:913-8. 2007

Detail Information

Publications8

  1. ncbi request reprint Genomes for medicine
    David R Bentley
    The Wellcome Trust Sanger Institute, Hinxton, Cambridge CB10 1SA, UK
    Nature 429:440-5. 2004
    ..Flexible and user-friendly access to well-annotated genomes will create an environment for innovation, and the potential for unlimited use of sequencing in biomedical research and practice...
  2. pmc The DNA sequence of the human X chromosome
    Mark T Ross
    The Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SA, UK
    Nature 434:325-37. 2005
    ..Of this number, 168 have been explained by mutations in 113 X-linked genes, which in many cases were characterized with the aid of the DNA sequence...
  3. ncbi request reprint Whole-genome re-sequencing
    David R Bentley
    Solexa Ltd, Chesterford Research Park, Little Chesterford, Near Saffron Walden, Essex, CB10 1XL, UK
    Curr Opin Genet Dev 16:545-52. 2006
    ..One or more new sequencing technologies are expected to become the mainstay of future research, and to make DNA sequencing centre stage as a routine tool in genetic research in the coming years...
  4. pmc Accurate whole human genome sequencing using reversible terminator chemistry
    David R Bentley
    Illumina Cambridge Ltd Formerly Solexa Ltd, Chesterford Research Park, Little Chesterford, Nr Saffron Walden, Essex CB10 1XL, UK
    Nature 456:53-9. 2008
    ..Our approach is effective for accurate, rapid and economical whole-genome re-sequencing and many other biomedical applications...
  5. ncbi request reprint A physical map of the mouse genome
    Simon G Gregory
    The Wellcome Trust Sanger Institute, Hinxton, Cambridge CB10 1SA, UK
    Nature 418:743-50. 2002
    ..The human sequence may be used to facilitate construction of other mammalian genome maps using the same strategy...
  6. ncbi request reprint The fine-scale structure of recombination rate variation in the human genome
    Gilean A T McVean
    Department of Statistics, University of Oxford, Oxford OX1 3TG, UK
    Science 304:581-4. 2004
    ..We demonstrate that recombination hotspots are a ubiquitous feature of the human genome, occurring on average every 200 kilobases or less, but recombination occurs preferentially outside genes...
  7. ncbi request reprint The sequences of the human sex chromosomes
    Mark T Ross
    Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, CB10 1SA, UK
    Curr Opin Genet Dev 16:213-8. 2006
    ..In addition, they have been useful for identifying variants associated with simple Mendelian disorders such as microphthalmia or mental retardation, and more complex disorders such as osteoporosis...
  8. pmc Genome-wide detection and characterization of positive selection in human populations
    Pardis C Sabeti
    Broad Institute of MIT and Harvard, Cambridge, Massachusetts 02139, USA
    Nature 449:913-8. 2007
    ....