Daniel M Berney

Summary

Affiliation: Barts and The London NHS Trust
Country: UK

Publications

  1. pmc Local progression among men with conservatively treated localized prostate cancer: results from the Transatlantic Prostate Group
    James A Eastham
    Department of Urology, Memorial Sloan Kettering Cancer Center, New York, New York, USA
    Eur Urol 53:347-54. 2008
  2. doi request reprint International Society of Urological Pathology (ISUP) Consensus Conference on Handling and Staging of Radical Prostatectomy Specimens. Working group 4: seminal vesicles and lymph nodes
    Daniel M Berney
    Department of Molecular Oncology and Imaging, St Bartholomew s Hospital Queen Mary University of London, London, UK
    Mod Pathol 24:39-47. 2011
  3. doi request reprint Update on testis tumours
    Daniel M Berney
    Centre for Molecular Oncology and Department of Cellular Pathology, Queen Mary University of London, UK
    Pathology 44:419-26. 2012
  4. doi request reprint Prostate cancer: towards the standardization and synthesis of morphology, genetics, and prognosis
    Dan Berney
    Department of Medical Oncology, Barts Cancer Centre, Barts and London School of Medicine and Dentistry, London, UK
    Histopathology 60:1-3. 2012
  5. ncbi request reprint Low Gleason score prostatic adenocarcinomas are no longer viable entities
    D M Berney
    Department of Cellular Pathology, St Bartholomew s Hospital, Barts and The London, Queen Mary University School of Medicine and Dentistry, London, UK
    Histopathology 50:683-90. 2007
  6. pmc Ki-67 and outcome in clinically localised prostate cancer: analysis of conservatively treated prostate cancer patients from the Trans-Atlantic Prostate Group study
    D M Berney
    The Orchid Tissue Laboratory, Centre for Molecular Oncology, Barts and the London School of Medicine and Dentistry, London, UK
    Br J Cancer 100:888-93. 2009
  7. doi request reprint Biomarkers for prostate cancer detection and progression: Beyond prostate-specific antigen
    Daniel M Berney
    Centre for Molecular Oncology and Imaging, Barts and the London School of Medicine and Dentistry, Queen Mary University of London, London, UK
    Drug News Perspect 23:185-94. 2010
  8. ncbi request reprint The association between intratubular seminoma and invasive germ cell tumors
    Daniel M Berney
    Department of Histopathology and Morbid Anatomy, St Bartholomew s and the Royal London School of Medicine and Dentistry, Queen Mary University of London, West Smithfield, UK
    Hum Pathol 37:458-61. 2006
  9. ncbi request reprint The frequency and distribution of intratubular trophoblast in association with germ cell tumors of the testis
    Daniel M Berney
    Department of Histopathology and Morbid Anatomy, Bartholomew s and the Royal London School of Medicine and Dentistry, Queen Mary University of London, St Bartholomew s Hospital, West Smithfield, London EC1A 7BE, UK
    Am J Surg Pathol 29:1300-3. 2005
  10. doi request reprint Pathology in prostate research: optimizing the pathological data
    Daniel M Berney
    Department of Molecular Oncology and Imaging, Institute of Cancer, Queen Mary University of London, London, UK
    Acta Oncol 50:49-52. 2011

Detail Information

Publications44

  1. pmc Local progression among men with conservatively treated localized prostate cancer: results from the Transatlantic Prostate Group
    James A Eastham
    Department of Urology, Memorial Sloan Kettering Cancer Center, New York, New York, USA
    Eur Urol 53:347-54. 2008
    ..Men with clinically detected localized prostate cancer treated without curative intent are at risk of complications from local tumor growth. We investigated rates of local progression and need for local therapy among such men...
  2. doi request reprint International Society of Urological Pathology (ISUP) Consensus Conference on Handling and Staging of Radical Prostatectomy Specimens. Working group 4: seminal vesicles and lymph nodes
    Daniel M Berney
    Department of Molecular Oncology and Imaging, St Bartholomew s Hospital Queen Mary University of London, London, UK
    Mod Pathol 24:39-47. 2011
    ..These consensus decisions will hopefully clarify the difficult areas of pathological assessment in radical prostatectomy evaluation and improve the concordance of research series to allow more accurate assessment of patient prognosis...
  3. doi request reprint Update on testis tumours
    Daniel M Berney
    Centre for Molecular Oncology and Department of Cellular Pathology, Queen Mary University of London, UK
    Pathology 44:419-26. 2012
    ..New clinically important entities will also be described, as well as some pitfalls in the diagnosis of testicular tumours and how to avoid them...
  4. doi request reprint Prostate cancer: towards the standardization and synthesis of morphology, genetics, and prognosis
    Dan Berney
    Department of Medical Oncology, Barts Cancer Centre, Barts and London School of Medicine and Dentistry, London, UK
    Histopathology 60:1-3. 2012
    ..We hope that this exciting and rapidly changing field will capture the imagination of both experienced and trainee pathologists to advance the field in both research and diagnosis...
  5. ncbi request reprint Low Gleason score prostatic adenocarcinomas are no longer viable entities
    D M Berney
    Department of Cellular Pathology, St Bartholomew s Hospital, Barts and The London, Queen Mary University School of Medicine and Dentistry, London, UK
    Histopathology 50:683-90. 2007
    ..Gleason grade 2 (and therefore score 4 and 5) tumours require serious re-evaluation if they are to remain clinically useful diagnoses...
  6. pmc Ki-67 and outcome in clinically localised prostate cancer: analysis of conservatively treated prostate cancer patients from the Trans-Atlantic Prostate Group study
    D M Berney
    The Orchid Tissue Laboratory, Centre for Molecular Oncology, Barts and the London School of Medicine and Dentistry, London, UK
    Br J Cancer 100:888-93. 2009
    ..As it is already in widespread use in routine pathology, it is confirmed as the most promising biomarker to be applied into routine practice...
  7. doi request reprint Biomarkers for prostate cancer detection and progression: Beyond prostate-specific antigen
    Daniel M Berney
    Centre for Molecular Oncology and Imaging, Barts and the London School of Medicine and Dentistry, Queen Mary University of London, London, UK
    Drug News Perspect 23:185-94. 2010
    ..Dissection of the genetic basis of the disease may lead to discoveries that will enhance our understanding and aid the search for prognostically valuable biomarkers...
  8. ncbi request reprint The association between intratubular seminoma and invasive germ cell tumors
    Daniel M Berney
    Department of Histopathology and Morbid Anatomy, St Bartholomew s and the Royal London School of Medicine and Dentistry, Queen Mary University of London, West Smithfield, UK
    Hum Pathol 37:458-61. 2006
    ..However, because it is not specifically associated with seminoma, we suggest that it is not useful to discriminate this lesion from IGCNU and that it merely represents an advanced form of IGCNU on the way to invasive malignancy...
  9. ncbi request reprint The frequency and distribution of intratubular trophoblast in association with germ cell tumors of the testis
    Daniel M Berney
    Department of Histopathology and Morbid Anatomy, Bartholomew s and the Royal London School of Medicine and Dentistry, Queen Mary University of London, St Bartholomew s Hospital, West Smithfield, London EC1A 7BE, UK
    Am J Surg Pathol 29:1300-3. 2005
    ..Differentiation toward trophoblastic elements in GCTs may occur at an earlier stage of their pathogenesis than has been previously recognized...
  10. doi request reprint Pathology in prostate research: optimizing the pathological data
    Daniel M Berney
    Department of Molecular Oncology and Imaging, Institute of Cancer, Queen Mary University of London, London, UK
    Acta Oncol 50:49-52. 2011
    ..Conclusion. Appropriate utilization of such pathological material will produce improved cohorts in which it will be possible to test new biomarkers with increased rigor...
  11. ncbi request reprint The frequency of intratubular embryonal carcinoma: implications for the pathogenesis of germ cell tumours
    D M Berney
    Department of Histopathology and Morbid Anatomy, St Bartholomew s and The Royal London Hospital School of Medicine and Dentistry, St Bartholomew s Hospital, London, UK
    Histopathology 45:155-61. 2004
    ..Intratubular germ cell neoplasia of unclassified type (IGCNU) is common in NSGCT; however, IEC is rarely described...
  12. doi request reprint Pathology in prostate research: optimizing tissue quality
    Daniel M Berney
    Department of Molecular Oncology and Imaging, Institute of Cancer, Queen Mary University of London, London, UK
    Acta Oncol 50:53-5. 2011
    ..The collection of tissue from the prostate gland for research creates unique challenges in the identification of cancer and in preserving pathological material...
  13. pmc DNA topoisomerase I and II expression in drug resistant germ cell tumours
    D M Berney
    Department of Histopathology and Morbid Anatomy, St Bartholomew s Hospital, Queen Mary s School of Medicine and Dentistry, London EC1 7BE, UK
    Br J Cancer 87:624-9. 2002
    ..These results suggest that topoisomerase I inhibitors may be useful in chemorefractory germ cell tumours, especially yolk sac tumours and where there are unresectable residual teratoma, mature deposits...
  14. ncbi request reprint Loss of CD30 expression in metastatic embryonal carcinoma: the effects of chemotherapy?
    D M Berney
    Department of Histopathology and Morbid Anatomy, St Bartholomew s Hospital, London, UK
    Histopathology 39:382-5. 2001
    ..CD30 has been shown to be consistently strongly expressed in embryonal carcinomas. Our aim was to examine changes in CD30 expression in embryonal carcinomas before and after treatment with chemotherapy...
  15. ncbi request reprint Pitfalls in the diagnosis of prostatic cancer: retrospective review of 1791 cases with clinical outcome
    D M Berney
    Department of Histopathology, St Bartholomew s Hospital, London, UK
    Histopathology 51:452-7. 2007
    ..To assess the possible reasons for error in the diagnosis of prostatic cancer with available follow-up data...
  16. doi request reprint The retinoblastoma protein/p16 INK4A pathway but not p53 is disrupted by human papillomavirus in penile squamous cell carcinoma
    Elzbieta Stankiewicz
    Queen Mary University of London, Centre for Molecular Oncology and Imaging, Barts and the London School of Medicine and Dentistry, London, UK
    Histopathology 58:433-9. 2011
    ..The aim was to determine the extent of HPV infection in different histological subtypes of PSCC and its impact on the expression of key cell-cycle proteins: p53, p21, p16(INK4A) and retinoblastoma (RB) protein...
  17. pmc An improved prognostic model for stage T1a and T1b prostate cancer by assessments of cancer extent
    Ramzi Rajab
    Centre for Molecular Oncology and Imaging, Barts and the London School of Medicine and Dentistry, Queen Mary University of London, London, UK
    Mod Pathol 24:58-63. 2011
    ..Staging by a four-group subdivision would substantially improve prognostication in patients with early stage disease and also may help to refine management decisions in patients who would do well with conservative treatments...
  18. doi request reprint The prognostic value of Ki-67 expression in penile squamous cell carcinoma
    Elzbieta Stankiewicz
    Department of Molecular Oncology, Barts Cancer Institute, London, UK
    J Clin Pathol 65:534-7. 2012
    ..To determine whether Ki-67 immunoexpression in penile squamous cell carcinoma (PSCC) has a prognostic value and correlates with lymph node metastasis, human papillomavirus (HPV) infection and patient survival...
  19. pmc Measurements of cancer extent in a conservatively treated prostate cancer biopsy cohort
    Ramzi Rajab
    Centre for Molecular Oncology and Imaging, Queen Mary University of London, UK
    Virchows Arch 457:547-53. 2010
    ..The percentage of positive cores appeared the strongest predictor and was stronger than percentage length of cancer in the cores...
  20. doi request reprint High-resolution genome-wide copy-number analysis suggests a monoclonal origin of multifocal prostate cancer
    Lara K Boyd
    Centre for Molecular Oncology, Barts Cancer Institute, Queen Mary University of London, London, UK
    Genes Chromosomes Cancer 51:579-89. 2012
    ..These findings, which demonstrate the monoclonal origin of multifocal prostate cancer, should significantly enhance our understanding of prostate carcinogenesis...
  21. doi request reprint Immunohistochemistry for p16, but not Rb or p21, is an independent predictor of prognosis in conservatively treated, clinically localised prostate cancer
    Sakunthala C Kudahetti
    Centre for Molecular Oncology and Imaging, Barts and the London School of Medicine and Dentistry, Queen Mary University of London, UK
    Pathology 42:519-23. 2010
    ....
  22. pmc The association of CCND1 overexpression and cisplatin resistance in testicular germ cell tumors and other cancers
    Elodie E Noel
    Medical Oncology Centre, Cancer Institute, Barts and London School of Medicine and Dentistry, Queen Mary, University of London, Charterhouse Square, London EC1M 6BQ, UK
    Am J Pathol 176:2607-15. 2010
    ..CCND1 could be potentially used as a marker for treatment stratification and as a molecular target to improve the treatment of platinum-resistant tumors...
  23. ncbi request reprint Malignant germ cell tumours in the elderly: a histopathological review of 50 cases in men aged 60 years or over
    Daniel M Berney
    Department of Histopathology, Barts, The London School of Medicine and Dentistry, St Bartholomew s Hospital, West Smithfield, London, UK
    Mod Pathol 21:54-9. 2008
    ..We conclude that germ cell tumours, in man aged 60 years or above, present at a later stage than in younger men, and although most are seminomas, non-seminomatous tumours may occur with a wide spectrum of morphology...
  24. pmc Prognostic value of an RNA expression signature derived from cell cycle proliferation genes in patients with prostate cancer: a retrospective study
    Jack Cuzick
    Cancer Research UK Centre of Epidemiology, Mathematics and Statistics, Wolfson Institute of Preventive Medicine, St Bartholomew s Medical School, Queen Mary University of London, London, UK
    Lancet Oncol 12:245-55. 2011
    ..We assessed the prognostic value of a predefined cell cycle progression (CCP) score in two cohorts of patients with prostate cancer...
  25. pmc Absolute quantitation of DNA methylation of 28 candidate genes in prostate cancer using pyrosequencing
    Natasa Vasiljevic
    Cancer Research UK Centre for Epidemiology, Mathematics and Statistics, Wolfson Institute of Preventive Medicine, Barts and the London School of Dentistry and Medicine, Queen Mary University of London, London, UK
    Dis Markers 30:151-61. 2011
    ....
  26. doi request reprint p53 immunochemistry is an independent prognostic marker for outcome in conservatively treated prostate cancer
    Sak Kudahetti
    The Orchid Tissue Laboratory, Barts and the London School of Medicine and Dentistry, Centre for Molecular Oncology, London
    BJU Int 104:20-4. 2009
    ..03) and overall survival (HR 1.57, 95% CI 1.21-2.05, P = 0.001). CONCLUSIONS We conclude that p53 may have a role in the future assessment of newly diagnosed prostate cancer, as it significantly adds to the current prognostic model...
  27. pmc Alternative HER/PTEN/Akt pathway activation in HPV positive and negative penile carcinomas
    Elzbieta Stankiewicz
    Centre for Molecular Oncology and Imaging, Institute of Cancer, Barts and the London School of Medicine and Dentistry, Queen Mary University of London, London, United Kingdom
    PLoS ONE 6:e17517. 2011
    ..We investigated HER family receptors and phosphatase and tension homolog (PTEN) in HPV-positive and negative PSCC and its impact on Akt activation using immunohistochemistry and fluorescent in situ hybridisation (FISH)...
  28. doi request reprint HPV infection and immunochemical detection of cell-cycle markers in verrucous carcinoma of the penis
    Elzbieta Stankiewicz
    Centre for Molecular Oncology and Imaging, Barts and the London School of Medicine and Dentistry, London, UK
    Mod Pathol 22:1160-8. 2009
    ....
  29. ncbi request reprint Major shifts in the treatment and prognosis of prostate cancer due to changes in pathological diagnosis and grading
    Daniel M Berney
    Department of Histopathology, St Bartholomew s Hospital, Queen Mary University of London, London, UK
    BJU Int 100:1240-4. 2007
    ..To examine data on the changes in the accuracy of the diagnosis of prostate cancer and of Gleason grading in the modern era...
  30. pmc Androgen-induced TMPRSS2:ERG fusion in nonmalignant prostate epithelial cells
    Nuria Coll Bastus
    Centre of Molecular Oncology and Imaging, Institute of Cancer, Barts and the London School of Medicine and Dentistry, Queen Mary University of London, London, UK
    Cancer Res 70:9544-8. 2010
    ..This study demonstrates that fusions can be induced prior to malignant transformation and generation of the fusion is associated with both gene proximity and loss of the ability to prevent double-strand breaks...
  31. doi request reprint DNA topoisomerase I and IIalpha expression in penile carcinomas: assessing potential tumour chemosensitivity
    Daniel M Berney
    The Orchid Tissue Laboratory, Barts and the London School of Medicine and Dentistry, Queen Mary, University of London, London, UK
    BJU Int 102:1040-4. 2008
    ....
  32. pmc Distinct genomic alterations in prostate cancers in Chinese and Western populations suggest alternative pathways of prostate carcinogenesis
    Xueying Mao
    Molecular Oncology and Imaging Centre, Medical Oncology Centre, Institute of Cancer, Barts and the London School of Medicine and Dentistry, Queen Mary University of London, London, United Kingdom
    Cancer Res 70:5207-12. 2010
    ..Our findings suggest that tumors arise in Western and Chinese populations by alternative pathogenetic mechanisms...
  33. doi request reprint Ten testicular trapdoors
    R Rajab
    Department of Cellular Pathology, The Orchid Tissue Laboratory, Barts and The London NHS Trust, The Royal London Hospital, Whitechapel, London, UK
    Histopathology 53:728-39. 2008
    ..We therefore describe ten areas of testicular pathology which may cause diagnostic confusion for pathologists: ten testicular trapdoors...
  34. doi request reprint The reasons behind variation in Gleason grading of prostatic biopsies: areas of agreement and misconception among 266 European pathologists
    Daniel M Berney
    Queen Mary University of London, London, UK
    Histopathology 64:405-11. 2014
    ..The Gleason scoring system underwent revision at the International Society of Urological Pathology (ISUP) conference in 2005. It is not known how uropathologists have interpreted its recommendations...
  35. pmc Variations in the processing of prostatic needle cores in the UK; what is safe?
    O Biedrzycki
    Barts and the London School of Medicine and Dentistry, St Bartholomews Hospital, West Smithfield, London, EC1 7BE, UK
    J Clin Pathol 56:341-3. 2003
    ..To determine the variation in the processing of prostatic needle cores in the UK and to compare the results with suggested guidelines...
  36. pmc Prediction of progression in pTa and pT1 bladder carcinomas with p53, p16 and pRb
    A W Hitchings
    Department of Histopathology and Morbid Anatomy, Bart s and The London School of Medicine and Dentistry, St Bartholomew s Hospital, West Smithfield, London EC1A 7BE, UK
    Br J Cancer 91:552-7. 2004
    ..29 (CI 1.24-69.50). Overall, we conclude that the immunohistochemical evaluation of p53 and p16 may have independent prognostic value for disease progression, and may help guide management decisions in these tumours...
  37. doi request reprint Evidence supporting the existence of benign teratomas of the postpubertal testis: a clinical, histopathologic, and molecular genetic analysis of 25 cases
    Chen Zhang
    Department of Pathology and Laboratory Medicine, Indiana University School of Medicine, Indiana University Health Partners, Indianapolis, IN, USA
    Am J Surg Pathol 37:827-35. 2013
    ..It is important to distinguish these teratomas from the usual ones seen in postpuberal patients because of the malignant potential of the latter...
  38. pmc Prediction of relapse after lymph node dissection for germ cell tumours: can salvage chemotherapy be avoided?
    D M Berney
    Dept of Histopathology and Morbid Anantomy, Barts and The London NHS Trust, St Bartholomews Hospital, London, UK
    Br J Cancer 84:340-3. 2001
    ..Patients with such a high risk of recurrence could be considered for post-operative adjuvant therapy at this point whilst others would be suitable for a watchful waiting approach...
  39. ncbi request reprint Staging and classification of testicular tumours: pitfalls from macroscopy to diagnosis
    D M Berney
    The Orchid Tissue Laboratory, Barts and the London School of Medicine and Dentistry, St Bartholomew s Hospital, West Smithfield, London EC1A 7BE, UK
    J Clin Pathol 61:20-4. 2008
    ..From careful macroscopic examination, to accurate histological typing and reporting of adverse pathological parameters, the pathologist plays a major role in the successful treatment of a group of rare, but largely treatable, tumours...
  40. ncbi request reprint Markers of cell proliferation in a GH-producing adenoma of a patient treated with pegvisomant
    W M Drake
    Department of Endocrinology, St Bartholomew s Hospital, West Smithfield, London, UK
    Eur J Endocrinol 153:203-5. 2005
    ....
  41. pmc The identification of chromosomal translocation, t(4;6)(q22;q15), in prostate cancer
    L Shan
    Barts and the London School of Medicine and Dentistry, Queen Mary University of London, London, UK
    Prostate Cancer Prostatic Dis 13:117-25. 2010
    ..0628). The potential role of this translocation in the development of human prostate cancer is discussed...
  42. ncbi request reprint The case for modifying the Gleason grading system
    Daniel M Berney
    Department of Cellular Pathology, Barts and the London School of Medicine and Dentistry, The Royal London Hospital, London, UK
    BJU Int 100:725-6. 2007
  43. pmc Nomogram incorporating PSA level to predict cancer-specific survival for men with clinically localized prostate cancer managed without curative intent
    Michael W Kattan
    Department of Quantitative Health Sciences, Cleveland Clinic, Cleveland, Ohio, USA
    Cancer 112:69-74. 2008
    ..After collecting data on a large cohort of men who received no initial active prostate cancer therapy, the aim was to develop, and to internally validate, a nomogram for prediction of disease-specific survival...
  44. ncbi request reprint Adult leydig cell tumors of the testis caused by germline fumarate hydratase mutations
    Luis G Carvajal-Carmona
    Laboratory of Molecular and Population Genetics, London Research Institute, Cancer Research UK, London WC2A 3PX, United Kingdom
    J Clin Endocrinol Metab 91:3071-5. 2006
    ..We identified an LCT in an affected individual from a kindred with hereditary leiomyomatosis and renal cell cancer (HLRCC) and a germline fumarate hydratase (FH) mutation (N64T)...