N H Barton

Summary

Country: UK

Publications

  1. ncbi request reprint Clines in polygenic traits
    N H Barton
    Institute of Cell, Animal and Population Biology, University of Edinburgh, Scotland, UK
    Genet Res 74:223-36. 1999
  2. ncbi request reprint Estimating multilocus linkage disequilibria
    N H Barton
    Institute of Cell, Animal and Population Biology, University of Edinburgh, West Mains Road, Edinburgh EH9 3 JT, Scotland
    Heredity (Edinb) 84:373-89. 2000
  3. doi request reprint Investigating temporal changes in hybridization and introgression in a predominantly bimodal hybridizing population of invasive sika (Cervus nippon) and native red deer (C. elaphus) on the Kintyre Peninsula, Scotland
    H V Senn
    Institute of Evolutionary Biology, School of Biological Sciences, University of Edinburgh, Edinburgh, UK
    Mol Ecol 19:910-24. 2010
  4. pmc Evolution of recombination due to random drift
    N H Barton
    School of Biological Sciences, University of Edinburgh, UK
    Genetics 169:2353-70. 2005
  5. ncbi request reprint Effects of genetic drift on variance components under a general model of epistasis
    N H Barton
    Institute of Cell, Animal and Population Biology, University of Edinburgh, EH9 3JT, United Kingdom
    Evolution 58:2111-32. 2004
  6. ncbi request reprint The role of hybridization in evolution
    N H Barton
    Institute of Cell, Animal and Population Biology, University of Edinburgh, King s Buildings, Edinburgh EH9 3JT, UK
    Mol Ecol 10:551-68. 2001
  7. ncbi request reprint The stability of symmetric solutions to polygenic models
    N H Barton
    Institute of Cell, Animal and Population Biology, University of Edinburgh, West Mains Road, Edinburgh, EH9 3JT, Scotland
    Theor Popul Biol 57:249-63. 2000
  8. ncbi request reprint Why sex and recombination?
    N H Barton
    Institute of Cell, Animal and Population Biology, University of Edinburgh, West Mains Road, Edinburgh EH9 3JT, UK
    Science 281:1986-90. 1998
  9. doi request reprint On the application of statistical physics to evolutionary biology
    N H Barton
    Institute of Evolutionary Biology, School of Biological Sciences, University of Edinburgh, Kings Buildings, Edinburgh EH9 3JT, UK
    J Theor Biol 259:317-24. 2009
  10. ncbi request reprint The effect of epistasis on the structure of hybrid zones
    N H Barton
    Institute of Cell, Animal and Population Biology, University of Edinburgh, UK
    Genet Res 75:179-98. 2000

Collaborators

Detail Information

Publications18

  1. ncbi request reprint Clines in polygenic traits
    N H Barton
    Institute of Cell, Animal and Population Biology, University of Edinburgh, Scotland, UK
    Genet Res 74:223-36. 1999
    ..Linkage disequilibria can generate a substantial increase in genetic variance, which is concentrated at sharp gradients in trait means...
  2. ncbi request reprint Estimating multilocus linkage disequilibria
    N H Barton
    Institute of Cell, Animal and Population Biology, University of Edinburgh, West Mains Road, Edinburgh EH9 3 JT, Scotland
    Heredity (Edinb) 84:373-89. 2000
    ..Both methods perform well when tested against simulations with two or four loci...
  3. doi request reprint Investigating temporal changes in hybridization and introgression in a predominantly bimodal hybridizing population of invasive sika (Cervus nippon) and native red deer (C. elaphus) on the Kintyre Peninsula, Scotland
    H V Senn
    Institute of Evolutionary Biology, School of Biological Sciences, University of Edinburgh, Edinburgh, UK
    Mol Ecol 19:910-24. 2010
    ..Although we demonstrate that low rates of F1 hybridization can lead to substantial introgression, the progress of hybridization and introgression appears to be unpredictable over the short timescales...
  4. pmc Evolution of recombination due to random drift
    N H Barton
    School of Biological Sciences, University of Edinburgh, UK
    Genetics 169:2353-70. 2005
    ..Selection for a modifier that increases recombination is highest when linkage among loci is tight, when beneficial alleles rise from low to high frequency, and when the population size is small...
  5. ncbi request reprint Effects of genetic drift on variance components under a general model of epistasis
    N H Barton
    Institute of Cell, Animal and Population Biology, University of Edinburgh, EH9 3JT, United Kingdom
    Evolution 58:2111-32. 2004
    ..Although our analyses clarify the conditions under which drift is expected to increase V(A), we question the evolutionary importance of such increases...
  6. ncbi request reprint The role of hybridization in evolution
    N H Barton
    Institute of Cell, Animal and Population Biology, University of Edinburgh, King s Buildings, Edinburgh EH9 3JT, UK
    Mol Ecol 10:551-68. 2001
    ..Moreover, because adaptation is via substitutions of small effect, Fisher's model does not generate the strong effects of single chromosome regions often observed in species crosses...
  7. ncbi request reprint The stability of symmetric solutions to polygenic models
    N H Barton
    Institute of Cell, Animal and Population Biology, University of Edinburgh, West Mains Road, Edinburgh, EH9 3JT, Scotland
    Theor Popul Biol 57:249-63. 2000
    ..This allows the stability of symmetrical solutions to be determined. We apply the method to stabilizing and disruptive selection in a single deme and to selection against heterozygotes in a linear cline...
  8. ncbi request reprint Why sex and recombination?
    N H Barton
    Institute of Cell, Animal and Population Biology, University of Edinburgh, West Mains Road, Edinburgh EH9 3JT, UK
    Science 281:1986-90. 1998
    ..Various processes that can cause such an effect have been studied theoretically. It has, however, so far proved hard to discriminate among them empirically...
  9. doi request reprint On the application of statistical physics to evolutionary biology
    N H Barton
    Institute of Evolutionary Biology, School of Biological Sciences, University of Edinburgh, Kings Buildings, Edinburgh EH9 3JT, UK
    J Theor Biol 259:317-24. 2009
    ..This analogy with statistical thermodynamics brings together previous ideas in a general framework, and justifies a maximum entropy approximation to the dynamics of quantitative traits...
  10. ncbi request reprint The effect of epistasis on the structure of hybrid zones
    N H Barton
    Institute of Cell, Animal and Population Biology, University of Edinburgh, UK
    Genet Res 75:179-98. 2000
    ..For beta > 1, gene number is systematically overestimated and, conversely, when beta < 1, it is underestimated...
  11. pmc A comparison of multilocus clines maintained by environmental adaptation or by selection against hybrids
    L E Kruuk
    Institute of Cell, Animal and Population Biology, University of Edinburgh, Edinburgh EH9 3JT, United Kingdom
    Genetics 153:1959-71. 1999
    ..There is a smooth transition between a system in which a set of loci effectively act independently of each other and one in which they act as a single nonrecombining unit...
  12. doi request reprint The effect of a barrier to gene flow on patterns of geographic variation
    N H Barton
    Institute of Evolutionary Biology, University of Edinburgh, Kings Buildings, West Mains Road, Edinburgh, Scotland, UK
    Genet Res (Camb) 90:139-49. 2008
    ..Thus, in a two-dimensional population, barriers to gene flow can be detected through their effect on the spatial pattern of genetic marker alleles...
  13. pmc Testing for epistasis between deleterious mutations
    S A West
    Institute of Cell, Animal and Population Biology, University of Edinburgh, Edinburgh EH9 3JT, United Kingdom
    Genetics 149:435-44. 1998
    ..We also reconsider experimental data collected on Chlamydomonas moewussi using two of the three methods. Finally, we suggest how the test could be applied to diploid species...
  14. ncbi request reprint The limitations of adaptive dynamics as a model of evolution
    N H Barton
    School of Biological Science, University of Edinburgh, Edinburgh, UK
    J Evol Biol 18:1186-90. 2005
  15. ncbi request reprint Evolutionary biology: how did the human species form?
    N H Barton
    Institute of Evolutionary Biology, University of Edinburgh, Kings Buildings, Edinburgh, EH9 3JT, UK
    Curr Biol 16:R647-50. 2006
    ..Although this is consistent with "hybridisation" between the diverging human and chimp lineages, such observations can be explained more simply by the null model of allopatric speciation...
  16. pmc The effect of selection on genealogies
    N H Barton
    Institute of Cell, Animal and Population Biology, University of Edinburgh, Edinburgh EH9 3JT, UK
    Genetics 166:1115-31. 2004
    ..Moreover, small fluctuations in allele frequency due to random drift can greatly reduce any such effects. This will make it difficult to detect the action of selection from neutral variation alone...
  17. pmc Genetic hitchhiking
    N H Barton
    Institute of Cell, Animal and Population Biology, University of Edinburgh, UK
    Philos Trans R Soc Lond B Biol Sci 355:1553-62. 2000
    ..However, it seems unlikely that such sweeps can be sufficiently frequent to increase significantly the drift of neutral alleles...
  18. ncbi request reprint Measuring fitness by means of balancer chromosomes
    N H Barton
    Institute of Cell, Animal and Population Biology, University of Edinburgh, UK
    Genet Res 75:297-313. 2000
    ..A full age-structured model can also be applied to the data from both types of experiment. For the invasion method, this gives fitness estimates close to those from the discrete generation model...