Research Topics
Species | Emma BarrowSummaryCountry: UK Publications
| Collaborators |
Detail Information
Publications
Cost analysis of biomarker testing for mismatch repair deficiency in node-positive colorectal cancerE Barrow
Department of General Surgery, Manchester Royal Infirmary, St Mary s Hospital, Manchester, UK
Br J Surg 95:868-75. 2008..The evidence suggests that patients with tumours caused by defective DNA MMR do not benefit from 5-fluorouracil (5-FU)-based chemotherapy...
Colorectal cancer in HNPCC: cumulative lifetime incidence, survival and tumour distribution. A report of 121 families with proven mutationsE Barrow
Department of General Surgery, Manchester Royal Infirmary, Manchester, UK
Clin Genet 74:233-42. 2008..Current colonoscopic screening guidelines are appropriate...
Cumulative lifetime incidence of extracolonic cancers in Lynch syndrome: a report of 121 families with proven mutationsE Barrow
Department of General Surgery, Manchester Royal Infirmary, Manchester, UK
Clin Genet 75:141-9. 2009..0003). Gastric cancer risk in those born after 1935 does not justify surveillance. These penetrance estimates have been corrected for ascertainment bias and are appropriate for those referred to a high-risk clinic...
Semiquantitative assessment of immunohistochemistry for mismatch repair proteins in Lynch syndromeEmma Barrow
Department of General Surgery, Manchester Royal Infirmary, Manchester, M13 9WL, UK
Histopathology 56:331-44. 2010..To assess semiquantitative immunohistochemistry as used in the diagnosis of Lynch syndrome...
A comparative study of quantitative immunohistochemistry and quantum dot immunohistochemistry for mutation carrier identification in Lynch syndromeEmma Barrow
Department of General Surgery, Manchester Royal Infirmary, Oxford Road, Manchester, UK
J Clin Pathol 64:208-14. 2011..Quantum dots (QDs) are novel fluorescent labels that enable quantitative multiplex staining. This study compared their use with quantitative 3,3'-diaminobenzidine (DAB) IHC for the diagnosis of Lynch Syndrome...
