Gillian C Barnett

Summary

Country: UK

Publications

  1. ncbi request reprint A genome wide association study (GWAS) providing evidence of an association between common genetic variants and late radiotherapy toxicity
    Gillian C Barnett
    Centre for Cancer Genetic Epidemiology, University of Cambridge, Strangeways Research Laboratory, UK University of Cambridge, Department of Oncology, Oncology Centre, Cambridge University Hospitals NHS Foundation Trust, UK Electronic address
    Radiother Oncol 111:178-85. 2014
  2. pmc Genetics and genomics of radiotherapy toxicity: towards prediction
    Catharine M West
    School of Cancer and enabling Sciences, The University of Manchester, Manchester Academic Health Science Centre, The Christie, Wilmslow Road, Manchester M20 4BX, UK
    Genome Med 3:52. 2011
  3. pmc Individual patient data meta-analysis shows no association between the SNP rs1800469 in TGFB and late radiotherapy toxicity
    Gillian C Barnett
    Cambridge University Hospital NHS Foundation Trust, UK
    Radiother Oncol 105:289-95. 2012
  4. doi request reprint Standardized Total Average Toxicity score: a scale- and grade-independent measure of late radiotherapy toxicity to facilitate pooling of data from different studies
    Gillian C Barnett
    University of Cambridge Department of Oncology, Oncology Centre, Cambridge, UK
    Int J Radiat Oncol Biol Phys 82:1065-74. 2012
  5. doi request reprint Independent validation of genes and polymorphisms reported to be associated with radiation toxicity: a prospective analysis study
    Gillian C Barnett
    University of Cambridge, Department of Oncology, Cambridge, UK
    Lancet Oncol 13:65-77. 2012
  6. doi request reprint The impact of clinical factors on the development of late radiation toxicity: results from the Medical Research Council RT01 trial (ISRCTN47772397)
    G C Barnett
    University of Cambridge, Department of Oncology, Oncology Centre, Cambridge University Hospital NHS Foundation Trust, Cambridge, UK
    Clin Oncol (R Coll Radiol) 23:613-24. 2011
  7. pmc No association between SNPs regulating TGF-β1 secretion and late radiotherapy toxicity to the breast: results from the RAPPER study
    Gillian C Barnett
    Department of Oncology, University of Cambridge, Cambridge, UK
    Radiother Oncol 97:9-14. 2010
  8. pmc Normal tissue reactions to radiotherapy: towards tailoring treatment dose by genotype
    Gillian C Barnett
    Department of Oncology, University of Cambridge, Oncology Centre, Addenbrooke s Hospital, Hills Road, Cambridge CB2 0QQ, UK
    Nat Rev Cancer 9:134-42. 2009
  9. doi request reprint Risk factors for the incidence of breast cancer: do they affect survival from the disease?
    Gillian C Barnett
    Oncology Centre, Box 193, Addenbrooke s Hospital, Hills Rd, Cambridge, CB2 2QQ, United Kingdom
    J Clin Oncol 26:3310-6. 2008
  10. ncbi request reprint Information given to patients about adverse effects of radiotherapy: a survey of patients' views
    G C Barnett
    Oncology Centre, Addenbrooke s Hospital, Cambridge, UK
    Clin Oncol (R Coll Radiol) 16:479-84. 2004

Detail Information

Publications15

  1. ncbi request reprint A genome wide association study (GWAS) providing evidence of an association between common genetic variants and late radiotherapy toxicity
    Gillian C Barnett
    Centre for Cancer Genetic Epidemiology, University of Cambridge, Strangeways Research Laboratory, UK University of Cambridge, Department of Oncology, Oncology Centre, Cambridge University Hospitals NHS Foundation Trust, UK Electronic address
    Radiother Oncol 111:178-85. 2014
    ..This study was designed to identify common single nucleotide polymorphisms (SNPs) associated with toxicity 2years after radiotherapy...
  2. pmc Genetics and genomics of radiotherapy toxicity: towards prediction
    Catharine M West
    School of Cancer and enabling Sciences, The University of Manchester, Manchester Academic Health Science Centre, The Christie, Wilmslow Road, Manchester M20 4BX, UK
    Genome Med 3:52. 2011
    ..In this review, we highlight recent advances in radiotherapy and discuss results from four genome-wide studies of radiotoxicity...
  3. pmc Individual patient data meta-analysis shows no association between the SNP rs1800469 in TGFB and late radiotherapy toxicity
    Gillian C Barnett
    Cambridge University Hospital NHS Foundation Trust, UK
    Radiother Oncol 105:289-95. 2012
    ..To overcome publication bias, the international Radiogenomics Consortium collected and analysed individual patient level data from both published and unpublished studies...
  4. doi request reprint Standardized Total Average Toxicity score: a scale- and grade-independent measure of late radiotherapy toxicity to facilitate pooling of data from different studies
    Gillian C Barnett
    University of Cambridge Department of Oncology, Oncology Centre, Cambridge, UK
    Int J Radiat Oncol Biol Phys 82:1065-74. 2012
    ..We propose a novel metric, the Standardized Total Average Toxicity (STAT) score, to try to overcome these difficulties...
  5. doi request reprint Independent validation of genes and polymorphisms reported to be associated with radiation toxicity: a prospective analysis study
    Gillian C Barnett
    University of Cambridge, Department of Oncology, Cambridge, UK
    Lancet Oncol 13:65-77. 2012
    ..Few associations have been tested in independent validation studies. This prospective study aimed to validate reported associations between genotype and radiation toxicity in a large independent dataset...
  6. doi request reprint The impact of clinical factors on the development of late radiation toxicity: results from the Medical Research Council RT01 trial (ISRCTN47772397)
    G C Barnett
    University of Cambridge, Department of Oncology, Oncology Centre, Cambridge University Hospital NHS Foundation Trust, Cambridge, UK
    Clin Oncol (R Coll Radiol) 23:613-24. 2011
    ..The effect of other treatment- and patient-related factors is less well established. The aim of this study was to elucidate the influence of such factors in the development of late symptoms after radical radiotherapy to the prostate...
  7. pmc No association between SNPs regulating TGF-β1 secretion and late radiotherapy toxicity to the breast: results from the RAPPER study
    Gillian C Barnett
    Department of Oncology, University of Cambridge, Cambridge, UK
    Radiother Oncol 97:9-14. 2010
    ....
  8. pmc Normal tissue reactions to radiotherapy: towards tailoring treatment dose by genotype
    Gillian C Barnett
    Department of Oncology, University of Cambridge, Oncology Centre, Addenbrooke s Hospital, Hills Road, Cambridge CB2 0QQ, UK
    Nat Rev Cancer 9:134-42. 2009
    ..Variation in sensitivity to radiation is an inherited genetic trait and recent progress in genotyping raises the possibility of genome-wide studies to characterize genetic profiles that predict patient response to radiotherapy...
  9. doi request reprint Risk factors for the incidence of breast cancer: do they affect survival from the disease?
    Gillian C Barnett
    Oncology Centre, Box 193, Addenbrooke s Hospital, Hills Rd, Cambridge, CB2 2QQ, United Kingdom
    J Clin Oncol 26:3310-6. 2008
    ..Risk factors that influence the incidence of breast cancer may also affect survival after diagnosis...
  10. ncbi request reprint Information given to patients about adverse effects of radiotherapy: a survey of patients' views
    G C Barnett
    Oncology Centre, Addenbrooke s Hospital, Cambridge, UK
    Clin Oncol (R Coll Radiol) 16:479-84. 2004
    ..We present a study to evaluate the amount of information patients feel that they should be given...
  11. doi request reprint Randomized controlled trial of forward-planned intensity modulated radiotherapy for early breast cancer: interim results at 2 years
    Gillian C Barnett
    Department of Oncology, University of Cambridge, Cambridge University Hospitals, National Health Service Foundation Trust, Cambridge, United Kingdom
    Int J Radiat Oncol Biol Phys 82:715-23. 2012
    ..This single-center randomized trial was designed to investigate whether intensity-modulated radiotherapy (IMRT) reduces late toxicity in patients with early-stage breast cancer...
  12. doi request reprint Randomized controlled trial of intensity-modulated radiotherapy for early breast cancer: 5-year results confirm superior overall cosmesis
    Mukesh B Mukesh
    Mukesh B Mukesh, Gillian C Barnett, Jennifer S Wilkinson, Anne M Moody, Charles Wilson, Wendi Qian, Nicola Twyman, Neil G Burnet, and Charlotte E Coles, Cambridge University Hospitals National Health Service Foundation Trust Gillian C Barnett, Charleen Chan Wah Hak, and Neil G Burnet, University of Cambridge and Gordon C Wishart, Anglia Ruskin University, Cambridge, United Kingdom
    J Clin Oncol 31:4488-95. 2013
    ..The Cambridge Breast IMRT trial investigated this hypothesis, and the 5-year results are reported...
  13. ncbi request reprint Patient reported outcome measures (PROMs) following forward planned field-in field IMRT: Results from the Cambridge Breast IMRT trial
    Mukesh B Mukesh
    Oncology Centre, Cambridge University Hospitals NHS Foundation Trust, UK Department of Oncology, Colchester Hospital University NHS Foundation Trust, Essex, UK Electronic address
    Radiother Oncol 111:270-5. 2014
    ....
  14. doi request reprint A randomised controlled trial of forward-planned radiotherapy (IMRT) for early breast cancer: baseline characteristics and dosimetry results
    Gillian C Barnett
    Department of Oncology, University of Cambridge, Cambridge, UK
    Radiother Oncol 92:34-41. 2009
    ..This paper reports baseline characteristics of trial participants and dosimetry results...