Nicklas Bonander

Summary

Affiliation: Aston University
Country: UK

Publications

  1. ncbi Altering the ribosomal subunit ratio in yeast maximizes recombinant protein yield
    Nicklas Bonander
    School of Life and Health Sciences, Aston University, Aston Triangle, Birmingham B4 7ET, UK
    Microb Cell Fact 8:10. 2009
  2. ncbi Increasing cell biomass in Saccharomyces cerevisiae increases recombinant protein yield: the use of a respiratory strain as a microbial cell factory
    Cecilia Ferndahl
    Chemical and Biological Engineering Molecular Biotechnology, Chalmers University of Technology, 412 96 Goteborg, Sweden
    Microb Cell Fact 9:47. 2010
  3. ncbi Relieving the first bottleneck in the drug discovery pipeline: using array technologies to rationalize membrane protein production
    Nicklas Bonander
    School of Life and Health Sciences, Aston University, Aston Triangle, Birmingham B4 7ET, UK
    Expert Rev Proteomics 6:501-5. 2009
  4. ncbi Transcriptome analysis of a respiratory Saccharomyces cerevisiae strain suggests the expression of its phenotype is glucose insensitive and predominantly controlled by Hap4, Cat8 and Mig1
    Nicklas Bonander
    School of Life and Health Sciences, Aston University, Aston Triangle, Birmingham, B4 7ET, UK
    BMC Genomics 9:365. 2008
  5. ncbi Understanding the yeast host cell response to recombinant membrane protein production
    Zharain Bawa
    School of Life and Health Sciences, Aston University, Birmingham, U K
    Biochem Soc Trans 39:719-23. 2011
  6. ncbi Structural characterization of CD81-Claudin-1 hepatitis C virus receptor complexes
    Nicklas Bonander
    School of Life and Health Sciences, Aston University, Birmingham B4 7ET, UK
    Biochem Soc Trans 39:537-40. 2011
  7. ncbi Design of improved membrane protein production experiments: quantitation of the host response
    Nicklas Bonander
    Department of Cell and Molecular Biology/Microbiology, , Sweden
    Protein Sci 14:1729-40. 2005
  8. ncbi Solution structure and functional ligand screening of HI0719, a highly conserved protein from bacteria to humans in the YjgF/YER057c/UK114 family
    Lisa Parsons
    Center for Advanced Research in Biotechnology, University of Maryland Biotechnology Institute, 9600 Gudelsky Drive, Rockville, Maryland 20850, USA
    Biochemistry 42:80-9. 2003
  9. ncbi Structure of the YibK methyltransferase from Haemophilus influenzae (HI0766): a cofactor bound at a site formed by a knot
    Kap Lim
    Center for Advanced Research in Biotechnology, University of Maryland Biotechnology Institute, Rockville, MD 20850, USA
    Proteins 51:56-67. 2003
  10. ncbi A catalytic mechanism for D-Tyr-tRNATyr deacylase based on the crystal structure of Hemophilus influenzae HI0670
    Kap Lim
    Center for Advanced Research in Biotechnology, University of Maryland Biotechnology Institute, Rockville, Maryland 20850, USA
    J Biol Chem 278:13496-502. 2003

Collaborators

Detail Information

Publications10

  1. ncbi Altering the ribosomal subunit ratio in yeast maximizes recombinant protein yield
    Nicklas Bonander
    School of Life and Health Sciences, Aston University, Aston Triangle, Birmingham B4 7ET, UK
    Microb Cell Fact 8:10. 2009
    ..abstract:..
  2. ncbi Increasing cell biomass in Saccharomyces cerevisiae increases recombinant protein yield: the use of a respiratory strain as a microbial cell factory
    Cecilia Ferndahl
    Chemical and Biological Engineering Molecular Biotechnology, Chalmers University of Technology, 412 96 Goteborg, Sweden
    Microb Cell Fact 9:47. 2010
    ....
  3. ncbi Relieving the first bottleneck in the drug discovery pipeline: using array technologies to rationalize membrane protein production
    Nicklas Bonander
    School of Life and Health Sciences, Aston University, Aston Triangle, Birmingham B4 7ET, UK
    Expert Rev Proteomics 6:501-5. 2009
    ..These advances offer hope that the bottleneck of membrane protein production can be relieved rationally...
  4. ncbi Transcriptome analysis of a respiratory Saccharomyces cerevisiae strain suggests the expression of its phenotype is glucose insensitive and predominantly controlled by Hap4, Cat8 and Mig1
    Nicklas Bonander
    School of Life and Health Sciences, Aston University, Aston Triangle, Birmingham, B4 7ET, UK
    BMC Genomics 9:365. 2008
    ..In this study, we compared the transcriptome of the resultant strain, V5.TM6*P, with that of its wild-type parent, V5, at different glucose concentrations...
  5. ncbi Understanding the yeast host cell response to recombinant membrane protein production
    Zharain Bawa
    School of Life and Health Sciences, Aston University, Birmingham, U K
    Biochem Soc Trans 39:719-23. 2011
    ..By relieving the bottlenecks to recombinant membrane protein production in yeast, we aim to contribute to the drug discovery pipeline, while providing insight into translational processes...
  6. ncbi Structural characterization of CD81-Claudin-1 hepatitis C virus receptor complexes
    Nicklas Bonander
    School of Life and Health Sciences, Aston University, Birmingham B4 7ET, UK
    Biochem Soc Trans 39:537-40. 2011
    ..Structural characterization of these purified proteins will allow us to define the mechanism(s) underlying virus-cell interactions and aid the design of therapeutic agents targeting early steps in the viral life cycle...
  7. ncbi Design of improved membrane protein production experiments: quantitation of the host response
    Nicklas Bonander
    Department of Cell and Molecular Biology/Microbiology, , Sweden
    Protein Sci 14:1729-40. 2005
    ....
  8. ncbi Solution structure and functional ligand screening of HI0719, a highly conserved protein from bacteria to humans in the YjgF/YER057c/UK114 family
    Lisa Parsons
    Center for Advanced Research in Biotechnology, University of Maryland Biotechnology Institute, 9600 Gudelsky Drive, Rockville, Maryland 20850, USA
    Biochemistry 42:80-9. 2003
    ....
  9. ncbi Structure of the YibK methyltransferase from Haemophilus influenzae (HI0766): a cofactor bound at a site formed by a knot
    Kap Lim
    Center for Advanced Research in Biotechnology, University of Maryland Biotechnology Institute, Rockville, MD 20850, USA
    Proteins 51:56-67. 2003
    ..The substrate-binding domain is absent in HI0766 sequence family and may be provided by another Haemophilus influenzae partner protein, which is yet to be identified...
  10. ncbi A catalytic mechanism for D-Tyr-tRNATyr deacylase based on the crystal structure of Hemophilus influenzae HI0670
    Kap Lim
    Center for Advanced Research in Biotechnology, University of Maryland Biotechnology Institute, Rockville, Maryland 20850, USA
    J Biol Chem 278:13496-502. 2003
    ..Based on this model, we propose a substrate-assisted acylation/deacylation-catalytic mechanism in which the amino group of the D-Tyr is deprotonated and serves as the general base...