Research Topics
Species | S H ArshadSummaryCountry: UK Publications
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Publications
Characterization of wheezing phenotypes in the first 10 years of lifeR J Kurukulaaratchy
The David Hide Asthma and Allergy Research Centre, St Mary s Hospital, Newport, Isle of Wight, UK
Clin Exp Allergy 33:573-8. 2003..Childhood wheezing illnesses are characterized into different phenotypes. However, severity of the disease associated with these phenotypes has not been extensively studied...
Characterisation of atopic and non-atopic wheeze in 10 year old childrenR J Kurukulaaratchy
The David Hide Asthma and Allergy Research Centre, St Mary's Hospital, Newport, Isle of Wight PO30 5TG, UK
Thorax 59:563-8. 2004..Different risk factor profiles appear relevant to the presence of atopic and non-atopic wheeze at 10 years of age...
Sensitization to common allergens and its association with allergic disorders at age 4 years: a whole population birth cohort studyS H Arshad
David Hide Asthma and Allergy Research Centre, St Mary s Hospital, Newport, Isle of Wight, United Kingdom
Pediatrics 108:E33. 2001..Although it is generally agreed that atopy is an important risk factor for allergic diseases such as asthma, rhinitis, and eczema, the extent to which atopy accounts for these diseases is controversial...
Prevalence and cumulative incidence of food hypersensitivity in the first 3 years of lifeC Venter
The David Hide Asthma and Allergy Research Centre, St Mary s Hospital, Newport, Isle of Wight, UK
Allergy 63:354-9. 2008..Prevalence and incidence of food hypersensitivity (FHS) and its trends in early childhood are unclear...
Association of allergy-related symptoms with sensitisation to common allergens in an adult European populationS H Arshad
The David Hide Asthma and Allergy Research Centre, St Mary s Hospital, Newport, Isle of Wight, UK
J Investig Allergol Clin Immunol 11:94-102. 2001..However, the relationship between atopy and allergic symptoms is not fully understood, and may not be the same for different allergy related symptoms and in differing environmental conditions...
The influence of gender and atopy on the natural history of rhinitis in the first 18 years of lifeR J Kurukulaaratchy
The David Hide Asthma and Allergy Research Centre, St Mary s Hospital, Newport, Isle of Wight, UK
Clin Exp Allergy 41:851-9. 2011..Longitudinal studies of the natural history of childhood and adolescent rhinitis are lacking...
Defining childhood atopic phenotypes to investigate the association of atopic sensitization with allergic diseaseR J Kurukulaaratchy
The David Hide Asthma and Allergy Research Centre, St Mary's Hospital, Newport, Isle of Wight, UK
Allergy 60:1280-6. 2005..The currently accepted childhood 'Allergic March' may oversimplify the natural history of childhood atopy and allergic disease...
Rhinitis in 10-year-old children and early life risk factors for its developmentS H Arshad
The David Hide Asthma and Allergy Research Centre, St Mary s Hospital, Newport, Isle of Wight, UK
Acta Paediatr 91:1334-8. 2002..To study the prevalence, characteristics of and risk factors for childhood rhinitis...
Predicting persistent disease among children who wheeze during early lifeR J Kurukulaaratchy
The David Hide Asthma and Allergy Research Centre, St Mary's Hospital, Newport, Isle of Wight, UK
Eur Respir J 22:767-71. 2003..Risk scores using such knowledge could provide prognostic guidance on the outcome of early wheeze...
Trends in cutaneous sensitization in the first 18 years of life: results from the 1989 Isle of Wight birth cohort studyG Roberts
The David Hide Asthma and Allergy Research Centre, St Mary s Hospital, Newport, UK
Clin Exp Allergy 42:1501-9. 2012..There are only limited data on the natural history of SPT results over childhood and adolescence...
Prevalence of sensitization reported and objectively assessed food hypersensitivity amongst six-year-old children: a population-based studyCarina Venter
The David Hide Asthma and Allergy Research Centre, St Mary's Hospital, Newport, Isle of Wight, UK
Pediatr Allergy Immunol 17:356-63. 2006..Milk, peanut and wheat were the key food allergens amongst those with positive challenges...
The diagnosis of Brazil nut allergy using history, skin prick tests, serum-specific immunoglobulin E and food challengesS Ridout
The David Hide Asthma and Allergy Research Centre, St Mary's Hospital, Newport, Isle of Wight, UK
Clin Exp Allergy 36:226-32. 2006..However, a doubtful history with SPT between 1 and 5 mm, or a serum-specific IgE less than 3.5 kU/L may require an oral challenge to help determine the risk of a Brazil nut allergic reaction...
Polymorphisms in the interleukin 13 and GATA binding protein 3 genes and the development of eczema during childhoodS H Arshad
The David Hide Asthma and Allergy Research Centre, St Mary s Hospital, Newport, Isle of Wight and IIR Research Division, University of Southampton, Southampton, UK
Br J Dermatol 158:1315-22. 2008..Atopic eczema is characterized by Th2-dominant immunity with the cytokine interleukin 13 and the transcription factor GATA binding protein 3 playing a critical role...
Primary prevention of asthma and atopy during childhood by allergen avoidance in infancy: a randomised controlled studyS H Arshad
The David Hide Asthma and Allergy Research Centre, St Mary s Hospital, Isle of Wight, UK
Thorax 58:489-93. 2003..Recent increases in the prevalence of asthma and atopy emphasise the need for devising effective methods for primary prevention in children at high risk of atopy...
Food allergen avoidance in primary prevention of food allergyS H Arshad
The David Hide Asthma and Allergy Research Centre, St Mary s Hospital, Isle of Wight, UK
Allergy 56:113-6. 2001....
The prevalence of asthma and wheezing illnesses amongst 10-year-old schoolchildrenR J Kurukulaaratchy
The David Hide Asthma and Allergy Research Centre, St Mary's Hospital, Newport, Isle of Wight, UK
Respir Med 96:163-9. 2002..In regard to prevalence and morbidity characteristics, a questionnaire-based definition of currently diagnosed asthma gave similar results to the use of symptomatic BHR in defining current asthma...
Efficacy and acceptability of a new topical skin lotion of sodium cromoglicate (Altoderm) in atopic dermatitis in children aged 2-12 years: a double-blind, randomized, placebo-controlled trialR Stainer
Synexus Limited, Crosby Clinical Research Centre, Burlington House, 3rd Floor, South Wing, Crosby Road North, Waterloo, Liverpool, UK
Br J Dermatol 152:334-41. 2005..None was reported as severe or very severe. CONCLUSIONS: These results show a clinically useful benefit of this sodium cromoglicate lotion in children with moderately severe AD...
Raised cord serum immunoglobulin E increases the risk of allergic sensitisation at ages 4 and 10 and asthma at age 10A Sadeghnejad
Department of Epidemiology, Michigan State University, East Lansing, Michigan, USA
Thorax 59:936-42. 2004..This is the second study suggesting that CS-IgE is also a risk factor for asthma at age 10, probably related to the late onset of asthma. This association is not necessarily mediated by allergic sensitisation...
Interleukin-1R antagonist gene and pre-natal smoke exposure are associated with childhood asthmaR A Ramadas
Comparative Medicine and Integrative Biology Graduate Programme, Michigan State University, East Lansing, MI, USA
Eur Respir J 29:502-8. 2007....
Does maternal immunoglobulin E decrease with increasing order of live offspring? Investigation into maternal immune toleranceW Karmaus
Department of Epidemiology, Michigan State University, East Lansing, MI 48823, USA
Clin Exp Allergy 34:853-9. 2004..Knowledge about causes behind the sibling effect may allow us to prevent atopic manifestations...
Prevention of sensitization to house dust mite by allergen avoidance in school age children: a randomized controlled studyS H Arshad
University Children s Hospital, Kaunas Medical University, Kaunas, Lithuania
Clin Exp Allergy 32:843-9. 2002..Sensitization to dust mites predisposes to asthma and allergic rhinitis, and prevention of this sensitization might reduce the rising prevalence of these disorders...
Predicting risk of asthma in wheezing infantsA Raza
Thorax 63:842; author reply 842. 2008
Effect of mite-impermeable mattress encasings and an educational package on the development of allergies in a multinational randomized, controlled birth-cohort study -- 24 months results of the Study of Prevention of Allergy in Children in EuropeF Horak
University Children's Hospital, Vienna, Austria
Clin Exp Allergy 34:1220-5. 2004..25.8%) could be found between the control and intervention group. CONCLUSION: In this study, HDM avoidance did not show a protective effect on the development of sensitization to HDM or symptomatic allergy in children at age 24 months...
