I Ahmad

Summary

Country: UK

Publications

  1. doi Advances in mouse models of prostate cancer
    Imran Ahmad
    The Beatson Institute for Cancer Research, Glasgow, UK
    Expert Rev Mol Med 10:e16. 2008
  2. doi Keratinizing squamous metaplasia of the bladder: a review
    Imran Ahmad
    Beatson Institute for Cancer Research, Glasgow, UK
    Urol Int 81:247-51. 2008
  3. ncbi Change in functional status of patients whilst awaiting prinmary total knee arthroplasty
    I Ahmad
    Western Infirmary, Dumbarton Road, Glasgow
    Surgeon 5:266-7. 2007
  4. ncbi Sequential hydrodistension and intravesical instillation of hyaluronic acid under general anaesthesia for treatment of refractory interstitial cystitis: a pilot study
    Imran Ahmad
    Department of Urology, Southern General Hospital, Glasgow, UK
    Int Urogynecol J Pelvic Floor Dysfunct 19:543-6. 2008
  5. ncbi Urological follow-up of adult spina bifida patients
    Imran Ahmad
    Department of Urology, Southern General Hospital, Glasgow, Scotland, United Kingdom
    Neurourol Urodyn 26:978-80. 2007
  6. ncbi Isolated deep peroneal (fibular) nerve palsy in association with primary total hip arthroplasty
    I Ahmad
    Department of Urology, Southern General Hospital, Glasgow, Scotland, UK
    Clin Anat 20:703-4. 2007
  7. ncbi Hemospermia
    Imran Ahmad
    Department of Urology, Ayr Hospital, Ayr, Scotland, United Kingdom
    J Urol 177:1613-8. 2007
  8. ncbi Testicular microlithiasis: prevalence and risk of concurrent and interval development of testicular tumor in a referred population
    Imran Ahmad
    Department of Urology, Ayr Hospital, Dalmellington Road, Ayr, KA6 6DX, UK
    Int Urol Nephrol 39:1177-81. 2007
  9. ncbi Ezetimibe-induced acute pancreatitis
    Imran Ahmad
    Mercy Fitzgerald Hospital, Darby, PA, USA
    South Med J 100:409-10. 2007
  10. ncbi Complicated inguinal hernia of Amyand
    Mateen M Hotiana
    South Med J 100:411. 2007

Collaborators

  • Owen Sansom
  • Hing Y Leung
  • Ying Zhang
  • Ajai Pal
  • Chuanbo Zhang
  • Usha N Kasid
  • Prafulla C Gokhale
  • Sumsullah Khan
  • Ateeq Ahmad
  • Isamu Sakabe
  • Deepak Kumar
  • Saifuddin Sheikh
  • Rajshree R Mewani
  • Anatoly Dritschilo
  • Aquilur Rahman
  • Mateen M Hotiana
  • Jenifer L Johnson
  • Shoukath M Ali
  • Shahid Ali
  • Allen Zhang
  • Usha Kasid
  • Constantinos G Broustas
  • Sabrina Lei
  • Christopher Semsarian
  • Sarba Kundu
  • Debyani Chakravarty
  • Howard E Boudreau
  • Yue Fen Wang
  • Sofia Bardin
  • Wei Guo
  • Moghis U Ahmad
  • Paul Chen
  • Narayan Kamath
  • Danielle Carbonaro
  • June Zang
  • Jeffrey X Duggan
  • Abdul R Khan
  • Asis K Sarkar
  • Pei Yu Chien
  • Theresa L Whiteside
  • Sonal Patel
  • Edmund A Gehan
  • Wenhua Tang
  • Jin Pei
  • Joseph T Newsome
  • Joachim P Schmitt
  • Dimitrios Georgakopoulos
  • Michael Giewat
  • J G Seidman
  • Steven Reiken
  • Ulrike Mende
  • Andrew R Marks
  • David A Kass
  • Christine E Seidman
  • Bradley K McConnell

Detail Information

Publications22

  1. doi Advances in mouse models of prostate cancer
    Imran Ahmad
    The Beatson Institute for Cancer Research, Glasgow, UK
    Expert Rev Mol Med 10:e16. 2008
    ..Compound mutational models will also develop further, with double and triple knock-in or knockout systems adding to our knowledge of the interaction between different signalling cascades...
  2. doi Keratinizing squamous metaplasia of the bladder: a review
    Imran Ahmad
    Beatson Institute for Cancer Research, Glasgow, UK
    Urol Int 81:247-51. 2008
    ..Once diagnosed, there is a dilemma how to treat and follow-up this group...
  3. ncbi Change in functional status of patients whilst awaiting prinmary total knee arthroplasty
    I Ahmad
    Western Infirmary, Dumbarton Road, Glasgow
    Surgeon 5:266-7. 2007
    ..To investigate the effect of waiting lists on the rate of change in the functional status of patients awaiting total knee joint replacement...
  4. ncbi Sequential hydrodistension and intravesical instillation of hyaluronic acid under general anaesthesia for treatment of refractory interstitial cystitis: a pilot study
    Imran Ahmad
    Department of Urology, Southern General Hospital, Glasgow, UK
    Int Urogynecol J Pelvic Floor Dysfunct 19:543-6. 2008
    ..Further prospective trials are required...
  5. ncbi Urological follow-up of adult spina bifida patients
    Imran Ahmad
    Department of Urology, Southern General Hospital, Glasgow, Scotland, United Kingdom
    Neurourol Urodyn 26:978-80. 2007
    ..Our aim was to evaluate the current literature to attempt to formulate evidence based guidelines for the management of this difficult group of patients...
  6. ncbi Isolated deep peroneal (fibular) nerve palsy in association with primary total hip arthroplasty
    I Ahmad
    Department of Urology, Southern General Hospital, Glasgow, Scotland, UK
    Clin Anat 20:703-4. 2007
    ..Recovery is prolonged and incomplete despite intensive physiotherapy, thus putting emphasis on prevention...
  7. ncbi Hemospermia
    Imran Ahmad
    Department of Urology, Ayr Hospital, Ayr, Scotland, United Kingdom
    J Urol 177:1613-8. 2007
    ..The dilemma now is how far to investigate these patients since in the majority it is a benign and self-limiting symptom...
  8. ncbi Testicular microlithiasis: prevalence and risk of concurrent and interval development of testicular tumor in a referred population
    Imran Ahmad
    Department of Urology, Ayr Hospital, Dalmellington Road, Ayr, KA6 6DX, UK
    Int Urol Nephrol 39:1177-81. 2007
    ..To identify prevalence of testicular microlithiasis on ultrasound in a referred population and risk of concurrent and interval testicular tumor development...
  9. ncbi Ezetimibe-induced acute pancreatitis
    Imran Ahmad
    Mercy Fitzgerald Hospital, Darby, PA, USA
    South Med J 100:409-10. 2007
    ..It is used alone or in combination with other lipid-lowering agents in the treatment of various forms of hypercholesterolemia. Since its FDA approval in 2002, there are no known citations of ezetimibe-induced pancreatitis...
  10. ncbi Complicated inguinal hernia of Amyand
    Mateen M Hotiana
    South Med J 100:411. 2007
  11. ncbi Typhoid fever and viral hepatitis in a G6PD deficient individual
    Imran Ahmad
    CMH Sibi, Pakistan
    J Ayub Med Coll Abbottabad 17:80-1. 2005
    ..Simultaneous occurrence of multiple diseases is unusual but not rare. We are reporting an unusual combination of Typhoid fever and viral hepatitis in a G6PD deficient individual...
  12. ncbi Role of SCC-S2 in experimental metastasis and modulation of VEGFR-2, MMP-1, and MMP-9 expression
    Chuanbo Zhang
    Department of Radiation Medicine, Lombardi Cancer Center, Georgetown University Medical Center, Washington, DC 20007, USA
    Mol Ther 13:947-55. 2006
    ..These results demonstrate a novel role for SCC-S2 in tumor progression, involving multiple effectors, and provide a basis for SCC-S2-targeted cancer gene therapy...
  13. ncbi Pharmacokinetics, toxicity, and efficacy of ends-modified raf antisense oligodeoxyribonucleotide encapsulated in a novel cationic liposome
    Prafulla C Gokhale
    Department of Radiation Medicine, Lombardi Cancer Center, Georgetown University Medical Center, Washington, DC 20057, USA
    Clin Cancer Res 8:3611-21. 2002
    ..LErafAON treatment caused inhibition of Raf-1 protein expression in normal and tumor tissues in these mice (>50%, versus controls). These data have formed a basis of the clinical Phase I studies of LErafAON for cancer treatment...
  14. ncbi SCC-112, a novel cell cycle-regulated molecule, exhibits reduced expression in human renal carcinomas
    Deepak Kumar
    Department of Radiation Medicine, Lombardi Cancer Center, Georgetown University, E208, Research Building, 3970 Reservoir Road, NW, Washington, DC 20007, USA
    Gene 328:187-96. 2004
    ..2-fold to>10-fold, n=18). Taken together, these findings suggest that the SCC-112 gene expression is likely to be associated with normal cell growth and proliferation...
  15. ncbi Enhanced therapeutic effects of doxorubicin and paclitaxel in combination with liposome-entrapped ends-modified raf antisense oligonucleotide against human prostate, lung and breast tumor models
    Rajshree R Mewani
    Department of Radiation Medicine, Georgetown University Medical Center, NW, Washington, DC 20057, USA
    Int J Oncol 24:1181-8. 2004
    ..These preclinical observations support the use of LErafAON in combination with chemotherapeutic agents to improve the treatment of human cancers...
  16. ncbi BRCC2, a novel BH3-like domain-containing protein, induces apoptosis in a caspase-dependent manner
    Constantinos G Broustas
    Department of Radiation Medicine, Lombardi Cancer Center, Georgetown University, Washington, D C 20057, USA
    J Biol Chem 279:26780-8. 2004
    ..These findings demonstrate that BRCC2 functions as a proapoptotic molecule and suggest that BRCC2 induces a caspase-dependent mitochondrial pathway of cell death...
  17. ncbi Enhanced therapeutic efficacy of a novel liposome-based formulation of SN-38 against human tumor models in SCID mice
    Sabrina Lei
    Research and Development, NeoPharm Inc, Waukegan, IL 60085, USA
    Anticancer Drugs 15:773-8. 2004
    ..We conclude that LE-SN38 is a novel liposome-based formulation with enhanced therapeutic efficacy against human tumor models...
  18. ncbi Quantification of raf antisense oligonucleotide (rafAON) in biological matrices by LC-MS/MS to support pharmacokinetics of a liposome-entrapped rafAON formulation
    Jenifer L Johnson
    Pharmacokinetics, Safety and Efficacy Department, NeoPharm Inc, Waukegan, IL 60085, USA
    Biomed Chromatogr 19:272-8. 2005
    ..Accuracy, precision and stability were evaluated and found to be acceptable in all three matrices. The assay was used to support pharmacokinetics and tissue distribution studies of LErafAON-ETU in mice and monkeys...
  19. ncbi Systemic delivery of RafsiRNA using cationic cardiolipin liposomes silences Raf-1 expression and inhibits tumor growth in xenograft model of human prostate cancer
    Ajai Pal
    Pharmacokinetics, Safety and Efficacy Department, NeoPharm Inc, Research and Development, 1850 Lakeside Drive, Waukegan, IL 60085, USA
    Int J Oncol 26:1087-91. 2005
    ..The knockdown of Raf-1 expression by siRNA is also associated with down-regulation of cyclin D1 expression in vivo...
  20. ncbi Preclinical safety, pharmacokinetics and antitumor efficacy profile of liposome-entrapped SN-38 formulation
    Ajai Pal
    NeoPharm, Inc, Research and Development, Waukegan, IL 60085, USA
    Anticancer Res 25:331-41. 2005
    ..Its poor solubility restricted its development as an anticancer agent. We have developed an easy-to-use liposome-entrapped SN-38 (LE-SN38) and evaluated its toxicology, pharmacokinetics and antitumor efficacy profile...
  21. ncbi Synthesis and biological evaluation of gemcitabine-lipid conjugate (NEO6002)
    Shoukath M Ali
    NeoPharm Inc, Research and Development Facility, 1850 Lakeside Drive, Waukegan, IL 60085, USA
    Bioorg Med Chem Lett 15:2571-4. 2005
    ..Compound 5 was tested in BxPC-3 human pancreatic tumor model in SCID mice and exhibited promising activity and lower toxicity when compared with Gemzar...
  22. pmc The L-type calcium channel inhibitor diltiazem prevents cardiomyopathy in a mouse model
    Christopher Semsarian
    Department of Genetics, Howard Hughes Medical Institute and Harvard Medical School, 200 Longwood Avenue, Boston, MA 02115, USA
    J Clin Invest 109:1013-20. 2002
    ....