Adetola B Adesida

Summary

Country: UK

Publications

  1. ncbi The effects of ageing on proliferation potential, differentiation potential and cell surface characterisation of human mesenchymal stem cells
    Emma Fossett
    University College London Institute for Orthopaedics and Musculoskeletal Sciences, Royal National Orthopaedic Hospital, Stanmore HA7 4LP, United Kingdom
    Curr Stem Cell Res Ther 7:282-6. 2012
  2. pmc Bilateral suprascapular nerve entrapment by ganglion cyst associated with superior labral lesion
    Giacomo Rizzello
    Department of Orthopaedic and Trauma Surgery Campus Bio Medico University, Via Alvaro del Portillo, 200, 00128 Trigoria, Rome, Italy Centro Integrato di Ricerca CIR Campus Bio Medico University, Via Alvaro del Portillo, 21, 00128, Rome, Italy
    Open Orthop J 7:129-32. 2013
  3. pmc Mesenchymal stem cells and articular cartilage repair: clinical studies and future direction
    Shahid Punwar
    Department of Trauma and Orthopaedics, Frenchay Hospital, North Bristol NHS Trust, Bristol, BS16 1LE, UK
    Open Orthop J 5:296-301. 2011
  4. pmc Ligament tissue engineering and its potential role in anterior cruciate ligament reconstruction
    E W Yates
    Department of Trauma and Orthopaedics, Stepping Hill Hospital, Stockport NHS Foundation Trust, Stockport, SK2 7JE, UK
    Stem Cells Int 2012:438125. 2012
  5. pmc Optimising human mesenchymal stem cell numbers for clinical application: a literature review
    E Fossett
    University College London Institute for Orthopaedics and Musculoskeletal Sciences, Royal National Orthopaedic Hospital, Stanmore HA7 4LP, UK
    Stem Cells Int 2012:465259. 2012
  6. ncbi Mesenchymal stem cells, sources of cells and differentiation potential
    Wasim S Khan
    University College London Institute of Orthopaedics and Musculoskeletal Sciences, Royal National Orthopaedic Hospital, Stanmore, London HA7 4LP, UK
    J Stem Cells 7:75-85. 2012
  7. ncbi The characterisation of mesenchymal stem cells: a stem cell is not a stem cell is not a stem cell
    Wasim S Khan
    University College London Institute of Orthopaedics and Musculoskeletal Sciences, Royal National Orthopaedic Hospital, Stanmore, London HA7 4LP, UK
    J Stem Cells 7:87-95. 2012
  8. ncbi Cartilage tissue engineering approaches applicable in orthopaedic surgery: the past, the present, and the future
    Wasim S Khan
    University College London Institute of Orthopaedics and Musculoskeletal Sciences, Royal National Orthopaedic Hospital, Stanmore, London HA7 4LP, UK
    J Stem Cells 7:97-104. 2012
  9. doi Foreword: stem cell applications and tissue engineering approaches in sports medicine- from bench to bedside
    Wasim Khan
    Royal National Orthopaedic Hospital, Stanmore, Middlesex, UK
    J Stem Cells 5:149-54. 2010
  10. ncbi Regulation of differentiation of mesenchymal stem cells into musculoskeletal cells
    Gopiga Thanabalasundaram
    University College London Institute of Orthopaedics and Musculoskeletal Sciences, Royal National Orthopaedic Hospital, Stanmore, Middlesex, HA7 4LP, United Kingdom
    Curr Stem Cell Res Ther 7:95-102. 2012

Collaborators

  • M Agarwal
  • Simon R Tew
  • Umile Giuseppe Longo
  • Giacomo Rizzello
  • Nicola Maffulli
  • S Jane Millward-Sadler
  • Hiteshkumar D Tailor
  • Wasim S Khan
  • W S Khan
  • Timothy E Hardingham
  • W Khan
  • Wasim Khan
  • A A Malik
  • Emma Fossett
  • S Maclean
  • E Fossett
  • E W Yates
  • Gopiga Thanabalasundaram
  • Shahid Punwar
  • B Spiegelberg
  • Claire Hall
  • D S Johnson
  • L Nokes
  • R K Jones
  • N Fahmy
  • Nikita Arumalla
  • Philip Pastides
  • M Snow
  • S Anand
  • G T Foley
  • S J Anand
  • S Cartmell
  • A Rupani
  • Nabil R M Fahmy
  • Peter Smitham
  • T Parratt
  • D R Marsh
  • Emeka Oragui
  • Emma T Lowe
  • Edwin Akagha
  • R Jennings
  • David S Johnson
  • S K Dheerendra
  • Sohail I Ahmed
  • David H Sochart
  • Atif A Malik
  • Mamun Al-Rashid
  • Matthew Ravenscroft
  • Bernice Dillon
  • T E Hardingham
  • David R Marsh
  • J G Andrew
  • Max Fehily
  • E M Holt
  • J Denton
  • A G Cox
  • R Dalal
  • L Funk
  • L Muir

Detail Information

Publications37

  1. ncbi The effects of ageing on proliferation potential, differentiation potential and cell surface characterisation of human mesenchymal stem cells
    Emma Fossett
    University College London Institute for Orthopaedics and Musculoskeletal Sciences, Royal National Orthopaedic Hospital, Stanmore HA7 4LP, United Kingdom
    Curr Stem Cell Res Ther 7:282-6. 2012
    ..This paper will look at how ageing effects proliferation potential, differentiation potential and cell surface characterisation of human mesenchymal stem cells...
  2. pmc Bilateral suprascapular nerve entrapment by ganglion cyst associated with superior labral lesion
    Giacomo Rizzello
    Department of Orthopaedic and Trauma Surgery Campus Bio Medico University, Via Alvaro del Portillo, 200, 00128 Trigoria, Rome, Italy Centro Integrato di Ricerca CIR Campus Bio Medico University, Via Alvaro del Portillo, 21, 00128, Rome, Italy
    Open Orthop J 7:129-32. 2013
    ..We performed simultaneous suture anchor SLAP repair and cyst decompression with a blunt probe. Upon a two-year follow-up, patients recovered full shoulder function without pain or limitations in activities of daily living...
  3. pmc Mesenchymal stem cells and articular cartilage repair: clinical studies and future direction
    Shahid Punwar
    Department of Trauma and Orthopaedics, Frenchay Hospital, North Bristol NHS Trust, Bristol, BS16 1LE, UK
    Open Orthop J 5:296-301. 2011
    ....
  4. pmc Ligament tissue engineering and its potential role in anterior cruciate ligament reconstruction
    E W Yates
    Department of Trauma and Orthopaedics, Stepping Hill Hospital, Stockport NHS Foundation Trust, Stockport, SK2 7JE, UK
    Stem Cells Int 2012:438125. 2012
    ..We evaluate the current literature on ligament tissue engineering and its role in anterior cruciate ligament reconstruction...
  5. pmc Optimising human mesenchymal stem cell numbers for clinical application: a literature review
    E Fossett
    University College London Institute for Orthopaedics and Musculoskeletal Sciences, Royal National Orthopaedic Hospital, Stanmore HA7 4LP, UK
    Stem Cells Int 2012:465259. 2012
    ..Further research is required to reduce the risk of infection, loss of cell characterisation in cell culture, and making cell-based therapies more cost effective through creating rapid expansion of MSCs regardless of patient factors...
  6. ncbi Mesenchymal stem cells, sources of cells and differentiation potential
    Wasim S Khan
    University College London Institute of Orthopaedics and Musculoskeletal Sciences, Royal National Orthopaedic Hospital, Stanmore, London HA7 4LP, UK
    J Stem Cells 7:75-85. 2012
    ..g. osteoblast or chondrocyte, using predefined culture conditions before being used for clinical applications. In this paper stem cells are discussed including their various sources and their differentiation potential...
  7. ncbi The characterisation of mesenchymal stem cells: a stem cell is not a stem cell is not a stem cell
    Wasim S Khan
    University College London Institute of Orthopaedics and Musculoskeletal Sciences, Royal National Orthopaedic Hospital, Stanmore, London HA7 4LP, UK
    J Stem Cells 7:87-95. 2012
    ..In this paper the characterisation of stem cells is discussed followed by preliminary evidence suggesting that pericytes may be a candidate stem cell...
  8. ncbi Cartilage tissue engineering approaches applicable in orthopaedic surgery: the past, the present, and the future
    Wasim S Khan
    University College London Institute of Orthopaedics and Musculoskeletal Sciences, Royal National Orthopaedic Hospital, Stanmore, London HA7 4LP, UK
    J Stem Cells 7:97-104. 2012
    ..In this paper we discuss the structure, function and embryology of cartilage and osteoarthritis. This is followed by a review of current treatment strategies for the repair of cartilage and the use of tissue engineering...
  9. doi Foreword: stem cell applications and tissue engineering approaches in sports medicine- from bench to bedside
    Wasim Khan
    Royal National Orthopaedic Hospital, Stanmore, Middlesex, UK
    J Stem Cells 5:149-54. 2010
    ..This is due to many factors including the familiarity with bone marrow derived mesenchymal stem cells...
  10. ncbi Regulation of differentiation of mesenchymal stem cells into musculoskeletal cells
    Gopiga Thanabalasundaram
    University College London Institute of Orthopaedics and Musculoskeletal Sciences, Royal National Orthopaedic Hospital, Stanmore, Middlesex, HA7 4LP, United Kingdom
    Curr Stem Cell Res Ther 7:95-102. 2012
    ..Strict regulation of differentiation of MSCs is essential for a positive outcome of the particular tissue treated with MSCs, especially due to the fact that capacity to differentiate decreases with increasing age of the donor...
  11. pmc A rare case of arterial avulsion presenting with occult blood loss following total hip arthroplasty: a case report
    Claire Hall
    Department of Trauma and Orthopaedics, North Manchester General Hospital, Crumpsall Street, Manchester, M8 5RB, UK
    J Med Case Reports 3:9320. 2009
    ..To the best of our knowledge, this is the first reported case of an avulsion injury to a posterior branch of the profunda femoral artery during primary hip arthroplasty...
  12. ncbi Stem cell applications and tissue engineering approaches in surgical practice
    Wasim S Khan
    United Kingdom Centre for Tissue Engineering, University of Manchester
    J Perioper Pract 19:130-5. 2009
    ..Significant hurdles however remain to be overcome before tissue engineering becomes more routinely used in surgical practice...
  13. ncbi Management of intra-articular fractures of the proximal interphalangeal joint by internal fixation and bone grafting
    W Khan
    Department of Orthopaedics and Trauma, Hope Hospital, Stott Lane, Salford, M6 8HD, United Kingdom
    Arch Orthop Trauma Surg 124:688-91. 2004
    ..We describe a procedure where bone grafting and internal fixation are used to restore the articular surface...
  14. ncbi The S-Quattro in the management of acute intraarticular phalangeal fractures of the hand
    W Khan
    Department of Orthopaedics and Trauma, Stepping Hill Hospital, Stockport, UK
    J Hand Surg Br 31:79-92. 2006
    ..This device is a simple and effective technique for the management of these difficult fractures. It offers advantages in terms of versatility, ease of application, good tolerance by patients, few complications and good outcome...
  15. ncbi The S-Quattro in the management of sports injuries of the fingers
    W Khan
    Orthopaedic Department, Stepping Hill Hospital, Stockport SK7 2JE, United Kingdom
    Injury 37:860-8. 2006
    ..It is relatively free of complications with good results. We advocate the routine use of the S-Quattro in view of its inherent simplicity and the good results it produces with these difficult sports injuries...
  16. ncbi The relationship of the angle of immobilisation of the knee to the force applied to the extensor mechanism when partially weight-bearing. A gait-analysis study in normal volunteers
    W S Khan
    Department of Trauma and Orthopaedics, Stockport NHS Foundation Trust, Stockport SK2 7JE, UK
    J Bone Joint Surg Br 89:911-4. 2007
    ..We recommend that for potentially unstable injuries of the extensor mechanism, when mobilising with partial weight-bearing, the knee should be flexed at no more than 10 degrees...
  17. ncbi How accurate are lockable orthotic knee braces? An objective gait analysis study
    W S Khan
    Department of Trauma and Orthopaedics, Stockport NHS Foundation Trust, Stepping Hill Hospital, Stockport, UK
    Knee 14:497-9. 2007
    ..This study highlights inaccuracies in a knee brace at low knee flexion angles. The higher actual angles alter the biomechanics of the knee joint and result in greater forces across the knee joint and especially the extensor mechanism...
  18. doi Chromium, cobalt and titanium metallosis involving a Nottingham shoulder replacement
    W S Khan
    Musculoskeletal Research Group, University of Manchester, Oxford Road, Manchester M13 9PT, UK
    J Bone Joint Surg Br 90:502-5. 2008
    ..There was metallosis despite exchange of the modular humeral head. Both components had to be exchanged to resolve the problem...
  19. pmc Human infrapatellar fat pad-derived stem cells express the pericyte marker 3G5 and show enhanced chondrogenesis after expansion in fibroblast growth factor-2
    Wasim S Khan
    Faculty of Life Sciences, United Kingdom Centre for Tissue Engineering at the Wellcome Trust Centre for Cell Matrix Research, Michael Smith Building, University of Manchester, Oxford Road, Manchester, UK
    Arthritis Res Ther 10:R74. 2008
    ..The effects of the expansion of these cells in fibroblast growth factor-2 (FGF-2) were tested on their proliferation, characterisation, and chondrogenic potential...
  20. doi The epitope characterisation and the osteogenic differentiation potential of human fat pad-derived stem cells is maintained with ageing in later life
    W S Khan
    United Kingdom Centre for Tissue Engineering and Wellcome Trust Centre for Cell Matrix Research, University of Manchester, Oxford Road, Manchester M13 9PT, UK
    Injury 40:150-7. 2009
    ..This has many potential therapeutic tissue engineering applications for the repair of bone defects in an increasingly ageing population...
  21. ncbi A modified technique of using the dynamic external finger fixation system. Case study
    Wasim S Khan
    University College London Institute of Orthopaedic and Musculoskeletal Sciences, Royal National Orthopaedic Hospital, Stanmore, Middlesex, HA7 4LP, UK
    Ortop Traumatol Rehabil 13:399-402. 2011
    ..The additional use of limited internal fixation ensured adequate fracture reduction and stabilisation. The S-Quattro application does not require significant soft tissue dissection, making it particularly suited to open fractures...
  22. ncbi Non-steroidal anti-inflammatory drugs in orthopaedic and perioperative practice
    Wasim Khan
    Academic Orthopaedic Registrar, University College London Institute of Orthopaedic and Musculoskeletal Research, Royal National Orthopaedic Hospital, Stanmore, Middlesex HA7 4LP, UK
    J Perioper Pract 19:287-90. 2009
    ..There is evidence suggesting that these drugs adversely affect bone formation, and this has implications for their use in patients with fractures and other pathologies that involve bone remodelling...
  23. doi The potential of stem cells in the treatment of knee cartilage defects
    Wasim S Khan
    UK Centre for Tissue Engineering, University of Manchester, Oxford Road, M13 9PL UK
    Knee 17:369-74. 2010
    ..A number of challenges however still need to be overcome including further work on identifying the optimal source of stem cells, along with refining the conditions that enhance expansion and chondrogenesis...
  24. doi Bone marrow-derived mesenchymal stem cells express the pericyte marker 3G5 in culture and show enhanced chondrogenesis in hypoxic conditions
    Wasim S Khan
    United Kingdom Centre for Tissue Engineering, Faculty of Life Sciences, University of Manchester, Manchester, United Kingdom
    J Orthop Res 28:834-40. 2010
    ..The response to chondrogenic culture in these cells was enhanced by lowered oxygen tension. This has important implications for tissue engineering applications of bone marrow-derived stem cells...
  25. ncbi Repair of distal biceps tendon rupture with the Biotenodesis screw
    W Khan
    Department of Orthopaedics and Trauma, Hope Hospital, Stott Lane, M6 8HD, Salford, United Kingdom
    Arch Orthop Trauma Surg 124:206-8. 2004
    ..These injuries are commonly repaired using either a single anterior incision with suture anchors or the Boyd-Anderson dual incision technique...
  26. pmc The validity, reliability, responsiveness, and bias of the manchester-modified disability of the arm, shoulder, and hand score in hand injuries
    Wasim S Khan
    Faculty of Life Sciences, University of Manchester, Oxford Road, Manchester, M13 9PT, UK
    Hand (N Y) 4:362-7. 2009
    ..It is a valid and responsive questionnaire with test-retest reliability proven for hand injuries in this study. Gender, handedness, and side injured did not cause bias in the responses...
  27. ncbi Common fractures and injuries of the ankle and foot: functional anatomy, imaging, classification and management
    Wasim Khan
    UCL Institute of Orthopaedics, Royal Orthopaedic Hospital, Stanmore HA7 4LP
    J Perioper Pract 20:249-58. 2010
    ....
  28. pmc Hypoxic conditions increase hypoxia-inducible transcription factor 2alpha and enhance chondrogenesis in stem cells from the infrapatellar fat pad of osteoarthritis patients
    Wasim S Khan
    UK Centre for Tissue Engineering and Wellcome Trust Centre for Cell Matrix Research, Faculty of Life Sciences, Michael Smith Building, University of Manchester, Oxford Road, Manchester M13 9PT, UK
    Arthritis Res Ther 9:R55. 2007
    ..This has important implications for tissue engineering applications of cells derived from the IPFP...
  29. pmc Human meniscus cells express hypoxia inducible factor-1alpha and increased SOX9 in response to low oxygen tension in cell aggregate culture
    Adetola B Adesida
    UK Centre for Tissue Engineering, Faculty of Life Sciences, The University of Manchester, Michael Smith Building, Oxford Road, Manchester, M13 9PT, UK
    Arthritis Res Ther 9:R69. 2007
    ..These results suggest that the vasculature and greater oxygen tension in the outer meniscus may help to suppress cartilage-like matrix formation...
  30. pmc The matrix-forming phenotype of cultured human meniscus cells is enhanced after culture with fibroblast growth factor 2 and is further stimulated by hypoxia
    Adetola B Adesida
    UK Centre for Tissue Engineering at The Wellcome Trust Centre for Cell Matrix Research, Faculty of Life Sciences, Michael Smith Building, The University of Manchester, Manchester, Oxford Road, M13 9PT, UK
    Arthritis Res Ther 8:R61. 2006
    ..Meniscus cells after expansion in monolayer can therefore respond to chondrogenic signals, and this is enhanced by FGF2 during expansion and low oxygen tension during aggregate cultures...
  31. ncbi Delayed open reduction and internal fixation of a neglected fracture dislocation of the ankle
    W S Khan
    Department of Orthopaedics and Trauma, Stepping Hill Hospital, Stockport, UK
    Int J Clin Pract 61:594-5. 2007
    ..It is important to preserve as much soft tissue attachments and periosteum to prevent avascular necrosis...
  32. pmc Ilizarov principles of deformity correction
    B Spiegelberg
    University College London Institute of Orthopaedics and Musculoskeletal Sciences, Royal National Orthopaedic Hospital, Stanmore, Middlesex, UK
    Ann R Coll Surg Engl 92:101-5. 2010
    ..In this review article, the history of Ilizarov frame, the basic sciences behind it, the mechanical principles governing its use and the clinical use of the fixation system are discussed...
  33. pmc The potential of stem cells in the treatment of skeletal muscle injury and disease
    S Maclean
    University of Manchester, Manchester M13 9PL, UK
    Stem Cells Int 2012:282348. 2012
    ..Although no doubt, stem cells will have much to offer in the future, the results of further research still limit their use...