Jane Achan

Summary

Country: UK

Publications

  1. pmc Effectiveness of quinine versus artemether-lumefantrine for treating uncomplicated falciparum malaria in Ugandan children: randomised trial
    Jane Achan
    Makerere University School of Health Sciences, PO Box 7475, Kampala, Uganda
    BMJ 339:b2763. 2009
  2. pmc Antiretroviral agents and prevention of malaria in HIV-infected Ugandan children
    Jane Achan
    Department of Pediatrics and Child Health, Makerere University College of Health Sciences, Kampala, Uganda
    N Engl J Med 367:2110-8. 2012
  3. pmc Effect of trimethoprim-sulphamethoxazole on the risk of malaria in HIV-infected Ugandan children living in an area of widespread antifolate resistance
    Anne F Gasasira
    School of Medicine, Makerere University Kampala, Uganda
    Malar J 9:177. 2010
  4. pmc Placental malaria among HIV-infected and uninfected women receiving anti-folates in a high transmission area of Uganda
    Patrick M Newman
    School of Medicine, University of California, San Francisco, 513 Parnassus Ave, San Francisco, CA 94131, USA
    Malar J 8:254. 2009
  5. pmc Quinine, an old anti-malarial drug in a modern world: role in the treatment of malaria
    Jane Achan
    Department of Pediatrics and Child Health, Makerere University College of Health Sciences, P O Box 7475, Kampala, Uganda
    Malar J 10:144. 2011
  6. pmc Case management of severe malaria--a forgotten practice: experiences from health facilities in Uganda
    Jane Achan
    Department of Paediatrics and Child Health, Makerere University College of Health Sciences, Kampala, Uganda
    PLoS ONE 6:e17053. 2011
  7. pmc Prevalence of asymptomatic parasitemia and gametocytemia among HIV-infected Ugandan children randomized to receive different antiretroviral therapies
    Gloria Ikilezi
    Infectious Diseases Research Collaboration, Kampala, Uganda
    Am J Trop Med Hyg 88:744-6. 2013
  8. doi request reprint High risk of neutropenia in HIV-infected children following treatment with artesunate plus amodiaquine for uncomplicated malaria in Uganda
    Anne F Gasasira
    Department of Internal Medicine, Makerere University, Mulago Hospital, Kampala, Uganda
    Clin Infect Dis 46:985-91. 2008
  9. pmc Parasite-based malaria diagnosis: are health systems in Uganda equipped enough to implement the policy?
    Daniel J Kyabayinze
    Malaria Consortium, Upper Naguru East Road, P, O, Box 8045, Kampala, Uganda
    BMC Public Health 12:695. 2012
  10. pmc Efficacy of quinine, artemether-lumefantrine and dihydroartemisinin-piperaquine as rescue treatment for uncomplicated malaria in Ugandan children
    Adoke Yeka
    Uganda Malaria Surveillance Project, Kampala, Uganda
    PLoS ONE 8:e53772. 2013

Collaborators

Detail Information

Publications15

  1. pmc Effectiveness of quinine versus artemether-lumefantrine for treating uncomplicated falciparum malaria in Ugandan children: randomised trial
    Jane Achan
    Makerere University School of Health Sciences, PO Box 7475, Kampala, Uganda
    BMJ 339:b2763. 2009
    ..To compare the effectiveness of oral quinine with that of artemether-lumefantrine in treating uncomplicated malaria in children...
  2. pmc Antiretroviral agents and prevention of malaria in HIV-infected Ugandan children
    Jane Achan
    Department of Pediatrics and Child Health, Makerere University College of Health Sciences, Kampala, Uganda
    N Engl J Med 367:2110-8. 2012
    ....
  3. pmc Effect of trimethoprim-sulphamethoxazole on the risk of malaria in HIV-infected Ugandan children living in an area of widespread antifolate resistance
    Anne F Gasasira
    School of Medicine, Makerere University Kampala, Uganda
    Malar J 9:177. 2010
    ..This study assessed the incidence of falciparum malaria and the prevalence of resistance-conferring Plasmodium falciparum mutations in HIV-infected children receiving daily TS and HIV-uninfected children not taking TS...
  4. pmc Placental malaria among HIV-infected and uninfected women receiving anti-folates in a high transmission area of Uganda
    Patrick M Newman
    School of Medicine, University of California, San Francisco, 513 Parnassus Ave, San Francisco, CA 94131, USA
    Malar J 8:254. 2009
    ..TS decreases the risk of malaria in HIV-infected adults and children but has not been evaluated among pregnant women...
  5. pmc Quinine, an old anti-malarial drug in a modern world: role in the treatment of malaria
    Jane Achan
    Department of Pediatrics and Child Health, Makerere University College of Health Sciences, P O Box 7475, Kampala, Uganda
    Malar J 10:144. 2011
    ..In HIV and TB infected populations, concerns about potential interactions between quinine and antiretroviral and anti-tuberculosis drugs exist, and these will need further research and pharmacovigilance...
  6. pmc Case management of severe malaria--a forgotten practice: experiences from health facilities in Uganda
    Jane Achan
    Department of Paediatrics and Child Health, Makerere University College of Health Sciences, Kampala, Uganda
    PLoS ONE 6:e17053. 2011
    ..There is paucity of published information on current practices of severe malaria case management in sub-Saharan Africa; we evaluated the management practices for severe malaria in Ugandan health facilities..
  7. pmc Prevalence of asymptomatic parasitemia and gametocytemia among HIV-infected Ugandan children randomized to receive different antiretroviral therapies
    Gloria Ikilezi
    Infectious Diseases Research Collaboration, Kampala, Uganda
    Am J Trop Med Hyg 88:744-6. 2013
    ..4% versus 6.5%, P = 0.04). Thus, in addition to decreasing the incidence of malaria, the use of PI-based ART may lower transmission, as a result of a decrease in gametocytemia, in areas of high malaria transmission intensity...
  8. doi request reprint High risk of neutropenia in HIV-infected children following treatment with artesunate plus amodiaquine for uncomplicated malaria in Uganda
    Anne F Gasasira
    Department of Internal Medicine, Makerere University, Mulago Hospital, Kampala, Uganda
    Clin Infect Dis 46:985-91. 2008
    ..Artemisinin-based combination therapies are rapidly being adopted for the treatment of malaria in Africa; however, there are limited data on their safety and efficacy among human immunodeficiency virus (HIV)-infected populations...
  9. pmc Parasite-based malaria diagnosis: are health systems in Uganda equipped enough to implement the policy?
    Daniel J Kyabayinze
    Malaria Consortium, Upper Naguru East Road, P, O, Box 8045, Kampala, Uganda
    BMC Public Health 12:695. 2012
    ..Effective coverage of parasite-based malaria diagnosis (PMD) remains limited in malaria endemic countries. This study assessed the health system's capacity to absorb PMD at primary health care facilities in Uganda...
  10. pmc Efficacy of quinine, artemether-lumefantrine and dihydroartemisinin-piperaquine as rescue treatment for uncomplicated malaria in Ugandan children
    Adoke Yeka
    Uganda Malaria Surveillance Project, Kampala, Uganda
    PLoS ONE 8:e53772. 2013
    ..Moreover, such practice goes against the World Health Organisation (WHO) recommendation to use combination therapy for uncomplicated malaria...
  11. pmc Malaria in Uganda: challenges to control on the long road to elimination: I. Epidemiology and current control efforts
    Adoke Yeka
    Infectious Diseases Research Collaboration, Kampala, Uganda
    Acta Trop 121:184-95. 2012
    ..Despite these challenges, prospects for the control of malaria have improved, and with attention to underlying challenges, progress toward the control of malaria in Uganda can be expected...
  12. doi request reprint Quinine monotherapy for treating uncomplicated malaria in the era of artemisinin-based combination therapy: an appropriate public health policy?
    Adoke Yeka
    Uganda Malaria Surveillance Project, Kampala, Uganda
    Lancet Infect Dis 9:448-52. 2009
    ....
  13. ncbi request reprint Effects of trimethoprim-sulfamethoxazole and insecticide-treated bednets on malaria among HIV-infected Ugandan children
    Moses R Kamya
    Makerere University Medical School, Kampala, Uganda
    AIDS 21:2059-66. 2007
    ..The efficacy of TMP/SMX may be diminished where antifolate resistance to malaria is high. We evaluated the efficacy of these interventions for malaria prevention among Ugandan children...
  14. ncbi request reprint Profile of T cell immune responses in HIV-infected children from Uganda
    Isaac Ssewanyana
    Joint Clinical Research Centre, Kampala, Uganda
    J Infect Dis 196:1667-70. 2007
    ..Understanding the balance between immune activation and T cell immunity in HIV-infected children may provide further insights into the mechanisms leading to effective immune control...
  15. ncbi request reprint Rectal versus intravenous quinine for the treatment of childhood cerebral malaria in Kampala, Uganda: a randomized, double-blind clinical trial
    Jane Achan
    Department of Pediatrics and Child Health, Makerere University, Kampala, Uganda
    Clin Infect Dis 45:1446-52. 2007
    ..We compared the efficacy and safety of intrarectal quinine with those of intravenous quinine in the treatment of childhood cerebral malaria...