Research Topics

Genomes and Genes

Species

ROSALIE MARIE UHT

Summary

Publications

  1. Bhave S, Uht R. CpG methylation and the methyl CpG binding protein 2 (MeCP2) are required for restraining corticotropin releasing hormone (CRH) gene expression. Mol Cell Endocrinol. 2017;454:158-164 pubmed publisher
    ..Taken together, the results indicate that site-specific methylation and MeCP2 are required for maintenance of basal levels of CRH gene expression. ..
  2. Sharma D, Liu Y, Uht R. Estradiol (E2)- and tamoxifen (Tmx)-bound ER-alpha (ER?) interact differentially with histone deacetylases 1 and 3 (HDACs 1 and 3). J Steroid Biochem Mol Biol. 2017;174:128-132 pubmed publisher
    ..In distinction, only HDAC3 knock-down led to increased activity in the presence of Tmx. In summary, ER? differentially interacts with HDACs 1 and 3 to regulate transcriptional activity. ..