K Tziomalos

Summary

Publications

  1. ncbi request reprint Treatment of beta-thalassaemia-associated osteoporosis with zoledronic acid
    Vasilios Perifanis
    Br J Haematol 125:91-2; author reply 93-4. 2004
  2. doi request reprint Impaired fasting glucose in hypertensive patients: prevalence and cross-sectional analysis of associations with cardiovascular disease
    Konstantinos Tziomalos
    First Propedeutic Department of Internal Medicine, Medical School, Aristotle University of Thessaloniki, AHEPA Hospital, Thessaloniki, Greece
    Diabetes Technol Ther 15:475-80. 2013
  3. ncbi request reprint Hydrochlorothiazide vs. chlorthalidone as the optimal diuretic for the management of hypertension
    Konstantinos Tziomalos
    First Propedeutic Department of Internal Medicine, AHEPA Hospital, 1 Stilponos Kyriakidi Street, 546 36 Thessaloniki, Greece
    Curr Pharm Des 19:3766-72. 2013
  4. ncbi request reprint Colesevelam: a new and improved bile acid sequestrant?
    Konstantinos Tziomalos
    First Propedeutic Department of Internal Medicine, Medical School, Aristotle University of Thessaloniki, AHEPA Hospital, Thessaloniki, Greece
    Curr Pharm Des 19:3115-23. 2013
  5. doi request reprint Comparison of markers of insulin resistance and circulating androgens between women with polycystic ovary syndrome and women with metabolic syndrome
    Konstantinos Tziomalos
    First Propedeutic Department of Internal Medicine, Aristotle University of Thessaloniki, AHEPA Hospital, Thessaloniki, Greece
    Hum Reprod 28:785-93. 2013
  6. doi request reprint Adipokines, insulin resistance and hyperandrogenemia in obese patients with polycystic ovary syndrome: cross-sectional correlations and the effects of weight loss
    Nikolaos Spanos
    Division of Endocrinology and Human Reproduction, Second Department of Obstetrics and Gynecology, Hippokration Hospital, Thessaloniki, Greece
    Obes Facts 5:495-504. 2012
  7. ncbi request reprint Non-alcoholic fatty liver disease in type 2 diabetes: pathogenesis and treatment options
    Konstantinos Tziomalos
    First Propedeutic Department of Internal Medicine, AHEPA Hospital, Thessaloniki, Greece
    Curr Vasc Pharmacol 10:162-72. 2012
  8. pmc The effects of obesity and polycystic ovary syndrome on serum lipocalin-2 levels: a cross-sectional study
    Dimitrios Panidis
    Division of Endocrinology and Human Reproduction, Second Department of Obstetrics and Gynecology, Aristotle University of Thessaloniki, Hippokration Hospital, Thessaloniki, Greece
    Reprod Biol Endocrinol 8:151. 2010
  9. pmc Treatment of congenital fibrinogen deficiency: overview and recent findings
    Konstantinos Tziomalos
    Second Propedeutic Department of Internal Medicine, Medical School, Aristotle University of Thessaloniki, Hippokration Hospital, Thessaloniki, Greece
    Vasc Health Risk Manag 5:843-8. 2009
  10. ncbi request reprint Omega-3 fatty acids: how can they be used in secondary prevention?
    Konstantinos Tziomalos
    Second Propedeutic Department of Internal Medicine, Aristotle University, Hippokration Hospital, 63 Solonos Street, Thessaloniki, 54248, Greece
    Curr Atheroscler Rep 10:510-7. 2008

Collaborators

Detail Information

Publications47

  1. ncbi request reprint Treatment of beta-thalassaemia-associated osteoporosis with zoledronic acid
    Vasilios Perifanis
    Br J Haematol 125:91-2; author reply 93-4. 2004
  2. doi request reprint Impaired fasting glucose in hypertensive patients: prevalence and cross-sectional analysis of associations with cardiovascular disease
    Konstantinos Tziomalos
    First Propedeutic Department of Internal Medicine, Medical School, Aristotle University of Thessaloniki, AHEPA Hospital, Thessaloniki, Greece
    Diabetes Technol Ther 15:475-80. 2013
    ..However, it is unclear whether IFG is associated with increased cardiovascular risk in this population...
  3. ncbi request reprint Hydrochlorothiazide vs. chlorthalidone as the optimal diuretic for the management of hypertension
    Konstantinos Tziomalos
    First Propedeutic Department of Internal Medicine, AHEPA Hospital, 1 Stilponos Kyriakidi Street, 546 36 Thessaloniki, Greece
    Curr Pharm Des 19:3766-72. 2013
    ..However, current guidelines do not consistently recommend one or the other and it remains to be established which one is the diuretic of choice...
  4. ncbi request reprint Colesevelam: a new and improved bile acid sequestrant?
    Konstantinos Tziomalos
    First Propedeutic Department of Internal Medicine, Medical School, Aristotle University of Thessaloniki, AHEPA Hospital, Thessaloniki, Greece
    Curr Pharm Des 19:3115-23. 2013
    ..Therefore, colesevelam seems to be a useful tool for the management of high-risk patients who cannot achieve LDL-C targets with monotherapy with a potent statin...
  5. doi request reprint Comparison of markers of insulin resistance and circulating androgens between women with polycystic ovary syndrome and women with metabolic syndrome
    Konstantinos Tziomalos
    First Propedeutic Department of Internal Medicine, Aristotle University of Thessaloniki, AHEPA Hospital, Thessaloniki, Greece
    Hum Reprod 28:785-93. 2013
    ..Do women with the polycystic ovary syndrome (PCOS) differ from those with the metabolic syndrome (MetS) in markers of insulin resistance (IR) and circulating androgens?..
  6. doi request reprint Adipokines, insulin resistance and hyperandrogenemia in obese patients with polycystic ovary syndrome: cross-sectional correlations and the effects of weight loss
    Nikolaos Spanos
    Division of Endocrinology and Human Reproduction, Second Department of Obstetrics and Gynecology, Hippokration Hospital, Thessaloniki, Greece
    Obes Facts 5:495-504. 2012
    ..To assess the effects of weight loss on serum adipokine levels in polycystic ovary syndrome (PCOS)...
  7. ncbi request reprint Non-alcoholic fatty liver disease in type 2 diabetes: pathogenesis and treatment options
    Konstantinos Tziomalos
    First Propedeutic Department of Internal Medicine, AHEPA Hospital, Thessaloniki, Greece
    Curr Vasc Pharmacol 10:162-72. 2012
    ..Accordingly, prevention of obesity and T2DM is of paramount importance for the reduction of the prevalence of NAFLD and of its associated cardiovascular and liver-related complications...
  8. pmc The effects of obesity and polycystic ovary syndrome on serum lipocalin-2 levels: a cross-sectional study
    Dimitrios Panidis
    Division of Endocrinology and Human Reproduction, Second Department of Obstetrics and Gynecology, Aristotle University of Thessaloniki, Hippokration Hospital, Thessaloniki, Greece
    Reprod Biol Endocrinol 8:151. 2010
    ..However, there are limited data on serum lipocalin-2 levels in patients with PCOS. The aim of the present study was to assess serum lipocalin-2 levels in PCOS...
  9. pmc Treatment of congenital fibrinogen deficiency: overview and recent findings
    Konstantinos Tziomalos
    Second Propedeutic Department of Internal Medicine, Medical School, Aristotle University of Thessaloniki, Hippokration Hospital, Thessaloniki, Greece
    Vasc Health Risk Manag 5:843-8. 2009
    ..The development of new tests to identify higher risk patients and of safer replacement therapy will improve the management of afibrinogenemia in the future...
  10. ncbi request reprint Omega-3 fatty acids: how can they be used in secondary prevention?
    Konstantinos Tziomalos
    Second Propedeutic Department of Internal Medicine, Aristotle University, Hippokration Hospital, 63 Solonos Street, Thessaloniki, 54248, Greece
    Curr Atheroscler Rep 10:510-7. 2008
    ..Increased intake of EPA and DHA represents a valuable tool for vascular disease prevention and should be recommended in all patients with CHD...
  11. pmc Effects of lifestyle measures, antiobesity agents, and bariatric surgery on serological markers of inflammation in obese patients
    Konstantinos Tziomalos
    First Propedeutic Department of Internal Medicine, Medical School, Aristotle University of Thessaloniki, AHEPA Hospital, 54646, Thessaloniki, Greece
    Mediators Inflamm 2010:364957. 2010
    ....
  12. ncbi request reprint Persistent effect of zoledronic acid in Paget's disease
    K Tziomalos
    2nd Propedeutic Department of Internal Medicine, Aristotle University of Thessaloniki, Hippokration Hospital, Thessaloniki, Greece
    Clin Exp Rheumatol 25:464-6. 2007
    ..In conclusion, zoledronic acid, apart from being safe and effective in Paget's disease, also appears to be able to achieve significantly prolonged remissions...
  13. ncbi request reprint Management of acute bleeding in a patient with congenital afibrinogenaemia
    S Vakalopoulou
    Haematology Section of Second Propedeutic, Department of Internal Medicine, Aristotle University of Thessaloniki, Hippokration Hospital, Thessaloniki, Greece
    Haemophilia 12:676-8. 2006
    ..The efficacy of this treatment and the problems that arose during his hospitalization are being discussed...
  14. ncbi request reprint Mitral valve reconstruction in a compound heterozygote for sickle cell anemia and hemoglobin Lepore
    Konstantinos Tziomalos
    Second Propaedeutic Department of Internal Medicine, Aristotle University of Thessaloniki, Hippokration Hospital, Greece
    J Thorac Cardiovasc Surg 130:932-3. 2005
  15. ncbi request reprint Endocrine effects of tobacco smoking
    Konstantinos Tziomalos
    Division of Endocrinology, 2nd Propedeutic Department of Internal Medicine, Aristotle University of Thessaloniki, Hippokration General Hospital, Thessaloniki, Greece
    Clin Endocrinol (Oxf) 61:664-74. 2004
  16. doi request reprint Effect of a plant stanol ester-containing spread, placebo spread, or Mediterranean diet on estimated cardiovascular risk and lipid, inflammatory and haemostatic factors
    V G Athyros
    Atherosclerosis and Metabolic Syndrome Units, 2nd Propedeutic Department of Internal Medicine, Aristotelian University, Hippocration Hospital, 49 Konstantinoupoleos St, Thessaloniki 546 42, Greece
    Nutr Metab Cardiovasc Dis 21:213-21. 2011
    ..Use of plant stanols decreases low density lipoprotein cholesterol (LDL-C) concentrations. We compared the effects of the Mediterranean diet and plant stanol esters on vascular risk factors and estimated CVD (eCVD) risk...
  17. doi request reprint Cardiovascular benefits of bariatric surgery in morbidly obese patients
    V G Athyros
    Second Propedeutic Department of Internal Medicine, Aristotelian University, Hippocration Hospital, Thessaloniki, Greece
    Obes Rev 12:515-24. 2011
    ..Operation-associated mortality rates after bariatric surgery are low and LAGB is safer than LRYGB. In morbidly obese patients bariatric surgery is safe and appears to reduce cardiovascular morbidity and mortality...
  18. doi request reprint Implementation of strategy for the management of overt dyslipidemia: the IMPROVE-dyslipidemia study
    A I Hatzitolios
    1st Propedeutic Department of Internal Medicine, Aristotelian University, AHEPA Hospital, Thessaloniki, Greece
    Int J Cardiol 134:322-9. 2009
    ..To assess the efficacy of a strategy aimed at improving vascular risk management in patients with dyslipidemia with or without cardiovascular disease (CVD)...
  19. doi request reprint Cardiovascular risk factors and estimated 10-year risk of fatal cardiovascular events using various equations in Greeks with metabolic syndrome
    Theodoros Chimonas
    Department of Internal Medicine, Medical School, University of Ioannina, Ioannina, Greece
    Angiology 61:49-57. 2010
    ..This might justify local risk engine evaluation in event-based studies. (Clinical-Trials.gov ID: NCT00416741)...
  20. doi request reprint Brain natriuretic peptide and the athlete's heart: a pilot study
    E D Pagourelias
    Second Propedeutic Department of Internal Medicine, Medical School, Aristotle University of Thessaloniki, Hippokration Hospital, Thessaloniki, Greece
    Int J Clin Pract 64:511-7. 2010
    ..The role of brain natriuretic peptide (BNP) in differentiating the athlete's heart from maladaptive cardiac hypertrophy is unclear...
  21. doi request reprint Atherosclerosis and osteoporosis: age-dependent degenerative processes or related entities?
    P Anagnostis
    Second Propedeutic Department of Internal Medicine, Medical School, Aristotle University of Thessaloniki, Hippokration Hospital, Greece
    Osteoporos Int 20:197-207. 2009
    ..This review considers a potential link between osteoporosis and atherosclerosis beyond aging. These common factors may lead to appropriate treatment strategies...
  22. doi request reprint Neuropeptide Y and alpha-melanocyte-stimulating hormone: interaction in obesity and possible role in the development of hypertension
    M Baltatzi
    1st Propedeutic Medical Department, AXEPA Hospital, Aristotles University of Thessaloniki, Thessaloniki, Greece
    Int J Clin Pract 62:1432-40. 2008
    ..More specifically, leptin, neuropeptide Y (NPY) and alpha-melanocyte-stimulating hormone (a-MSH) appear to be implicated in the pathogenesis of obesity and also contribute to the development of hypertension in obesity...
  23. ncbi request reprint Effects of buflomedil on skin blood flow in patients with type 2 diabetes mellitus without overt micro- or macroangiopathy
    D Tsantilas
    Department of Internal Medicine, Georgios Gennimatas General Hospital, Thessaloniki, Greece
    Int Angiol 30:164-71. 2011
    ..The aim of this study was to assess the effects of buflomedil on the peripheral microcirculation in patients with type 2 diabetes mellitus (T2DM) without overt micro- or macroangiopathy...
  24. doi request reprint Initiative for a new diabetes therapeutic approach in a Mediterranean country: the INDEED study
    V G Athyros
    Atherosclerosis and Metabolic Syndrome Units, 2nd Propedeutic Department of Internal Medicine, Aristotelian University, Hippocration Hospital, Thessaloniki, Greece
    Curr Med Res Opin 25:1931-40. 2009
    ..To assess the efficacy of a strategy to improve vascular risk management in patients with type 2 diabetes mellitus (T2DM)...
  25. ncbi request reprint Standardized arrangement for a guideline-driven treatment of the metabolic syndrome: the SAGE-METS study
    V G Athyros
    Atherosclerosis and Metabolic Syndrome Units, 2nd Propedeutic Department of Internal Medicine, Aristotelian University, Hippocration Hospital, Thessaloniki, Greece
    Curr Med Res Opin 25:971-80. 2009
    ..To substantially increase awareness, treatment and effective control of the metabolic syndrome (MetS) and its components...
  26. ncbi request reprint Buflomedil: potential new indications for an old agent
    D Tsantilas
    Department of Internal Medicine, Georgios Gennimatas Hospital, Thessaloniki, Greece
    Int Angiol 28:170-4. 2009
    ..However, it remains to be established whether these drugs could also be beneficial in the diabetic population, especially in the early stages of diabetes...
  27. ncbi request reprint The unilateral measurement of blood pressure may mask the diagnosis or delay the effective treatment of hypertension
    Asterios Karagiannis
    Second Propedeutic Department of Internal Medicine, Aristotle University of Thessaloniki, Hippokration Hospital, Thessaloniki, Greece
    Angiology 56:565-9. 2005
    ..It is thus recommended that BP should be simultaneously measured in both arms at the initial consultation and the higher of the 2 readings should be used to guide further management decisions...
  28. ncbi request reprint Effect of zoledronic acid on markers of bone turnover and mineral density in osteoporotic patients with beta-thalassaemia
    Vassilios Perifanis
    Thalassaemia Unit, Aristotle University of Thessaloniki, Hippokration General Hospital, Thessaloniki, Greece
    Ann Hematol 86:23-30. 2007
    ..Our study supports the effectiveness of bisphosphonates in the treatment of thalassemia-induced osteoporosis...
  29. ncbi request reprint Short-term administration of orlistat reduced daytime triglyceridemia in obese women with the metabolic syndrome
    Themistoklis Tzotzas
    Department of Endocrinology, Diabetes and Metabolism, Panagia General Hospital, Thessaloniki, Greece
    Angiology 58:26-33. 2007
    ..This reduction could offer cardiovascular benefits in these high-risk patients. Long-term studies with more patients are needed to reach definite conclusions...
  30. doi request reprint Coagulation and inflammation biomarkers may help predict the severity of community-acquired pneumonia
    Dimitrios I Agapakis
    First Propedeutic Department of Internal Medicine, Aristotle University of Thessaloniki, Hospital AHEPA, Thessaloniki, Greece
    Respirology 15:796-803. 2010
    ..The aim of this study was to evaluate the association between the severity of CAP and serum levels of antithrombin III (AT-III), protein C (P-C), D-dimers (D-D) and CRP, at hospital admission...
  31. ncbi request reprint Should adipokines be considered in the choice of the treatment of obesity-related health problems?
    Vasilios G Athyros
    Second Propedeutic Department of Internal Medicine, Aristotle University, Hippokration Hospital, Thessaloniki, Greece
    Curr Drug Targets 11:122-35. 2010
    ..Moreover, it summarises treatment options for the normalisation of adipokine levels, which might confer an additional clinical benefit in the effort to prevent or treat obesity-related T2DM and CVD...
  32. doi request reprint Effects of statin treatment in men and women with stable coronary heart disease: a subgroup analysis of the GREACE Study
    Vasilios G Athyros
    Atherosclerosis and Metabolic Syndrome Units, Second Propedeutic Department of Internal Medicine, Aristotelian University, Hippocration Hospital, Thessaloniki, Greece
    Curr Med Res Opin 24:1593-9. 2008
    ..Reducing low-density lipoprotein cholesterol (LDL-C) levels to National Cholesterol Expert Panel (NCEP) goal is recommended. However, sex-specific effects may influence benefit...
  33. pmc The use of sibutramine in the management of obesity and related disorders: an update
    Konstantinos Tziomalos
    Department of Endocrinology, Diabetes and Metabolism, Panagia General Hospital, Thessaloniki, Greece
    Vasc Health Risk Manag 5:441-52. 2009
    ..To review the major trials that evaluated the efficacy and safety of the use of sibutramine for weight loss and the impact of this agent on obesity-related disorders...
  34. ncbi request reprint Atorvastatin decreases triacylglycerol-associated risk of vascular events in coronary heart disease patients
    Vasilios G Athyros
    Atherosclerosis and Metabolic Syndrome Units, 2nd Propedeutic Department of Internal Medicine, Aristotelian University, Hippocration Hospital, Thessaloniki, Greece
    Lipids 42:999-1009. 2007
    ..Statin (mainly atorvastatin)-induced decrease in TAG levels was related to a significant reduction in subsequent CVD events. This benefit was more pronounced in CHD MetS (+) patients...
  35. ncbi request reprint Effect of statin treatment on renal function and serum uric acid levels and their relation to vascular events in patients with coronary heart disease and metabolic syndrome: a subgroup analysis of the GREek Atorvastatin and Coronary heart disease Evaluati
    Vasilios G Athyros
    FASA, FRSH, Department of Internal Medicine, Medical School, University of Ioannina, 451 10 Ioannina, Greece
    Nephrol Dial Transplant 22:118-27. 2007
    ..Metabolic syndrome (MetS) is associated with increased risk for both vascular and chronic kidney disease. Whether statins ameliorate these risks is not established...
  36. doi request reprint Prevalence, bowel habit subtypes and medical care-seeking behaviour of patients with irritable bowel syndrome in Northern Greece
    Panagiotis Katsinelos
    Department of Endoscopy and Motility Unit, Central Hospital, Thessaloniki, Greece
    Eur J Gastroenterol Hepatol 21:183-9. 2009
    ....
  37. ncbi request reprint Elevated levels of serum vascular endothelial growth factor in patients with polycythaemia vera
    Stamatia Theodoridou
    Second Propedeutic Department of Internal Medicine, Aristotelion University of Thessaloniki, Thessaloniki, Greece
    Acta Haematol 110:16-9. 2003
    ..Our results indicate that VEGF is overproduced in PV. However, follow-up studies are needed to verify the role of this factor...
  38. doi request reprint Safety and efficacy of long-term statin treatment for cardiovascular events in patients with coronary heart disease and abnormal liver tests in the Greek Atorvastatin and Coronary Heart Disease Evaluation (GREACE) Study: a post-hoc analysis
    Vasilios G Athyros
    Second Propedeutic Department of Internal Medicine, Medical School, Aristotle University of Thessaloniki, Hippokration Hospital, Thessaloniki, Greece
    Lancet 376:1916-22. 2010
    ..We assessed whether statin therapy is safe and effective for these patients through post-hoc analysis of the Greek Atorvastatin and Coronary Heart Disease Evaluation (GREACE) study population...
  39. ncbi request reprint Pleiotropic effects of statins--clinical evidence
    Vasilios G Athyros
    Second Propedeutic Department of Internal Medicine, Medical School, Aristotle University of Thessaloniki, HippocrationHospital, Thessaloniki, Greece
    Curr Pharm Des 15:479-89. 2009
    ....
  40. ncbi request reprint Association of drinking pattern and alcohol beverage type with the prevalence of metabolic syndrome, diabetes, coronary heart disease, stroke, and peripheral arterial disease in a Mediterranean cohort
    Vasilios G Athyros
    Atherosclerosis and Metabolic Syndrome Units, Aristotelean University, Hippocration Hospital, Thessaloniki, Greece
    Angiology 58:689-97. 2007
    ..Heavy drinking was associated with an increase in the prevalence of all of these disease states. Advice on alcohol consumption should probably mainly aim at reducing heavy drinking...
  41. doi request reprint Effectiveness of ezetimibe alone or in combination with twice a week Atorvastatin (10 mg) for statin intolerant high-risk patients
    Vasilios G Athyros
    Second Propedeutic Department of Internal Medicine, Medical School, Aristotle University of Thessaloniki, Hippocration Hospital, Thessaloniki, Greece
    Am J Cardiol 101:483-5. 2008
    ..In conclusion, the combination of ezetimibe plus atorvastatin 10 mg twice a week might be a therapeutic option for high-risk patients intolerant to daily statin monotherapy...
  42. doi request reprint Adefovir plus lamivudine are more effective than adefovir alone in lamivudine-resistant HBeAg- chronic hepatitis B patients: a 4-year study
    Themistoklis G Vassiliadis
    Gastroenterology and Hepatology Division, Second Propedeutic Department of Internal Medicine, Aristotle University of Thessaloniki, Hippokration Hospital, Thessaloniki, Greece
    J Gastroenterol Hepatol 25:54-60. 2010
    ..However, it is unclear whether LAM treatment should be continued in these patients. We aimed to compare the long-term efficacy of adding ADV to ongoing LAM treatment versus switching to ADV monotherapy in LAM-resistant HBeAg(-) CHB...
  43. ncbi request reprint Effect of multifactorial treatment on non-alcoholic fatty liver disease in metabolic syndrome: a randomised study
    Vasilios G Athyros
    Atherosclerosis and Metabolic Syndrome Units, Aristotelian University, Hippocration Hospital, Thessaloniki, Greece
    Curr Med Res Opin 22:873-83. 2006
    ..Non-alcoholic fatty liver disease (NAFLD) is the hepatic manifestation of the metabolic syndrome (MetS). There is no established treatment for NAFLD...
  44. ncbi request reprint Targeting vascular risk in patients with metabolic syndrome but without diabetes
    Vasilios G Athyros
    Atherosclerosis and Metabolic Syndrome Units, Aristotelian University, 55132 Thessaloniki, Greece
    Metabolism 54:1065-74. 2005
    ..Atorvastatin and combination treatment were more effective than fenofibrate alone in reducing CRP levels...
  45. ncbi request reprint Primary and secondary coronary heart disease prevention using statins: is targeting Adam or Eve equally effective?
    Anna I Kakafika
    Expert Opin Pharmacother 9:1437-40. 2008
    ..However, the relatively small number of women included in several statin trials has limited the evidence available. With regard to the question of whether Eve is becoming Adam, the answer is not yet: we need more evidence!..
  46. ncbi request reprint Eplerenone relieves spironolactone-induced painful gynaecomastia in a patient with primary aldosteronism
    Asterios Karagiannis
    Nephrol Dial Transplant 22:293. 2007
  47. doi request reprint Epidemiological survey for the prevalence of overweight and abdominal obesity in Greek adolescents
    Themistoklis Tzotzas
    Hellenic Medical Association for Obesity, Athens, Greece
    Obesity (Silver Spring) 16:1718-22. 2008
    ..AO, mainly in adolescent girls, also appears high. Preventive and treatment strategies are urgently needed to combat this OB epidemic in Greece...