- Large-scale identification and analysis of suppressive drug interactionsMurat Cokol
Biological Sciences and Bioengineering Program, Faculty of Engineering and Natural Sciences, Sabanci University, Istanbul 34956, Turkey Nanotechnology Research and Application Center, Sabanci University, Istanbul 34956, Turkey Electronic address
Chem Biol 21:541-51. 2014..We investigated potential explanations for suppressive drug interactions, including chemogenomic analysis, coaggregation, and pH effects, allowing us to explain the interaction tendencies of Bromopyruvate. ..
- Systematic exploration of synergistic drug pairsMurat Cokol
Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA, USA
Mol Syst Biol 7:544. 2011..While many drug synergies correspond to genetic interactions, the majority of drug synergies appear to result from non-specific promiscuous synergy...
- Drugs and their interactionsMurat Cokol
Sabanci University, Faculty of Engineering and Natural Sciences, Biological Sciences and Bioengineering Program, and Nanotechnology Research and Application Center, Istanbul 34956, Turkey
Curr Drug Discov Technol 10:106-13. 2013..A better understanding of drug interactions and their relationship to phenotypes offers hope in finding drug combinations that have high therapeutic values...