Research Topics
| Orhan SezginSummaryAffiliation: Mersin University Country: Turkey Publications
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Detail Information
Publications
Detection of point mutations on 23S rRNA of Helicobacter pylori and resistance to clarithromycin with PCR-RFLP in gastric biopsy specimens in Mersin, TurkeyOrhan Sezgin
Department of Gastroenterology, Mersin University School of Medicine, Mersin, Turkey
Turk J Gastroenterol 19:163-7. 2008..It may be that Helicobacter pylori has become resistant to antibiotics. Therefore, we aimed to determine the rate of resistance to clarithromycin in the province of Mersin...
Bismuth-based therapies for the first step eradication of Helicobacter pyloriOrhan Sezgin
Department of Gastroenterology, Mersin University, School of Medicine, Mersin, Turkey
Turk J Gastroenterol 17:90-3. 2006..pylori infection in Turkey. There is no effective eradication regimen for H. pylori in our country. We aimed to compare bismuth- based triple and quadruple treatments for eradication of H. pylori...
A pilot study evaluating sequential administration of a PPI-amoxicillin followed by a PPI-metronidazole-tetracycline in TurkeyOrhan Sezgin
Mersin University, School of Medicine, Department of Gastroenterology, Mersin, Turkey
Helicobacter 12:629-32. 2007..pylori. Therefore, we aimed to confirm efficacy of a new therapy scheme in the first-line H. pylori eradication...
Comparison of ranitidine bismuth citrate, tetracycline and metronidazole with ranitidine bismuth citrate and azithromycin for the eradication of Helicobacter pylori in patients resistant to PPI based triple therapyEngin Altintas
Department of Gastroenterology, Medical Faculty Hospital, Mersin University, Mersin, Turkey
Turk J Gastroenterol 15:90-3. 2004..We compared PPI, bismuth, tetracycline and metronidazole with ranitidine bismuth citrate, tetracycline and metronidazole in cases resistant to PPIs-based triple therapies...
Low efficacy rate of moxifloxacin-containing Helicobacter pylori eradication treatment: in an observational study in a Turkish populationOrhan Sezgin
Department of Gastroenterology, School of Medicine, Mersin University, Mersin, Turkey
Helicobacter 12:518-22. 2007..It may be due to an increased resistance of H. pylori to antibiotics. Therefore, we aimed to investigate the effectiveness of a new second-generation fluoroquinolone, moxifloxacin-containing triple therapy in H. pylori eradication...
Intralesional steroid injection in benign esophageal strictures resistant to bougie dilationEngin Altintas
Mersin University, School of Medicine, Division of Gastroenterology, Mersin, Turkey
J Gastroenterol Hepatol 19:1388-91. 2004..Some benign esophageal strictures are highly resistant to bougie dilation. The aim of this study was to determine whether intralesional steroid injection had additional benefit to Savary-Gilliard's bougie dilation therapy (SGBD)...
Comparison of two different treatment protocols in Helicobacter pylori eradicationIsilay Nadir
Department of Gastroenterology, Sivas Numune Hospital, and Department of Gastroenterology, Cumhuriyet University, School of Medicine, Sivas, Turkey
South Med J 104:102-5. 2011..The prevalence of Helicobacter pylori (H pylori) in Turkey is high and eradication rates are low. As a result, alternative treatment strategies are required...
[Determination of hepatitis B virus genotypes in chronic hepatitis B patients in Mersin province, Turkey]Gurol Emekdas
Mersin University Faculty of Medicine, Department of Medical Microbiology, Mersin, Turkey
Mikrobiyol Bul 46:432-45. 2012....
Ectopic opening of the common bile duct into various sites of the upper digestive tract: a case seriesOrhan Sezgin
Gastroenterology Department, Mersin University Medical Faculty, Mersin, Turkey
Gastrointest Endosc 72:198-203. 2010..Ectopic opening of the common bile duct (CBD) into the GI tract is an extremely rare congenital anomaly. The clinical implications and frequency of this anomaly are not clearly known...
Prevalence of celiac disease among dyspeptic patients: a community-based case-control studyEngin Altintas
Department of Gastroenterology, Mersin University, School of Medicine, Mersin, Turkey
Turk J Gastroenterol 19:81-4. 2008..To determine the relation between undiagnosed celiac disease and dyspepsia in the community...
Effects of seasonal variations on acute upper gastrointestinal bleeding and its etiologyOrhan Sezgin
Department of Gastroenterology, Mersin University, School of Medicine, Mersin
Turk J Gastroenterol 18:172-6. 2007..The aim of this study was to determine the causes and risk factors of acute upper gastrointestinal bleeding, a frequently encountered medical emergency, and to determine any relation in its frequency according to month or season...
Maastricht II treatment scheme and efficacy of different proton pump inhibitors in eradicating Helicobacter pyloriEngin Altintas
Department of Gastroenterology, Mersin University, Faculty of Medicine, Turkey
World J Gastroenterol 10:1656-8. 2004....
Hepatic alveolar echinococcosis: clinical and radiologic features and endoscopic managementOrhan Sezgin
Division of Gastroenterology, Mersin University Medical Faculty, Mersin, Turkey
J Clin Gastroenterol 39:160-7. 2005..While benzimidazole derivatives are used for the control of disease, endoscopic retrograde cholangiopancreatography is particularly effective in the biliary involvement, even in the late stage of disease...
Dydrogesterone-induced hepatitis and autoimmune hemolytic anemiaEngin Altintas
Division of Gastroenterology, School of Medicine, Mersin University, Mersin, Turkey
Turk J Gastroenterol 15:49-52. 2004..We describe a case of hepatitis and warm antibody hemolytic anemia due to dydrogesterone...
A case of Behçet's disease presenting with massive lower gastrointestinal bleedingEngin Altintas
Department of Gastroenterology, Mersin University, School of Medicine, Mersin, Turkey
Turk J Gastroenterol 20:57-61. 2009..Here, we report a case of Behçet's disease presenting with lower gastrointestinal bleeding, mesenteric arterial thrombosis and duodenal perforation...
Fasciola hepatica-induced acute pancreatitis: report of two cases and review of the literatureOrhan Sezgin
Department of Gastroenterology, Mersin University, School of Medicine, Mersin
Turk J Gastroenterol 21:183-7. 2010..A high index of suspicion, specific ultrasonographic findings and eosinophilia are very helpful in the diagnosis of the disease...
Sickle cell anemia connected with chronic intrahepatic cholestasis: a case reportEngin Altintas
Division of Gastroenterology, School of Medicine, Mersin University, Mersin, Turkey
Turk J Gastroenterol 14:215-8. 2003..The findings in this case suggest that therapeutic erythrocyte apheresis may benefit patients who have unusual complications of sickle cell disease, such as chronic intrahepatic cholestasis in the liver...
Effects of terlipressin on systolic pulmonary artery pressure of patients with liver cirrhosis: an echocardiographic assessmentEngin Altintas
Mersin Universitesi Tip Fakultesi Hastanesi Ic Hastaliklari A D, 33079 Mersin, Turkiye
World J Gastroenterol 10:2278-80. 2004..Portopulmonary hypertension is a serious complication of chronic liver disease. Our aim was to search into the effect of terlipressin on systolic pulmonary artery pressure among cirrhotic patients...
S-adenosylhomocysteine hydrolase, S-adenosylmethionine, S-adenosylhomocysteine: correlations with ribavirin induced anemiaEngin Altintas
Division of Gastroenterology, School of Medicine, Mersin University, Zeytinli Bahce Cad Eski Otogar Yani, 33079 Mersin, Turkey
Med Hypotheses 63:834-7. 2004....
Acute upper gastrointestinal bleeding due to metastatic lung cancer: an unusual caseEngin Altintas
Mersin Universitesi Tip Fakultesi Hastanesi, Ic Hastaliklari A D 33079 Mersin, Turkey
Yonsei Med J 47:276-7. 2006..A 55-year-old man with known metastatic lung adenocancer exhibited epigastric pain, hematemesis, and melena. A bleeding, ulcerated gastric metastasis was found and treated with endoscopic therapy and omeprazole...
[Detection of Helicobacter pylori and antimicrobial resistance in gastric biopsy specimens]Umut Cağdaş
Mersin University Faculty of Medicine, Department of Medical Microbiology, Mersin, Turkey
Mikrobiyol Bul 46:398-409. 2012..In the case of treatment failure, culture should be performed for antibiotic susceptibility testing of the isolate...
Is there a relation between irritable Bowel syndrome and urinary stone disease?Erim Erdem
Department of Urology, Mersin University, Faculty of Medicine, Mersin, Turkey
Dig Dis Sci 50:605-8. 2005..In the presence of gastrointestinal symptoms, a patient with a medical history of acute renal colic might be referred to a gastroenterologist...
Alverine citrate plus simethicone reduces cecal intubation time in colonoscopy - a randomized studyEngin Altintas
Department of Gastroenterology, Mersin University, School of Medicine, Mersin, Turkey
Turk J Gastroenterol 19:174-9. 2008..The aim of this study was to determine the effects of alverine citrate plus simethicone on the cecal intubation time, colonic spasm and bowel cleanliness...
Ectopic opening of the common bile duct into the stomachOrhan Sezgin
Department of Gastroenterology, Mersin University, School of Medicine, Mersin
Turk J Gastroenterol 21:163-7. 2010....
An unusual cause for massive upper gastrointestinal bleeding in children: Dieulafoy's lesionDincer Avlan
Department of Pediatric Surgery, Mersin University, School of Medicine, Zeytinlibahce, Mersin, 33070, Turkey
Pediatr Surg Int 21:417-8. 2005..We report a case of massive upper gastrointestinal bleeding in a 3-year-old boy that originated from a Dieulafoy's lesion and was treated by epinephrine injection...
Initial presentation of hepatocellular carcinoma as a subcutaneous mass on the anterior chest wallEngin Altintas
Division of Gastroenterology, Mersin University, School of Medicine, Mersin, Turkey
Dig Dis Sci 49:651-2. 2004
Safety of peginterferon alfa-2a (40KD) treatment in patients with chronic hepatitis B infection: an observational, multicenter, open label, non-interventional study in Turkish patientsNurdan Tozun
Department of Gastroenterology, Acibadem University, Acibadem Kozyatagi Hospital, Kozyatagi, Istanbul, Turkey
Turk J Gastroenterol 23:552-9. 2012..Pegylated alfa interferon is the only immunomodulatory drug licensed for hepatitis B. We evaluated the safety and tolerability of peginterferon alfa-2a (40KD) in patients with chronic hepatitis B...
Watermelon colon: is there an association with alcohol?Engin Altintas
Department of Gastroenterology, Mersin University, School of Medicine, Mersin, Turkey
Med Sci Monit 13:CS137-140. 2007..Watermelon colon, or rectal vascular ectasia of the colon, is a very rare vascular lesion...
Esophageal variceal ligation for acute variceal bleeding: results of three years' follow-upEngin Altintas
Division of Gastroenterology, School of Medicine, Mersin University, Mersin, Turkey
Turk J Gastroenterol 15:27-33. 2004..However, the rebleeding course and long-term outcome of patients with esophageal variceal hemorrhage after ligation have been poorly defined. Therefore, we conducted a long-term follow-up study to delineate the outcome of ligation...
Long-term red blood cell exchange can be used to successfully treat sickle cell intrahepatic cholestasis: a case reportNaci Tiftik
Department of Hematology, Mersin University Medical School, Mersin, Turkey
J Clin Apher 19:17-9. 2004
Hepatobiliary fascioliasis: clinical and radiologic features and endoscopic managementOrhan Sezgin
Mersin University Medical Faculty, Gastroenterology Department, Mersin, Turkey
J Clin Gastroenterol 38:285-91. 2004..The disease has 2 stages: hepatic stage and biliary stage. While several drugs are used during the hepatic stage, endoscopic retrograde cholangiopancreatography is particularly effective in the biliary stage...
