Cory D Dunn

Summary

Affiliation: Koc University
Country: Turkey

Publications

  1. doi request reprint Running on empty: does mitochondrial DNA mutation limit replicative lifespan in yeast?: Mutations that increase the division rate of cells lacking mitochondrial DNA also extend replicative lifespan in Saccharomyces cerevisiae
    Cory D Dunn
    Department of Molecular Biology and Genetics, Koc University, Istanbul, Turkey
    Bioessays 33:742-8. 2011
  2. pmc Deletion of conserved protein phosphatases reverses defects associated with mitochondrial DNA damage in Saccharomyces cerevisiae
    Görkem Garipler
    Department of Molecular Biology and Genetics and School of Medicine, Koc University, Sariyer, Istanbul, 34450 Turkey
    Proc Natl Acad Sci U S A 111:1473-8. 2014
  3. doi request reprint Activation of the pleiotropic drug resistance pathway can promote mitochondrial DNA retention by fusion-defective mitochondria in Saccharomyces cerevisiae
    Nebibe Mutlu
    Department of Molecular Biology and Genetic, Koc University, Sariyer, Istanbul, 34450, Turkey
    G3 (Bethesda) 4:1247-58. 2014
  4. pmc Defects associated with mitochondrial DNA damage can be mitigated by increased vacuolar pH in Saccharomyces cerevisiae
    Görkem Garipler
    Department of Molecular Biology and Genetics, Koc University, Sariyer, Istanbul, 34450, Turkey
    Genetics 194:285-90. 2013
  5. doi request reprint Mutation of the mitochondrial large ribosomal RNA can provide pentamidine resistance to Saccharomyces cerevisiae
    Ş Tomris Örs
    Department of Molecular Biology and Genetics, Koc University, Sariyer, Istanbul 34450, Turkey
    Mitochondrion 18:7-11. 2014

Collaborators

  • Görkem Garipler
  • Nebibe Mutlu
  • Ş Tomris Örs
  • Emel Akdoğan
  • Nathan A Lack

Detail Information

Publications5

  1. doi request reprint Running on empty: does mitochondrial DNA mutation limit replicative lifespan in yeast?: Mutations that increase the division rate of cells lacking mitochondrial DNA also extend replicative lifespan in Saccharomyces cerevisiae
    Cory D Dunn
    Department of Molecular Biology and Genetics, Koc University, Istanbul, Turkey
    Bioessays 33:742-8. 2011
    ..These exciting, parallel findings imply a potential causal relationship between mtDNA mutation and replicative senescence. Furthermore, these results suggest more efficient methods for discovering genes that determine lifespan...
  2. pmc Deletion of conserved protein phosphatases reverses defects associated with mitochondrial DNA damage in Saccharomyces cerevisiae
    Görkem Garipler
    Department of Molecular Biology and Genetics and School of Medicine, Koc University, Sariyer, Istanbul, 34450 Turkey
    Proc Natl Acad Sci U S A 111:1473-8. 2014
    ..Our work highlights the important role that nutrient-responsive signaling pathways can play in determining the response to mitochondrial dysfunction. ..
  3. doi request reprint Activation of the pleiotropic drug resistance pathway can promote mitochondrial DNA retention by fusion-defective mitochondria in Saccharomyces cerevisiae
    Nebibe Mutlu
    Department of Molecular Biology and Genetic, Koc University, Sariyer, Istanbul, 34450, Turkey
    G3 (Bethesda) 4:1247-58. 2014
    ..Our results reveal an intriguing genetic connection between pleiotropic drug resistance and mitochondrial dynamics. ..
  4. pmc Defects associated with mitochondrial DNA damage can be mitigated by increased vacuolar pH in Saccharomyces cerevisiae
    Görkem Garipler
    Department of Molecular Biology and Genetics, Koc University, Sariyer, Istanbul, 34450, Turkey
    Genetics 194:285-90. 2013
    ..Furthermore, elevating vacuolar pH increases proliferation after mtDNA deletion and reverses the protein import defect of mitochondria lacking DNA...
  5. doi request reprint Mutation of the mitochondrial large ribosomal RNA can provide pentamidine resistance to Saccharomyces cerevisiae
    Ş Tomris Örs
    Department of Molecular Biology and Genetics, Koc University, Sariyer, Istanbul 34450, Turkey
    Mitochondrion 18:7-11. 2014
    ..Our results provide a potential rationale for the toxicity of this drug to patients, and we discuss whether blockade of mitochondrial translation is the mechanism by which pathogenic fungi or protists are killed by pentamidine. ..