Altan Onat

Summary

Affiliation: Istanbul University
Country: Turkey

Publications

  1. ncbi [Lipoprotein (a) in a population-based study: more significant in Turkish women than men?]
    Altan Onat
    Turkish Society of Cardiology, 80630 Etiler, Istanbul, Turkey
    Anadolu Kardiyol Derg 5:271-7. 2005
  2. ncbi Moderate and heavy alcohol consumption among Turks: long-term impact on mortality and cardiometabolic risk
    Altan Onat
    Turkish Society of Cardiology, Cerrahpasa Medical Faculty, Istanbul University, Istanbul, Turkey
    Turk Kardiyol Dern Ars 37:83-90. 2009
  3. ncbi Serum adiponectin confers little protection against diabetes and hypertension in Turkish men
    Altan Onat
    Turkish Society of Cardiology, Istanbul, Turkey
    Obesity (Silver Spring) 17:564-70. 2009
  4. doi Independent prediction of metabolic syndrome by plasma fibrinogen in men, and predictors of elevated levels
    Altan Onat
    Turkish Society of Cardiology, Istanbul University, Turkey
    Int J Cardiol 135:211-7. 2009
  5. ncbi Serum gamma glutamyltransferase as a marker of metabolic syndrome and coronary disease likelihood in nondiabetic middle-aged and elderly adults
    Altan Onat
    Turkish Society of Cardiology, Istanbul University, Istanbul, Turkey
    Prev Med 43:136-9. 2006
  6. ncbi Association between mild renal dysfunction and insulin resistance or metabolic syndrome in a random nondiabetic population sample
    Altan Onat
    Turkish Society of Cardiology, Istanbul University, Istanbul, Turkey
    Kidney Blood Press Res 30:88-96. 2007
  7. doi Impaired protection against diabetes and coronary heart disease by high-density lipoproteins in Turks
    Altan Onat
    Turkish Society of Cardiology, Cerrahpasa Medical Faculty, Istanbul University, Istanbul 34384, Turkey
    Metabolism 58:1393-9. 2009
  8. doi Predictive value of prehypertension for metabolic syndrome, diabetes, and coronary heart disease among Turks
    Altan Onat
    Turkish Society of Cardiology, Cerrahpasa Medical Faculty, Istanbul University, Istanbul, Turkey
    Am J Hypertens 21:890-5. 2008
  9. ncbi Cross-sectional study of complement C3 as a coronary risk factor among men and women
    Altan Onat
    Turkish Society of Cardiology, Department of Cardiology, Istanbul University, Istanbul, Turkey
    Clin Sci (Lond) 108:129-35. 2005
  10. doi Minor allele of the APOA4 gene T347S polymorphism predisposes to obesity in postmenopausal Turkish women
    Filiz Guclu-Geyik
    Department of Genetics, Institute for Experimental Medicine, Istanbul University, Vakif Gureba cad, 34080, Sehremini, Istanbul, Turkey
    Mol Biol Rep 39:10907-14. 2012

Detail Information

Publications80

  1. ncbi [Lipoprotein (a) in a population-based study: more significant in Turkish women than men?]
    Altan Onat
    Turkish Society of Cardiology, 80630 Etiler, Istanbul, Turkey
    Anadolu Kardiyol Derg 5:271-7. 2005
    ....
  2. ncbi Moderate and heavy alcohol consumption among Turks: long-term impact on mortality and cardiometabolic risk
    Altan Onat
    Turkish Society of Cardiology, Cerrahpasa Medical Faculty, Istanbul University, Istanbul, Turkey
    Turk Kardiyol Dern Ars 37:83-90. 2009
    ..The impact of alcohol consumption on various outcomes was prospectively evaluated in the participants of the Turkish Adult Risk Factor Study...
  3. ncbi Serum adiponectin confers little protection against diabetes and hypertension in Turkish men
    Altan Onat
    Turkish Society of Cardiology, Istanbul, Turkey
    Obesity (Silver Spring) 17:564-70. 2009
    ..This dysfunction may underlie also the association of adiponectin levels with MetS in men to be independent of the MetS components...
  4. doi Independent prediction of metabolic syndrome by plasma fibrinogen in men, and predictors of elevated levels
    Altan Onat
    Turkish Society of Cardiology, Istanbul University, Turkey
    Int J Cardiol 135:211-7. 2009
    ..0 g/L) fibrinogen at follow-up (p<0.05 in all)...
  5. ncbi Serum gamma glutamyltransferase as a marker of metabolic syndrome and coronary disease likelihood in nondiabetic middle-aged and elderly adults
    Altan Onat
    Turkish Society of Cardiology, Istanbul University, Istanbul, Turkey
    Prev Med 43:136-9. 2006
    ..Doubling in activity is associated with a (largely waist girth mediated) rise by over one-half in the multiadjusted MS likelihood, and by nearly one-half in the CHD likelihood, independent of waist girth and major risk factors...
  6. ncbi Association between mild renal dysfunction and insulin resistance or metabolic syndrome in a random nondiabetic population sample
    Altan Onat
    Turkish Society of Cardiology, Istanbul University, Istanbul, Turkey
    Kidney Blood Press Res 30:88-96. 2007
    ..The association of mild renal dysfunction (estimated glomerular filtration rate [eGFR] 60-89.9 ml/min/1.73 m(2)) with insulin resistance (IR) or metabolic syndrome (MS) needs be investigated in a population in which MS prevails...
  7. doi Impaired protection against diabetes and coronary heart disease by high-density lipoproteins in Turks
    Altan Onat
    Turkish Society of Cardiology, Cerrahpasa Medical Faculty, Istanbul University, Istanbul 34384, Turkey
    Metabolism 58:1393-9. 2009
    ..This highly important observation may result from a setting of prevailing chronic subclinical inflammation...
  8. doi Predictive value of prehypertension for metabolic syndrome, diabetes, and coronary heart disease among Turks
    Altan Onat
    Turkish Society of Cardiology, Cerrahpasa Medical Faculty, Istanbul University, Istanbul, Turkey
    Am J Hypertens 21:890-5. 2008
    ..Predictors of prehypertension and the latter's significance in predicting metabolic syndrome (MetS), type 2 diabetes (DM), and incident coronary heart disease (CHD) need further exploration...
  9. ncbi Cross-sectional study of complement C3 as a coronary risk factor among men and women
    Altan Onat
    Turkish Society of Cardiology, Department of Cardiology, Istanbul University, Istanbul, Turkey
    Clin Sci (Lond) 108:129-35. 2005
    ..Unlike CRP and fibrinogen, C3 was preferentially associated with waist girth and serum triacylglycerols...
  10. doi Minor allele of the APOA4 gene T347S polymorphism predisposes to obesity in postmenopausal Turkish women
    Filiz Guclu-Geyik
    Department of Genetics, Institute for Experimental Medicine, Istanbul University, Vakif Gureba cad, 34080, Sehremini, Istanbul, Turkey
    Mol Biol Rep 39:10907-14. 2012
    ..The APOA4 S347 allele predisposes to obesity and high waist circumference in Turkish postmenopausal women. ApoB levels are lower only in men in S347 allele carriers...
  11. doi Serum γ-glutamyltransferase: independent predictor of risk of diabetes, hypertension, metabolic syndrome, and coronary disease
    Altan Onat
    Department of Cardiology, Cerrahpasa Medical Faculty, Istanbul University, Istanbul, Turkey
    Obesity (Silver Spring) 20:842-8. 2012
    ..Higher serum total bilirubin levels were protective against CHD risk in women. We conclude that elevated serum GGT confers, additively to BMI, risk of hypertension, MetS, and type 2 diabetes but only mediates adiposity against CHD risk...
  12. ncbi Serum uric acid is a determinant of metabolic syndrome in a population-based study
    Altan Onat
    Turkish Society of Cardiology, Istanbul University, Istanbul, Turkey
    Am J Hypertens 19:1055-62. 2006
    ..Determination of serum uric acid concentrations and role in risk of metabolic syndrome (MS) were investigated in 1877 participants in a cross-sectional population-based study including a brief follow-up...
  13. doi Neck circumference as a measure of central obesity: associations with metabolic syndrome and obstructive sleep apnea syndrome beyond waist circumference
    Altan Onat
    Turkish Society of Cardiology, Istanbul University, Istanbul, Turkey
    Clin Nutr 28:46-51. 2009
    ..To investigate the relationship of neck circumference (NC) to metabolic syndrome (MetS) and obstructive sleep apnea syndrome (OSAS) and whether it adds information to that provided by waist circumference...
  14. ncbi Obstructive sleep apnea syndrome is associated with metabolic syndrome rather than insulin resistance
    Altan Onat
    Turkish Soc Cardiology, Istanbul, Turkey
    Sleep Breath 11:23-30. 2007
    ..OSAS is associated with MS rather than IR per se. Relatively high prevalence of OSAS is observed in Turkish women in whom it is significantly associated with CHD...
  15. ncbi Determinants and definition of abdominal obesity as related to risk of diabetes, metabolic syndrome and coronary disease in Turkish men: a prospective cohort study
    Altan Onat
    Turkish Society of Cardiology, Istanbul University, Istanbul, Turkey
    Atherosclerosis 191:182-90. 2007
    ..We aimed to investigate determinants of abdominal obesity and its clinical impact on metabolic syndrome (MS), diabetes (DM) and coronary heart disease (CHD) in men...
  16. doi Visceral adipose tissue and body fat mass: predictive values for and role of gender in cardiometabolic risk among Turks
    Altan Onat
    Department of Cardiology, Cerrahpasa Medical Faculty, Istanbul University, Istanbul, Turkey
    Nutrition 26:382-9. 2010
    ..We investigated the predictive values of visceral adipose tissue area (VAT) and body fat mass for a composite endpoint consisting of type 2 diabetes and coronary heart disease and for incident metabolic syndrome...
  17. ncbi CETP TaqIB polymorphism in Turkish adults: association with dyslipidemia and metabolic syndrome
    Bilge Ozsait
    Department of Genetics, Institute for Experimental Medical Research, Istanbul University, Istanbul, Turkey
    Anadolu Kardiyol Derg 8:324-30. 2008
    ..In this study, our aim was to investigate the association of cholesterol ester transfer protein (CETP) TaqIB polymorphism with the likelihood of metabolic syndrome (MetS)...
  18. doi Associations of alcohol consumption with blood pressure, lipoproteins, and subclinical inflammation among Turks
    Altan Onat
    Turkish Society of Cardiology, Istanbul, Turkey
    Alcohol 42:593-601. 2008
    ..Only women respond with lower triglycerides and CRP, whereas men show a log-linear positive association of drinking categories with BP, LDL cholesterol, apoB, and CRP...
  19. pmc Relatively high levels of serum adiponectin in obese women, a potential indicator of anti-inflammatory dysfunction: relation to sex hormone-binding globulin
    Altan Onat
    Turkish Society of Cardiology, Istanbul University, Istanbul, Turkey
    Int J Biol Sci 4:208-14. 2008
    ..Whereas in men HDL-cholesterol and CRP were covariates of adiponectin (both p<0.01), SHBG and apolipoprotein B positively associated in women (p<0.001), independent of BMI and fasting insulin levels...
  20. doi Serum complement C3: a determinant of cardiometabolic risk, additive to the metabolic syndrome, in middle-aged population
    Altan Onat
    Turkish Society of Cardiology, Istanbul, Turkey
    Metabolism 59:628-34. 2010
    ..Levels contribute, additively to MetS, to the diabetes risk in women alone...
  21. ncbi Predictors of abdominal obesity and high susceptibility of cardiometabolic risk to its increments among Turkish women: a prospective population-based study
    Altan Onat
    Turkish Society of Cardiology, Istanbul, Turkey
    Metabolism 56:348-56. 2007
    ..A waist girth of 83 cm or greater should be regarded as abdominal obesity among Turkish women...
  22. ncbi [Incidence, prevalence, and mortality estimates for chronic atrial fibrillation in Turkish adults]
    Huseyin Uyarel
    Department of Cardiology, Dr Siyami Ersek Cardiovascular Surgery Center, Istanbul, Turkey
    Turk Kardiyol Dern Ars 36:214-22. 2008
    ..We investigated the incidence, prevalence, and mortality of chronic atrial fibrillation (AF) in Turkish adults...
  23. doi Serum total and high-density lipoprotein phospholipid levels in a population-based study and relationship to risk of metabolic syndrome and coronary disease
    Gulay Hergenc
    Biology Department, Yildiz Technical University, Istanbul, Turkey
    Angiology 59:26-35. 2008
    ..Plasma TPL levels point to an adverse relationship to MS, whereas their role in CHD risk needs further investigation. HDL-pls, in contrast, mark substantial protection from MS as well as from CHD...
  24. doi High absolute coronary disease risk among Turks: involvement of risk factors additional to conventional ones
    Altan Onat
    Turkish Society of Cardiology, Istanbul, Turkey
    Cardiology 115:297-306. 2010
    ..To confirm previous findings on excess absolute coronary heart disease (CHD) risk among Turks...
  25. doi Smoking inhibits visceral fat accumulation in Turkish women: relation of visceral fat and body fat mass to atherogenic dyslipidemia, inflammatory markers, insulin resistance, and blood pressure
    Altan Onat
    Turkish Society of Cardiology, Istanbul, Turkey
    Metabolism 58:963-70. 2009
    ..Visceral fat is better associated than fat mass with atherogenic dyslipidemia and, in men, with apolipoprotein B. Thus, sex interacts with the dynamics of cardiometabolic risk...
  26. ncbi Serum sex hormone-binding globulin, a determinant of cardiometabolic disorders independent of abdominal obesity and insulin resistance in elderly men and women
    Altan Onat
    Turkish Society of Cardiology, Istanbul University, 34384 Istanbul, Turkey
    Metabolism 56:1356-62. 2007
    ..Low SHBG may be an important independent factor for cardiometabolic risk, particularly in women...
  27. ncbi Prevalence, incidence, predictors and outcome of type 2 diabetes in Turkey
    Altan Onat
    Cerrahpasa Medical Faculty, Istanbul University, Istanbul, Turkey
    Anadolu Kardiyol Derg 6:314-21. 2006
    ..To investigate prospectively the incidence, certain predictors and outcomes of type 2 diabetes (DM), as well as to determine its prevalence cross-sectionally, in a representative sample of Turkish men and women...
  28. ncbi Apolipoprotein C-III, a strong discriminant of coronary risk in men and a determinant of the metabolic syndrome in both genders
    Altan Onat
    Turkish Society of Cardiology, Istanbul University, Nisbetiye cad 37 24, Etiler, Turkey
    Atherosclerosis 168:81-9. 2003
    ....
  29. ncbi Fasting, non-fasting glucose and HDL dysfunction in risk of pre-diabetes, diabetes, and coronary disease in non-diabetic adults
    Altan Onat
    Department of Cardiology Cerrahpaşa Medical Faculty, Istanbul University, Nisbetiye cad 59 24, Etiler, 34335, Istanbul, Turkey
    Acta Diabetol 50:519-28. 2013
    ..IGT independently predicts CHD risk, especially in women. HDL dysfunction associated with low-grade inflammation is a co-determinant of pre-diabetic states and their progression to diabetes...
  30. doi Gender- and obesity-specific effect of apolipoprotein C3 gene (APOC3) -482C>T polymorphism on triglyceride concentration in Turkish adults
    Neslihan Coban
    Department of Genetics, Institute for Experimental Medical Research, Istanbul University, Vakif Gureba Cad Sehremini, Istanbul, Turkey
    Clin Chem Lab Med 50:285-92. 2012
    ..This study aimed to investigate such association between the APOC3 -482C>T polymorphism and cardiometabolic risk factors in the turkish adult risk factor (TARF) study cohort, stratifying by gender and obesity...
  31. ncbi Plasma triglycerides, an independent predictor of cardiovascular disease in men: a prospective study based on a population with prevalent metabolic syndrome
    Altan Onat
    Turkish Society of Cardiology, Istanbul, Turkey
    Int J Cardiol 108:89-95. 2006
    ..A total of 120 fatal and 221 new nonfatal CVD occurred among adults (mean age 43+/-14) during a mean 9.3 years of follow-up...
  32. ncbi Negative T wave in chest lead V1: relation to sex and future cardiovascular risk factors
    Teoman Onat
    Department of Pediatric Cardiology, Cerrahpaşa Medicine Faculty of İstanbul University, Istanbul, Turkey
    Turk Kardiyol Dern Ars 36:513-8. 2008
    ..This study was designed to determine the prevalence of negative T waves in chest lead V1 in an adult cohort...
  33. doi Lifestyle and metabolic determinants of incident hypertension, with special reference to cigarette smoking: a longitudinal population-based study
    Altan Onat
    Department of Cardiology, Cerrahpasa Medical Faculty, Istanbul University, Istanbul, Turkey
    Am J Hypertens 22:156-62. 2009
    ..Lifestyle and metabolic determinants of incident hypertension in a population with a high prevalence of metabolic syndrome (MetS) need to be further assessed...
  34. doi Serum folate is associated with coronary heart disease independently of homocysteine in Turkish men
    Altan Onat
    Turkish Society of Cardiology, Istanbul, Turkey Cerrahpaşa Medical Faculty, Istanbul University, Istanbul, Turkey
    Clin Nutr 27:732-9. 2008
    ..These associations and the influence of serum folate and vitamin B(12) thereupon were addressed separately in genders...
  35. ncbi Discordance between insulin resistance and metabolic syndrome: features and associated cardiovascular risk in adults with normal glucose regulation
    Altan Onat
    Turkish Society of Cardiology, Istanbul University, 34335 Istanbul, Turkey
    Metabolism 55:445-52. 2006
    ..Insulin resistance without MS tends to implicate in middle-aged and elderly Turkish men roughly a 2-fold CVD risk, corresponding to 50% excess risk per 1 SD in HOMA index, independent of MS and important covariates...
  36. doi Apolipoprotein A-I positively associated with diabetes in women independently of apolipoprotein E genotype and apolipoprotein B levels
    Altan Onat
    Turkish Society of Cardiology, Istanbul University, Istanbul, Turkey Cerrahpaşa Medical Faculty, Istanbul University, Istanbul, Turkey
    Nutrition 26:975-80. 2010
    ....
  37. doi Preheparin serum lipoprotein lipase mass interacts with gender, gene polymorphism and, positively, with smoking
    Altan Onat
    Turkish Society of Cardiology, Istanbul, Turkey
    Clin Chem Lab Med 47:208-15. 2009
    ..Correlates of preheparin serum lipoprotein lipase (LPL) mass and its associations with the likelihood of metabolic syndrome (MS) and coronary heart disease (CHD) were investigated...
  38. ncbi Elevated LDL-cholesterol level predicts diabetes in centrally obese women but not men: relative roles of insulin resistance and central obesity
    Altan Onat
    Turkish Society of Cardiology, Istanbul University, Istanbul, Turkey
    Circ J 71:1463-7. 2007
    ..The 3,048 participants (aged > or =28 years) were free of DM at baseline, a representative sample of Turkish adults and were evaluated prospectively...
  39. doi The APOE -219G/T and +113G/C polymorphisms affect insulin resistance among Turks
    Evrim Komurcu-Bayrak
    Department of Genetics, Institute for Experimental Medicine, Istanbul University, 34080, Istanbul, Turkey
    Metabolism 60:655-63. 2011
    ..42-0.99) for HOMA of insulin resistance after adjusting for 8 covariates. APOE promoter polymorphisms and their diplotypes are independently related with serum fasting insulin levels and HOMA index among Turks...
  40. doi Gender-modulated impact of apolipoprotein A5 gene (APOA5) -1131T>C and c.56C>G polymorphisms on lipids, dyslipidemia and metabolic syndrome in Turkish adults
    Evrim Komurcu-Bayrak
    Department of Genetics, Institute for Experimental Medicine, Istanbul University, Istanbul, Turkey
    Clin Chem Lab Med 46:778-84. 2008
    ..56C>G polymorphisms [single nucleotide polymorphism (SNP)] with serum lipids, dyslipidemia [low high-density lipoprotein (HDL)/high triglyceride] and the risk for metabolic syndrome (MS) in the Turkish Adult Risk Factor study...
  41. doi High serum apolipoprotein E determines hypertriglyceridemic dyslipidemias, coronary disease and apoA-I dysfunctionality
    Altan Onat
    Turkish Society of Cardiology, Istanbul, Turkey
    Lipids 48:51-61. 2013
    ..Excess apoE reflects pro-inflammatory state and likely autoimmune activation...
  42. doi Impaired anti-inflammatory function of apolipoprotein A-II concentrations predicts metabolic syndrome and diabetes at 4 years follow-up in elderly Turks
    Altan Onat
    Turkish Society of Cardiology, Istanbul, Turkey
    Clin Chem Lab Med 47:1389-94. 2009
    ....
  43. ncbi Prospective epidemiologic evidence of a "protective" effect of smoking on metabolic syndrome and diabetes among Turkish women--without associated overall health benefit
    Altan Onat
    Turkish Society of Cardiology, Nisbetiye cad 37 24, Etiler 34335, Istanbul, Turkey
    Atherosclerosis 193:380-8. 2007
    ..Risks of incident CHD and overall mortality were significantly elevated in smoking men, but not in women, when adjusted for age, serum total cholesterol, elevated BP, DM and physical activity grade...
  44. doi Lipoprotein(a) is associated with coronary heart disease independent of metabolic syndrome
    Altan Onat
    Turkish Society of Cardiology, Istanbul, Turkey
    Coron Artery Dis 19:125-31. 2008
    ..To assess (i) the association between lipoprotein(a) [Lp(a)] with the likelihood of coronary heart disease and metabolic syndrome (MS) and (ii) its covariates in Turkish adults...
  45. ncbi [Age at death in the Turkish Adult Risk Factor Study: temporal trend and regional distribution at 56,700 person-years' follow-up]
    Altan Onat
    Turkish Society of Cardiology Department of Cardiology, Cerrahpasa Medical Faculty, Istanbul University, Istanbul, Turkey
    Turk Kardiyol Dern Ars 37:155-60. 2009
    ..We analyzed the temporal trend and regional distribution of age at all-cause death and the sex-specific and age-bracket defined coronary mortality in the 18-year follow-up of the Turkish Adult Risk Factor Study...
  46. doi "Atherogenic index of plasma" (log10 triglyceride/high-density lipoprotein-cholesterol) predicts high blood pressure, diabetes, and vascular events
    Altan Onat
    Turkish Society of Cardiology, Cerrahpasa Medical Faculty, Istanbul University, Nisbetiye cad 59 24, Etiler 34335, Istanbul, Turkey
    J Clin Lipidol 4:89-98. 2010
    ....
  47. doi [Regional distribution of all-cause mortality and coronary disease incidence in Turkey: findings of Turkish Adult Risk Factor survey 2010]
    Altan Onat
    Department of Cardiology, Cerrahpasa School of Medicine, Istanbul University, Istanbul, Turkey
    Turk Kardiyol Dern Ars 39:263-8. 2011
    ....
  48. ncbi Coronary disease risk curve of serum creatinine is linear in Turkish men, U-shaped in women
    Altan Onat
    Turkish Society of Cardiology, Istanbul, Turkey
    J Investig Med 61:27-33. 2013
    ..The highest levels of glomerular filtration rate are associated with increased coronary heart disease (CHD) risk, an issue we investigated in separate sexes in a population prone to metabolic syndrome...
  49. doi Predictive value of serum apolipoprotein B/LDL-cholesterol ratio in cardiometabolic risk: population-based cohort study
    Altan Onat
    Department of Cardiology, Cerrahpasa Medical Faculty, Istanbul University, Istanbul, Turkey
    Clin Biochem 43:1381-6. 2010
    ..We determined the independent predictive value of serum apolipoprotein (apo) B/LDL-cholesterol ratio for the risk of diabetes, metabolic syndrome (MetS) and coronary heart disease (CHD)...
  50. doi Dual activity of serum lipoprotein-associated phospholipase A(2) yielding positive and inverse associations with cardiometabolic risk
    Altan Onat
    Turkish Society of Cardiology, Istanbul, Turkey
    Clin Chem Lab Med 49:1349-57. 2011
    ..We determined major covariates of Lp-PLA(2) mass, and its associations with cardiometabolic disorders...
  51. ncbi [Major influence of dysfunctions of protective serum proteins on cardiometabolic risk among Turks and gender difference]
    Altan Onat
    Turkish Society of Cardiology Department of Cardiology, Cerrahpaşa Medicine Faculy of Istanbul University, Istanbul, Turkey
    Turk Kardiyol Dern Ars 37:425-34. 2009
    ....
  52. ncbi [Prospective validation in identical Turkish cohort of two metabolic syndrome definitions for predicting cardiometabolic risk and selection of most appropriate definition]
    Altan Onat
    Turkish Society of Cardiology Department of Cardiology, Cerrahpasa Medical Faculty, Istanbul University, Istanbul, Turkey
    Anadolu Kardiyol Derg 7:29-34. 2007
    ....
  53. ncbi The S447X variant of lipoprotein lipase gene is associated with metabolic syndrome and lipid levels among Turks
    Evrim Komurcu-Bayrak
    Department of Genetics, Institute for Experimental Medical Research, Istanbul University, Istanbul, Turkey
    Clin Chim Acta 383:110-5. 2007
    ..This is the first study examining this LPL variant in the Turkish population...
  54. ncbi Systolic, diastolic, and pulse pressures as coronary risk factors in a population with low cholesterol levels: a prospective 10-year evaluation
    Altan Onat
    Turkish Society of Cardiology, Istanbul University, Istanbul, Turkey
    Clin Cardiol 26:91-7. 2003
    ..Pulse pressure (PP) has recently been found to be predictive of subsequent cardiovascular, particularly coronary, events in some middle-aged and elderly populations...
  55. doi Serum C-reactive protein is an independent risk factor predicting cardiometabolic risk
    Altan Onat
    Turkish Society of Cardiology, Istanbul University, 34335 Etiler, Istanbul, Turkey
    Metabolism 57:207-14. 2008
    ..18-fold HR. C-reactive protein is both an independent significant predictor and a risk factor of cardiometabolic risk among Turkish adults, additive to MS components, whereby risk is modulated by sex, smoking habit, and apo B...
  56. ncbi Metabolic syndrome: major impact on coronary risk in a population with low cholesterol levels--a prospective and cross-sectional evaluation
    Altan Onat
    Turkish Society of Cardiology, Istanbul, Turkey
    Atherosclerosis 165:285-92. 2002
    ..It was estimated that MS was the culprit in just over half the cases of CHD in Turkey...
  57. ncbi Dyslipidemic hypertension: distinctive features and cardiovascular risk in a prospective population-based study
    Altan Onat
    Turkish Society of Cardiology, Biology Department, Nisbetiye cad 37 24 Etiler, 80630 Istanbul, Turkey
    Am J Hypertens 18:409-16. 2005
    ..High-normal or hypertensive values not meeting the other two criteria were designated as "simple hypertensives" (SH)...
  58. ncbi [Turkish Adult Risk Factor Survey 2007: decline in all-cause and coronary mortality continues]
    Altan Onat
    Department of Cardiology, Cerrahpasa Medical Faculty of Istanbul University, Istanbul, Turkey
    Turk Kardiyol Dern Ars 36:77-81. 2008
    ....
  59. ncbi [The Turkish Adult Risk Factor survey 2009: similar cardiovascular mortality in rural and urban areas]
    Altan Onat
    Türk Kardiyoloji Derneğu, Istanbul Universitesi Cerrahpaşa Tip Fakültesi Kardiyoloji Anabilim Dali, Istanbul, Turkey
    Turk Kardiyol Dern Ars 38:159-63. 2010
    ..We analyzed 2009 survey of the Turkish Adult Risk Factor (TARF) Study to assess the distribution of all-cause and cardiovascular mortality in urban and rural areas and sex-specific coronary mortality in the age-bracket of 45 to 74 years...
  60. doi Coronary disease risk and fasting glucose levels in a non-diabetic population
    Altan Onat
    Department of Cardiology, Cerrahpasa Medical Faculty, Istanbul University, Istanbul, Turkey
    Diabetes Res Clin Pract 91:220-5. 2011
    ..The increased CHD risk observed in individuals with lower compared with higher normal glucose concentrations is likely to be related to an associated pro-inflammatory state...
  61. doi Low-grade inflammation, and dysfunction of high-density lipoprotein and its apolipoproteins as a major driver of cardiometabolic risk
    Altan Onat
    Turkish Society of Cardiology, Istanbul University, Istanbul 34098, Turkey
    Metabolism 60:499-512. 2011
    ..The great impact in public health of the dysfunction of protective serum proteins requires individual clinical recognition, appropriate preventive measures, and delineation of management, including with anti-inflammatory drugs...
  62. doi Elevated serum uric acid in nondiabetic people mark pro-inflammatory state and HDL dysfunction and independently predicts coronary disease
    Altan Onat
    Turkish Society of Cardiology and Department of Cardiology, Cerrahpasa Medical Faculty, Istanbul University, Istanbul, Turkey
    Clin Rheumatol 32:1767-75. 2013
    ..CHD risk is independently predicted by elevated UA levels in nondiabetic men and is modulated by MetS and gender...
  63. ncbi Family income a strong predictor of coronary heart disease events but not of overall deaths among Turkish adults: a 12-year prospective study
    Ibrahim Keles
    Turkish Society of Cardiology, Ministry of Justice, Istanbul, Turkey
    Prev Med 37:171-6. 2003
    ..The objective of this study was to assess whether family income affected future deaths and coronary heart disease (CHD) events...
  64. doi APOC3 -482C>T polymorphism, circulating apolipoprotein C-III and smoking: interrelation and roles in predicting type-2 diabetes and coronary disease
    Altan Onat
    Department of Cardiology, Cerrahpasa Medical Faculty, Istanbul University, Istanbul, Turkey
    Clin Biochem 44:391-6. 2011
    ..We determined the relationship of smoking status on APOC3 -482C>T polymorphism and apolipoprotein C-III (apoC-III) concentrations and the latter two parameters' influence on risk of diabetes and coronary heart disease (CHD)...
  65. ncbi Evidence for a complex risk profile in obese postmenopausal Turkish women with hypertriglyceridaemia and elevated apolipoprotein B
    Altan Onat
    Turkish Society of Cardiology, Department of Cardiology, Cerrahpasa Medical Faculty, Istanbul University, Istanbul
    Clin Sci (Lond) 107:97-104. 2004
    ..In summary, in Turkish women, apoB was linked with a complex array of proatherogenic risk factors, and hypertriglyceridaemia with elevated apoB was associated with a higher risk of coronary disease...
  66. ncbi [Turkey's 2009 output of cardiovascular publications shows a four-year regression]
    Altan Onat
    Turkish Society of Cardiology, Istanbul, Turkey
    Turk Kardiyol Dern Ars 38:57-68. 2010
    ....
  67. doi Metabolic syndrome: nature, therapeutic solutions and options
    Altan Onat
    Cerrahpasa Medical Faculty, Istanbul University, Istanbul, Turkey
    Expert Opin Pharmacother 12:1887-1900. 2011
    ..The significance of MetS lies in its close association with the risk of type 2 diabetes and cardiovascular disease (CVD). This field being an evolving one necessitated the current review...
  68. ncbi Lipids, lipoproteins and apolipoproteins among turks, and impact on coronary heart disease
    Altan Onat
    Cerrahpasa Medical Faculty, Istanbul University, Turkish Society of Cardiology, Istanbul, Turkey
    Anadolu Kardiyol Derg 4:236-45. 2004
    ....
  69. doi Complement C3 and cleavage products in cardiometabolic risk
    Altan Onat
    Cardiology Department, Cerrahpasa Medical Faculty, Istanbul University, Istanbul, Turkey
    Clin Chim Acta 412:1171-9. 2011
    ..These observations have clinical and public health implications...
  70. ncbi Fasting insulin levels independently associated with coronary heart disease in non-diabetic Turkish men and women
    Altan Onat
    Department of Cardiology, Cerrahpasa Medical Faculty, Istanbul University, Istanbul, Turkey
    Int J Cardiol 86:61-9. 2002
    ....
  71. ncbi [Turkey's articles in cardiovascular medicine displayed quantitative and qualitative improvements in 2008]
    Altan Onat
    Türk Kardiyoloji Derneği, Istanbul Universitesi Cerrahpaşa Tip Fakültesi Kardiyoloji Anabilim Dali, Istanbul, Turkey
    Turk Kardiyol Dern Ars 37:61-75. 2009
    ....
  72. ncbi Sex difference in development of diabetes and cardiovascular disease on the way from obesity and metabolic syndrome
    Altan Onat
    Turkish Society of Cardiology, Istanbul University, 34384 Istanbul
    Metabolism 54:800-8. 2005
    ..The objective of this study was to investigate sex-specific differences existing on the way from (abdominal) obesity and metabolic syndrome (MS) to type 2 diabetes mellitus (DM) and cardiovascular disease (CVD)...
  73. ncbi Serum asymmetric dimethylarginine levels among Turks: association with metabolic syndrome in women and tendency to decrease in smokers
    Altan Onat
    Department of Cardiology, Cerrahpasa Medical Faculty of Istanbul University, Istanbul
    Turk Kardiyol Dern Ars 36:7-13. 2008
    ..We investigated serum asymmetric dimethylarginine (ADMA) levels and their association with smoking, metabolic syndrome (MS), and coronary heart disease (CHD) among Turkish adults...
  74. ncbi [On the criteria of metabolic syndrome in predicting incident coronary disease and diabetes in Turkish adults/abdominal obesity and cardiometabolic risk]
    Altan Onat
    Anadolu Kardiyol Derg 7:212-3. 2007
  75. ncbi [Turkey's articles in cardiovascular medicine were stagnant in 2007]
    Altan Onat
    Türk Kardiyoloji Derneği, Istanbul Universitesi Cerrahpaşa Tip Fakültesi Kardiyoloji Anabilim Dali, Istanbul
    Turk Kardiyol Dern Ars 36:51-65. 2008
    ..Unless new reforms are put in place, short-to-mid-term future will continue to cause disappointment about these institutions...
  76. ncbi Reduced asymmetric dimethylarginine (ADMA) levels mediate in the protection from metabolic syndrome by smoking
    Altan Onat
    Atherosclerosis 196:479-80. 2008
  77. ncbi Guideline implementation in a multicenter study with an estimated 44% relative cardiovascular event risk reduction
    Altan Onat
    Istanbul University Cerrahpasa, Turkey
    Clin Cardiol 26:243-9. 2003
    ..The extent of cardiovascular risk reduction by implementing coronary prevention guidelines needs to be documented in various population samples...
  78. ncbi [Serum apolipoprotein B is superior to LDL-cholesterol level in predicting incident coronary disease among Turks]
    Altan Onat
    Türk Kardiyoloji Derneği, Turkiye
    Anadolu Kardiyol Derg 7:128-33. 2007
    ..Whether apo B/apo A-I ratio has advantage over apo B in this prediction constitutes a secondary aim...
  79. ncbi High density lipoprotein cholesterol in coronary artery patients: is it as low as expected?
    Altan Onat
    Anadolu Kardiyol Derg 6:92-3; author reply 93. 2006
  80. ncbi On the coronary heart disease mortality in Turkey
    Altan Onat
    Atherosclerosis 163:203-4. 2002